General Information of the Compound
Compound ID
CP0450401
Compound Name
N-[5-(4-chlorobenzoyl)-4-phenyl-1,3-thiazol-2-yl]-4-methylbenzamide
    Show/Hide
Structure
Formula
C24H17ClN2O2S
Molecular Weight
432.932
Canonical SMILES
Cc1ccc(cc1)C(=O)Nc1nc(c(s1)C(=O)c1ccc(Cl)cc1)-c1ccccc1
    Show/Hide
InChI
InChI=1S/C24H17ClN2O2S/c1-15-7-9-18(10-8-15)23(29)27-24-26-20(16-5-3-2-4-6-16)22(30-24)21(28)17-11-13-19(25)14-12-17/h2-14H,1H3,(H,26,27,29)
    Show/Hide
InChIKey
VIFNFZUIGYFVAV-UHFFFAOYSA-N
Physicochemical Property
logP
6.25522
Rotatable Bonds
5
Heavy Atom Count
30
Polar Areas
59.06
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 46228973
ChEMBL ID
CHEMBL592681
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01278, Adenosine receptor A2b
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS