General Information of the Compound
Compound ID
CP0394632
Compound Name
N-benzhydryl-5-[(3,4-dimethoxyphenyl)methylamino]-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide
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Structure
Formula
C32H28N6O4
Molecular Weight
560.614
Canonical SMILES
COc1ccc(CNc2ncc(C(=O)NC(c3ccccc3)c3ccccc3)c3nc(nn23)-c2ccco2)cc1OC
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InChI
InChI=1S/C32H28N6O4/c1-40-25-16-15-21(18-27(25)41-2)19-33-32-34-20-24(30-36-29(37-38(30)32)26-14-9-17-42-26)31(39)35-28(22-10-5-3-6-11-22)23-12-7-4-8-13-23/h3-18,20,28H,19H2,1-2H3,(H,33,34)(H,35,39)
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InChIKey
MWOWEAQGGNMMNY-UHFFFAOYSA-N
Physicochemical Property
logP
5.533
Rotatable Bonds
10
Heavy Atom Count
42
Polar Areas
115.81
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
9
Complexity
42

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 145989440
ChEMBL ID
CHEMBL4293454
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00840, Adenosine receptor A1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 122 nM
   TI
   LI
   LO
   TS
Protein ID: PT00862, Adenosine receptor A2a
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 137 nM
   TI
   LI
   LO
   TS
Protein ID: PT01278, Adenosine receptor A2b
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 30000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 69.9 nM
   TI
   LI
   LO
   TS