Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[4-chloro-3-(2,6-dioxo-1,3-dipropyl-7H-purin-8-yl)-5-methylpyrazol-1-yl]-N-(4-chlorophenyl)acetamide
    Show/Hide
 PubChem ID
CID: 135874432
SID: 50081943
Canonical SMILES
CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)-c1nn(CC(=O)Nc2ccc(Cl)cc2)c(C)c1Cl
    Show/Hide
Compound Formula C23H25Cl2N7O3
Compound Structure
Protein Name
 Protein Info 
Adenosine receptor A2b
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Nucleotide-like receptor (family A GPCR)
>
Adenosine receptor
Uniprot ID
P29275
Gene Name
ADORA2B
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 > 1000 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 222 nM
   TI
   LI
   LO
   TS