General Information of the Compound
Compound ID
CP0928976
Compound Name
2-(4-(2-(2,4-dioxo-1,3-dipropyl-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(2-morpholinoethyl)acetamide
    Show/Hide
Structure
Formula
C30H43N7O5
Molecular Weight
581.718
Canonical SMILES
CCCn1c(=O)c2c(nc3n2CCCN3CCc2ccc(OCC(=O)NCCN3CCOCC3)cc2)n(CCC)c1=O
    Show/Hide
InChI
InChI=1S/C30H43N7O5/c1-3-12-36-27-26(28(39)37(13-4-2)30(36)40)35-15-5-14-34(29(35)32-27)16-10-23-6-8-24(9-7-23)42-22-25(38)31-11-17-33-18-20-41-21-19-33/h6-9H,3-5,10-22H2,1-2H3,(H,31,38)
    Show/Hide
InChIKey
WIFPAFBKIWYNGZ-UHFFFAOYSA-N
Physicochemical Property
logP
1.4597
Rotatable Bonds
13
Heavy Atom Count
42
Polar Areas
115.86
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
11
Complexity
42

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 145993147
ChEMBL ID
CHEMBL4287298
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01278, Adenosine receptor A2b
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 911 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS