General Information of the Compound
Compound ID
CP0428857
Compound Name
2-(2-Furyl)-7-n-pentylcarbonylamino-5-phenoxy[1,2,4]-triazolo[1,5-a]-[1,3,5]triazine
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Structure
Formula
C20H20N6O3
Molecular Weight
392.419
Canonical SMILES
CCCCCC(=O)Nc1nc(Oc2ccccc2)nc2nc(nn12)-c1ccco1
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InChI
InChI=1S/C20H20N6O3/c1-2-3-5-12-16(27)21-18-23-20(29-14-9-6-4-7-10-14)24-19-22-17(25-26(18)19)15-11-8-13-28-15/h4,6-11,13H,2-3,5,12H2,1H3,(H,21,22,23,24,25,27)
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InChIKey
VBPFFNMUFRTXON-UHFFFAOYSA-N
Physicochemical Property
logP
4.0904
Rotatable Bonds
8
Heavy Atom Count
29
Polar Areas
107.44
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46885517
ChEMBL ID
CHEMBL1089439
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01278, Adenosine receptor A2b
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 > 100000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 2200 nM
   TI
   LI
   LO
   TS