General Information of the Compound
Compound ID
CP0424771
Compound Name
8-[2-[4-[2-(diethylamino)ethoxy]phenyl]ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
    Show/Hide
Structure
Formula
C24H34N6O3
Molecular Weight
454.575
Canonical SMILES
CCN(CC)CCOc1ccc(CCN2CCn3c(C2)nc2n(C)c(=O)n(C)c(=O)c32)cc1
    Show/Hide
InChI
InChI=1S/C24H34N6O3/c1-5-28(6-2)15-16-33-19-9-7-18(8-10-19)11-12-29-13-14-30-20(17-29)25-22-21(30)23(31)27(4)24(32)26(22)3/h7-10H,5-6,11-17H2,1-4H3
    Show/Hide
InChIKey
XUFLIVVUGPRULF-UHFFFAOYSA-N
Physicochemical Property
logP
1.2126
Rotatable Bonds
9
Heavy Atom Count
33
Polar Areas
77.53
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
9
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 127043671
ChEMBL ID
CHEMBL3827075
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01278, Adenosine receptor A2b
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS