General Information of the Compound
Compound ID
CP0419912
Compound Name
8-[2-[4-[2-(dimethylamino)ethoxy]phenyl]ethyl]-1,3-dimethyl-7,9-dihydro-6H-purino[7,8-a]pyrazine-2,4-dione
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Structure
Formula
C22H30N6O3
Molecular Weight
426.521
Canonical SMILES
CN(C)CCOc1ccc(CCN2CCn3c(C2)nc2n(C)c(=O)n(C)c(=O)c32)cc1
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InChI
InChI=1S/C22H30N6O3/c1-24(2)13-14-31-17-7-5-16(6-8-17)9-10-27-11-12-28-18(15-27)23-20-19(28)21(29)26(4)22(30)25(20)3/h5-8H,9-15H2,1-4H3
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InChIKey
LBVUBDZTRAQKDJ-UHFFFAOYSA-N
Physicochemical Property
logP
0.4324
Rotatable Bonds
7
Heavy Atom Count
31
Polar Areas
77.53
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
9
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 127043831
ChEMBL ID
CHEMBL3827216
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01278, Adenosine receptor A2b
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS