General Information of the Compound
Compound ID
CP0883748
Compound Name
2-(4-(2-(2,4-dioxo-1,3-dipropyl-1,2,3,4,7,8-hexahydropyrimido[2,1-f]purin-9(6H)-yl)ethyl)phenoxy)-N-(4-sulfamoylphenethyl)acetamide
    Show/Hide
Structure
Formula
C32H41N7O6S
Molecular Weight
651.79
Canonical SMILES
CCCn1c(=O)c2c(nc3n2CCCN3CCc2ccc(OCC(=O)NCCc3ccc(S(N)(=O)=O)cc3)cc2)n(CCC)c1=O
    Show/Hide
InChI
InChI=1S/C32H41N7O6S/c1-3-17-38-29-28(30(41)39(18-4-2)32(38)42)37-20-5-19-36(31(37)35-29)21-15-24-6-10-25(11-7-24)45-22-27(40)34-16-14-23-8-12-26(13-9-23)46(33,43)44/h6-13H,3-5,14-22H2,1-2H3,(H,34,40)(H2,33,43,44)
    Show/Hide
InChIKey
WLWCSNFOHHXWJL-UHFFFAOYSA-N
Physicochemical Property
logP
2.0176
Rotatable Bonds
14
Heavy Atom Count
46
Polar Areas
163.55
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
11
Complexity
46

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 145981625
ChEMBL ID
CHEMBL4278326
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01278, Adenosine receptor A2b
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS