General Information of the Compound
Compound ID
CP0450338
Compound Name
9-[2-(4-hydroxyphenyl)ethyl]-1,3-dipropyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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Structure
Formula
C22H29N5O3
Molecular Weight
411.506
Canonical SMILES
CCCn1c2nc3N(CCc4ccc(O)cc4)CCCn3c2c(=O)n(CCC)c1=O
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InChI
InChI=1S/C22H29N5O3/c1-3-11-26-19-18(20(29)27(12-4-2)22(26)30)25-14-5-13-24(21(25)23-19)15-10-16-6-8-17(28)9-7-16/h6-9,28H,3-5,10-15H2,1-2H3
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InChIKey
ZIDPBCDCDVIDRH-UHFFFAOYSA-N
Physicochemical Property
logP
2.3381
Rotatable Bonds
7
Heavy Atom Count
30
Polar Areas
85.29
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 127043663
ChEMBL ID
CHEMBL3828658
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01278, Adenosine receptor A2b
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 663 nM
   TI
   LI
   LO
   TS
Protein ID: PT01279, Adenosine receptor A3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS