| Compound ID |
Compound Name |
Compound Formula |
|
CP0572854
|
methyl 1-[2-(3-hydroxyphenyl)ethyl]-4-(N-propanoylanilino)piperidine-4-carboxylate
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|
C24H30N2O4
|
1
|
| 1 |
EC50 = 0.014 nM
|
|
|
|
CP0469090
|
(1R,5S,9S)-5-(3-hydroxyphenyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-9-ol
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|
C22H27NO2
|
2
|
| 1 |
EC50 = 0.017 nM
|
|
|
| 2 |
EC50 = 6.08 nM
|
|
|
|
CP0402282
|
methyl 1-[2-(4-hydroxyphenyl)ethyl]-4-(N-propanoylanilino)piperidine-4-carboxylate
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|
C24H30N2O4
|
1
|
| 1 |
EC50 = 0.028 nM
|
|
|
|
CP0569068
|
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-2-(furan-3-yl)-9-[4-(hydroxymethyl)benzoyl]oxy-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C29H32O9
|
1
|
| 1 |
EC50 = 0.03 nM
|
|
|
|
CP0837174
|
Trans-2',3',4',9'-Tetrahydro-N,N-dimethyl-4-phenyl-spiro[cyclohexane-1,1'-pyrido[3,4-b]indol]-4-amine Dihydrochloride
Show/Hide
|
C24H30ClN3
|
2
|
| 1 |
EC50 = 0.2 nM
|
|
|
| 2 |
Ki = 0.39 nM
|
|
|
|
CP0435809
|
4-phenyl-9-(2-phenylethyl)-2-propan-2-yl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
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|
C25H32N2O2
|
2
|
| 1 |
EC50 = 0.2 nM
|
|
|
| 2 |
Ki = 1 nM
|
|
|
|
CP0421885
|
methyl 1-phenacyl-4-(N-propanoylanilino)piperidine-4-carboxylate
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|
C24H28N2O4
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0479295
|
ethyl 3-[(1S,5R,9R)-5-(3-hydroxyphenyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-9-yl]propanoate
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|
C27H35NO3
|
2
|
| 1 |
EC50 = 0.24 nM
|
|
|
| 2 |
EC50 = 11.57 nM
|
|
|
|
CP0550746
|
methyl 4-[N-(3-hydroxypropanoyl)anilino]-1-(2-phenylethyl)piperidine-4-carboxylate
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|
C24H30N2O4
|
1
|
| 1 |
EC50 = 0.28 nM
|
|
|
|
CP0043301
|
(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]-N-methylacetamido}-N-(2-hydroxyethyl)-3-phenylpropanamide
Show/Hide
|
C26H35N5O6
|
8
|
| 1 |
EC50 = 0.3 nM
|
|
|
| 2 |
EC50 = 0.6 nM
|
|
|
| 3 |
EC50 = 2 nM
|
|
|
| 4 |
EC50 = 42 nM
|
|
|
| 5 |
EC50 = 44.1 nM
|
|
|
| 6 |
EC50 = 199.53 nM
|
|
|
| 7 |
IC50 = 20 nM
|
|
|
| 8 |
Ki = 8.1 nM
|
|
|
|
CP0469092
|
methyl 3-[(1S,5R,9R)-5-(3-hydroxyphenyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-9-yl]propanoate
Show/Hide
|
C26H33NO3
|
2
|
| 1 |
EC50 = 0.46 nM
|
|
|
| 2 |
EC50 = 1.72 nM
|
|
|
|
CP0041772
|
4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-phthalazin-1-one
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|
C22H28N2O
|
1
|
| 1 |
EC50 = 0.51 nM
|
|
|
|
CP0261849
|
N-[(2S)-2-(4-benzylpiperidin-1-yl)propyl]-N-phenylpropanamide
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|
C24H32N2O
|
1
|
| 1 |
EC50 = 0.73 nM
|
|
|
|
CP0469087
|
3-[(1S,5R,9R)-2-(2-phenylethyl)-9-propyl-2-azabicyclo[3.3.1]nonan-5-yl]phenol
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|
C25H33NO
|
2
|
| 1 |
EC50 = 0.95 nM
|
|
|
| 2 |
EC50 > 25000 nM
|
|
|
|
CP0435824
|
2-ethyl-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
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|
C24H30N2O2
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
Ki = 3 nM
|
|
|
|
CP0518441
|
4-(2-chlorophenyl)-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
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|
C23H27ClN2O2
|
2
|
| 1 |
EC50 = 1 nM
|
|
|
| 2 |
Ki = 3 nM
|
|
|
|
CP0656335
|
trans-6'-Fluoro-4',9'-dihydro-N,N-dimethyl-4-phenyl-spiro[cyclohexane-1,1'(3'H)-pyrano[3,4-b]indol]-4-amine Hemicitrate
Show/Hide
|
C30H35FN2O8
|
2
|
| 1 |
EC50 = 1.2 nM
|
|
|
| 2 |
Ki = 0.7 nM
|
|
|
|
CP0858459
|
trans-4',9'-Dihydro-4-(dimethylamino)-4-phenyl-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-6'-ol Hemicitrate
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|
C30H36N2O9
|
2
|
| 1 |
EC50 = 1.2 nM
|
|
|
| 2 |
Ki = 0.4 nM
|
|
|
|
CP0552079
|
3-[(1S,5R,9R)-9-(3-hydroxypropyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-5-yl]phenol
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|
C25H33NO2
|
2
|
| 1 |
EC50 = 1.2 nM
|
|
|
| 2 |
EC50 > 25000 nM
|
|
|
|
CP0444864
|
methyl (2S,4aR,6aR,7R,10aR,10bR)-9-benzoyloxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C28H28O8
|
2
|
| 1 |
EC50 = 1.2 nM
|
|
|
| 2 |
EC50 = 140 nM
|
|
|
|
CP0542610
|
4-benzyl-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C24H30N2O2
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0479294
|
3-[(1S,5R,9R)-9-[(E)-3-hydroxyprop-1-enyl]-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-5-yl]phenol
Show/Hide
|
C25H31NO2
|
2
|
| 1 |
EC50 = 2.31 nM
|
|
|
| 2 |
EC50 > 25000 nM
|
|
|
|
CP0868434
|
trans-6'-Fluoro-4',9'-dihydro-N-methyl-4-phenyl-spiro[cyclohexane-1,1'(3'H)-pyrano[3,4-b]indol]-4-amine Hemicitrate
Show/Hide
|
C29H33FN2O8
|
2
|
| 1 |
EC50 = 2.6 nM
|
|
|
| 2 |
Ki = 2 nM
|
|
|
|
CP0553129
|
[(2S,4aR,6aR,7R,9S,10aR,10bR)-9-benzamido-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromen-7-yl] acetate
Show/Hide
|
C28H31NO7
|
2
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
EC50 = 560 nM
|
|
|
|
CP0518437
|
4-(2-fluorophenyl)-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H27FN2O2
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
Ki = 8 nM
|
|
|
|
CP0518458
|
9-[2-(2-fluorophenyl)ethyl]-2-methyl-4-phenyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H27FN2O2
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
Ki = 6 nM
|
|
|
|
CP0533222
|
2,2-dimethyl-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C24H30N2O2
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
Ki = 3 nM
|
|
|
|
CP0496460
|
N-[[4-(4-benzylpiperazin-1-yl)thian-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C26H33F3N4OS
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0563730
|
methyl 1-oxido-1-(2-phenylethyl)-4-(N-propanoylanilino)piperidin-1-ium-4-carboxylate
Show/Hide
|
C24H30N2O4
|
1
|
| 1 |
EC50 = 4.4 nM
|
|
|
|
CP0000305
|
(-)-(etorphine)
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|
C17H19NO3
|
6
|
| 1 |
EC50 = 4.7 nM
|
|
|
| 2 |
EC50 = 5 nM
|
|
|
| 3 |
EC50 = 10 nM
|
|
|
| 4 |
EC50 = 379.6 nM
|
|
|
| 5 |
EC50 = 380 nM
|
|
|
| 6 |
Ki = 5.2 nM
|
|
|
|
CP0444833
|
[(2S,4aR,6aR,7R,10aR,10bR)-7-acetyloxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromen-9-yl] 3-fluorobenzoate
Show/Hide
|
C28H27FO8
|
2
|
| 1 |
EC50 = 4.7 nM
|
|
|
| 2 |
EC50 = 41 nM
|
|
|
|
CP0444863
|
methyl (2S,4aR,6aR,7R,10aR,10bR)-9-(2-fluorobenzoyl)oxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C28H27FO8
|
2
|
| 1 |
EC50 = 4.8 nM
|
|
|
| 2 |
EC50 = 63 nM
|
|
|
|
CP0549544
|
N-[[4-(4-benzylpiperazin-1-yl)-2,2-dimethyloxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C28H37F3N4O2
|
1
|
| 1 |
EC50 = 6 nM
|
|
|
|
CP0568736
|
N-[[1-(4-benzylpiperazin-1-yl)cyclopropyl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
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|
C24H29F3N4O
|
1
|
| 1 |
EC50 = 6 nM
|
|
|
|
CP0535146
|
(2R)-4-cyclopropyl-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
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|
C20H28N2O2
|
1
|
| 1 |
EC50 = 7 nM
|
|
|
|
CP0567567
|
N-benzyl-N-[1-(2-phenylethyl)piperidin-4-yl]furan-2-carboxamide
Show/Hide
|
C25H28N2O2
|
1
|
| 1 |
EC50 = 7.24 nM
|
|
|
|
CP0451330
|
methyl (2S,4aR,6aR,7R,10aR,10bR)-2-(furan-3-yl)-9-(4-methoxybenzoyl)oxy-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C29H30O9
|
2
|
| 1 |
EC50 = 8 nM
|
|
|
| 2 |
EC50 = 96 nM
|
|
|
|
CP0549543
|
N-[[4-(4-benzylpiperazin-1-yl)oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C26H33F3N4O2
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0848864
|
3,4-Dichloro-N-[(2-methyl-1,2,3,4-tetrahydro-1-isoquinolinyl)methyl]benzamide
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|
C18H18Cl2N2O
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0861339
|
4-Ethyl-N-[(2-methyl-1,2,3,4-tetrahydro-1-isoquinolinyl)methyl]benzamide
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0868761
|
3,4-Dimethyl-N-[(2-methyl-1,2,3,4-tetrahydro-1-isoquinolinyl)methyl]benzamide
Show/Hide
|
C20H24N2O
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0426240
|
(2R)-9-[2-(2,3-difluorophenyl)ethyl]-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C19H26F2N2O2
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0444474
|
12-phenyl-8-(2-phenylethyl)-4-oxa-8,12-diazadispiro[2.1.55.33]tridecan-13-one
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|
C24H28N2O2
|
2
|
| 1 |
EC50 = 11 nM
|
|
|
| 2 |
Ki = 15 nM
|
|
|
|
CP0444865
|
methyl (2S,4aR,6aR,7R,10aR,10bR)-2-(furan-3-yl)-9-(3-methoxybenzoyl)oxy-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C29H30O9
|
2
|
| 1 |
EC50 = 11 nM
|
|
|
| 2 |
EC50 = 190 nM
|
|
|
|
CP0572665
|
N-[[1-(4-benzylpiperazin-1-yl)cyclopropyl]methyl]-N-(3-fluorophenyl)propanamide
Show/Hide
|
C24H30FN3O
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0476468
|
9-[2-(3-fluorophenyl)ethyl]-2-methyl-4-phenyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H27FN2O2
|
2
|
| 1 |
EC50 = 13 nM
|
|
|
| 2 |
Ki = 10 nM
|
|
|
|
CP0435812
|
2-methyl-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H28N2O2
|
2
|
| 1 |
EC50 = 14 nM
|
|
|
| 2 |
Ki = 7 nM
|
|
|
|
CP0444862
|
methyl (2S,4aR,6aR,7R,10aR,10bR)-9-(4-fluorobenzoyl)oxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C28H27FO8
|
2
|
| 1 |
EC50 = 15 nM
|
|
|
| 2 |
EC50 = 200 nM
|
|
|
|
CP0353915
|
5,6-dichloro-3-[1-[(4-chlorophenyl)methyl]piperidin-4-yl]-1H-benzimidazol-2-one
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|
C19H18Cl3N3O
|
2
|
| 1 |
EC50 = 15.6 nM
|
|
|
| 2 |
EC50 = 2975 nM
|
|
|
|
CP0518439
|
(2R)-2-methyl-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H28N2O2
|
2
|
| 1 |
EC50 = 16 nM
|
|
|
| 2 |
Ki = 8 nM
|
|
|
|
CP0496395
|
(2R)-9-[2-(2,6-difluorophenyl)ethyl]-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C19H26F2N2O2
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0125925
|
OXYCODONE
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|
C18H21NO4
|
2
|
| 1 |
EC50 = 17 nM
|
|
|
| 2 |
Ki = 12 nM
|
|
|
|
CP0561532
|
methyl 4-(N-propanoylanilino)piperidine-4-carboxylate
Show/Hide
|
C16H22N2O3
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0539898
|
2-methyl-9-(2-phenylethyl)-4-propan-2-yl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C20H30N2O2
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
|
CP0486292
|
2-methyl-4,9-bis(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C25H32N2O2
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
|
CP0444832
|
methyl (2S,4aR,6aR,7R,10aR,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-9-(4-methylbenzoyl)oxy-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C29H30O8
|
2
|
| 1 |
EC50 = 22 nM
|
|
|
| 2 |
EC50 = 360 nM
|
|
|
|
CP0401390
|
1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3S)-3-piperidinyl]-1H-benzimidazole
Show/Hide
|
C26H40N4
|
2
|
| 1 |
EC50 = 23 nM
|
|
|
| 2 |
Ki = 0.59 nM
|
|
|
|
CP0527836
|
(2R)-4-ethyl-9-[2-(2-fluorophenyl)ethyl]-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C19H27FN2O2
|
1
|
| 1 |
EC50 = 24 nM
|
|
|
|
CP0574138
|
N-[[1-(4-benzylpiperazin-1-yl)cyclopropyl]methyl]-N-(3-fluoropyridin-2-yl)propanamide
Show/Hide
|
C23H29FN4O
|
1
|
| 1 |
EC50 = 24 nM
|
|
|
|
CP0435805
|
2-methyl-9-(2-phenylethyl)-4-[4-(trifluoromethyl)pyridin-3-yl]-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H26F3N3O2
|
2
|
| 1 |
EC50 = 25 nM
|
|
|
| 2 |
Ki = 28 nM
|
|
|
|
CP0444498
|
9-[2-(4-fluorophenyl)ethyl]-2-methyl-4-phenyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H27FN2O2
|
2
|
| 1 |
EC50 = 25 nM
|
|
|
| 2 |
Ki = 19 nM
|
|
|
|
CP0482375
|
(2R)-9-[2-(2-fluorophenyl)ethyl]-2-methyl-4-[4-(trifluoromethyl)pyridin-3-yl]-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H25F4N3O2
|
2
|
| 1 |
EC50 = 26 nM
|
|
|
| 2 |
Ki = 11 nM
|
|
|
|
CP0568737
|
N-[[4-(4-benzylpiperazin-1-yl)oxan-4-yl]methyl]-N-phenylpropanamide
Show/Hide
|
C26H35N3O2
|
1
|
| 1 |
EC50 = 26 nM
|
|
|
|
CP0549537
|
N-[[1-(4-benzylpiperazin-1-yl)cyclopropyl]methyl]-N-[3-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C24H29F3N4O
|
1
|
| 1 |
EC50 = 28 nM
|
|
|
|
CP0866024
|
N-{[2-(2-Chloroethyl)-1,2,3,4-tetrahydro-1-isoquinolinyl]methyl}-4-methylbenzamide
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C20H23ClN2O
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1
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| 1 |
EC50 = 30 nM
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CP0444846
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methyl (2S,4aR,6aR,7R,10aR,10bR)-9-(4-chlorobenzoyl)oxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
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C28H27ClO8
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2
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| 1 |
EC50 = 30 nM
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| 2 |
EC50 = 180 nM
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CP0496459
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N-[[4-[4-[2-(2-methylpropoxy)ethyl]piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
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C25H39F3N4O3
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1
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| 1 |
EC50 = 30 nM
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CP0444834
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methyl (2S,4aR,6aR,7R,10aR,10bR)-2-(furan-3-yl)-6a,10b-dimethyl-9-(4-nitrobenzoyl)oxy-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
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C28H27NO10
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2
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| 1 |
EC50 = 31 nM
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| 2 |
EC50 = 330 nM
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CP0552078
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methyl 3-[(1R,5S,9S)-5-(3-hydroxyphenyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-9-yl]propanoate
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C26H33NO3
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2
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| 1 |
EC50 = 31.3 nM
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| 2 |
EC50 > 25000 nM
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CP0552043
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3-[(1S,5R,9R)-5-(3-hydroxyphenyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-9-yl]propanoic acid
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C25H31NO3
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2
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| 1 |
EC50 = 31.7 nM
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| 2 |
EC50 > 25000 nM
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CP0482317
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2-(methoxymethyl)-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
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C24H30N2O3
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2
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| 1 |
EC50 = 32 nM
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| 2 |
Ki = 13 nM
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CP0386129
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1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole
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C26H40N4
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2
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| 1 |
EC50 = 34 nM
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| 2 |
Ki = 1.052 nM
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CP0573260
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N-[[1-(4-benzylpiperazin-1-yl)cyclopropyl]methyl]-N-phenylpropanamide
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C24H31N3O
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1
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| 1 |
EC50 = 34 nM
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CP0549542
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N-[[1-(4-benzylpiperazin-1-yl)cyclopropyl]methyl]-N-(2-hydroxyphenyl)propanamide
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C24H31N3O2
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1
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| 1 |
EC50 = 35 nM
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CP0552077
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3-[(1R,5S,9S)-9-(3-hydroxypropyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-5-yl]phenol
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C25H33NO2
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2
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| 1 |
EC50 = 35.2 nM
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| 2 |
EC50 > 25000 nM
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CP0568690
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N-[[1-(4-benzylpiperazin-1-yl)cyclopropyl]methyl]-N-pyridin-2-ylpropanamide
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C23H30N4O
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1
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| 1 |
EC50 = 39 nM
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CP0858938
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4-Methyl-N-[(2-methyl-1,2,3,4-tetrahydro-1-isoquinolinyl)methyl]benzamide
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C19H22N2O
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1
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| 1 |
EC50 = 40 nM
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CP0036846
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(3S,4aR,4bS,6S,8R,8aR,10aR)-6-Benzoyloxy-3-furan-3-yl-4a,8a-dimethyl-1,5-dioxo-dodecahydro-2-oxa-phenanthrene-8-carboxylic acid methyl ester
Show/Hide
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C28H30O8
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2
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| 1 |
EC50 = 40 nM
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| 2 |
EC50 = 3400 nM
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CP0396908
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1-(2-bromo-4-chlorophenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one
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C16H16BrClN2O
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1
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| 1 |
EC50 = 41 nM
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CP0396914
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1-(2,4-dibromophenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one
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C16H16Br2N2O
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1
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| 1 |
EC50 = 41 nM
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CP0553464
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1-(2-bromo-4-methylphenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one
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C17H19BrN2O
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1
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| 1 |
EC50 = 41 nM
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CP0273301
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N-[(3-fluorophenyl)methyl]-N-[1-(2-phenylethyl)piperidin-4-yl]furan-2-carboxamide
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C25H27FN2O2
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1
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| 1 |
EC50 = 48.5 nM
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CP0539842
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(2R)-4-ethyl-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
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C19H28N2O2
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1
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| 1 |
EC50 = 49 nM
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CP0252205
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(2R)-9-[2-(2,5-difluorophenyl)ethyl]-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
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C19H26F2N2O2
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1
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| 1 |
EC50 = 52 nM
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CP0426239
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(2R)-9-[2-(2,4-difluorophenyl)ethyl]-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
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C19H26F2N2O2
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1
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| 1 |
EC50 = 53 nM
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CP0574140
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N-[[4-[4-(2-propan-2-yloxyethyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
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C24H37F3N4O3
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1
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| 1 |
EC50 = 53 nM
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CP0527835
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(2R)-4-ethyl-9-[2-(3-fluorophenyl)ethyl]-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
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C19H27FN2O2
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1
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| 1 |
EC50 = 56 nM
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CP0396815
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1-[(2S)-2-(dimethylamino)-3-(4-hydroxyphenyl)propyl]-3-[(2S)-1-thiophen-3-ylpropan-2-yl]urea
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C19H27N3O2S
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1
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| 1 |
EC50 = 57.1 nM
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CP0910261
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4-Ethyl-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamide
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C19H22N2O
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1
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| 1 |
EC50 = 60 nM
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CP0482315
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3-[2-(2-methyl-3-oxo-4-phenyl-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl)ethyl]benzonitrile
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C24H27N3O2
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2
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| 1 |
EC50 = 61 nM
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| 2 |
Ki = 49 nM
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CP0476470
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(2R)-9-[2-(2-fluorophenyl)ethyl]-2-methyl-4-[3-(trifluoromethyl)pyridin-2-yl]-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
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C23H25F4N3O2
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2
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| 1 |
EC50 = 65 nM
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| 2 |
Ki = 34 nM
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CP0530023
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4-ethyl-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
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C19H28N2O2
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1
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| 1 |
EC50 = 65 nM
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CP0386132
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1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-1-methyl-3-piperidinyl]-1H-benzimidazole
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C27H42N4
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2
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| 1 |
EC50 = 67 nM
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| 2 |
Ki = 3.7 nM
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CP0444499
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N-[3-[2-[(2R)-2-methyl-3-oxo-4-phenyl-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl]ethyl]phenyl]acetamide
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C25H31N3O3
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2
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| 1 |
EC50 = 69 nM
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| 2 |
Ki = 46 nM
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CP0401391
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1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3S)-1-methyl-3-piperidinyl]-1H-benzimidazole
Show/Hide
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C27H42N4
|
2
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| 1 |
EC50 = 71 nM
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| 2 |
Ki = 11 nM
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CP0549547
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N-[[1-(4-benzylpiperazin-1-yl)cyclopropyl]methyl]-N-(2-fluorophenyl)propanamide
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C24H30FN3O
|
1
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| 1 |
EC50 = 73 nM
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CP0549545
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N-[[4-(1-benzylpiperidin-4-yl)oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
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C27H34F3N3O2
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1
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| 1 |
EC50 = 84 nM
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CP0496456
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N-[[4-[4-(2-propoxyethyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
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C24H37F3N4O3
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1
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| 1 |
EC50 = 86 nM
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CP0396913
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1-(2,4-dibromophenyl)-3,6,6-trimethyl-5,7-dihydro-4H-indazol-4-ol
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C16H18Br2N2O
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1
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| 1 |
EC50 = 100 nM
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CP0435813
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4-phenyl-9-(2-phenylethyl)-2-(phenylmethoxymethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
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C30H34N2O3
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2
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| 1 |
EC50 = 107 nM
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| 2 |
Ki = 40 nM
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CP0426236
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(2R)-4-ethyl-9-[2-(4-fluorophenyl)ethyl]-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
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C19H27FN2O2
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1
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| 1 |
EC50 = 108 nM
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CP0893657
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4-Methyl-N-{[2-(2-methylpropyl)-1,2,3,4-tetrahydro-1-isoquinolinyl]methyl}benzamide
Show/Hide
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C22H28N2O
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1
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| 1 |
EC50 = 110 nM
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CP0861340
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3,4-Dimethyl-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamide
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C19H22N2O
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1
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| 1 |
EC50 = 120 nM
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CP0273298
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N-[(4-fluorophenyl)methyl]-N-[1-(2-phenylethyl)piperidin-4-yl]butanamide
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C24H31FN2O
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1
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| 1 |
EC50 = 121.8 nM
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CP0533224
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2-(hydroxymethyl)-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
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C23H28N2O3
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2
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| 1 |
EC50 = 125 nM
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| 2 |
Ki = 46 nM
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CP0479296
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methyl (E)-3-[(1S,5R,9R)-5-(3-hydroxyphenyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-9-yl]prop-2-enoate
Show/Hide
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C26H31NO3
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2
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| 1 |
EC50 = 132 nM
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| 2 |
EC50 > 25000 nM
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CP0496461
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N-[[4-[4-(2-phenoxyethyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
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C27H35F3N4O3
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1
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| 1 |
EC50 = 133 nM
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CP0946940
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4-Methyl-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamide
Show/Hide
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C18H20N2O
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1
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| 1 |
EC50 = 140 nM
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CP0569288
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N-[[4-[4-(1-phenylethyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
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C27H35F3N4O2
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1
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| 1 |
EC50 = 142 nM
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CP0427455
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1-{1-[1-(Hydroxymethyl)cyclooctyl]piperidin-4-yl}-1Hbenzimidazol-2(3H)-one
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C21H31N3O2
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2
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| 1 |
EC50 = 144 nM
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| 2 |
Ki = 16 nM
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CP0538317
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4-(2-methoxyphenyl)-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
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C24H30N2O3
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2
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| 1 |
EC50 = 144 nM
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| 2 |
Ki = 57 nM
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CP0396910
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1-(2,4-dichlorophenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one
Show/Hide
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C16H16Cl2N2O
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1
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| 1 |
EC50 = 150 nM
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CP0574198
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N-[[1-(4-benzylpiperazin-1-yl)cyclohexyl]methyl]-N-phenylpropanamide
Show/Hide
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C27H37N3O
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1
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| 1 |
EC50 = 158 nM
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CP0861341
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N-[(2-Butyl-1,2,3,4-tetrahydro-1-isoquinolinyl)methyl]-4-methylbenzamide
Show/Hide
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C22H28N2O
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1
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| 1 |
EC50 = 160 nM
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CP0533168
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4-methyl-9-(2-phenylethyl)-2-propan-2-yl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C20H30N2O2
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1
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| 1 |
EC50 = 174 nM
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CP0570045
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N-[[4-(4-propylpiperazin-1-yl)oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
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C22H33F3N4O2
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1
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| 1 |
EC50 = 180 nM
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CP0435808
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methyl 2-[3-oxo-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-2-yl]acetate
Show/Hide
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C25H30N2O4
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2
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| 1 |
EC50 = 181 nM
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| 2 |
Ki = 92 nM
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CP0496458
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N-[[4-[4-(2-methylpropyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C23H35F3N4O2
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1
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| 1 |
EC50 = 183 nM
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CP0435810
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2-methyl-9-(2-phenylethyl)-4-[2-(trifluoromethyl)pyridin-3-yl]-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
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C23H26F3N3O2
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2
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| 1 |
EC50 = 186 nM
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| 2 |
Ki = 123 nM
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CP0372877
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2-(3,5-dimethylpiperazin-1-yl)-1-[1-(1-methylcyclooctyl)piperidin-4-yl]-1H-benzimidazole
Show/Hide
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C27H43N5
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2
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| 1 |
EC50 = 193 nM
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| 2 |
Ki = 21 nM
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CP0324869
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8-[2-(2-fluorophenyl)ethyl]-12-[2-(trifluoromethyl)pyridin-3-yl]-4-oxa-8,12-diazadispiro[2.1.55.33]tridecan-13-one
Show/Hide
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C24H25F4N3O2
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2
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| 1 |
EC50 = 195 nM
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| 2 |
Ki = 175 nM
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CP0444844
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4-(3-fluoropyridin-2-yl)-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C22H26FN3O2
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2
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| 1 |
EC50 = 199 nM
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| 2 |
Ki = 93 nM
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CP0549546
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N-[[4-[4-(2-ethoxyethyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C23H35F3N4O3
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1
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| 1 |
EC50 = 210 nM
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CP0476467
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2-methyl-9-(2-phenylethyl)-4-[6-(trifluoromethyl)pyridin-2-yl]-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H26F3N3O2
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2
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| 1 |
EC50 = 219 nM
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| 2 |
Ki = 90 nM
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CP0435818
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2-methyl-4-phenyl-9-(2-pyridin-2-ylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C22H27N3O2
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2
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| 1 |
EC50 = 229 nM
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| 2 |
Ki = 90 nM
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CP0848863
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4-Chloro-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamide
Show/Hide
|
C17H17ClN2O
|
1
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| 1 |
EC50 = 230 nM
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CP0482314
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4-(5-fluoropyridin-3-yl)-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C22H26FN3O2
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2
|
| 1 |
EC50 = 230 nM
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| 2 |
Ki = 204 nM
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CP0564502
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N-[(4-fluorophenyl)methyl]-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
Show/Hide
|
C23H29FN2O
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1
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| 1 |
EC50 = 231.3 nM
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CP0893658
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3,4-Dichloro-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamide
Show/Hide
|
C17H16Cl2N2O
|
1
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| 1 |
EC50 = 250 nM
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CP0698743
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N-[(1S,2S)-1-[2-(dimethylamino)ethylcarbamoyl]indan-2-yl]-5-methyl-1H-indole-2-carboxamide
Show/Hide
|
C24H28N4O2
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2
|
| 1 |
EC50 = 251.19 nM
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| 2 |
IC50 > 100000 nM
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CP0549548
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N-[[3-(4-benzylpiperazin-1-yl)oxetan-3-yl]methyl]-N-phenylpropanamide
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
EC50 = 253 nM
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CP0444838
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(2S)-2-methyl-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H28N2O2
|
2
|
| 1 |
EC50 = 264 nM
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| 2 |
Ki = 69 nM
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CP0372874
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1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-2-[3-(methylsulfonyl)phenyl]-1H-benzimidazole
Show/Hide
|
C28H37N3O2S
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2
|
| 1 |
EC50 = 288 nM
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| 2 |
Ki = 6.3 nM
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CP0572662
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N-[2-(4-benzylpiperazin-1-yl)-2-methylpropyl]-N-phenylpropanamide
Show/Hide
|
C24H33N3O
|
1
|
| 1 |
EC50 = 299 nM
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CP0435815
|
4-(3-methoxyphenyl)-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C24H30N2O3
|
2
|
| 1 |
EC50 = 304 nM
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| 2 |
Ki = 126 nM
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|
|
CP0496462
|
N-[[4-[4-[2-(2,2,2-trifluoroethoxy)ethyl]piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C23H32F6N4O3
|
1
|
| 1 |
EC50 = 314 nM
|
|
|
|
CP0426234
|
(2R)-2,4-dimethyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C18H26N2O2
|
1
|
| 1 |
EC50 = 319 nM
|
|
|
|
CP0372876
|
1-(3-{1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-1H-benzimidazol-2-yl}phenyl)methanamine
Show/Hide
|
C28H38N4
|
2
|
| 1 |
EC50 = 340 nM
|
|
|
| 2 |
Ki = 20 nM
|
|
|
|
CP0534336
|
N-[2-[2-(2-methyl-3-oxo-4-phenyl-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl)ethyl]phenyl]acetamide
Show/Hide
|
C25H31N3O3
|
2
|
| 1 |
EC50 = 342 nM
|
|
|
| 2 |
Ki = 190 nM
|
|
|
|
CP0435816
|
2-methyl-9-(2-phenylethyl)-4-[3-(trifluoromethyl)pyridin-2-yl]-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H26F3N3O2
|
2
|
| 1 |
EC50 = 343 nM
|
|
|
| 2 |
Ki = 262 nM
|
|
|
|
CP0444476
|
N-[3-[2-(2-methyl-3-oxo-4-phenyl-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl)ethyl]phenyl]acetamide
Show/Hide
|
C25H31N3O3
|
2
|
| 1 |
EC50 = 343 nM
|
|
|
| 2 |
Ki = 144 nM
|
|
|
|
CP0396909
|
3-cyclopropyl-1-(2,4-dichlorophenyl)-6,6-dimethyl-5,7-dihydroindazol-4-one
Show/Hide
|
C18H18Cl2N2O
|
1
|
| 1 |
EC50 = 370 nM
|
|
|
|
CP0530688
|
1-(4-chloro-2-methylphenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one
Show/Hide
|
C17H19ClN2O
|
1
|
| 1 |
EC50 = 370 nM
|
|
|
|
CP0568893
|
1-(2,4-dimethylphenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one
Show/Hide
|
C18H22N2O
|
1
|
| 1 |
EC50 = 370 nM
|
|
|
|
CP0848865
|
N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)-4-(trifluoromethoxy)benzamide
Show/Hide
|
C18H17F3N2O2
|
1
|
| 1 |
EC50 = 370 nM
|
|
|
|
CP0866022
|
4-Methoxy-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamide
Show/Hide
|
C18H20N2O2
|
1
|
| 1 |
EC50 = 370 nM
|
|
|
|
CP0906414
|
3-Methyl-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamide
Show/Hide
|
C18H20N2O
|
1
|
| 1 |
EC50 = 370 nM
|
|
|
|
CP0861342
|
3-Chloro-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamide
Show/Hide
|
C17H17ClN2O
|
1
|
| 1 |
EC50 = 380 nM
|
|
|
|
CP0558729
|
12-methyl-8-(2-phenylethyl)-4-oxa-8,12-diazadispiro[2.1.55.33]tridecan-13-one
Show/Hide
|
C19H26N2O2
|
1
|
| 1 |
EC50 = 442 nM
|
|
|
|
CP0552477
|
(2R)-2-ethyl-4-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C19H28N2O2
|
1
|
| 1 |
EC50 = 505 nM
|
|
|
|
CP0549549
|
N-[[4-(4-butylpiperazin-1-yl)oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C23H35F3N4O2
|
1
|
| 1 |
EC50 = 510 nM
|
|
|
|
CP0573298
|
N-[2-(4-benzylpiperazin-1-yl)ethyl]-N-phenylpropanamide
Show/Hide
|
C22H29N3O
|
1
|
| 1 |
EC50 = 515 nM
|
|
|
|
CP0538320
|
4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C22H26N2O2
|
2
|
| 1 |
EC50 = 523 nM
|
|
|
| 2 |
Ki = 437 nM
|
|
|
|
CP0482313
|
2-methyl-9-(2-phenylethyl)-4-pyrazin-2-yl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C21H26N4O2
|
2
|
| 1 |
EC50 = 527 nM
|
|
|
| 2 |
Ki = 304 nM
|
|
|
|
CP0866030
|
4-Fluoro-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamide
Show/Hide
|
C17H17FN2O
|
1
|
| 1 |
EC50 = 540 nM
|
|
|
|
CP0496455
|
ethyl 3-[4-[4-[[propanoyl-[6-(trifluoromethyl)pyridin-2-yl]amino]methyl]oxan-4-yl]piperazin-1-yl]propanoate
Show/Hide
|
C24H35F3N4O4
|
1
|
| 1 |
EC50 = 598 nM
|
|
|
|
CP0491948
|
2,2,4-trimethyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C19H28N2O2
|
1
|
| 1 |
EC50 = 624 nM
|
|
|
|
CP0533223
|
2-methyl-9-(2-phenylethyl)-4-pyridin-3-yl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C22H27N3O2
|
2
|
| 1 |
EC50 = 627 nM
|
|
|
| 2 |
Ki = 304 nM
|
|
|
|
CP0946939
|
2,4-Dimethyl-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamide
Show/Hide
|
C19H22N2O
|
1
|
| 1 |
EC50 = 660 nM
|
|
|
|
CP0549540
|
N-[[4-[4-(2-methoxyethyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C22H33F3N4O3
|
1
|
| 1 |
EC50 = 720 nM
|
|
|
|
CP0435811
|
2-methyl-9-(2-phenylethyl)-4-[5-(trifluoromethyl)pyridin-3-yl]-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H26F3N3O2
|
2
|
| 1 |
EC50 = 721 nM
|
|
|
| 2 |
Ki = 261 nM
|
|
|
|
CP0569685
|
N-[[4-(4-benzylpiperazin-1-yl)-1-methylpiperidin-4-yl]methyl]-N-phenylpropanamide
Show/Hide
|
C27H38N4O
|
1
|
| 1 |
EC50 = 738 nM
|
|
|
|
CP0909508
|
N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamide
Show/Hide
|
C17H18N2O
|
1
|
| 1 |
EC50 = 750 nM
|
|
|
|
CP0386131
|
2-(3-Chloro-4-fluorophenyl)-1-[1-(1-methylcyclooctyl)piperidin-4-yl]-1H-benzimidazole
Show/Hide
|
C27H33ClFN3
|
2
|
| 1 |
EC50 = 759 nM
|
|
|
| 2 |
Ki = 45 nM
|
|
|
|
CP0482374
|
2-methyl-9-(2-pyridin-2-ylethyl)-4-[4-(trifluoromethyl)pyridin-3-yl]-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C22H25F3N4O2
|
2
|
| 1 |
EC50 = 767 nM
|
|
|
| 2 |
Ki = 127 nM
|
|
|
|
CP0910260
|
3-Fluoro-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamide
Show/Hide
|
C17H17FN2O
|
1
|
| 1 |
EC50 = 780 nM
|
|
|
|
CP0472861
|
2,4-dimethyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C18H26N2O2
|
1
|
| 1 |
EC50 = 787 nM
|
|
|
|
CP0518443
|
2-methyl-4-phenyl-9-(2-pyridin-3-ylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C22H27N3O2
|
2
|
| 1 |
EC50 = 853 nM
|
|
|
| 2 |
Ki = 117 nM
|
|
|
|
CP0479298
|
methyl 3-[(1S,5R,9S)-5-(3-hydroxyphenyl)-2-(2-phenylethyl)-2-azabicyclo[3.3.1]nonan-9-yl]propanoate
Show/Hide
|
C26H33NO3
|
2
|
| 1 |
EC50 = 854 nM
|
|
|
| 2 |
EC50 > 25000 nM
|
|
|
|
CP0959548
|
3-Methoxy-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamide
Show/Hide
|
C18H20N2O2
|
1
|
| 1 |
EC50 = 860 nM
|
|
|
|
CP0496463
|
N-[[4-[4-(2-hydroxy-2-methylpropyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C23H35F3N4O3
|
1
|
| 1 |
EC50 = 869 nM
|
|
|
|
CP0426235
|
(2S)-9-[2-(2,5-difluorophenyl)ethyl]-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C19H26F2N2O2
|
1
|
| 1 |
EC50 = 910 nM
|
|
|
|
CP0549538
|
N-[[4-[4-(2-hydroxy-1-phenylethyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C27H35F3N4O3
|
1
|
| 1 |
EC50 = 972 nM
|
|
|
|
CP0868687
|
trans-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-4-amine 2-hydroxypropane-1,2,3-tricarboxylate
Show/Hide
|
C30H36N2O8
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0568894
|
1-(2-bromophenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one
Show/Hide
|
C16H17BrN2O
|
1
|
| 1 |
EC50 = 1120 nM
|
|
|
|
CP0893654
|
4-Ethyl-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)cyclohexanecarboxamide
Show/Hide
|
C19H28N2O
|
1
|
| 1 |
EC50 = 1120 nM
|
|
|
|
CP0909506
|
N-({2-[(4-Bromo-2-trifluoromethoxyphenyl)sulfonyl]-1,2,3,4-tetrahydro-1-isoquinolinyl}methyl)cyclohexanecarboxamide
Show/Hide
|
C24H26BrF3N2O4S
|
1
|
| 1 |
EC50 = 1120 nM
|
|
|
|
CP0496457
|
N-[[1-(4-methylpiperazin-1-yl)cyclohexyl]methyl]-2,2-diphenylpropanamide
Show/Hide
|
C27H37N3O
|
1
|
| 1 |
EC50 = 1167 nM
|
|
|
|
CP0376885
|
(1-{4-[2-(3-Chloro-4-fluorophenyl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclooctyl)methanol
Show/Hide
|
C27H33ClFN3O
|
2
|
| 1 |
EC50 = 1219 nM
|
|
|
| 2 |
Ki = 302 nM
|
|
|
|
CP0496454
|
N-[(4-piperazin-1-yloxan-4-yl)methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C19H27F3N4O2
|
1
|
| 1 |
EC50 = 1237 nM
|
|
|
|
CP0518442
|
2-methyl-4-phenyl-9-(2-pyridin-4-ylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C22H27N3O2
|
2
|
| 1 |
EC50 = 1424 nM
|
|
|
| 2 |
Ki = 516 nM
|
|
|
|
CP0576651
|
N-[2-(4-benzylpiperazin-1-yl)-2-methylpropyl]-2-methoxy-N-phenylacetamide
Show/Hide
|
C24H33N3O2
|
1
|
| 1 |
EC50 = 1468 nM
|
|
|
|
CP0552933
|
12-ethyl-8-(2-pyridin-2-ylethyl)-4-oxa-8,12-diazadispiro[2.1.55.33]tridecan-13-one
Show/Hide
|
C19H27N3O2
|
1
|
| 1 |
EC50 = 1498 nM
|
|
|
|
CP0910258
|
4-Methyl-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)cyclohexanecarboxamide
Show/Hide
|
C18H26N2O
|
1
|
| 1 |
EC50 = 1530 nM
|
|
|
|
CP0553467
|
1-(2,4-dichlorophenyl)-6,6-dimethyl-3-(trifluoromethyl)-5,7-dihydroindazol-4-one
Show/Hide
|
C16H13Cl2F3N2O
|
1
|
| 1 |
EC50 = 1540 nM
|
|
|
|
CP0377808
|
(1-{4-[2-(3-Methylpiperazin-1-yl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclooctyl)methanol
Show/Hide
|
C26H41N5O
|
2
|
| 1 |
EC50 = 1772 nM
|
|
|
| 2 |
Ki > 450 nM
|
|
|
|
CP0426270
|
(2S)-2,4-dimethyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C18H26N2O2
|
1
|
| 1 |
EC50 = 1780 nM
|
|
|
|
CP0444842
|
2-methyl-9-(2-phenylethyl)-4-pyridin-2-yl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C22H27N3O2
|
2
|
| 1 |
EC50 = 1987 nM
|
|
|
| 2 |
Ki = 930 nM
|
|
|
|
CP0426637
|
1-(2-chlorophenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one
Show/Hide
|
C16H17ClN2O
|
1
|
| 1 |
EC50 = 2280 nM
|
|
|
|
CP0549567
|
4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(2-ethyl-6-methylphenyl)-1,3-thiazol-2-amine
Show/Hide
|
C17H19N3S2
|
1
|
| 1 |
EC50 = 2800 nM
|
|
|
|
CP0483742
|
1-(2,5-dichlorophenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one
Show/Hide
|
C16H16Cl2N2O
|
1
|
| 1 |
EC50 = 2890 nM
|
|
|
|
CP0435804
|
9-benzyl-4-phenyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C21H24N2O2
|
2
|
| 1 |
EC50 = 3044 nM
|
|
|
| 2 |
Ki = 534 nM
|
|
|
|
CP0893656
|
2-Fluoro-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamide
Show/Hide
|
C17H17FN2O
|
1
|
| 1 |
EC50 = 3280 nM
|
|
|
|
CP0536348
|
4-(2,4-dimethyl-1,3-oxazol-5-yl)-N-(2-ethylphenyl)-1,3-thiazol-2-amine
Show/Hide
|
C16H17N3OS
|
1
|
| 1 |
EC50 = 3300 nM
|
|
|
|
CP0549565
|
4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(3-methoxy-2-methylphenyl)-1,3-thiazol-2-amine
Show/Hide
|
C16H17N3OS2
|
1
|
| 1 |
EC50 = 3300 nM
|
|
|
|
CP0861360
|
2-Methoxy-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamide
Show/Hide
|
C18H20N2O2
|
1
|
| 1 |
EC50 = 3310 nM
|
|
|
|
CP0953483
|
N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)-2-(trifluoromethoxy)benzamide
Show/Hide
|
C18H17F3N2O2
|
1
|
| 1 |
EC50 = 3310 nM
|
|
|
|
CP0962259
|
N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)-1-piperidinecarboxamide
Show/Hide
|
C16H23N3O
|
1
|
| 1 |
EC50 = 3310 nM
|
|
|
|
CP0145209
|
[1-[4-[2-(2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl)benzimidazol-1-yl]piperidin-1-yl]cyclooctyl]methanol
Show/Hide
|
C27H41N5O
|
2
|
| 1 |
EC50 = 3500 nM
|
|
|
| 2 |
Ki = 201 nM
|
|
|
|
CP0443386
|
2-(1-Benzofuran-2-yl)-1-[1-(1-methylcyclooctyl)piperidin-4-yl]-1H-benzimidazole
Show/Hide
|
C29H35N3O
|
2
|
| 1 |
EC50 = 3673 nM
|
|
|
| 2 |
Ki = 102 nM
|
|
|
|
CP0416874
|
4-(2,4-dimethyl-1,3-oxazol-5-yl)-N-(2,4,6-trimethylphenyl)-1,3-thiazol-2-amine
Show/Hide
|
C17H19N3OS
|
1
|
| 1 |
EC50 = 3900 nM
|
|
|
|
CP0416873
|
4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(2-ethylphenyl)-1,3-thiazol-2-amine
Show/Hide
|
C16H17N3S2
|
1
|
| 1 |
EC50 = 4000 nM
|
|
|
|
CP0910259
|
N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)-1-pyrrolidinecarboxamide
Show/Hide
|
C15H21N3O
|
1
|
| 1 |
EC50 = 4020 nM
|
|
|
|
CP0416879
|
4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(2-fluoro-6-methylphenyl)-1,3-thiazol-2-amine
Show/Hide
|
C15H14FN3S2
|
1
|
| 1 |
EC50 = 4200 nM
|
|
|
|
CP0549535
|
N-[[1-(4-methylpiperazin-1-yl)cyclohexyl]methyl]-2-phenoxybenzamide
Show/Hide
|
C25H33N3O2
|
1
|
| 1 |
EC50 = 4527 nM
|
|
|
|
CP0529530
|
3,6,6-trimethyl-1-(2-methylphenyl)-5,7-dihydroindazol-4-one
Show/Hide
|
C17H20N2O
|
1
|
| 1 |
EC50 = 4720 nM
|
|
|
|
CP0416878
|
N-(4-bromo-2-ethylphenyl)-4-(2,4-dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-amine
Show/Hide
|
C16H16BrN3S2
|
1
|
| 1 |
EC50 = 4900 nM
|
|
|
|
CP0416880
|
4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(2,4,6-trimethylphenyl)-1,3-thiazol-2-amine
Show/Hide
|
C17H19N3S2
|
1
|
| 1 |
EC50 = 6100 nM
|
|
|
|
CP0560222
|
N-(1,2,3,4-tetrahydroisoquinolin-1-ylmethyl)cyclohexanecarboxamide
Show/Hide
|
C17H24N2O
|
1
|
| 1 |
EC50 = 6380 nM
|
|
|
|
CP0893655
|
4-Methoxy-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)cyclohexanecarboxamide
Show/Hide
|
C18H26N2O2
|
1
|
| 1 |
EC50 = 6600 nM
|
|
|
|
CP0909507
|
N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)cyclobutanecarboxamide
Show/Hide
|
C15H20N2O
|
1
|
| 1 |
EC50 = 6800 nM
|
|
|
|
CP0954782
|
N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)-4-morpholinecarboxamide
Show/Hide
|
C15H21N3O2
|
1
|
| 1 |
EC50 = 8080 nM
|
|
|
|
CP0530261
|
4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-[2-(2,2,2-trifluoroethyl)phenyl]-1,3-thiazol-2-amine
Show/Hide
|
C16H14F3N3S2
|
1
|
| 1 |
EC50 = 8500 nM
|
|
|
|
CP0536349
|
4-(2-ethyl-4-methyl-1,3-thiazol-5-yl)-N-(2-ethylphenyl)-1,3-thiazol-2-amine
Show/Hide
|
C17H19N3S2
|
1
|
| 1 |
EC50 = 8600 nM
|
|
|
|
CP0443423
|
2-(1H-Indol-6-yl)-1-[1-(1-methylcyclooctyl)piperidin-4-yl]-1Hbenzimidazole
Show/Hide
|
C29H36N4
|
2
|
| 1 |
EC50 = 8625 nM
|
|
|
| 2 |
Ki = 151 nM
|
|
|
|
CP0416875
|
N-(2,4-dimethylphenyl)-4-(2,4-dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-amine
Show/Hide
|
C16H17N3S2
|
1
|
| 1 |
EC50 = 8800 nM
|
|
|
|
CP0400260
|
1-(2,3-dimethylphenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one
Show/Hide
|
C18H22N2O
|
1
|
| 1 |
EC50 = 8900 nM
|
|
|
|
CP0946938
|
N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)cyclopentanecarboxamide
Show/Hide
|
C16H22N2O
|
1
|
| 1 |
EC50 = 8910 nM
|
|
|
|
CP0555738
|
1-(4-bromophenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one
Show/Hide
|
C16H17BrN2O
|
1
|
| 1 |
EC50 = 9910 nM
|
|
|
|
CP0386130
|
1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-2-[3-(trifluoromethyl)phenyl]-1H-benzimidazole
Show/Hide
|
C28H34F3N3
|
2
|
| 1 |
EC50 = 10000 nM
|
|
|
| 2 |
Ki = 65 nM
|
|
|
|
CP0377809
|
(1-{4-[2-(4-Chlorophenyl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclooctyl)methanol
Show/Hide
|
C27H34ClN3O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Ki = 178 nM
|
|
|
|
CP0509128
|
1-(2,5-dimethylphenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one
Show/Hide
|
C18H22N2O
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0509129
|
methyl 4-(3,6,6-trimethyl-4-oxo-5,7-dihydroindazol-1-yl)benzoate
Show/Hide
|
C18H20N2O3
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0866016
|
2-Methyl-N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)cyclohexanecarboxamide
Show/Hide
|
C18H26N2O
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0396496
|
(6R)-6-(2,2-dimethylpropyl)-2-(pyridin-2-ylmethoxy)-7,9-dihydro-6H-pyrimido[2,1-c][1,4]oxazin-4-one
Show/Hide
|
C18H23N3O3
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0008601
|
4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1-(4-fluoro-phenyl)-butan-1-one;propionate(HCl)
Show/Hide
|
C21H23ClFNO2
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0141502
|
4-[2-(5-methyl-1-naphthalen-2-ylpyrazol-3-yl)oxyethyl]morpholine
Show/Hide
|
C20H23N3O2
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Ki > 10000 nM
|
|
|
|
CP0036843
|
(2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(furan-3-yl)dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho-[2,1-c]pyran-7-carboxylic acid methyl ester
Show/Hide
|
C23H28O8
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0280997
|
(2S,4aR,6aR,7R,9R,10aS,10bR)-9-(Acetyloxy)-2-(3-furanyl)-dodecahydro-6a,10b-dimethyl-4,10-dioxo-2H-naphtho[2,1-c]pyran-7-carboxylic acid methyl ester
Show/Hide
|
C23H28O8
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0482740
|
methyl (2S,4aR,6aS,7R,10bS)-2-(furan-3-yl)-10-hydroxy-6a,10b-dimethyl-4,9-dioxo-2,4a,5,6,7,8-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C21H24O7
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0537531
|
methyl (2S,4aR,6aR,7R,10aR,10bR)-2-(furan-3-yl)-9-hydroxy-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C21H24O7
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0553150
|
methyl (2S,4aR,6aR,7R,9R,10aS,10bR)-9-benzoyloxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C28H30O8
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0553151
|
methyl (2S,4aR,6aR,7R,10aR,10bR)-9-acetyloxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,10a-hexahydro-1H-benzo[f]isochromene-7-carboxylate
Show/Hide
|
C23H26O8
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0496451
|
N-[2-(4-benzylpiperazin-1-yl)-2-methylpropyl]aniline
Show/Hide
|
C21H29N3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0496452
|
N-[[1-(4-benzylpiperazin-1-yl)cyclopropyl]methyl]-2-methoxy-N-phenylacetamide
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0496453
|
N-benzyl-N-[[1-(4-benzylpiperazin-1-yl)cyclopropyl]methyl]propanamide
Show/Hide
|
C25H33N3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0549541
|
N-[[1-(4-methylpiperazin-1-yl)cyclohexyl]methyl]-N-phenylpropanamide
Show/Hide
|
C21H33N3O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0568691
|
N-[[4-[4-(3-methoxypropyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C23H35F3N4O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0574190
|
N-[[4-[4-(2-phenylethyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C27H35F3N4O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0530262
|
4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(3-fluoro-2-methylphenyl)-1,3-thiazol-2-amine
Show/Hide
|
C15H14FN3S2
|
1
|
| 1 |
EC50 = 10100 nM
|
|
|
|
CP0537548
|
1-(2,4-difluorophenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one
Show/Hide
|
C16H16F2N2O
|
1
|
| 1 |
EC50 = 10300 nM
|
|
|
|
CP0894726
|
1-((trans)-4-(dimethylamino)-4-phenylcyclohexyl)-3-(3-phenylpropyl)urea hydrochloride
Show/Hide
|
C24H34ClN3O
|
2
|
| 1 |
EC50 = 12000 nM
|
|
|
| 2 |
Ki = 0.7 nM
|
|
|
|
CP0536347
|
5-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(2-ethylphenyl)-1,3-oxazol-2-amine
Show/Hide
|
C16H17N3OS
|
1
|
| 1 |
EC50 = 13300 nM
|
|
|
|
CP0483741
|
1-(2,4-dichlorophenyl)-3-methyl-6,7-dihydro-5H-indazol-4-one
Show/Hide
|
C14H12Cl2N2O
|
1
|
| 1 |
EC50 = 13600 nM
|
|
|
|
CP0509130
|
1-(4-chlorophenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one
Show/Hide
|
C16H17ClN2O
|
1
|
| 1 |
EC50 = 13600 nM
|
|
|
|
CP0478527
|
N-[4-bromo-2-(trifluoromethyl)phenyl]-4-(2,4-dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-amine
Show/Hide
|
C15H11BrF3N3S2
|
1
|
| 1 |
EC50 = 13800 nM
|
|
|
|
CP0470510
|
4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(4-methoxy-2-methylphenyl)-1,3-thiazol-2-amine
Show/Hide
|
C16H17N3OS2
|
1
|
| 1 |
EC50 = 14000 nM
|
|
|
|
CP0568956
|
1-(4-methoxyphenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one
Show/Hide
|
C17H20N2O2
|
1
|
| 1 |
EC50 = 18400 nM
|
|
|
|
CP0400261
|
1-(2-ethylphenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one
Show/Hide
|
C18H22N2O
|
1
|
| 1 |
EC50 = 19000 nM
|
|
|
|
CP0236146
|
N-(2,4-dimethoxyphenyl)-4-(2,4-dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-amine
Show/Hide
|
C16H17N3O2S2
|
1
|
| 1 |
EC50 = 19000 nM
|
|
|
|
CP0339319
|
N-[(3R,4S)-1-(benzenesulfonyl)-4-[[(3S)-piperidin-3-yl]carbamoyl]pyrrolidin-3-yl]-5-(2-chlorophenyl)-1,2-oxazole-3-carboxamide
Show/Hide
|
C26H28ClN5O5S
|
2
|
| 1 |
EC50 = 19952.62 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0139360
|
N-[(3R,4S)-1-(benzenesulfonyl)-4-[[(3S)-piperidin-3-yl]carbamoyl]pyrrolidin-3-yl]-5-phenyl-1,2-oxazole-3-carboxamide
Show/Hide
|
C26H29N5O5S
|
2
|
| 1 |
EC50 = 25118.86 nM
|
|
|
| 2 |
IC50 > 100000 nM
|
|
|
|
CP0416876
|
N-(4-bromo-2-methylphenyl)-4-(2,4-dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-amine
Show/Hide
|
C15H14BrN3S2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0416877
|
5-[2-(2-ethylanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-amine
Show/Hide
|
C15H16N4S2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0469779
|
4-(2,4-dimethyl-1,3-thiazol-5-yl)-1,3-thiazol-2-amine
Show/Hide
|
C8H9N3S2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0469780
|
N-(2-ethylphenyl)-4-methyl-1,3-thiazol-2-amine
Show/Hide
|
C12H14N2S
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0530258
|
4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(2-ethylphenyl)-5-methyl-1,3-thiazol-2-amine
Show/Hide
|
C17H19N3S2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0530259
|
N-(2-ethylphenyl)-4-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-1,3-thiazol-2-amine
Show/Hide
|
C21H19N3S2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0530260
|
N-[5-[2-(2-ethylanilino)-1,3-thiazol-4-yl]-4-methyl-1,3-thiazol-2-yl]acetamide
Show/Hide
|
C17H18N4OS2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0548237
|
N-(2-ethylphenyl)-4-(1,3-thiazol-2-yl)-1,3-thiazol-2-amine
Show/Hide
|
C14H13N3S2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0549566
|
4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-[2,6-di(propan-2-yl)phenyl]-1,3-thiazol-2-amine
Show/Hide
|
C20H25N3S2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0396911
|
ethyl 2-(3,6,6-trimethyl-4-oxo-5,7-dihydroindazol-1-yl)benzoate
Show/Hide
|
C19H22N2O3
|
1
|
| 1 |
EC50 = 30200 nM
|
|
|
|
CP0868689
|
trans-N4-(2-(1H-indol-3-yl)ethyl)-N1,N1-dimethyl-1-phenylcyclohexane-1,4-diamine dihydrochloride
Show/Hide
|
C24H33Cl2N3
|
2
|
| 1 |
EC50 = 51000 nM
|
|
|
| 2 |
Ki = 9.5 nM
|
|
|
|
CP0213288
|
3,6,6-trimethyl-5,7-dihydro-2H-indazol-4-one
Show/Hide
|
C10H14N2O
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0426636
|
3,6,6-trimethyl-1-phenyl-5,7-dihydroindazol-4-one
Show/Hide
|
C16H18N2O
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0509131
|
1-(3-chlorophenyl)-3,6,6-trimethyl-5,7-dihydroindazol-4-one
Show/Hide
|
C16H17ClN2O
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0386133
|
2-(3-{1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-1H-benzimidazol-2-yl}phenoxy)ethanol
Show/Hide
|
C29H39N3O2
|
2
|
| 1 |
EC50 > 393 nM
|
|
|
| 2 |
Ki = 11 nM
|
|
|
|
CP0435807
|
9-phenyl-2-(2-phenylethyl)-6-oxa-2,9-diazaspiro[4.5]decan-8-one
Show/Hide
|
C21H24N2O2
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0435814
|
4-(2-hydroxyphenyl)-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H28N2O3
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
Ki = 535 nM
|
|
|
|
CP0435817
|
2-methyl-9-(2-phenylethyl)-4-[6-(trifluoromethyl)pyridin-3-yl]-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H26F3N3O2
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0444843
|
2-methyl-9-(2-phenylethyl)-4-pyridin-4-yl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C22H27N3O2
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0476469
|
N,N-dimethyl-2-[3-oxo-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-2-yl]acetamide
Show/Hide
|
C26H33N3O3
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
Ki = 636 nM
|
|
|
|
CP0482311
|
N-[4-[2-(2-methyl-3-oxo-4-phenyl-1-oxa-4,9-diazaspiro[5.5]undecan-9-yl)ethyl]phenyl]acetamide
Show/Hide
|
C25H31N3O3
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0482316
|
3-phenyl-8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Show/Hide
|
C21H24N2O2
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
Ki = 401 nM
|
|
|
|
CP0482318
|
2-[3-oxo-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-2-yl]acetic acid
Show/Hide
|
C24H28N2O4
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0518440
|
4-(4-methoxyphenyl)-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C24H30N2O3
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0535704
|
4-(3-hydroxyphenyl)-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H28N2O3
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
Ki = 727 nM
|
|
|
|
CP0538318
|
4-(4-hydroxyphenyl)-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H28N2O3
|
2
|
| 1 |
EC50 > 1000 nM
|
|
|
| 2 |
Ki = 606 nM
|
|
|
|
CP0471523
|
4-[2-(2-fluorophenyl)ethyl]-2-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C25H31FN2O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0471525
|
4-methyl-2-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C23H28N2O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0484185
|
4-methyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
Show/Hide
|
C17H24N2O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0549539
|
N-[[4-[4-(2-hydroxy-2-phenylethyl)piperazin-1-yl]oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C27H35F3N4O3
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0573261
|
N-[[4-(2-benzyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl)oxan-4-yl]methyl]-N-[6-(trifluoromethyl)pyridin-2-yl]propanamide
Show/Hide
|
C28H35F3N4O2
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0041613
|
Anapriline
Show/Hide
|
C16H21NO2
|
2
|
| 1 |
EC50 > 5011.87 nM
|
|
|
| 2 |
IC50 > 5011.87 nM
|
|
|
|
CP0066236
|
1-(dimethylamino)-3-[(2-methyl-1H-1,2-benzazaborinin-8-yl)oxy]propan-2-ol
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C14H21BN2O2
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2
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| 1 |
EC50 > 5011.87 nM
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| 2 |
IC50 > 5011.87 nM
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CP0366351
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1-(dimethylamino)-3-[(2-methyl-1H-1,2-benzazaborinin-5-yl)oxy]propan-2-ol
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C14H21BN2O2
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2
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| 1 |
EC50 > 5011.87 nM
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| 2 |
IC50 > 5011.87 nM
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CP0235395
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(S)-1-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carboxylic acid [(S)-1-((S)-1-carbamoyl-2-phenyl-ethylcarbamoyl)-2-(1H-indol-3-yl)-ethyl]-amide
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C34H38N6O5
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2
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| 1 |
IC50 = 3.2 nM
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| 2 |
Ki = 0.76 nM
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CP0376671
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(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
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C56H70N10O9S
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2
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| 1 |
IC50 = 12 nM
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| 2 |
Ki = 0.73 nM
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CP0413770
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(2S)-1-[(2S)-2-(2-aminodecanoylamino)-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
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C66H89N11O10S
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2
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| 1 |
IC50 = 45 nM
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| 2 |
Ki = 3.87 nM
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CP0064900
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methyl (4aR,5S,8aR)-4-[2-(3,4-dichlorophenyl)acetyl]-5-pyrrolidin-1-yl-2,3,4a,5,6,7,8,8a-octahydroquinoxaline-1-carboxylate
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C22H29Cl2N3O3
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2
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| 1 |
IC50 > 1000 nM
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| 2 |
Ki = 2355 nM
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CP0380896
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1-[(4aR,8S,8aR)-4-benzyl-8-pyrrolidin-1-yl-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-2-(3,4-dichlorophenyl)ethanone
Show/Hide
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C27H33Cl2N3O
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2
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| 1 |
IC50 > 1000 nM
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| 2 |
Ki = 3900 nM
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CP0429065
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1-[(4aR,8S,8aS)-8-pyrrolidin-1-yl-3,4,4a,5,6,7,8,8a-octahydro-2H-quinoxalin-1-yl]-2-(3,4-dichlorophenyl)ethanone
Show/Hide
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C20H27Cl2N3O
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1
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| 1 |
IC50 > 1000 nM
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CP0448281
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1-[(4aR,8S,8aR)-4-benzyl-8-pyrrolidin-1-yl-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-2-phenylethanone
Show/Hide
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C27H35N3O
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1
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| 1 |
IC50 > 1000 nM
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CP0448282
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1-[(4aR,8S,8aS)-8-pyrrolidin-1-yl-3,4,4a,5,6,7,8,8a-octahydro-2H-quinoxalin-1-yl]-2-phenylethanone
Show/Hide
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C20H29N3O
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1
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| 1 |
IC50 > 1000 nM
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CP0924056
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N-benzyl-2-hydroxy-N-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}acetamide
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C24H30N2O3
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1
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| 1 |
Ki = 0.07943 nM
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CP0411192
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3-[(1S,5R)-8-[2-[benzyl-(2-hydroxyacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
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C25H31N3O3
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1
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| 1 |
Ki = 0.1 nM
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CP0107231
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3-[3,4-Dimethyl-1-(3-phenyl-propyl)-piperidin-4-yl]-phenol
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C22H29NO
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1
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| 1 |
Ki = 0.1 nM
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CP0408353
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3-[(1R,5S)-8-[2-[cyclohexylmethyl-(2-methylsulfonylacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
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C26H39N3O4S
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2
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| 1 |
Ki = 0.1 nM
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| 2 |
Ki = 10 nM
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CP0412120
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3-[(1S,5R)-8-[2-[cyclohexylmethyl-(2-hydroxyacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
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C25H37N3O3
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2
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| 1 |
Ki = 0.1 nM
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| 2 |
Ki = 10 nM
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CP0437954
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3-[(1R,5S)-8-[3-[2-ethylbutyl-(2-hydroxyacetyl)amino]propyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
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C25H39N3O3
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1
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| 1 |
Ki = 0.1 nM
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CP0472100
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3-[(1S,5R)-8-[2-[acetyl(cyclohexylmethyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
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C25H37N3O2
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1
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| 1 |
Ki = 0.1 nM
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CP0536346
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N-[2-[(1R,5S)-3-(3-carbamoylphenyl)-8-azabicyclo[3.2.1]octan-8-yl]ethyl]-N-(cyclohexylmethyl)furan-2-carboxamide
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C28H37N3O3
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1
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| 1 |
Ki = 0.1 nM
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CP0444103
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Axelopran sulfate
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C26H41N3O8S
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2
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| 1 |
Ki = 0.1259 nM
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| 2 |
Ki = 0.1585 nM
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CP0862451
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3-endo-(8-{2-[cyclohexylmethyl-((S)-2,3-dihydroxy-propionyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide glycolate
Show/Hide
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C28H41N3O7
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1
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| 1 |
Ki = 0.1259 nM
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CP0864447
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3-endo-(8-{2-[cyclohexylmethyl-((S)-2,3-dihydroxy-propionyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide oxalate
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C28H41N3O8
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1
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| 1 |
Ki = 0.1259 nM
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CP0914429
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AXELOPRAN
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C26H39N3O4
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1
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| 1 |
Ki = 0.1259 nM
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CP0382973
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3-[(1S,5R)-8-[2-[cyclohexylmethyl(2,2-dimethylpropanoyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
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C28H43N3O2
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1
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| 1 |
Ki = 0.1259 nM
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CP0437947
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methyl N-[2-[(1S,5R)-3-(3-carbamoylphenyl)-8-azabicyclo[3.2.1]octan-8-yl]ethyl]-N-(cyclohexylmethyl)carbamate
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C25H37N3O3
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1
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| 1 |
Ki = 0.1259 nM
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CP0472098
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3-[(1S,5R)-8-[2-[(4,4-difluorocyclohexyl)methyl-(2-hydroxyacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
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C25H35F2N3O3
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2
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| 1 |
Ki = 0.1259 nM
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| 2 |
Ki = 10 nM
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CP0848588
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3-endo-(8-{2-[(2-methanesulfonylacetyl)phenethylamino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
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C29H36F3N3O6S
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1
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| 1 |
Ki = 0.1585 nM
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CP0508116
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3-[8-(3-phenylpropyl)-8-azabicyclo[3.2.1]octan-3-yl]phenol
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C22H27NO
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1
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| 1 |
Ki = 0.1585 nM
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CP0048724
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(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(oxidanyl)-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
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C20H23NO4
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1
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| 1 |
Ki = 0.1585 nM
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CP0437950
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3-[(1S,5R)-8-[2-[2-ethylbutyl-(2-hydroxyacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
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C24H37N3O3
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1
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| 1 |
Ki = 0.1585 nM
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CP0380556
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3-[(1R,5S)-8-[2-[cyclohexylmethyl(propan-2-ylcarbamoyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
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C27H42N4O2
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2
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| 1 |
Ki = 0.1995 nM
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| 2 |
Ki = 10 nM
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CP0437945
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3-[(1R,5S)-8-[2-[cyclohexylmethyl(dimethylsulfamoyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
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C25H40N4O3S
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1
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| 1 |
Ki = 0.1995 nM
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CP0958424
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trans-2',3',4',9'-Tetrahydro-N,N,2'-trimethyl-4-phenyl-spiro[cyclohexane-1,1'-pyrido[3,4-b]-indol]-4-amine Dihydrochloride
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C25H32ClN3
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1
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| 1 |
Ki = 0.24 nM
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CP0437946
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3-[(1R,5S)-8-[2-[cyclohexylmethyl(methylsulfonyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
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C24H37N3O3S
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1
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| 1 |
Ki = 0.2512 nM
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CP0437948
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3-[(1S,5R)-8-[2-(cyclohexylmethylamino)ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
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C23H35N3O
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1
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| 1 |
Ki = 0.2512 nM
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CP0459481
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3-[(1S,5R)-8-[2-[cyclopentylmethyl-(2-hydroxyacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
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C24H35N3O3
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1
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| 1 |
Ki = 0.2512 nM
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CP0764294
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trans-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-4-amine hydrochloride
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C24H29ClN2O
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2
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| 1 |
Ki = 0.26 nM
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| 2 |
Ki = 0.6 nM
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CP0868690
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3-cyclopentyl-N-((trans)-4-(dimethylamino)-4-phenylcyclohexyl)propanamide hydrochloride
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C22H35ClN2O
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1
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| 1 |
Ki = 0.3 nM
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CP0013111
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ADL 8-2698
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C25H32N2O4
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1
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| 1 |
Ki = 0.3162 nM
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CP0437949
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(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoic acid
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C23H29NO3
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1
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| 1 |
Ki = 0.3162 nM
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CP0437953
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2-[[(2S)-2-benzyl-3-[(3R,4R)-4-(3-hydroxyphenyl)-3-methylpiperidin-1-yl]propanoyl]amino]acetic acid
Show/Hide
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C24H30N2O4
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1
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| 1 |
Ki = 0.3162 nM
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CP0508735
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2-hydroxypropane-1,2,3-tricarboxylic acid;N-methyl-1'-phenylspiro[4,9-dihydro-3H-pyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine
Show/Hide
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C29H34N2O8
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1
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| 1 |
Ki = 0.36 nM
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CP0472099
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3-[(1R,5S)-8-[2-[cyclohexylmethyl-[2-(2H-tetrazol-5-yl)acetyl]amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
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C26H37N7O2
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1
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| 1 |
Ki = 0.3981 nM
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CP0934282
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US9120797, 33
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C25H31N3
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1
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| 1 |
Ki = 0.5 nM
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CP0443839
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US9120797, 53
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C25H31N3
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1
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| 1 |
Ki = 0.6 nM
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CP0528546
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2-cyclobutyl-1-[8-(dimethylamino)-8-phenyl-2-azaspiro[4.5]decan-2-yl]ethanone
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|
C23H34N2O
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1
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| 1 |
Ki = 0.6 nM
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CP0437951
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3-[(1S,5R)-8-[2-[(2-hydroxyacetyl)-(2-phenylethyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
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C26H33N3O3
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1
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| 1 |
Ki = 0.631 nM
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CP0437944
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3-[(1S,5R)-8-[5-[2-ethylbutyl-(2-hydroxyacetyl)amino]pentyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
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C27H43N3O3
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1
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| 1 |
Ki = 0.631 nM
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CP0533944
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3-[(1S,5R)-8-[4-[2-ethylbutyl-(2-hydroxyacetyl)amino]butyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
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C26H41N3O3
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1
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| 1 |
Ki = 0.631 nM
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CP0399457
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US9120797, 34
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C24H28FN3
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1
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| 1 |
Ki = 0.7 nM
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CP0437952
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3-[(1R,5S)-8-[2-[cyclohexylmethyl-(2,2,2-trifluoroacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
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C25H34F3N3O2
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1
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| 1 |
Ki = 0.7943 nM
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CP0437955
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3-[(1S,5R)-8-[2-[hexyl-(2-hydroxyacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
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C24H37N3O3
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1
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| 1 |
Ki = 0.7943 nM
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CP0530787
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3-[(1S,5R)-8-[2-[(2-hydroxyacetyl)-(3-phenylpropyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
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C27H35N3O3
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2
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| 1 |
Ki = 0.7943 nM
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| 2 |
Ki = 10 nM
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CP0390125
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1-[(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,7,9-trihydroxy-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-6-yl]ethanone
Show/Hide
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C22H25NO5
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1
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| 1 |
Ki = 0.95 nM
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CP0074075
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(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,7,9-trihydroxy-N-phenyl-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-6-carboxamide
Show/Hide
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C27H28N2O5
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1
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| 1 |
Ki = 1 nM
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CP0437943
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3-[(1S,5R)-8-[6-[2-ethylbutyl-(2-hydroxyacetyl)amino]hexyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
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C28H45N3O3
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1
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| 1 |
Ki = 1 nM
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CP0556855
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1-[2-[8-(dimethylamino)-8-phenyl-2-azaspiro[4.5]decan-2-yl]-2-oxoethyl]cyclobutane-1-carbonitrile
Show/Hide
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C24H33N3O
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1
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| 1 |
Ki = 1 nM
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CP0402032
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2-(8-cyclodecyl-1-oxo-4-phenyl-2,3,8-triazaspiro[4.5]dec-3-en-2-yl)-N-methylacetamide
Show/Hide
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C26H38N4O2
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1
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| 1 |
Ki = 1.1 nM
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CP0921241
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trans-4',9'-Dihydro-6'-methoxy-N,N-dimethyl-4-phenyl-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-4-amine Hydrochloride
Show/Hide
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C25H31ClN2O2
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1
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| 1 |
Ki = 1.1 nM
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CP0399458
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US9120797, 45
Show/Hide
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C24H28N2O2
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1
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| 1 |
Ki = 1.1 nM
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CP0074074
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Naldemedine
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C32H34N4O6
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1
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| 1 |
Ki = 1.1 nM
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CP0421135
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(4R,4aS,7aR,12bS)-N-benzyl-3-(cyclopropylmethyl)-4a,7,9-trihydroxy-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-6-carboxamide
Show/Hide
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C28H30N2O5
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1
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| 1 |
Ki = 1.1 nM
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CP0559603
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2-(cyclopentylmethyl)-N,N-dimethyl-8-thiophen-2-yl-2-azaspiro[4.5]decan-8-amine
Show/Hide
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C21H34N2S
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1
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| 1 |
Ki = 1.14 nM
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CP0462870
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US9120797, 28
Show/Hide
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C23H26N2O
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1
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| 1 |
Ki = 1.2 nM
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CP0430177
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1-[2-[8-(dimethylamino)-3-oxo-8-phenyl-2-azaspiro[4.5]decan-2-yl]ethyl]cyclobutane-1-carbonitrile
Show/Hide
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C24H33N3O
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1
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| 1 |
Ki = 1.2 nM
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CP0542478
|
CHEMBL4551066
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C23H27NO5
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1
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| 1 |
Ki = 1.4 nM
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CP0550968
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3-[(1R,5S)-8-[2-[cyclobutylmethyl-(2-hydroxyacetyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
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C23H33N3O3
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1
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| 1 |
Ki = 1.585 nM
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CP0381394
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(2S)-1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C47H61N9O8S
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1
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| 1 |
Ki = 1.6 nM
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CP0239639
|
US8536192, I-135
Show/Hide
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C26H30N2O7
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1
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| 1 |
Ki = 1.6 nM
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CP0443838
|
US9120797, 32
Show/Hide
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C26H30FN3O
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1
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| 1 |
Ki = 1.7 nM
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CP0931324
|
trans-4-(dimethylamino)-1-phenethyl-4-phenylcyclohexanol hydrochloride
Show/Hide
|
C22H30ClNO
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1
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| 1 |
Ki = 1.9 nM
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CP0456027
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N,N-dimethyl-1'-phenylspiro[2,3,4,9-tetrahydrocarbazole-1,4'-cyclohexane]-1'-amine
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C25H30N2
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1
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| 1 |
Ki = 1.95 nM
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CP0399455
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US9120797, 13
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C25H30N2O2
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1
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| 1 |
Ki = 2 nM
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CP0508699
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N-[4-(dimethylamino)-4-phenylcyclohexyl]-2-phenylacetamide;hydrochloride
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C22H28N2O
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1
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| 1 |
Ki = 2.1 nM
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CP0406769
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US9120797, 23
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C24H27FN2O
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1
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| 1 |
Ki = 2.1 nM
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CP0498920
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2-[1-(1-Cyclodecyl-piperidin-4-yl)-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-benzo[1,2,6]thiadiazin-3-yl]-N-methyl-acetamide
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C25H40N4O3S
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1
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| 1 |
Ki = 2.2 nM
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CP0038839
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(4R,4aS,7aR,12bS)-3-allyl-4a,9-dihydroxy-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one;hydrochloride
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C19H21NO4
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1
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| 1 |
Ki = 2.3 nM
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CP0882242
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US9120797, 46
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C26H31N3O2
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1
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| 1 |
Ki = 2.3 nM
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CP0458192
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(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,7,9-trihydroxy-N-(1H-indol-6-yl)-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-6-carboxamide
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C29H29N3O5
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1
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| 1 |
Ki = 2.4 nM
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CP0868666
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trans-4',9'-Dihydro-N,N,6'-trimethyl-4-phenyl-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-4-amine Hemicitrate
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C31H38N2O8
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1
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| 1 |
Ki = 2.7 nM
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CP0406770
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US9120797, 26
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C25H30N2O
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1
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| 1 |
Ki = 2.7 nM
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CP0896605
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US9120797, 47
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C25H31N3O
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1
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| 1 |
Ki = 2.7 nM
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CP0430176
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2-butyl-N,N-dimethyl-8-thiophen-2-yl-2-azaspiro[4.5]decan-8-amine
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C19H32N2S
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1
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| 1 |
Ki = 2.8 nM
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CP0910341
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trans-N4-benzyl-N1,N1-dimethyl-1-phenylcyclohexane-1,4-diamine dihydrochloride
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C21H30Cl2N2
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1
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| 1 |
Ki = 3 nM
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CP0418728
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N,N-dimethyl-1'-phenylspiro[4,9-dihydro-3H-thiopyrano[3,4-b]indole-1,4'-cyclohexane]-1'-amine;2-hydroxypropane-1,2,3-tricarboxylic acid
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C30H36N2O7S
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1
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| 1 |
Ki = 3.1 nM
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CP0383725
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US9120797, 4
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C24H28N2S
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1
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| 1 |
Ki = 3.1 nM
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CP0074073
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(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,7,9-trihydroxy-N-propan-2-yl-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-6-carboxamide
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C24H30N2O5
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1
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| 1 |
Ki = 3.4 nM
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CP0549304
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1-[2-[8-(dimethylamino)-8-phenyl-2-azaspiro[4.5]decan-2-yl]ethyl]cyclobutane-1-carbonitrile
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C24H35N3
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1
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| 1 |
Ki = 3.5 nM
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CP0504637
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2-(3-(1-(biphenyl-2-ylmethyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide
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C28H30N4O2
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1
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| 1 |
Ki = 3.7 nM
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CP0477174
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[(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,7,9-trihydroxy-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinolin-6-yl]-pyrrolidin-1-ylmethanone
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C25H30N2O5
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1
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| 1 |
Ki = 4 nM
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CP0549302
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1-[8-cyclopentyl-8-(dimethylamino)-2-azaspiro[4.5]decan-2-yl]-2-cyclopropylethanone
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C21H36N2O
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1
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| 1 |
Ki = 4 nM
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CP0530878
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8-benzyl-2-butyl-N,N-dimethyl-2-azaspiro[4.5]decan-8-amine
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C22H36N2
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1
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| 1 |
Ki = 4.5 nM
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CP0485872
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1-[8-(dimethylamino)-8-(3-methylthiophen-2-yl)-2-azaspiro[4.5]decan-2-yl]-3-methylbutan-1-one
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C21H34N2OS
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1
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| 1 |
Ki = 4.8 nM
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CP0391102
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(4R,4aS,7aR,12bS)-N-(4-cyanophenyl)-3-(cyclopropylmethyl)-4a,7,9-trihydroxy-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-6-carboxamide
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C28H27N3O5
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1
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| 1 |
Ki = 5.1 nM
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CP0463352
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2-(8-(4-isopropylcyclohexyl)-1-oxo-4-phenyl-2,3,8-triazaspiro[4.5]dec-3-en-2-yl)-N-methylacetamide
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C25H36N4O2
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1
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| 1 |
Ki = 5.2 nM
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CP0880333
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METHYLNALTREXONE BROMIDE
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C21H26BrNO4
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2
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| 1 |
Ki = 5.48 nM
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| 2 |
Ki = 7.943 nM
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CP0402030
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2-(8-(decahydronaphthalen-2-yl)-1-oxo-4-phenyl-2,3,8-triazaspiro[4.5]dec-3-en-2-yl)-N-methylacetamide
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C26H36N4O2
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1
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| 1 |
Ki = 5.8 nM
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CP0399637
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2-(4,5-dimethoxy-2-pyrrolidin-1-ylsulfonylphenyl)-N-[(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl]-N-methylacetamide
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C27H37N3O6S
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1
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| 1 |
Ki = 5.9 nM
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CP0451737
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4-N-(1H-indol-3-ylmethyl)-1-N,1-N-dimethyl-1-phenylcyclohexane-1,4-diamine
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C23H29N3
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1
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| 1 |
Ki = 6.4 nM
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CP0440569
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2-[6-[benzyl(methyl)sulfamoyl]-1,3-benzodioxol-5-yl]-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
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C30H35N3O5S
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1
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| 1 |
Ki = 6.5 nM
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CP0518894
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US9120797, 49
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C23H25FN2O
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1
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| 1 |
Ki = 6.8 nM
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CP0443836
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US9120797, 22
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C24H27FN2O
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1
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| 1 |
Ki = 7.2 nM
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CP0498921
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2-(8-(4-tert-butylcyclohexyl)-1-oxo-4-phenyl-2,3,8-triazaspiro[4.5]dec-3-en-2-yl)-N-methylacetamide
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C26H38N4O2
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1
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| 1 |
Ki = 7.3 nM
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CP0432949
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(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,7,9-trihydroxy-N-[2-(3-methyl-1,2,4-oxadiazol-5-yl)propan-2-yl]-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-6-carboxamide
Show/Hide
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C27H32N4O6
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1
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| 1 |
Ki = 7.3 nM
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CP0485883
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1-[8-(dimethylamino)-8-(3-methylthiophen-2-yl)-2-azaspiro[4.5]decan-2-yl]butan-1-one
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C20H32N2OS
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1
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| 1 |
Ki = 7.6 nM
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CP0261931
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(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-dihydroxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-3-ium-7-one
Show/Hide
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C21H26NO4+
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1
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| 1 |
Ki = 7.943 nM
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CP0477173
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(1S,2S,10R,18R)-7-amino-19-(cyclopropylmethyl)-5-methyl-11-oxa-6,8,19-triazahexacyclo[10.9.1.01,10.02,18.04,9.016,22]docosa-4,6,8,12,14,16(22)-hexaene-2,13-diol
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C23H26N4O3
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1
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| 1 |
Ki = 8.6 nM
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CP0309394
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1-ethoxymethyl-3-{1-[3-(5-methoxy-2-methylphenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydrobenzimidazol-2-one
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C29H41N3O4
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1
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| 1 |
Ki = 9 nM
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CP0436372
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2-(4,5-dimethoxy-2-morpholin-4-ylsulfonylphenyl)-N-[(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl]-N-methylacetamide
Show/Hide
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C27H37N3O7S
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1
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| 1 |
Ki = 9 nM
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CP0888228
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trans-N4-(2-(5-fluoro-1H-indol-3-yl)ethyl)-N1,N1-dimethyl-1-phenylcyclohexane-1,4-diamine dihydrochloride
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C24H32Cl2FN3
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1
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| 1 |
Ki = 9 nM
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CP0296160
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(2S)-5-amino-2-[[(2S)-4-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-carboxypropanoyl]amino]-4-oxobutanoyl]amino]-5-oxopentanoic acid
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C99H155N31O23
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1
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| 1 |
Ki = 9.4 nM
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CP0391101
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(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,7,9-trihydroxy-N-pyridin-2-yl-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-6-carboxamide
Show/Hide
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C26H27N3O5
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1
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| 1 |
Ki = 9.8 nM
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CP0847246
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3-endo-(8-{2-[((S)-2,3-dihydroxypropionyl)-(4-trifluoromethyl-cyclohexylmethyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
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C29H39F6N3O6
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1
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| 1 |
Ki = 10 nM
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CP0847247
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3-endo-(8-{2-[[2-(4-hydroxyphenyl)ethyl]-(2-methanesulfonyl-acetyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C29H36F3N3O7S
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1
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| 1 |
Ki = 10 nM
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CP0847248
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3-endo-(8-{2-[(4-fluorobenzyl)-(2-hydroxyacetyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
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C27H31F4N3O5
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1
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| 1 |
Ki = 10 nM
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CP0847249
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3-endo-(8-{2-[cyclopentylmethyl-((S)-2,3-dihydroxypropionyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C27H38F3N3O6
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1
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| 1 |
Ki = 10 nM
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CP0847250
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3-endo-(8-{2-[(4-fluorocyclohexylmethyl)-(2-hydroxyacetyl)amino]-ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
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C27H37F4N3O5
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1
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| 1 |
Ki = 10 nM
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CP0847276
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3-endo-(8-{3-[benzyl-(2-methanesulfonylacetyl)amino]propyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
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C29H36F3N3O6S
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1
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| 1 |
Ki = 10 nM
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CP0847278
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N-adamantan-1-ylmethyl-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}acetamide trifluoroacetate salt
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C30H41F3N2O4
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1
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| 1 |
Ki = 10 nM
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CP0847279
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3-endo-(8-{2-[cyclohexylmethyl-(2-methoxyacetyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
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C28H40F3N3O5
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1
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| 1 |
Ki = 10 nM
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CP0847280
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3-endo-(8-{2-[cyclohexylmethyl-(1-hydroxy-cyclopropanecarbonyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide
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C27H39N3O3
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1
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| 1 |
Ki = 10 nM
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CP0847283
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3-endo-(8-{2-[cyclopentylmethyl-(trans-4-hydroxycyclohexanecarbonyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C31H44F3N3O5
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1
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| 1 |
Ki = 10 nM
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CP0847288
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3-endo-(8-{2-[(2-hydroxyacetyl)-(3-hydroxy-adamantan-1-ylmethyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)benzamide
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C29H41N3O4
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1
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| 1 |
Ki = 10 nM
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CP0847289
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(3-endo-(8-(2-(cyclohexylmethyl)(N,N-dimethylsulfamoyl)amino)ethyl)-8-azabicyclo[3.2.1]oct-3-yl)benzamide trifluoroacetate salt
Show/Hide
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C27H41F3N4O5S
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1
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| 1 |
Ki = 10 nM
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CP0848582
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3-endo-(8-{2-[cyclohexylmethyl-(2-dimethylamino-acetyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide
Show/Hide
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C27H42N4O2
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1
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| 1 |
Ki = 10 nM
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CP0848583
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4-(cyclohexylmethyl-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}carbamoyl)-3,3-dimethylbutyric acid
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C29H44N2O4
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1
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| 1 |
Ki = 10 nM
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CP0848584
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N-cyclohexylmethyl-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}succinamic acid
Show/Hide
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C26H38N2O4
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1
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| 1 |
Ki = 10 nM
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CP0848586
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N-benzyl-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}succinamic acid
Show/Hide
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C26H32N2O4
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1
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| 1 |
Ki = 10 nM
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CP0848587
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N-cyclohexylmethyl-N-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}acetamide
Show/Hide
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C24H36N2O2
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1
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| 1 |
Ki = 10 nM
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CP0848592
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N-(2,6-Difluoro-benzyl)-N-{2-[3-(3-hydroxy-phenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}-succinamic acid
Show/Hide
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C26H30F2N2O4
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1
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| 1 |
Ki = 10 nM
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CP0848593
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3-endo-(8-{2-[1-cyclohexylmethyl-3-(4-fluorobenzyl)-ureido]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)benzamide
Show/Hide
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C31H41FN4O2
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1
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| 1 |
Ki = 10 nM
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CP0848594
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N-(2,6-difluorobenzyl)-2-hydroxy-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}acetamide
Show/Hide
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C24H28F2N2O3
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1
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| 1 |
Ki = 10 nM
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CP0848595
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N-(3-fluorobenzyl)-2-hydroxy-N-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]-ethyl}succinamic acid
Show/Hide
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C26H31FN2O5
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1
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| 1 |
Ki = 10 nM
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CP0848596
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N-cyclohexylmethyl-N-{2-[3-endo-(3-hydroxy-phenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}-2-methanesulfonylacetamide
Show/Hide
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C25H38N2O4S
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1
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| 1 |
Ki = 10 nM
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CP0851217
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3-endo-(8-{2-[cyclohexylmethyl-((S)-2-hydroxy-3-phenylpropionyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)benzamide
Show/Hide
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C32H43N3O3
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1
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| 1 |
Ki = 10 nM
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CP0851218
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(S)-2-hydroxy-4-methyl-pentanoic acid cyclohexylmethyl-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}amide
Show/Hide
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C28H44N2O3
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1
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| 1 |
Ki = 10 nM
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CP0851219
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N-(2,6-difluorobenzyl)-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}acetamide
Show/Hide
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C24H28F2N2O2
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1
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| 1 |
Ki = 10 nM
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CP0851220
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N-(3-fluorobenzyl)-2-hydroxy-N-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}acetamide
Show/Hide
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C24H29FN2O3
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1
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| 1 |
Ki = 10 nM
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CP0851287
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3-endo-(8-{2-[(2,2-difluoro-2-phenylethyl)-((S)-2,3-dihydroxy-propionyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C29H34F5N3O6
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1
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| 1 |
Ki = 10 nM
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CP0851288
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3-endo-{8-[2-(benzyl-methanesulfonylamino)ethyl]-8-aza-bicyclo[3.2.1]oct-3-yl}-benzamide trifluoroacetate salt
Show/Hide
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C26H32F3N3O5S
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1
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| 1 |
Ki = 10 nM
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CP0851290
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3-endo-(8-{2-[cyclopentylmethyl-(2-hydroxyacetyl)amino]-ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide
Show/Hide
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C26H36F3N3O5
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1
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| 1 |
Ki = 10 nM
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CP0851291
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3-endo-(8-{3-[benzyl-(2,2-dimethylpropionyl)amino]propyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C31H40F3N3O4
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1
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| 1 |
Ki = 10 nM
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CP0851292
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acetic acid(benzyl-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]-ethyl}carbamoyl)methyl ester trifluoroacetate salt
Show/Hide
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C28H33F3N2O6
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1
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| 1 |
Ki = 10 nM
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CP0851293
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3-endo-(8-{2-[(2-tert-butoxyacetyl)-(2,6-difluorobenzyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)benzamide trifluoroacetate salt
Show/Hide
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C31H38F5N3O5
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1
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| 1 |
Ki = 10 nM
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CP0851294
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N-(2,6-difluorobenzyl)-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}succinamic acid trifluoroacetate salt
Show/Hide
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C28H31F5N2O6
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1
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| 1 |
Ki = 10 nM
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CP0851296
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3-endo-(8-{2-[adamantan-1-ylmethyl-(2-hydroxyacetyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C31H42F3N3O5
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1
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| 1 |
Ki = 10 nM
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CP0851298
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(S)-N-cyclohexylmethyl-2-dimethylamino-N-{2-[3-endo-(3-hydroxy-phenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}-3-phenylpropionamide
Show/Hide
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C33H47N3O2
|
1
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| 1 |
Ki = 10 nM
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CP0851299
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N-benzyl-3-cyclopentyl-N-{(R)-2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-1-methylethyl}propionamide
Show/Hide
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C31H42N2O2
|
1
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| 1 |
Ki = 10 nM
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CP0851300
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3-endo-(8-{2-[(2-cyclohexylethyl)-(2-hydroxyacetyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide
Show/Hide
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C26H39N3O3
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1
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| 1 |
Ki = 10 nM
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CP0851302
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3-endo-(8-{2-[cyclobutylmethyl-(3-hydroxy-2-hydroxymethyl-2-methyl-propionyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C28H40F3N3O6
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1
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| 1 |
Ki = 10 nM
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CP0851310
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3-endo-(8-2-[(4,4-difluorocyclohexylmethyl)-((S)-2-hydroxypropionyl)-amino]ethyl-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C28H38F5N3O5
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1
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| 1 |
Ki = 10 nM
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CP0851311
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3-endo-(8-{2-[(4,4-difluorocyclohexylmethyl)-((S)-4-dimethylamino-2-hydroxybutyryl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide bis trifluoroacetate salt
Show/Hide
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C33H46F8N4O7
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1
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| 1 |
Ki = 10 nM
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CP0851312
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3-endo-(8-{2-[(4,4-difluorocyclohexylmethyl)-((R)-2,3-dihydroxy-propionyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C28H38F5N3O6
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1
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| 1 |
Ki = 10 nM
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CP0851341
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N-adamantan-1-ylmethyl-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}succinamic acid Trifluoroacetate salt
Show/Hide
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C32H43F3N2O6
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1
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| 1 |
Ki = 10 nM
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CP0851342
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3-endo-(8-{2-[((S)-2,3-dihydroxypropionyl)-(3-hydroxy-adamantan-1-ylmethyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide
Show/Hide
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C30H43N3O5
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1
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| 1 |
Ki = 10 nM
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CP0851344
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3-endo-(8-{3-[benzyl-(2,3-dihydroxybutyryl)amino]propyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C30H38F3N3O6
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1
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| 1 |
Ki = 10 nM
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CP0851345
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3-endo-(8-{2-[(2,6-difluorobenzyl)-((S)-2-hydroxy-4-methylpentanoyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)benzamide trifluoroacetate salt
Show/Hide
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C31H38F5N3O5
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1
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| 1 |
Ki = 10 nM
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CP0851346
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3-endo-(8-{2-[cyclohexylmethyl-((S)-2-hydroxy-4-methylpentanoyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide
Show/Hide
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C29H45N3O3
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1
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| 1 |
Ki = 10 nM
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CP0851349
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3-endo-(8-{2-[cyclobutylmethyl-(2-methanesulfonylacetyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C26H36F3N3O6S
|
1
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| 1 |
Ki = 10 nM
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CP0851371
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N-cyclohexylmethyl-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}succinamic acid methyl ester
Show/Hide
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C27H40N2O4
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1
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| 1 |
Ki = 10 nM
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CP0851372
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3-endo-(8-{2-[cyclobutylmethyl-(2-methanesulfonyl-2-methyl-propionyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C28H40F3N3O6S
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1
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| 1 |
Ki = 10 nM
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CP0851373
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3-endo-(8-{2-[cyclohexylmethyl-((S)-4-dimethylamino-2-hydroxy-butyryl)-amino]-ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide
Show/Hide
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C29H46N4O3
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1
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| 1 |
Ki = 10 nM
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CP0851374
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3-endo-(8-{2-[(3-cyclohexylpropyl)-(2-hydroxyacetyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide
Show/Hide
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C27H41N3O3
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1
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| 1 |
Ki = 10 nM
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CP0858822
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cyclopentanecarboxylic acid benzyl-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}-amide
Show/Hide
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C28H36N2O2
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1
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| 1 |
Ki = 10 nM
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CP0858828
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3-endo-{8-[3-(acetylcyclohexylmethylamino)-propyl]-8-azabicyclo[3.2.1]oct-3-yl}benzamide
Show/Hide
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C26H39N3O2
|
1
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| 1 |
Ki = 10 nM
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CP0862429
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3-endo-(8-{2-(4-trifluoromethylbenzyl)-(N,N-dimethylsulfamoyl)amino-ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C28H34F6N4O5S
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1
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| 1 |
Ki = 10 nM
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CP0862430
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3-endo-(8-{2-[cyclobutylmethyl-((S)-2,3-dihydroxypropionyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C26H36F3N3O6
|
1
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| 1 |
Ki = 10 nM
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CP0862431
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3-endo-(8-{2-[cyclopentylmethyl-((R)-2,3-dihydroxypropionyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C27H38F3N3O6
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1
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| 1 |
Ki = 10 nM
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CP0862441
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3-endo-(8-{2-[(2,6-difluorobenzyl)-(1-hydroxycyclopropanecarbonyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)benzamide trifluoroacetate salt
Show/Hide
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C29H32F5N3O5
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1
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| 1 |
Ki = 10 nM
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CP0862442
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3-endo-(8-{2-[(2,6-difluorobenzyl)-((S)-2,3-dihydroxypropionyl)-amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide trifluoroacetate salt
Show/Hide
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C28H32F5N3O6
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1
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| 1 |
Ki = 10 nM
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CP0862443
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3-endo-(8-{2-[(2,6-difluorobenzyl)-(2-hydroxy-2-methylpropionyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C29H34F5N3O5
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1
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| 1 |
Ki = 10 nM
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CP0862444
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N-cyclohexylmethyl-2-hydroxy-N-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}-2-(S)-phenylacetamide
Show/Hide
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C30H40N2O3
|
1
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| 1 |
Ki = 10 nM
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CP0862445
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3-endo-{8-[2-(1-cyclohexylmethyl-3-pentylureido)-ethyl]-8-azabicyclo[3.2.1]oct-3-yl}benzamide
Show/Hide
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C29H46N4O2
|
1
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| 1 |
Ki = 10 nM
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CP0862446
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N-(4-fluorobenzyl)-2-hydroxy-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}acetamide
Show/Hide
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C24H29FN2O3
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1
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| 1 |
Ki = 10 nM
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CP0862447
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N-(3-fluorobenzyl)-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}-2-methanesulfonyl-acetamide
Show/Hide
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C25H31FN2O4S
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1
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| 1 |
Ki = 10 nM
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CP0862448
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3-endo-(8-{2-[benzyl-(1-hydroxy-cyclopropanecarbonyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C29H34F3N3O5
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1
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| 1 |
Ki = 10 nM
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CP0862450
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cyclopentanecarboxylic acid(R)-benzyl-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-1-methylethyl}amide
Show/Hide
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C29H38N2O2
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1
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| 1 |
Ki = 10 nM
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CP0862452
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3-endo-(8-{2-[[2-(4-fluorophenyl)ethyl]-(2-methanesulfonyl-acetyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C29H35F4N3O6S
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1
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| 1 |
Ki = 10 nM
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CP0863578
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cyclopentanecarboxylic acid cyclohexylmethyl-{2-[3-endo-(3-hydroxy-phenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}amide
Show/Hide
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C28H42N2O2
|
1
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| 1 |
Ki = 10 nM
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CP0863580
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3-endo-(8-{2-[((S)-2,3-dihydroxypropionyl)-(4-methyl-cyclohexyl-methyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C29H42F3N3O6
|
1
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| 1 |
Ki = 10 nM
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CP0863581
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3-endo-(8-{2-[[2-(4-fluorophenyl)ethyl]-(2-hydroxyacetyl)amino]-ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C28H33F4N3O5
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1
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| 1 |
Ki = 10 nM
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CP0863582
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3-endo-(8-{2-[[2-(3-fluorophenyl)ethyl]-(2-hydroxyacetyl)amino]-ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C28H33F4N3O5
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1
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| 1 |
Ki = 10 nM
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CP0863583
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3-endo-(8-{2-[(2-hydroxyacetyl)-(4-trifluoromethylbenzyl)-amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C28H31F6N3O5
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1
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| 1 |
Ki = 10 nM
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CP0863585
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3-endo-(8-{2-[cyclobutylmethyl-((S)-2-hydroxypropionyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C26H36F3N3O5
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1
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| 1 |
Ki = 10 nM
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CP0863596
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N-benzyl-2-ethyl-N-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}butyramide
Show/Hide
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C28H38N2O2
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1
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| 1 |
Ki = 10 nM
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CP0863599
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3-sec-butyl-1-cyclohexylmethyl-1-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}-urea
Show/Hide
|
C27H43N3O2
|
1
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| 1 |
Ki = 10 nM
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CP0863601
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3-endo-(8-{2-[cyclopentylmethyl-(3-hydroxypropionyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C27H38F3N3O5
|
1
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| 1 |
Ki = 10 nM
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CP0864333
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3-endo-(8-{2-[cyclohexylmethyl-((S)-2-dimethylamino-3-phenyl-propionyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)benzamide
Show/Hide
|
C34H48N4O2
|
1
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| 1 |
Ki = 10 nM
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CP0864360
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3-endo-(8-{2-[benzyl-(2-hydroxy-2-methylpropionyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C29H36F3N3O5
|
1
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| 1 |
Ki = 10 nM
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CP0864361
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3-endo-(8-{2-[benzyl-(2-methanesulfonylacetyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C28H34F3N3O6S
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1
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| 1 |
Ki = 10 nM
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CP0864367
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N-benzyl-N-{(R)-2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]-1-methylethyl}succinamic acid
Show/Hide
|
C27H34N2O4
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1
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| 1 |
Ki = 10 nM
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CP0864384
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N-cyclohexylmethyl-N-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}propionamide
Show/Hide
|
C25H38N2O2
|
1
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| 1 |
Ki = 10 nM
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CP0864385
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3-endo-(8-{2-[(trans-4-hydroxycyclohexylmethyl)-((S)-2,3-dihydroxypropionyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide
Show/Hide
|
C26H39N3O5
|
1
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| 1 |
Ki = 10 nM
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CP0864453
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3-endo-[8-(2-{(2-hydroxyacetyl)-[2-(4-hydroxyphenyl)ethyl]-amino}ethyl)-8-azabicyclo[3.2.1]oct-3-yl]-benzamide trifluoroacetate salt
Show/Hide
|
C28H34F3N3O6
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1
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| 1 |
Ki = 10 nM
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CP0864454
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N-cyclohexylmethyl-2-hydroxy-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}acetamide
Show/Hide
|
C24H36N2O3
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1
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| 1 |
Ki = 10 nM
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CP0864455
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N-cyclohexylmethyl-3-cyclopentyl-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}propionamide
Show/Hide
|
C30H46N2O2
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1
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| 1 |
Ki = 10 nM
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CP0864926
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3-endo-(8-{2-[(4,4-difluorocyclohexylmethyl)-(2-hydroxyacetyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)benzamide phosphate
Show/Hide
|
C25H36F2N3O6P
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1
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| 1 |
Ki = 10 nM
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CP0864927
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N-{2-[3-endo-(3-carbamoyl-phenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}-N-cyclohexylmethyl-succinamic acid methyl ester
Show/Hide
|
C28H41N3O4
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1
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| 1 |
Ki = 10 nM
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CP0864928
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N-{2-[3-endo-(3-carbamoylphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}-N-cyclohexylmethyl-succinamic acid
Show/Hide
|
C27H39N3O4
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1
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| 1 |
Ki = 10 nM
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CP0864929
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1-cyclohexylmethyl-3-(3-fluorophenyl)-1-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}urea
Show/Hide
|
C29H38FN3O2
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1
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| 1 |
Ki = 10 nM
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CP0864930
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cyclohexanecarboxylic acid cyclohexylmethyl-{2-[3-endo-(3-hydroxy-phenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}amide
Show/Hide
|
C29H44N2O2
|
1
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| 1 |
Ki = 10 nM
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CP0864931
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3-endo-(8-{2-[(2-hydroxyacetyl)-(2,2,3,3-tetramethyl-cyclopropylmethyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide
Show/Hide
|
C26H39N3O3
|
1
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| 1 |
Ki = 10 nM
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CP0866144
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3-endo-(8-{2-[cyclohexylmethyl-((S)-4-diethylamino-2-hydroxybutyryl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide
Show/Hide
|
C31H50N4O3
|
1
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| 1 |
Ki = 10 nM
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CP0866151
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N-benzyl-2-cyclopentyl-N-{(R)-2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]-1-methylethyl}acetamide
Show/Hide
|
C30H40N2O2
|
1
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| 1 |
Ki = 10 nM
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CP0866159
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3-endo-(8-{2-[cyclopentylmethyl-(2,2-dimethylpropionyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C29H42F3N3O4
|
1
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| 1 |
Ki = 10 nM
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CP0866161
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3-endo-(8-{3-[benzyl-(2-hydroxy-2-methylpropionyl)amino]-propyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C30H38F3N3O5
|
1
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| 1 |
Ki = 10 nM
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CP0866162
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N-adamantan-1-ylmethyl-N-{2-[3-endo-(3-carbamoyl-phenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}succinamic acid trifluoroacetate salt
Show/Hide
|
C33H44F3N3O6
|
1
|
| 1 |
Ki = 10 nM
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CP0866163
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3-endo-(8-{2-[cyclohexylmethyl-(1-hydroxycyclopropanecarbonyl)-amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C29H40F3N3O5
|
1
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| 1 |
Ki = 10 nM
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CP0866164
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[(cyclohexylmethyl-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}carbamoyl)methanesulfonyl]acetic acid
Show/Hide
|
C26H38N2O6S
|
1
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| 1 |
Ki = 10 nM
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CP0867052
|
3-endo-(8-{2-[(2,6-difluorobenzyl)-(trans-4-hydroxy-cyclohexanecarbonyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)benzamide trifluoroacetate salt
Show/Hide
|
C32H38F5N3O5
|
1
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| 1 |
Ki = 10 nM
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CP0867053
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1-hydroxy-cyclopropanecarboxylic acid cyclohexylmethyl-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}amide
Show/Hide
|
C26H38N2O3
|
1
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| 1 |
Ki = 10 nM
|
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CP0867054
|
3-endo-{8-[2-(3-sec-butyl-1-cyclohexylmethyl-ureido)ethyl]-8-azabicyclo[3.2.1]oct-3-yl}benzamide
Show/Hide
|
C28H44N4O2
|
1
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| 1 |
Ki = 10 nM
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CP0867055
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2-hydroxy-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}-N-(4-trifluoromethylbenzyl)acetamide
Show/Hide
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C25H29F3N2O3
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1
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| 1 |
Ki = 10 nM
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CP0867056
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N-(2,6-difluorobenzyl)-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}-2-methanesulfonyl-acetamide
Show/Hide
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C25H30F2N2O4S
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1
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| 1 |
Ki = 10 nM
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CP0867057
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N-(2,6-difluorobenzyl)-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}-3-methylbutyramide
Show/Hide
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C27H34F2N2O2
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1
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| 1 |
Ki = 10 nM
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CP0867058
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1-cyclohexylmethyl-3-(3,4-dimethoxyphenyl)-1-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}urea
Show/Hide
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C31H43N3O4
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1
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| 1 |
Ki = 10 nM
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CP0867059
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3-endo-(8-{2-[benzyl-((R)-2,3-dihydroxypropionyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C28H34F3N3O6
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1
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| 1 |
Ki = 10 nM
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CP0867060
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3-endo-(8-{2-[cyclopentylmethyl-(3-hydroxy-2-hydroxymethyl-2-methyl-propionyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C29H42F3N3O6
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1
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| 1 |
Ki = 10 nM
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CP0867061
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3-endo-(8-{2-[(4-fluorocyclohexylmethyl)-((S)-2,3-dihydroxy-propionyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C28H39F4N3O6
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1
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| 1 |
Ki = 10 nM
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CP0867062
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3-endo-(8-{2-[(2,6-difluorobenzyl)-(2,2-dimethylpropionyl)amino]-ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide trifluoroacetate salt
Show/Hide
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C30H36F5N3O4
|
1
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| 1 |
Ki = 10 nM
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CP0867063
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cyclopropanecarboxylic acid(R)-benzyl-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]-1-methylethyl}amide
Show/Hide
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C27H34N2O2
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1
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| 1 |
Ki = 10 nM
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CP0867064
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N-(3-fluorobenzyl)-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo [3.2.1]oct-8-yl]ethyl}-3-methylbutyramide
Show/Hide
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C27H35FN2O2
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1
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| 1 |
Ki = 10 nM
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CP0867065
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3-benzo[1,3]dioxol-5-yl-1-cyclohexylmethyl-1-{2-[3-endo-(3-hydroxy-phenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}urea
Show/Hide
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C30H39N3O4
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1
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| 1 |
Ki = 10 nM
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CP0867066
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N-cyclohexylmethyl-N-{2-[3-endo-(3-hydroxy-phenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}malonamic acid
Show/Hide
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C25H36N2O4
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1
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| 1 |
Ki = 10 nM
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CP0867067
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N-cyclohexylmethyl-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}-2-phenylacetamide
Show/Hide
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C30H40N2O2
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1
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| 1 |
Ki = 10 nM
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CP0867117
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1-cyclohexylmethyl-3-(4-difluoromethoxyphenyl)-1-{2-[3-endo-(3-hydroxy-phenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}urea
Show/Hide
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C30H39F2N3O3
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1
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| 1 |
Ki = 10 nM
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CP0867118
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3-endo-(8-{2-[cyclopentylmethyl-(3-hydroxy-2,2-dimethylpropionyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C29H42F3N3O5
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1
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| 1 |
Ki = 10 nM
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CP0867119
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3-endo-(8-{2-[benzyl-(2-methoxyacetyl)-amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C28H34F3N3O5
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1
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| 1 |
Ki = 10 nM
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CP0867120
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3-endo-(8-{2-[(4,4-difluoro-cyclohexylmethyl)-(3-hydroxy-2-hydroxymethyl-2-methylpropionyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C30H42F5N3O6
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1
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| 1 |
Ki = 10 nM
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CP0867138
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3-endo-(8-{2-[cyclohexylmethyl-((R)-2,3-dihydroxy-propionyl)-amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide
Show/Hide
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C26H39N3O4
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1
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| 1 |
Ki = 10 nM
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CP0867139
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3-endo-(8-{2-[(3-fluorobenzyl)-(2-hydroxyacetyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C27H31F4N3O5
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1
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| 1 |
Ki = 10 nM
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CP0869129
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3-endo-(8-{2-[(3-fluorobenzyl)-(2-methanesulfonyl-acetyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C28H33F4N3O6S
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1
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| 1 |
Ki = 10 nM
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CP0869130
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3-endo-(8-{2-[(2-methanesulfonylacetyl)-(4-trifluoromethyl-benzyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C29H33F6N3O6S
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1
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| 1 |
Ki = 10 nM
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CP0869138
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3-endo-(8-{2-[(2-methanesulfonylacetyl)-(4-methyl-cyclohexylmethyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C29H42F3N3O6S
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1
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| 1 |
Ki = 10 nM
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CP0869170
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3-endo-(8-{2-[benzyl-(2,2-dimethylpropionyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C30H38F3N3O4
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1
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| 1 |
Ki = 10 nM
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CP0869171
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3-endo-(8-{2-[benzyl-(2-hydroxy-1-oxopropyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C28H34F3N3O5
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1
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| 1 |
Ki = 10 nM
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CP0869173
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3-endo-(8-{3-[benzyl-((S)-2-hydroxypropionyl)-amino]propyl}-8-azabicyclo [3.2.1]oct-3-yl)-benzamide
Show/Hide
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C27H35N3O3
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1
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| 1 |
Ki = 10 nM
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CP0869174
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3-endo-(8-{3-[benzyl-(2-hydroxyacetyl)amino]-propyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide
Show/Hide
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C26H33N3O3
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1
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| 1 |
Ki = 10 nM
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CP0869175
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3-endo-{8-[2-(acetyl-adamantan-1-ylmethylamino)ethyl]-8-azabicyclo[3.2.1]oct-3-yl}benzamide trifluoroacetate salt
Show/Hide
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C31H42F3N3O4
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1
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| 1 |
Ki = 10 nM
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CP0869176
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3-endo-(8-{2-[cyclohexylmethyl-(4-dimethylamino-butyryl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)benzamide
Show/Hide
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C29H46N4O2
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1
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| 1 |
Ki = 10 nM
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CP0869180
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3-endo-(8-{2-[cyclobutylmethyl-((R)-2,3-dihydroxypropionyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C26H36F3N3O6
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1
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| 1 |
Ki = 10 nM
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CP0869183
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3-endo-(8-{2-[(2-cyanoacetyl)-(2,6-difluorobenzyl)amino]ethyl}-8-aza-bicyclo [3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C28H29F5N4O4
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1
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| 1 |
Ki = 10 nM
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CP0869184
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3-endo-(8-{2-[(2,6-difluoro-benzyl)-((R)-2,3-dihydroxypropionyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)benzamide trifluoroacetate salt
Show/Hide
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C28H32F5N3O6
|
1
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| 1 |
Ki = 10 nM
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CP0869187
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(R)-2-cyclohexyl-N-cyclohexylmethyl-2-hydroxy-N-{2-[3-endo-(3-hydroxy-phenyl)-8-azabicyclo[3.2.1]oct-8-yl]-ethyl}acetamide
Show/Hide
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C30H46N2O3
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1
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| 1 |
Ki = 10 nM
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CP0869188
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(S)-N-cyclohexylmethyl-2-hydroxy-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}-3-phenyl-propionamide
Show/Hide
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C31H42N2O3
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1
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| 1 |
Ki = 10 nM
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CP0869386
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3-endo-(8-{2-[(2,6-difluorobenzyl)-(3-hydroxy-2,2-dimethylpropionyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)benzamide trifluoroacetate salt
Show/Hide
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C30H36F5N3O5
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1
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| 1 |
Ki = 10 nM
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CP0871116
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3-endo-(8-{2-[(cis-4-hydroxycyclohexylmethyl)-((S)-2,3-dihydroxypropionyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide
Show/Hide
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C26H39N3O5
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1
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| 1 |
Ki = 10 nM
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CP0871117
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3-endo-(8-{2-[(2-methanesulfonylacetyl)-(4-trifluoromethyl-cyclohexyl-methyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C29H39F6N3O6S
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1
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| 1 |
Ki = 10 nM
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CP0871118
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3-endo-(8-{2-[(4-fluorobenzyl)-(2-methanesulfonylacetyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C28H33F4N3O6S
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1
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| 1 |
Ki = 10 nM
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CP0871119
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3-endo-(8-{2-[benzyl-((R)-3-hydroxy-2-(S)-hydroxybutyryl)amino]-ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
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C29H36F3N3O6
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1
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| 1 |
Ki = 10 nM
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CP0871120
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3-endo-(8-{2-[cyclobutylmethyl-(2-hydroxyacetyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C25H34F3N3O5
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1
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| 1 |
Ki = 10 nM
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CP0871121
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3-endo-(8-{3-[benzyl-((R)-2,3-dihydroxypropionyl)amino]propyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C29H36F3N3O6
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1
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| 1 |
Ki = 10 nM
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CP0871233
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N-(2,6-difluorobenzyl)-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}malonamic acid
Show/Hide
|
C25H28F2N2O4
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1
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| 1 |
Ki = 10 nM
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CP0873083
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3-endo-(8-{3-[cyclohexylmethyl-(2-hydroxy-acetyl)amino]propyl}-8-azabicyclo[3.2.1]oct-3-yl)benzamide
Show/Hide
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C26H39N3O3
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1
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| 1 |
Ki = 10 nM
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CP0873086
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N-benzyl-2-ethyl-N-{(R)-2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]-1-methylethyl}butyramide
Show/Hide
|
C29H40N2O2
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1
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| 1 |
Ki = 10 nM
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CP0873087
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cyclohexanecarboxylic acid(R)-benzyl-{2-[3-endo-(3-hydroxy-phenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]-1-methyl-ethyl}-amide
Show/Hide
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C30H40N2O2
|
1
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| 1 |
Ki = 10 nM
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CP0873117
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3-endo-(8-{2-[(2-hydroxy-acetyl)(4-trifluoromethyl-cyclohexyl-methyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C28H37F6N3O5
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1
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| 1 |
Ki = 10 nM
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CP0875204
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1-cyclohexylmethyl-1-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}-3-pentylurea
Show/Hide
|
C28H45N3O2
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1
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| 1 |
Ki = 10 nM
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CP0875206
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3-benzyl-1-cyclohexylmethyl-1-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}urea
Show/Hide
|
C30H41N3O2
|
1
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| 1 |
Ki = 10 nM
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CP0875210
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3-endo-(8-{2-[((S)-4-tert-butylamino-2-hydroxy-butyryl)-cyclohexylmethyl-amino]-ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide
Show/Hide
|
C31H50N4O3
|
1
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| 1 |
Ki = 10 nM
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CP0888249
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3-endo-(8-{2-[(2,6-difluorobenzyl)-methanesulfonylamino]-ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C26H30F5N3O5S
|
1
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| 1 |
Ki = 10 nM
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CP0888250
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3-endo-(8-{2-[(2,6-difluorobenzyl)-(2-methoxyacetyl)-amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide trifluoroacetate salt
Show/Hide
|
C28H32F5N3O5
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1
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| 1 |
Ki = 10 nM
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CP0888251
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3-endo-(8-2-[cyclohexylmethyl-(S)-3,4-dihydroxybutyrylamino]ethyl-8-azabicyclo[3.2.1]oct-3-yl)benzamide trifluoroacetate salt
Show/Hide
|
C29H42F3N3O6
|
1
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| 1 |
Ki = 10 nM
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CP0888252
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3-endo-(8-{2-[cyclohexylmethyl-(4-hydroxy-butyryl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)benzamide
Show/Hide
|
C27H41N3O3
|
1
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| 1 |
Ki = 10 nM
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CP0888254
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3-endo-{8-[2-(3-benzo[1,3]dioxol-5-yl-1-cyclohexylmethylureido)ethyl]-8-azabicyclo[3.2.1]oct-3-yl}benzamide
Show/Hide
|
C31H40N4O4
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1
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| 1 |
Ki = 10 nM
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CP0895917
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1-[(cyclohexylmethyl-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}carbamoyl)methyl]cyclohexyl-acetic acid
Show/Hide
|
C32H48N2O4
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1
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| 1 |
Ki = 10 nM
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CP0895918
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1-cyclohexylmethyl-3-(4-fluorobenzyl)-1-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}urea
Show/Hide
|
C30H40FN3O2
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1
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| 1 |
Ki = 10 nM
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CP0901796
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2-(cyclohexylmethyl-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]-ethyl}carbamoyl)cyclohexanecarboxylic acid
Show/Hide
|
C30H44N2O4
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1
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| 1 |
Ki = 10 nM
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CP0903452
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3-endo-(8-(2-((4-fluoromethylbenzyl)(N,N-dimethylsulfamoyl)-amino)ethyl)-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C28H36F4N4O5S
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1
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| 1 |
Ki = 10 nM
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CP0905624
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3-endo-(8-{2-[((S)-2,3-dihydroxypropionyl)phenethylamino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C29H36F3N3O6
|
1
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| 1 |
Ki = 10 nM
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CP0905625
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3-endo-(8-{2-[cyclohexylmethyl-(3-dimethylamino-2-hydroxypropionyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)benzamide
Show/Hide
|
C28H44N4O3
|
1
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| 1 |
Ki = 10 nM
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CP0905626
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N-benzyl-N-{(R)-2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]-1-methylethyl}acetamide
Show/Hide
|
C25H32N2O2
|
1
|
| 1 |
Ki = 10 nM
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CP0906040
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3-endo-{8-[2-(cyclohexylmethyl-phenylacetylamino)-ethyl]-8-azabicyclo[3.2.1]oct-3-yl}benzamide
Show/Hide
|
C31H41N3O2
|
1
|
| 1 |
Ki = 10 nM
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CP0911123
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N-benzyl-N-{(R)-2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]-1-methyl-ethyl}-2-phenylacetamide
Show/Hide
|
C31H36N2O2
|
1
|
| 1 |
Ki = 10 nM
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CP0913574
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N-cyclohexylmethyl-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}-3-methylbutyramide
Show/Hide
|
C27H42N2O2
|
1
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| 1 |
Ki = 10 nM
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CP0913575
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{1-[(cyclohexylmethyl-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]-ethyl}carbamoyl)methyl]cyclopentyl}acetic acid
Show/Hide
|
C31H46N2O4
|
1
|
| 1 |
Ki = 10 nM
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CP0913922
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N-benzyl-N-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]-ethyl}succinamic acid methylester
Show/Hide
|
C27H34N2O4
|
1
|
| 1 |
Ki = 10 nM
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CP0913924
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3-endo-(8-{2-[(2,6-difluorobenzyl)-(2-methanesulfonylacetyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide
Show/Hide
|
C26H31F2N3O4S
|
1
|
| 1 |
Ki = 10 nM
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CP0913925
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N-(4-chlorobenzyl)-2-hydroxy-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}acetamide
Show/Hide
|
C24H29ClN2O3
|
1
|
| 1 |
Ki = 10 nM
|
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CP0913926
|
N-(3-fluorobenzyl)-N-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]-ethyl}malonamic acid
Show/Hide
|
C25H29FN2O4
|
1
|
| 1 |
Ki = 10 nM
|
|
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CP0913927
|
N-cyclohexylmethyl-N-{2-[3-endo-(3-hydroxy-phenyl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}succinamide
Show/Hide
|
C26H39N3O3
|
1
|
| 1 |
Ki = 10 nM
|
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CP0913928
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3-endo-(8-{2-[(2,6-difluorobenzyl)-((S)-2-hydroxypropionyl)amino]-ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide trifluoroacetate salt
Show/Hide
|
C28H32F5N3O5
|
1
|
| 1 |
Ki = 10 nM
|
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CP0913930
|
N-adamantan-1-ylmethyl-2-hydroxy-N-{2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]-ethyl}acetamide trifluoroacetate salt
Show/Hide
|
C30H41F3N2O5
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0914975
|
N-cyclohexylmethyl-2-hydroxy-N-{2-[3-endo-(3-methanesulfonylamino-phenyl)-8-azabicyclo[3.2.1]oct-8-yl]-ethyl}acetamide
Show/Hide
|
C25H39N3O4S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0915436
|
3-endo-{8-[2-(cyclopentylmethyl-methanesulfonylamino)ethyl]-8-aza-bicyclo[3.2.1]oct-3-yl}-benzamide trifluoroacetate salt
Show/Hide
|
C25H36F3N3O5S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0915437
|
3-endo-(8-{2-[benzyl-(2-cyanoacetyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C28H31F3N4O4
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0915439
|
(R)-N-cyclohexylmethyl-2-hydroxy-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}-4-phenyl-butyramide
Show/Hide
|
C32H44N2O3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0915440
|
N-benzyl-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}acetamide
Show/Hide
|
C24H30N2O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0915650
|
3-endo-(8-{2-[(2,6-difluorobenzyl)-((S)-2-hydroxy-3-phenylpropionyl)-amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide trifluoroacetate salt
Show/Hide
|
C34H36F5N3O5
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0921753
|
3-endo-(8-{2-[(4,4-difluorocyclohexylmethyl)-(2-methanesulfonylacetyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C28H38F5N3O6S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0921754
|
3-endo-(8-{3-[benzyl-((S)-2,3-dihydroxypropionyl)amino]propyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C29H36F3N3O6
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0921757
|
3-endo-(8-{2-[cyclopentylmethyl-(2-methanesulfonylacetyl)-amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C27H38F3N3O6S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0922627
|
3-endo-(8-{2-[(4,4-difluorocyclohexylmethyl)-((S)-2,3-dihydroxy-propionyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C28H38F5N3O6
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0930853
|
3-endo-(8-{2-[(2-aminoacetyl)-cyclohexylmethyl-amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)benzamide
Show/Hide
|
C25H38N4O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0932749
|
3-endo-(8-{2-[benzyl-((S)-2,3-dihydroxypropionyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C28H34F3N3O6
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0933008
|
3-endo-(8-{2-[cyclohexylmethyl-(3-hydroxy-2-hydroxymethyl-2-methylpropionyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide
Show/Hide
|
C28H43N3O4
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0943857
|
3-endo-(8-{2-[cyclohexylmethyl-((S)-3-hydroxy-2-methylamino-propionyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide bis trifluoroacetate salt
Show/Hide
|
C31H44F6N4O7
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0945319
|
3-endo-(8-(2-((2,6-difluorobenzyl)(N,N-dimethylsulfamoyl)amino)ethyl)-8-azabicyclo[3.2.1]oct-3-yl)benzamide trifluoroacetate salt
Show/Hide
|
C27H33F5N4O5S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0945320
|
N-benzyl-N-{(R)-2-[3-endo-(3-hydroxyphenyl)-8-azabicyclo[3.2.1]oct-8-yl]-1-methyl-ethyl}-3-methylbutyramide
Show/Hide
|
C28H38N2O2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0947359
|
3-endo-(8-2-[cyclohexylmethyl-((S)-2,4-dihydroxybutyryl)amino]ethyl-8-azabicyclo[3.2.1]oct-3-yl)benzamide trifluoroacetate salt
Show/Hide
|
C29H42F3N3O6
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0947360
|
N-cyclohexylmethyl-2-hydroxy-N-{2-[3-endo-(3-hydroxyphenyl)-8-aza-bicyclo[3.2.1]oct-8-yl]ethyl}-4-phenyl-butyramide
Show/Hide
|
C32H44N2O3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0947361
|
3-endo-(8-{3-[cyclohexylmethyl-(2-methanesulfonyl-acetyl)amino]propyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzamide
Show/Hide
|
C27H41N3O4S
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0949616
|
3-endo-(8-{2-[benzyl-(3-hydroxy-2,2-dimethylpropionyl)amino]ethyl}-8-aza-bicyclo[3.2.1]oct-3-yl)-benzamide trifluoroacetate salt
Show/Hide
|
C30H38F3N3O5
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0949617
|
3-endo-(8-{2-[cyclohexylmethyl-(3-hydroxy-2,2-dimethyl-propionyl)-amino]-ethyl}-8-azabicyclo[3.2.1]oct-3-yl)benzamide
Show/Hide
|
C28H43N3O3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0949618
|
(S)-2-cyclohexyl-N-cyclohexylmethyl-2-hydroxy-N-{2-[3-endo(3-hydroxy-phenyl)-8-azabicyclo[3.2.1]oct-8-yl]-ethyl}acetamide
Show/Hide
|
C30H46N2O3
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0386134
|
1-[1-(1-methylcyclooctyl)piperidin-4-yl]-1H-benzimidazole
Show/Hide
|
C21H31N3
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0463349
|
2-(3-(1-cyclodecylpiperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide
Show/Hide
|
C25H38N4O2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0910087
|
trans-N1,N1-dimethyl-N4-phenethyl-1-phenylcyclohexane-1,4-diamine dihydrochloride
Show/Hide
|
C22H32Cl2N2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0159328
|
3-((1R,2R)-2-((dimethylamino)methyl)-1-hydroxycyclohexyl)phenol
Show/Hide
|
C15H23NO2
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0498922
|
2-{1-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-benzo[1,2,6]thiadiazin-3-yl}-N-methyl-acetamide
Show/Hide
|
C24H38N4O3S
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0868691
|
trans-4-(benzyloxy)-N,N-dimethyl-1-phenylcyclohexanamine hydrochloride
Show/Hide
|
C21H28ClNO
|
1
|
| 1 |
Ki = 12 nM
|
|
|
|
CP0536345
|
3-[(1R,5S)-8-[2-[(2-hydroxyacetyl)-(oxan-4-ylmethyl)amino]ethyl]-8-azabicyclo[3.2.1]octan-3-yl]benzamide
Show/Hide
|
C24H35N3O4
|
1
|
| 1 |
Ki = 12.59 nM
|
|
|
|
CP0462665
|
2-(4,5-dimethoxy-2-pyrrolidin-1-ylsulfonylphenyl)-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
Show/Hide
|
C27H37N3O5S
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0469633
|
2-{1-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-2,2-dioxo-1,4-dihydro-2H-2lambda*6*-benzo[1,2,6]thiadiazin-3-yl}-N-methyl-acetamide
Show/Hide
|
C25H38N4O3S
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0917578
|
US9120797, 36
Show/Hide
|
C26H32N2O
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0945402
|
US9120797, 16
Show/Hide
|
C25H29BrN2O
|
1
|
| 1 |
Ki = 14 nM
|
|
|
|
CP0436366
|
2-(4,5-dimethoxy-2-morpholin-4-ylsulfonylphenyl)-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
Show/Hide
|
C27H37N3O6S
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0478127
|
US9120797, 29
Show/Hide
|
C25H31N3
|
1
|
| 1 |
Ki = 15 nM
|
|
|
|
CP0136050
|
2-{8-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-4-oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-3-yl}-N-methyl-acetamide
Show/Hide
|
C30H42N4O4
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0542477
|
methyl 2-[[(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,7,9-trihydroxy-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-6-carbonyl]amino]-2-methylpropanoate
Show/Hide
|
C26H32N2O7
|
1
|
| 1 |
Ki = 16.5 nM
|
|
|
|
CP0443837
|
US9120797, 31
Show/Hide
|
C24H28FN3
|
1
|
| 1 |
Ki = 17 nM
|
|
|
|
CP0542476
|
(1S,2S,13R,21R)-22-(cyclopropylmethyl)-2,16-dihydroxy-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-8-carboxylic acid
Show/Hide
|
C27H26N2O5
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0489674
|
N-methyl-2-[1-[1-[(4-methylnaphthalen-1-yl)methyl]piperidin-4-yl]-2-oxo-4H-quinazolin-3-yl]acetamide
Show/Hide
|
C28H32N4O2
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0406771
|
US9120797, 44
Show/Hide
|
C24H27BrN2O
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0477171
|
(1S,2S,13R,21R)-9-chloro-22-(cyclopropylmethyl)-2,16-dihydroxy-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15,17,19(25)-heptaene-8-carboxylic acid
Show/Hide
|
C27H25ClN2O5
|
1
|
| 1 |
Ki = 19 nM
|
|
|
|
CP0396710
|
(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,7,9-trihydroxy-N-[(2R)-1-hydroxypropan-2-yl]-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-6-carboxamide
Show/Hide
|
C24H30N2O6
|
1
|
| 1 |
Ki = 19.4 nM
|
|
|
|
CP0435079
|
2-[2-[benzyl(methyl)sulfamoyl]-4,5-dimethoxyphenyl]-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
Show/Hide
|
C31H39N3O5S
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0497582
|
2-(1-(1-(4-isopropylcyclohexyl)piperidin-4-yl)-2-oxo-1,2-dihydroquinazolin-3(4H)-yl)-N-methylacetamide
Show/Hide
|
C25H38N4O2
|
1
|
| 1 |
Ki = 21 nM
|
|
|
|
CP0868692
|
trans-N1,N1-dimethyl-1-phenyl-N4-(3-phenylpropyl)cyclohexane-1,4-diamine dihydrochloride
Show/Hide
|
C23H34Cl2N2
|
1
|
| 1 |
Ki = 22 nM
|
|
|
|
CP0051440
|
1-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-3-methylsulfanylmethyl-1,3-dihydro-benzimidazol-2-one
Show/Hide
|
C28H39N3O3S
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0477172
|
(1S,2S,9R,17R)-18-(cyclopropylmethyl)-5-methyl-10-oxa-6,7,18-triazahexacyclo[9.9.1.01,9.02,17.04,8.015,21]henicosa-4(8),5,11,13,15(21)-pentaene-2,12-diol
Show/Hide
|
C22H25N3O3
|
1
|
| 1 |
Ki = 24 nM
|
|
|
|
CP0399638
|
2-[2-(dimethylsulfamoyl)-4,5-dimethoxyphenyl]-N-[(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl]-N-methylacetamide
Show/Hide
|
C25H35N3O6S
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0335783
|
1-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-3-(2-methylsulfanyl-ethyl)-1,3-dihydro-benzimidazol-2-one
Show/Hide
|
C29H41N3O3S
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0436368
|
2-[4,5-dimethoxy-2-(4-methylpiperazin-1-yl)sulfonylphenyl]-N-[(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl]-N-methylacetamide
Show/Hide
|
C28H40N4O6S
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0463351
|
2-(1'-cyclodecyl-2-oxospiro[benzo[d][1,3]oxazine-4,4'-piperidine]-1(2H)-yl)-N-methylacetamide
Show/Hide
|
C25H37N3O3
|
1
|
| 1 |
Ki = 27 nM
|
|
|
|
CP0441047
|
(2S)-N,N-dimethyl-1-[3-(8-phenyl-3-azabicyclo[3.2.1]octan-3-yl)propanoyl]-2,3-dihydroindole-2-carboxamide
Show/Hide
|
C27H33N3O2
|
1
|
| 1 |
Ki = 28.4 nM
|
|
|
|
CP0481417
|
1-[3-[4-(2-ethoxyphenyl)piperazin-1-yl]propanoyl]-N,N-dimethyl-2,3-dihydroindole-2-carboxamide
Show/Hide
|
C26H34N4O3
|
1
|
| 1 |
Ki = 29.8 nM
|
|
|
|
CP0500235
|
2-(3-(1-((1r,4r)-4-isopropylcyclohexyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide
Show/Hide
|
C24H36N4O2
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0485881
|
1-[8-(dimethylamino)-8-phenyl-2-azaspiro[4.5]decan-2-yl]butan-1-one
Show/Hide
|
C21H32N2O
|
1
|
| 1 |
Ki = 30.5 nM
|
|
|
|
CP0145418
|
8-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
Show/Hide
|
C27H37N3O3
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0436371
|
2-[6-(dimethylsulfamoyl)-1,3-benzodioxol-5-yl]-N-[(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl]-N-methylacetamide
Show/Hide
|
C24H31N3O6S
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0489530
|
N-methyl-2-[2-oxo-3-(1-spiro[5.5]undecan-4-ylpiperidin-4-yl)benzimidazol-1-yl]acetamide
Show/Hide
|
C26H38N4O2
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0435080
|
2-[2-(dimethylsulfamoyl)-4,5-dimethoxyphenyl]-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
Show/Hide
|
C25H35N3O5S
|
1
|
| 1 |
Ki = 42 nM
|
|
|
|
CP0521467
|
4-(dimethylamino)-1,4-diphenylcyclohexan-1-ol
Show/Hide
|
C20H25NO
|
1
|
| 1 |
Ki = 44.5 nM
|
|
|
|
CP0221376
|
1-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-3-(2-methylamino-ethyl)-1,3-dihydro-benzimidazol-2-one
Show/Hide
|
C29H42N4O3
|
1
|
| 1 |
Ki = 46 nM
|
|
|
|
CP0858238
|
Cis-6'-Fluoro-4',9'-dihydro-N,N-dimethyl-4-phenyl-spiro[cyclohexane-1,1'(3'H)-pyrano[3,4-b]indol]-4-amine Hemicitrate
Show/Hide
|
C30H35FN2O8
|
1
|
| 1 |
Ki = 46 nM
|
|
|
|
CP0432948
|
2-[[(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,7,9-trihydroxy-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-6-carbonyl]amino]-2-methylpropanoic acid
Show/Hide
|
C25H30N2O7
|
1
|
| 1 |
Ki = 46.1 nM
|
|
|
|
CP0478166
|
2-[6-(dimethylsulfamoyl)-1,3-benzodioxol-5-yl]-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
Show/Hide
|
C24H31N3O5S
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0504638
|
N-methyl-2-[2-oxo-3-[1-(2,2,4,4-tetramethylcyclohexyl)piperidin-4-yl]benzimidazol-1-yl]acetamide
Show/Hide
|
C25H38N4O2
|
1
|
| 1 |
Ki = 47 nM
|
|
|
|
CP0921140
|
1'-{(3,4-dihydro-2H-chromen-3-yl)methyl}-2,3-dihydro-1'H-spiro[indene-1,4'-piperidine]
Show/Hide
|
C23H27NO
|
1
|
| 1 |
Ki = 49.1 nM
|
|
|
|
CP0509939
|
2-[4,5-dimethoxy-2-(4-methylpiperazin-1-yl)sulfonylphenyl]-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
Show/Hide
|
C28H40N4O5S
|
1
|
| 1 |
Ki = 52 nM
|
|
|
|
CP0049540
|
(S)-2-(3,4-Dichloro-phenyl)-N-methyl-N-(1-phenyl-2-pyrrolidin-1-yl-ethyl)-acetamide(ICI 199441)
Show/Hide
|
C21H24Cl2N2O
|
1
|
| 1 |
Ki = 53 nM
|
|
|
|
CP0512066
|
US9120797, 52
Show/Hide
|
C24H26FNOS2
|
1
|
| 1 |
Ki = 58 nM
|
|
|
|
CP0389454
|
1'-[(2-methyl-3,4-dihydro-1H-isoquinolin-3-yl)methyl]spiro[1,2-dihydroindene-3,4'-piperidine]
Show/Hide
|
C24H30N2
|
1
|
| 1 |
Ki = 58.2 nM
|
|
|
|
CP0915677
|
US9120797, 35
Show/Hide
|
C25H29FN2O
|
1
|
| 1 |
Ki = 61 nM
|
|
|
|
CP0051361
|
1-(2-hydroxy-ethyl)-3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydrobenzimidazol-2-one
Show/Hide
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C28H39N3O4
|
1
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| 1 |
Ki = 62 nM
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CP0506549
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N-methyl-2-[3-[1-(naphthalen-1-ylmethyl)piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetamide
Show/Hide
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C26H28N4O2
|
1
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| 1 |
Ki = 67 nM
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CP0481420
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(2S)-N,N-dimethyl-1-[3-[4-(2-methylphenyl)piperidin-1-yl]propanoyl]-2,3-dihydroindole-2-carboxamide
Show/Hide
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C26H33N3O2
|
1
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| 1 |
Ki = 67.2 nM
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CP0380262
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5-chloro-3-(spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylmethyl)-1,2,3,4-tetrahydroisoquinolin-8-ol
Show/Hide
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C23H27ClN2O
|
1
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| 1 |
Ki = 68.8 nM
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CP0364199
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2-(3-(1-((1s,4s)-4-isopropylcyclohexyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide
Show/Hide
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C24H36N4O2
|
1
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| 1 |
Ki = 69 nM
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CP0338887
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1-methanesulfonylmethyl-3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one
Show/Hide
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C28H39N3O5S
|
1
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| 1 |
Ki = 70 nM
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CP0486900
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1-[3-(spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylmethyl)-3,4-dihydro-1H-isoquinolin-2-yl]ethanone
Show/Hide
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C25H30N2O
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1
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| 1 |
Ki = 74.4 nM
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CP0399718
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N-(2-hydroxyethyl)-2-[3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetamide
Show/Hide
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C30H42N4O5
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1
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| 1 |
Ki = 75 nM
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CP0489528
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2-(3-(1-(4-tert-butylcyclohexyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide
Show/Hide
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C25H38N4O2
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1
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| 1 |
Ki = 77 nM
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CP0452286
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(2S)-N,N-dimethyl-1-[3-(4-phenylpiperidin-1-yl)propanoyl]-2,3-dihydroindole-2-carboxamide
Show/Hide
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C25H31N3O2
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1
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| 1 |
Ki = 80.7 nM
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CP0502924
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(2S)-1-[3-[4-(2,6-dimethylphenyl)piperidin-1-yl]propanoyl]-N,N-dimethyl-2,3-dihydroindole-2-carboxamide
Show/Hide
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C27H35N3O2
|
1
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| 1 |
Ki = 82.1 nM
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CP0391100
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(4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,7,9-trihydroxy-N-[1-(methanesulfonamido)-2-methyl-1-oxopropan-2-yl]-1,2,4,5,7a,13-hexahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-6-carboxamide
Show/Hide
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C26H33N3O8S
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1
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| 1 |
Ki = 93.6 nM
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CP0371949
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N-(cyclopropylmethyl)-2-[3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetamide
Show/Hide
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C32H44N4O4
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1
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| 1 |
Ki = 100 nM
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CP0124715
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N-(4-amino-2-methylquinolin-6-yl)-2-[(4-ethylphenoxy)methyl]benzamide
Show/Hide
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C26H25N3O2
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1
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| 1 |
Ki = 102.9 nM
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CP0221377
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2-[3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]ethyl acetate
Show/Hide
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C30H41N3O5
|
1
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| 1 |
Ki = 103 nM
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CP0157527
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1-(2-dimethylamino-ethyl)-3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one
Show/Hide
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C30H44N4O3
|
1
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| 1 |
Ki = 106 nM
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CP0411109
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2-[3-(1-Cyclodecyl-piperidin-4-yl)-2,2-dioxo-2,3-dihydro-2lambda*6*-benzo[1,2,5]thiadiazol-1-yl]-N-methyl-acetamide
Show/Hide
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C24H38N4O3S
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1
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| 1 |
Ki = 107 nM
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CP0444889
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N-cyclobutyl-2-[3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetamide
Show/Hide
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C32H44N4O4
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1
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| 1 |
Ki = 108 nM
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CP0497282
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2-(1'-(4-isopropylcyclohexyl)-2-oxospiro[benzo[d][1,3]oxazine-4,4'-piperidine]-1(2H)-yl)-N-methylacetamide
Show/Hide
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C24H35N3O3
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1
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| 1 |
Ki = 108 nM
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CP0859497
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2-[3-{(spiro[indane-1,4'-piperidin]-1'-yl)methyl}-3,4-dihydroisoquinolin-2(1H)-yl]acetamide
Show/Hide
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C24H29N3O
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1
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| 1 |
Ki = 108 nM
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CP0145420
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1-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-3-(2-oxo-butyl)-1,3-dihydro-benzimidazol-2-one
Show/Hide
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C30H41N3O4
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1
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| 1 |
Ki = 113 nM
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CP0469634
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2-(1'-(4-tert-butylcyclohexyl)-2-oxospiro[benzo[d][1,3]oxazine-4,4'-piperidine]-1(2H)-yl)-N-methylacetamide
Show/Hide
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C25H37N3O3
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1
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| 1 |
Ki = 113 nM
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CP0464210
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N-cyclopropyl-2-[3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetamide
Show/Hide
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C31H42N4O4
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1
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| 1 |
Ki = 119 nM
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CP0463345
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2-(3-(1-((4-methoxynaphthalen-1-yl)methyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide
Show/Hide
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C27H30N4O3
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1
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| 1 |
Ki = 120 nM
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CP0371609
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3-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-N-methyl-propionamide
Show/Hide
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C30H42N4O4
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1
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| 1 |
Ki = 122 nM
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CP0296905
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1-methanesulfinylmethyl-3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one
Show/Hide
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C28H39N3O4S
|
1
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| 1 |
Ki = 125 nM
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CP0498942
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2-(3-(1-(decahydronaphthalen-2-yl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide
Show/Hide
|
C25H36N4O2
|
1
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| 1 |
Ki = 127 nM
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CP0377805
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[1-[4-[2-(2-benzyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl)benzimidazol-1-yl]piperidin-1-yl]cyclooctyl]methanol
Show/Hide
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C34H47N5O
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1
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| 1 |
Ki = 128 nM
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CP0484873
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(2S)-1-[(2S)-2-(2-aminodecanoylamino)-3-(4-hydroxyphenyl)propanoyl]-N-[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
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C57H80N10O9S
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1
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| 1 |
Ki = 132 nM
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CP0296906
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2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-acetamide
Show/Hide
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C28H38N4O4
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1
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| 1 |
Ki = 138 nM
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CP0506548
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N-methyl-2-[3-[1-[(4-methylnaphthalen-1-yl)methyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetamide
Show/Hide
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C27H30N4O2
|
1
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| 1 |
Ki = 138 nM
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CP0920426
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N,N-Dimethyl-1-[3-(4-o-tolylpiperidin-1-yl)propanoyl]indoline-(2RS)-2-carboxamide
Show/Hide
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C26H33N3O2
|
1
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| 1 |
Ki = 138 nM
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CP0441036
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(2S)-1-[3-[4-(4-fluoro-2-methylphenyl)piperidin-1-yl]propanoyl]-N,N-dimethyl-2,3-dihydroindole-2-carboxamide
Show/Hide
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C26H32FN3O2
|
1
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| 1 |
Ki = 139 nM
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CP0866727
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5-bromo-3-{(2,3-dihydro-1'H-spiro[indene-1,4'-piperidin]-1'-yl)methyl}-1,2,3,4-tetrahydroisoquinolin-8-ol
Show/Hide
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C23H27BrN2O
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1
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| 1 |
Ki = 139 nM
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CP0372512
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(+)-Methyl(1S,2R,5R)-8-[2-(3,4-Dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonane-6-carboxylate
Show/Hide
|
C21H27Cl2N3O3
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1
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| 1 |
Ki = 140 nM
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CP0421844
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N-butyl-2-[3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetamide
Show/Hide
|
C32H46N4O4
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1
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| 1 |
Ki = 161 nM
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CP0460621
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2-butyl-8-(dimethylamino)-8-thiophen-2-yl-2-azaspiro[4.5]decan-1-one
Show/Hide
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C19H30N2OS
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1
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| 1 |
Ki = 170 nM
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CP0051438
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1-[2-(benzyl-methyl-amino)-ethyl]-3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methyl-pentyl]-piperidin-4-yl}-1,3-dihydro-benzimidazol-2-one
Show/Hide
|
C36H48N4O3
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1
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| 1 |
Ki = 172 nM
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CP0426963
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N-(2-methoxyethyl)-2-[3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetamide
Show/Hide
|
C31H44N4O5
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1
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| 1 |
Ki = 180 nM
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CP0417979
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(+)-1-[(1S,2S,5R)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonan-8-yl]-2-(3,4-dichlorophenyl)ethanone
Show/Hide
|
C26H31Cl2N3O
|
1
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| 1 |
Ki = 180 nM
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CP0371610
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2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-N,N-dimethyl-acetamide
Show/Hide
|
C30H42N4O4
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1
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| 1 |
Ki = 188 nM
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CP0371958
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2-[3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]-N-prop-2-enylacetamide
Show/Hide
|
C31H42N4O4
|
1
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| 1 |
Ki = 199 nM
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CP0945715
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2-(3-(1-(4-isopropylcyclohexyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide
Show/Hide
|
C24H36N4O2
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1
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| 1 |
Ki = 201 nM
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CP0386093
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1'-(1,2,3,4-tetrahydroisoquinolin-3-ylmethyl)spiro[1,2-dihydroindene-3,4'-piperidine]
Show/Hide
|
C23H28N2
|
1
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| 1 |
Ki = 225 nM
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CP0376884
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(1-{4-[2-(4-Methylpiperazin-1-yl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclooctyl)methanol
Show/Hide
|
C26H41N5O
|
1
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| 1 |
Ki = 229 nM
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CP0549303
|
8-benzyl-2-butyl-8-(dimethylamino)-2-azaspiro[4.5]decan-1-one
Show/Hide
|
C22H34N2O
|
1
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| 1 |
Ki = 230 nM
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CP0401625
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2-methyl-3-(spiro[1,2-dihydroindene-3,4'-piperidine]-1'-ylmethyl)-3,4-dihydroisoquinolin-1-one
Show/Hide
|
C24H28N2O
|
1
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| 1 |
Ki = 231 nM
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CP0443603
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N,N-dimethyl-1-[3-(4-pyrazin-2-ylpiperazin-1-yl)propanoyl]-2,3-dihydroindole-2-carboxamide
Show/Hide
|
C22H28N6O2
|
1
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| 1 |
Ki = 235 nM
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CP0490616
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2-[3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]-N-propan-2-ylacetamide
Show/Hide
|
C31H44N4O4
|
1
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| 1 |
Ki = 238 nM
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CP0526255
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(2S)-1-[3-[4-(4-fluorophenyl)piperidin-1-yl]propanoyl]-N,N-dimethyl-2,3-dihydroindole-2-carboxamide
Show/Hide
|
C25H30FN3O2
|
1
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| 1 |
Ki = 238 nM
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CP0399720
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N-tert-butyl-2-[3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetamide
Show/Hide
|
C32H46N4O4
|
1
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| 1 |
Ki = 245 nM
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CP0432046
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N,N-diethyl-4-[[(1R,5R)-4-phenyl-8-prop-2-enyl-6,8-diazabicyclo[3.2.2]non-3-en-6-yl]methyl]benzamide
Show/Hide
|
C28H35N3O
|
1
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| 1 |
Ki = 250 nM
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CP0422074
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2-{3-[1-(Decahydro-naphthalen-2-yl)-piperidin-4-yl]-2,2-dioxo-2,3-dihydro-2lambda*6*-benzo[1,2,5]thiadiazol-1-yl}-N-methyl-acetamide
Show/Hide
|
C24H36N4O3S
|
1
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| 1 |
Ki = 268 nM
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CP0847939
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N-[(1R,2S)-2-({2-[(4-Chlorophenyl)carbonyl]amino-6-methylquinazolin-4-yl}amino)cyclohexyl]guanidine dihydrochloride
Show/Hide
|
C23H29Cl4N7O
|
1
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| 1 |
Ki = 270 nM
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CP0309392
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(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-acetic acid methyl ester
Show/Hide
|
C29H39N3O5
|
1
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| 1 |
Ki = 271 nM
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CP0332957
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3-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-propionic acid methyl ester
Show/Hide
|
C30H41N3O5
|
1
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| 1 |
Ki = 271 nM
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CP0505592
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2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-N-propyl-acetamide
Show/Hide
|
C31H44N4O4
|
1
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| 1 |
Ki = 272 nM
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CP0469635
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2-(3-(1-(4,4-dimethylcyclohexyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide
Show/Hide
|
C23H34N4O2
|
1
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| 1 |
Ki = 282 nM
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CP0852726
|
3-{(2,3-dihydro-1'H-spiro[indene-1,4'-piperidin]-1'-yl)methyl}-1,2,3,4-tetrahydroisoquinolin-8-ol
Show/Hide
|
C23H28N2O
|
1
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| 1 |
Ki = 288 nM
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CP0371947
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N-ethyl-2-[3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetamide
Show/Hide
|
C30H42N4O4
|
1
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| 1 |
Ki = 289 nM
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CP0851049
|
1'-[(1,2,3,4-tetrahydronaphthalen-2-yl)methyl]-2,3-dihydro-1'H-spiro[indene-1,4'-piperidine]
Show/Hide
|
C24H29N
|
1
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| 1 |
Ki = 289 nM
|
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CP0858415
|
N-[(1RS,2SR)-2-({2-[(4-Chlorophenyl)carbonyl]amino-6-methylquinazolin-4-yl}amino)cyclohexyl]guanidine dihydrochloride
Show/Hide
|
C23H29Cl4N7O
|
1
|
| 1 |
Ki = 310 nM
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CP0858425
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cis-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4-b]indol]-4-amine hydrochloride
Show/Hide
|
C24H29ClN2O
|
1
|
| 1 |
Ki = 310 nM
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CP0526254
|
N,N-dimethyl-1-[3-[4-(2-methylphenyl)piperazin-1-yl]propanoyl]-2,3-dihydroindole-2-carboxamide
Show/Hide
|
C25H32N4O2
|
1
|
| 1 |
Ki = 318 nM
|
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CP0847927
|
N-[(1S,2R)-2-({2-[(4-Chlorophenyl)carbonyl]amino-6-methylquinazolin-4-yl}amino)cyclohexyl]guanidine dihydrochloride
Show/Hide
|
C23H29Cl4N7O
|
1
|
| 1 |
Ki = 330 nM
|
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CP0504915
|
3-[[4-(4-fluoro-2-methylphenyl)piperidin-1-yl]methyl]-1,2,3,4-tetrahydroisoquinoline
Show/Hide
|
C22H27FN2
|
1
|
| 1 |
Ki = 342 nM
|
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CP0463344
|
2-{3-[1-(4-Isopropyl-cyclohexyl)-piperidin-4-yl]-2,2-dioxo-2,3-dihydro-2lambda*6*-benzo[1,2,5]thiadiazol-1-yl}-N-methyl-acetamide
Show/Hide
|
C23H36N4O3S
|
1
|
| 1 |
Ki = 346 nM
|
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CP0463347
|
2-(3-(1-(2,2-dimethylcyclopentyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide
Show/Hide
|
C22H32N4O2
|
1
|
| 1 |
Ki = 350 nM
|
|
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CP0848412
|
3-{(2,3-Dihydro-1'H-spiro[indene-1,4'-piperidin]-1'-yl)methyl}-1,2,3,4-tetrahydroisoquinolin-6-ol
Show/Hide
|
C23H28N2O
|
1
|
| 1 |
Ki = 392 nM
|
|
|
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CP0443601
|
N,N-dimethyl-1-[3-(4-phenylpiperazin-1-yl)propanoyl]-2,3-dihydroindole-2-carboxamide
Show/Hide
|
C24H30N4O2
|
1
|
| 1 |
Ki = 397 nM
|
|
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CP0382639
|
N-benzyl-2-[3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetamide
Show/Hide
|
C35H44N4O4
|
1
|
| 1 |
Ki = 432 nM
|
|
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CP0436370
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2-(1,3-benzodioxol-5-yl)-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
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C22H26N2O3
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1
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| 1 |
Ki = 450 nM
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CP0390918
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(+)-1-[(1S,2R,5R)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonan-8-yl]-2-(3,4-dichlorophenyl)ethanone
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C26H31Cl2N3O
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1
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| 1 |
Ki = 470 nM
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CP0489089
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N,N-dimethyl-1-[3-(4-phenylpiperidin-1-yl)propanoyl]-2,3-dihydroindole-2-carboxamide
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C25H31N3O2
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1
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| 1 |
Ki = 502 nM
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CP0500259
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2-(1'-cycloheptyl-2-oxospiro[benzo[d][1,3]oxazine-4,4'-piperidine]-1(2H)-yl)-N-methylacetamide
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C22H31N3O3
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1
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| 1 |
Ki = 527 nM
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CP0498944
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2-(3-(1-cyclooctylpiperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide
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C23H34N4O2
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1
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| 1 |
Ki = 608 nM
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CP0437956
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3-[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethylpiperidin-1-yl]propanoic acid
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C16H23NO3
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1
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| 1 |
Ki = 630.96 nM
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CP0373152
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(+)-1-{(1S,2R,5R)-8-[2-(3,4-Dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonan-8-yl}propan-1-one
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C22H29Cl2N3O2
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1
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| 1 |
Ki = 650 nM
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CP0488298
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2-(3,4-dichlorophenyl)-1-[4-[(4-methoxyphenyl)methyl]-8-pyrrolidin-1-yl-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]ethanone
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C28H35Cl2N3O2
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1
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| 1 |
Ki = 740 nM
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CP0910342
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cis-4-(benzyloxy)-N,N-dimethyl-1-phenylcyclohexanamine hydrochloride
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C21H28ClNO
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1
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| 1 |
Ki = 830 nM
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CP0417987
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(-)-1-[(1R,2R,5S)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonan-8-yl]-2-(3,4-dichlorophenyl)ethanone
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C26H31Cl2N3O
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1
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| 1 |
Ki = 1150 nM
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CP0411823
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1-(4-benzoyl-8-pyrrolidin-1-yl-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl)-2-(3,4-dichlorophenyl)ethanone
Show/Hide
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C27H31Cl2N3O2
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1
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| 1 |
Ki = 1300 nM
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CP0471064
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1-[8-benzyl-8-(dimethylamino)-2-azaspiro[4.5]decan-2-yl]ethanone
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C20H30N2O
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1
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| 1 |
Ki = 1590 nM
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CP0112287
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(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-acetic acid
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C28H37N3O5
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1
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| 1 |
Ki = 1701 nM
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CP0480593
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ethyl 4-[2-(3,4-dichlorophenyl)acetyl]-5-pyrrolidin-1-yl-2,3,4a,5,6,7,8,8a-octahydroquinoxaline-1-carboxylate
Show/Hide
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C23H31Cl2N3O3
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1
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| 1 |
Ki = 1775 nM
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CP0489531
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2-(3-(1-cycloheptylpiperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide
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C22H32N4O2
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1
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| 1 |
Ki = 1794 nM
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CP0506550
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2-(3-(1-(cyclohexylmethyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide
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C22H32N4O2
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1
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| 1 |
Ki = 1883 nM
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CP0379863
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methyl 3-[4-[2-(3,4-dichlorophenyl)acetyl]-5-pyrrolidin-1-yl-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-3-oxopropanoate
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C24H31Cl2N3O4
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1
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| 1 |
Ki = 2200 nM
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CP0411821
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2-(3,4-dichlorophenyl)-1-[4-(pyridin-2-ylmethyl)-8-pyrrolidin-1-yl-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]ethanone
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C26H32Cl2N4O
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1
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| 1 |
Ki = 2260 nM
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CP0411820
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1-(4-butyl-8-pyrrolidin-1-yl-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl)-2-(3,4-dichlorophenyl)ethanone
Show/Hide
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C24H35Cl2N3O
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1
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| 1 |
Ki = 2300 nM
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CP0380373
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(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexanol
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C16H25NO2
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1
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| 1 |
Ki = 2400 nM
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CP0850829
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2-(3,4-Dichlorophenyl)-1-{(4aRS,8SR,8aRS)-4-[(pyridin-3-yl)-methyl]-8-(pyrrolidin-1-yl)perhydrochinoxalin-1-yl}ethan-1-one
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C26H32Cl2N4O
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1
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| 1 |
Ki = 2460 nM
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CP0500257
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2-(3-(1-(3,3-dimethylbutyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide
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C21H32N4O2
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1
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| 1 |
Ki = 2707 nM
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CP0411818
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2-(3,4-dichlorophenyl)-1-(8-pyrrolidin-1-yl-3,4,4a,5,6,7,8,8a-octahydro-2H-quinoxalin-1-yl)ethanone
Show/Hide
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C20H27Cl2N3O
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1
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| 1 |
Ki = 2800 nM
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CP0413580
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1-(4-acetyl-8-pyrrolidin-1-yl-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl)-2-(3,4-dichlorophenyl)ethanone
Show/Hide
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C22H29Cl2N3O2
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1
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| 1 |
Ki = 2800 nM
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CP0422119
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2-[3-(1-Cycloheptyl-piperidin-4-yl)-2,2-dioxo-2,3-dihydro-2lambda*6*-benzo[1,2,5]thiadiazol-1-yl]-N-methyl-acetamide
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C21H32N4O3S
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1
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| 1 |
Ki = 3177 nM
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CP0463554
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1-[4-[2-(3,4-dichlorophenyl)acetyl]-5-pyrrolidin-1-yl-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]propan-1-one
Show/Hide
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C23H31Cl2N3O2
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1
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| 1 |
Ki = 3335 nM
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CP0860430
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2-(3,4-Dichlorophenyl)-1-{(4aRS,8SR,8aSR)-4-[(pyridin-3-yl)-methyl]-8-[(3SR)-3-hydroxypyrrolidin-1-yl]-perhydrochinoxalin-1-yl}ethan-1-one
Show/Hide
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C26H32Cl2N4O2
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1
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| 1 |
Ki = 3480 nM
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CP0413579
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1-[4-benzoyl-8-(3-hydroxypyrrolidin-1-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-2-(3,4-dichlorophenyl)ethanone
Show/Hide
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C27H31Cl2N3O3
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1
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| 1 |
Ki = 3620 nM
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CP0474038
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1-[4-benzyl-8-(3-hydroxypyrrolidin-1-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-2-(3,4-dichlorophenyl)ethanone
Show/Hide
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C27H33Cl2N3O2
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1
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| 1 |
Ki = 4300 nM
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CP0864971
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2-(3,4-Dichlorophenyl)-1-{(4aRS,8SR,8aSR)-4-[(1H-imidazol-5-yl)methyl]-8-[(3SR)-3-hydroxypyrrolidin-1-yl]perhydroquinoxalin-1-yl}ethan-1-one
Show/Hide
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C24H31Cl2N5O2
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1
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| 1 |
Ki = 4400 nM
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CP0411824
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methyl 4-[2-(3,4-dichlorophenyl)acetyl]-5-(3-hydroxypyrrolidin-1-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxaline-1-carboxylate
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C22H29Cl2N3O4
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1
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| 1 |
Ki = 4450 nM
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CP0897021
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2-(3,4-Dichlorophenyl)-1-{(4aRS,8SR,8aRS)-4-[(1H-imidazol-5-yl)methyl]-8-(pyrrolidin-1-yl)perhydroquinoxalin-1-yl}ethan-1-one
Show/Hide
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C24H31Cl2N5O
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1
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| 1 |
Ki = 4690 nM
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CP0513068
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2-(3,4-dichlorophenyl)-1-[8-(3-hydroxypyrrolidin-1-yl)-3,4,4a,5,6,7,8,8a-octahydro-2H-quinoxalin-1-yl]ethanone
Show/Hide
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C20H27Cl2N3O2
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1
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| 1 |
Ki = 4900 nM
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CP0411819
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2-(3,4-dichlorophenyl)-1-(4-methyl-8-pyrrolidin-1-yl-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl)ethanone
Show/Hide
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C21H29Cl2N3O
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1
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| 1 |
Ki = 5100 nM
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CP0409534
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N,N-diethyl-4-[[(1S,4S,5S)-4-phenyl-8-propyl-6,8-diazabicyclo[3.2.2]nonan-6-yl]methyl]benzamide
Show/Hide
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C28H39N3O
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1
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| 1 |
Ki = 5700 nM
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CP0411822
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methyl 3-[4-[2-(3,4-dichlorophenyl)acetyl]-5-(3-hydroxypyrrolidin-1-yl)-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]-3-oxopropanoate
Show/Hide
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C24H31Cl2N3O5
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1
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| 1 |
Ki = 6000 nM
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CP0508087
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2-(3,4-dichlorophenyl)-1-[8-(3-hydroxypyrrolidin-1-yl)-4-methyl-2,3,4a,5,6,7,8,8a-octahydroquinoxalin-1-yl]ethanone
Show/Hide
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C21H29Cl2N3O2
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1
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| 1 |
Ki = 6000 nM
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CP0479308
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(1S,2S,5R)-methyl 8-(2-(3,4-dichlorophenyl)acetyl)-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonane-6-carboxylate
Show/Hide
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C21H27Cl2N3O3
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1
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| 1 |
Ki = 6120 nM
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CP0394322
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N,N-diethyl-4-[[(1S,4R,5S)-4-phenyl-8-prop-2-enyl-6,8-diazabicyclo[3.2.2]nonan-6-yl]methyl]benzamide
Show/Hide
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C28H37N3O
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1
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| 1 |
Ki = 6320 nM
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CP0433730
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N,N-diethyl-4-[[(1S,5S)-4-phenyl-8-prop-2-enyl-6,8-diazabicyclo[3.2.2]non-3-en-6-yl]methyl]benzamide
Show/Hide
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C28H35N3O
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1
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| 1 |
Ki = 6800 nM
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CP0394295
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N,N-diethyl-4-[[(1S,4S,5S)-4-phenyl-8-prop-2-enyl-6,8-diazabicyclo[3.2.2]nonan-6-yl]methyl]benzamide
Show/Hide
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C28H37N3O
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1
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| 1 |
Ki = 7300 nM
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CP0942370
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3-endo-(8-{2-[cyclohexylmethyl-((S)-2,3-dihydroxypropionyl)amino]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-benzoic acid
Show/Hide
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C26H38N2O5
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1
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| 1 |
Ki > 10 nM
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CP0376883
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methyl 1-[4-[2-(4-methylpiperazin-1-yl)benzimidazol-1-yl]piperidin-1-yl]cyclooctane-1-carboxylate
Show/Hide
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C27H41N5O2
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1
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| 1 |
Ki > 450 nM
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CP0376886
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(1-{4-[2-(3-Chloro-4-fluorophenyl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclohexyl)methanol
Show/Hide
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C25H29ClFN3O
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1
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| 1 |
Ki > 450 nM
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CP0377807
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(1-{4-[2-(3,3-Dimethylpiperazin-1-yl)-1H-benzimidazol-1-yl]piperidin-1-yl}cyclooctyl)methanol
Show/Hide
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C27H43N5O
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1
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| 1 |
Ki > 450 nM
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CP0393713
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1-{4-[2-(4-Methylpiperazin-1-yl)-1H-benzimidazol-1-yl]-piperidin-1-yl}cyclooctanecarboxylic acid
Show/Hide
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C26H39N5O2
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1
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| 1 |
Ki > 450 nM
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CP0441034
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N,N-dimethyl-1-[3-[4-(1-phenylethyl)piperazin-1-yl]propanoyl]-2,3-dihydroindole-2-carboxamide
Show/Hide
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C26H34N4O2
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1
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| 1 |
Ki > 450 nM
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CP0441035
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1-[3-(4-cyclohexylpiperazin-1-yl)propanoyl]-N,N-dimethyl-2,3-dihydroindole-2-carboxamide
Show/Hide
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C24H36N4O2
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1
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| 1 |
Ki > 450 nM
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CP0441045
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N,N-dimethyl-1-[3-(4-pentan-2-ylpiperazin-1-yl)propanoyl]-2,3-dihydroindole-2-carboxamide
Show/Hide
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C23H36N4O2
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1
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| 1 |
Ki > 450 nM
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CP0443595
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N,N-dimethyl-1-[3-(4-piperidin-1-ylpiperidin-1-yl)propanoyl]-2,3-dihydroindole-2-carboxamide
Show/Hide
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C24H36N4O2
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1
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| 1 |
Ki > 450 nM
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CP0458245
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1-[3-(4-benzylpiperazin-1-yl)propanoyl]-N,N-dimethyl-2,3-dihydroindole-2-carboxamide
Show/Hide
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C25H32N4O2
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1
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| 1 |
Ki > 450 nM
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CP0489871
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N,N-dimethyl-1-[3-(4-pentan-3-ylpiperazin-1-yl)propanoyl]-2,3-dihydroindole-2-carboxamide
Show/Hide
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C23H36N4O2
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1
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| 1 |
Ki > 450 nM
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CP0385701
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5-chloro-3-[[4-(4-fluoro-2-methylphenyl)piperidin-1-yl]methyl]-1,2,3,4-tetrahydroisoquinolin-8-ol
Show/Hide
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C22H26ClFN2O
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1
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| 1 |
Ki > 450 nM
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CP0386094
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spiro[1,2-dihydroindene-3,4'-piperidine]-1'-yl(1,2,3,4-tetrahydroisoquinolin-3-yl)methanone
Show/Hide
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C23H26N2O
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1
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| 1 |
Ki > 450 nM
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CP0038350
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(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-6-amino-2-[(2S)-2-[(2S)-2-{2-[(2S,3R)-2-[(2S)-2-(2-{2-[(2S)-2-amino-3-phenylpropanamido]acetamido}acetamido)-3-phenylpropanamido]-3-hydroxybutanamido]acetamido}propanamido]-5-carbamimidamidopentanamido]hexanamido]-3-hydroxypropanamido]propanamido]-5-carbamimidamidopentanamido]hexanamido]-4-methylpentanamido]propanamido]butanediamido]-4-carbamoylbutanoic acid
Show/Hide
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C79H129N27O22
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1
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| 1 |
Ki > 1000 nM
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CP0435078
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2-(3,4-dimethoxyphenyl)-N-methyl-N-[(1S)-1-phenyl-2-pyrrolidin-1-ylethyl]acetamide
Show/Hide
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C23H30N2O3
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1
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| 1 |
Ki > 1000 nM
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CP0372529
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(+)-1-{(1S,2S,5R)-8-[2-(3,4-Dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonan-8-yl}propan-1-one
Show/Hide
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C22H29Cl2N3O2
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1
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| 1 |
Ki > 1000 nM
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CP0390914
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(1R,2R,5S)-methyl 8-(2-(3,4-dichlorophenyl)acetyl)-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonane-6-carboxylate
Show/Hide
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C21H27Cl2N3O3
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1
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| 1 |
Ki > 1000 nM
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CP0390917
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(-)-1-{(1R,2R,5S)-8-[2-(3,4-Dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonan-8-yl}propan-1-one
Show/Hide
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C22H29Cl2N3O2
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1
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| 1 |
Ki > 1000 nM
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CP0390920
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(-)-1-{(1R,2S,5S)-8-[2-(3,4-Dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonan-8-yl}propan-1-one
Show/Hide
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C22H29Cl2N3O2
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1
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| 1 |
Ki > 1000 nM
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CP0390922
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(-)-Methyl(1R,2S,5S)-8-[2-(3,4-Dichlorophenyl)acetyl]-2-(pyrrolidin-1-yl)-6,8-diazabicyclo[3.2.2]nonane-6-carboxylate
Show/Hide
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C21H27Cl2N3O3
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1
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| 1 |
Ki > 1000 nM
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CP0475786
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(-)-1-[(1R,2S,5S)-6-Benzyl-2-(pyrrolidin-1-yl)-6,8-diazabicyclo-[3.2.2]nonan-8-yl]-2-(3,4-dichlorophenyl)ethanone
Show/Hide
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C26H31Cl2N3O
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1
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| 1 |
Ki > 1000 nM
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