General Information of the Compound
Compound ID
CP0512066
Compound Name
US9120797, 52
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Structure
Formula
C24H26FNOS2
Molecular Weight
427.61
Canonical SMILES
CN(C)C1(CCC2(CC1)c1sc3ccccc3c1CCS2=O)c1ccc(F)cc1
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InChI
InChI=1S/C24H26FNOS2/c1-26(2)23(17-7-9-18(25)10-8-17)12-14-24(15-13-23)22-20(11-16-29(24)27)19-5-3-4-6-21(19)28-22/h3-10H,11-16H2,1-2H3
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InChIKey
FTMRGQOSQDXGTG-UHFFFAOYSA-N
Physicochemical Property
logP
5.5716
Rotatable Bonds
2
Heavy Atom Count
29
Polar Areas
20.31
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 57720738
ChEMBL ID
CHEMBL3936891
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 58 nM
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