General Information of the Compound
Compound ID
CP0421844
Compound Name
N-butyl-2-[3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetamide
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Structure
Formula
C32H46N4O4
Molecular Weight
550.744
Canonical SMILES
CCCCNC(=O)Cn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O
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InChI
InChI=1S/C32H46N4O4/c1-6-7-17-33-31(37)22-35-27-10-8-9-11-28(27)36(32(35)38)25-14-18-34(19-15-25)20-16-29(23(2)3)40-30-21-26(39-5)13-12-24(30)4/h8-13,21,23,25,29H,6-7,14-20,22H2,1-5H3,(H,33,37)
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InChIKey
RHXCECMKFJHNGV-UHFFFAOYSA-N
Physicochemical Property
logP
5.16692
Rotatable Bonds
13
Heavy Atom Count
40
Polar Areas
77.73
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44437641
ChEMBL ID
CHEMBL240298
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 161 nM
   TI
   LI
   LO
   TS
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 29 nM
   TI
   LI
   LO
   TS