General Information of the Compound
Compound ID
CP0421885
Compound Name
methyl 1-phenacyl-4-(N-propanoylanilino)piperidine-4-carboxylate
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Structure
Formula
C24H28N2O4
Molecular Weight
408.498
Canonical SMILES
CCC(=O)N(c1ccccc1)C1(CCN(CC(=O)c2ccccc2)CC1)C(=O)OC
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InChI
InChI=1S/C24H28N2O4/c1-3-22(28)26(20-12-8-5-9-13-20)24(23(29)30-2)14-16-25(17-15-24)18-21(27)19-10-6-4-7-11-19/h4-13H,3,14-18H2,1-2H3
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InChIKey
BHIYWXAOQDVJSZ-UHFFFAOYSA-N
Physicochemical Property
logP
3.3201
Rotatable Bonds
7
Heavy Atom Count
30
Polar Areas
66.92
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 155548948
ChEMBL ID
CHEMBL4548662
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 0.2 nM
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