General Information of the Compound
Compound ID
CP0496455
Compound Name
ethyl 3-[4-[4-[[propanoyl-[6-(trifluoromethyl)pyridin-2-yl]amino]methyl]oxan-4-yl]piperazin-1-yl]propanoate
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Structure
Formula
C24H35F3N4O4
Molecular Weight
500.562
Canonical SMILES
CCOC(=O)CCN1CCN(CC1)C1(CN(C(=O)CC)c2cccc(n2)C(F)(F)F)CCOCC1
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InChI
InChI=1S/C24H35F3N4O4/c1-3-21(32)31(20-7-5-6-19(28-20)24(25,26)27)18-23(9-16-34-17-10-23)30-14-12-29(13-15-30)11-8-22(33)35-4-2/h5-7H,3-4,8-18H2,1-2H3
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InChIKey
WVZYAHUNVJPRKP-UHFFFAOYSA-N
Physicochemical Property
logP
2.9634
Rotatable Bonds
9
Heavy Atom Count
35
Polar Areas
75.21
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
7
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 137371217
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 598 nM
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