General Information of the Compound
Compound ID
CP0416873
Compound Name
4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(2-ethylphenyl)-1,3-thiazol-2-amine
    Show/Hide
Structure
Formula
C16H17N3S2
Molecular Weight
315.467
Canonical SMILES
CCc1ccccc1Nc1nc(cs1)-c1sc(C)nc1C
    Show/Hide
InChI
InChI=1S/C16H17N3S2/c1-4-12-7-5-6-8-13(12)18-16-19-14(9-20-16)15-10(2)17-11(3)21-15/h5-9H,4H2,1-3H3,(H,18,19)
    Show/Hide
InChIKey
JQYOLKVNJXHLBX-UHFFFAOYSA-N
Physicochemical Property
logP
5.18944
Rotatable Bonds
4
Heavy Atom Count
21
Polar Areas
37.81
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
21

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 746650
ChEMBL ID
CHEMBL4457219
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 4000 nM
   TI
   LI
   LO
   TS