General Information of the Compound
Compound ID
CP0568690
Compound Name
N-[[1-(4-benzylpiperazin-1-yl)cyclopropyl]methyl]-N-pyridin-2-ylpropanamide
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Structure
Formula
C23H30N4O
Molecular Weight
378.52
Canonical SMILES
CCC(=O)N(CC1(CC1)N1CCN(Cc2ccccc2)CC1)c1ccccn1
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InChI
InChI=1S/C23H30N4O/c1-2-22(28)27(21-10-6-7-13-24-21)19-23(11-12-23)26-16-14-25(15-17-26)18-20-8-4-3-5-9-20/h3-10,13H,2,11-12,14-19H2,1H3
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InChIKey
JXIUOVYAORJYHE-UHFFFAOYSA-N
Physicochemical Property
logP
3.175
Rotatable Bonds
7
Heavy Atom Count
28
Polar Areas
39.68
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 126539469
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 39 nM
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