General Information of the Compound
Compound ID
CP0917578
Compound Name
US9120797, 36
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Structure
Formula
C26H32N2O
Molecular Weight
388.555
Canonical SMILES
Cc1ccc2[nH]c3c(c2c1)CC(C)OC31CCC(c2ccccc2)(N(C)C)CC1
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InChI
InChI=1S/C26H32N2O/c1-18-10-11-23-21(16-18)22-17-19(2)29-26(24(22)27-23)14-12-25(13-15-26,28(3)4)20-8-6-5-7-9-20/h5-11,16,19,27H,12-15,17H2,1-4H3
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InChIKey
FJCNUXXAHZVGIR-UHFFFAOYSA-N
Physicochemical Property
logP
5.66392
Rotatable Bonds
2
Heavy Atom Count
29
Polar Areas
28.26
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11956286
SID: 17400256
ChEMBL ID
CHEMBL3892273
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 14 nM
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