General Information of the Compound
Compound ID
CP0500257
Compound Name
2-(3-(1-(3,3-dimethylbutyl)piperidin-4-yl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-methylacetamide
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Structure
Formula
C21H32N4O2
Molecular Weight
372.513
Canonical SMILES
CNC(=O)Cn1c2ccccc2n(C2CCN(CCC(C)(C)C)CC2)c1=O
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InChI
InChI=1S/C21H32N4O2/c1-21(2,3)11-14-23-12-9-16(10-13-23)25-18-8-6-5-7-17(18)24(20(25)27)15-19(26)22-4/h5-8,16H,9-15H2,1-4H3,(H,22,26)
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InChIKey
DOGYUXXGMZAOPV-UHFFFAOYSA-N
Physicochemical Property
logP
2.6221
Rotatable Bonds
5
Heavy Atom Count
27
Polar Areas
59.27
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 46880155
ChEMBL ID
CHEMBL1088569
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 2707 nM
   TI
   LI
   LO
   TS
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 186 nM
   TI
   LI
   LO
   TS