General Information of the Compound
Compound ID
CP0553467
Compound Name
1-(2,4-dichlorophenyl)-6,6-dimethyl-3-(trifluoromethyl)-5,7-dihydroindazol-4-one
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Structure
Formula
C16H13Cl2F3N2O
Molecular Weight
377.193
Canonical SMILES
CC1(C)Cc2c(c(nn2-c2ccc(Cl)cc2Cl)C(F)(F)F)C(=O)C1
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InChI
InChI=1S/C16H13Cl2F3N2O/c1-15(2)6-11-13(12(24)7-15)14(16(19,20)21)22-23(11)10-4-3-8(17)5-9(10)18/h3-5H,6-7H2,1-2H3
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InChIKey
LCJMHYUOSFBKDY-UHFFFAOYSA-N
Physicochemical Property
logP
5.353
Rotatable Bonds
1
Heavy Atom Count
24
Polar Areas
34.89
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 118711137
ChEMBL ID
CHEMBL3325718
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 1540 nM
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