General Information of the Compound
Compound ID
CP0399720
Compound Name
N-tert-butyl-2-[3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetamide
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Structure
Formula
C32H46N4O4
Molecular Weight
550.744
Canonical SMILES
COc1ccc(C)c(OC(CCN2CCC(CC2)n2c3ccccc3n(CC(=O)NC(C)(C)C)c2=O)C(C)C)c1
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InChI
InChI=1S/C32H46N4O4/c1-22(2)28(40-29-20-25(39-7)13-12-23(29)3)16-19-34-17-14-24(15-18-34)36-27-11-9-8-10-26(27)35(31(36)38)21-30(37)33-32(4,5)6/h8-13,20,22,24,28H,14-19,21H2,1-7H3,(H,33,37)
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InChIKey
HYIZZMKORUTBGZ-UHFFFAOYSA-N
Physicochemical Property
logP
5.16532
Rotatable Bonds
10
Heavy Atom Count
40
Polar Areas
77.73
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44437643
ChEMBL ID
CHEMBL399393
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 245 nM
   TI
   LI
   LO
   TS
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 155 nM
   TI
   LI
   LO
   TS