General Information of the Compound
Compound ID
CP0426963
Compound Name
N-(2-methoxyethyl)-2-[3-[1-[3-(5-methoxy-2-methylphenoxy)-4-methylpentyl]piperidin-4-yl]-2-oxobenzimidazol-1-yl]acetamide
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Structure
Formula
C31H44N4O5
Molecular Weight
552.716
Canonical SMILES
COCCNC(=O)Cn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O
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InChI
InChI=1S/C31H44N4O5/c1-22(2)28(40-29-20-25(39-5)11-10-23(29)3)14-18-33-16-12-24(13-17-33)35-27-9-7-6-8-26(27)34(31(35)37)21-30(36)32-15-19-38-4/h6-11,20,22,24,28H,12-19,21H2,1-5H3,(H,32,36)
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InChIKey
PLAUREMHVUKPSU-UHFFFAOYSA-N
Physicochemical Property
logP
4.01322
Rotatable Bonds
13
Heavy Atom Count
40
Polar Areas
86.96
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
8
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44437645
ChEMBL ID
CHEMBL241157
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 180 nM
   TI
   LI
   LO
   TS
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 436 nM
   TI
   LI
   LO
   TS
2
Ki = 20 nM
   TI
   LI
   LO
   TS