General Information of the Compound
Compound ID
CP0416874
Compound Name
4-(2,4-dimethyl-1,3-oxazol-5-yl)-N-(2,4,6-trimethylphenyl)-1,3-thiazol-2-amine
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Structure
Formula
C17H19N3OS
Molecular Weight
313.426
Canonical SMILES
Cc1nc(C)c(o1)-c1csc(Nc2c(C)cc(C)cc2C)n1
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InChI
InChI=1S/C17H19N3OS/c1-9-6-10(2)15(11(3)7-9)20-17-19-14(8-22-17)16-12(4)18-13(5)21-16/h6-8H,1-5H3,(H,19,20)
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InChIKey
ZFFNCDOHICCJFJ-UHFFFAOYSA-N
Physicochemical Property
logP
5.0838
Rotatable Bonds
3
Heavy Atom Count
22
Polar Areas
50.95
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
22

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 126619428
ChEMBL ID
CHEMBL4541902
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 3900 nM
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