Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-methyl-9-(2-pyridin-2-ylethyl)-4-[4-(trifluoromethyl)pyridin-3-yl]-1-oxa-4,9-diazaspiro[5.5]undecan-3-one
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 PubChem ID
CID: 118567689
Canonical SMILES
CC1OC2(CCN(CCc3ccccn3)CC2)CN(C1=O)c1cnccc1C(F)(F)F
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Compound Formula C22H25F3N4O2
Compound Structure
Protein Name
 Protein Info 
Mu-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Opioid receptor
Uniprot ID
P35372
Gene Name
OPRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 767 nM
   TI
   LI
   LO
   TS
2
Ki = 127 nM
   TI
   LI
   LO
   TS