Brief Information of the Compound and Protein
Compound Name
Trans-2',3',4',9'-Tetrahydro-N,N-dimethyl-4-phenyl-spiro[cyclohexane-1,1'-pyrido[3,4-b]indol]-4-amine Dihydrochloride
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Canonical SMILES
CN(C)[C@]1(c2ccccc2)CC[C@]2(CC1)NCCc1c3ccccc3[nH]c12.Cl
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Compound Formula C24H30ClN3
Compound Structure
Protein Name
Mu-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Opioid receptor
Uniprot ID
P35372
Gene Name
OPRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
EC50 = 0.2 nM
   TI
   LI
   LO
   TS
2
Ki = 0.39 nM
   TI
   LI
   LO
   TS