General Information of the Compound
Compound ID
CP0273301
Compound Name
N-[(3-fluorophenyl)methyl]-N-[1-(2-phenylethyl)piperidin-4-yl]furan-2-carboxamide
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Structure
Formula
C25H27FN2O2
Molecular Weight
406.501
Canonical SMILES
Fc1cccc(CN(C2CCN(CCc3ccccc3)CC2)C(=O)c2ccco2)c1
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InChI
InChI=1S/C25H27FN2O2/c26-22-9-4-8-21(18-22)19-28(25(29)24-10-5-17-30-24)23-12-15-27(16-13-23)14-11-20-6-2-1-3-7-20/h1-10,17-18,23H,11-16,19H2
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InChIKey
KFNBRURSYGJOHJ-UHFFFAOYSA-N
Physicochemical Property
logP
4.7682
Rotatable Bonds
7
Heavy Atom Count
30
Polar Areas
36.69
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 164851904
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 48.5 nM
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