General Information of the Compound
Compound ID
CP0509129
Compound Name
methyl 4-(3,6,6-trimethyl-4-oxo-5,7-dihydroindazol-1-yl)benzoate
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Structure
Formula
C18H20N2O3
Molecular Weight
312.369
Canonical SMILES
COC(=O)c1ccc(cc1)-n1nc(C)c2c1CC(C)(C)CC2=O
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InChI
InChI=1S/C18H20N2O3/c1-11-16-14(9-18(2,3)10-15(16)21)20(19-11)13-7-5-12(6-8-13)17(22)23-4/h5-8H,9-10H2,1-4H3
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InChIKey
YECFXTYKISJUAQ-UHFFFAOYSA-N
Physicochemical Property
logP
3.12242
Rotatable Bonds
2
Heavy Atom Count
23
Polar Areas
61.19
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
23

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 4247619
ChEMBL ID
CHEMBL3325706
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 10000 nM
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