Brief Information of the Compound and Protein
Compound Name
methyl 2-[3-oxo-4-phenyl-9-(2-phenylethyl)-1-oxa-4,9-diazaspiro[5.5]undecan-2-yl]acetate
    Show/Hide
PubChem ID
CID: 118562469
Canonical SMILES
COC(=O)CC1OC2(CCN(CCc3ccccc3)CC2)CN(C1=O)c1ccccc1
    Show/Hide
Compound Formula C25H30N2O4
Compound Structure
Protein Name
Mu-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Opioid receptor
Uniprot ID
P35372
Gene Name
OPRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  2
1
EC50 = 181 nM
   TI
   LI
   LO
   TS
2
Ki = 92 nM
   TI
   LI
   LO
   TS