General Information of the Compound
Compound ID
CP0505592
Compound Name
2-(3-{1-[3-(5-methoxy-2-methyl-phenoxy)-4-methylpentyl]-piperidin-4-yl}-2-oxo-2,3-dihydro-benzimidazol-1-yl)-N-propyl-acetamide
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Structure
Formula
C31H44N4O4
Molecular Weight
536.717
Canonical SMILES
CCCNC(=O)Cn1c2ccccc2n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c1=O
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InChI
InChI=1S/C31H44N4O4/c1-6-16-32-30(36)21-34-26-9-7-8-10-27(26)35(31(34)37)24-13-17-33(18-14-24)19-15-28(22(2)3)39-29-20-25(38-5)12-11-23(29)4/h7-12,20,22,24,28H,6,13-19,21H2,1-5H3,(H,32,36)
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InChIKey
UMNWAEGGFCQDQV-UHFFFAOYSA-N
Physicochemical Property
logP
4.77682
Rotatable Bonds
12
Heavy Atom Count
39
Polar Areas
77.73
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
39

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44437640
ChEMBL ID
CHEMBL240086
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
Ki = 272 nM
   TI
   LI
   LO
   TS
Protein ID: PT01360, Nociceptin receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 1219 nM
   TI
   LI
   LO
   TS
2
Ki = 19 nM
   TI
   LI
   LO
   TS