General Information of the Compound
Compound ID
CP0572662
Compound Name
N-[2-(4-benzylpiperazin-1-yl)-2-methylpropyl]-N-phenylpropanamide
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Structure
Formula
C24H33N3O
Molecular Weight
379.548
Canonical SMILES
CCC(=O)N(CC(C)(C)N1CCN(Cc2ccccc2)CC1)c1ccccc1
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InChI
InChI=1S/C24H33N3O/c1-4-23(28)27(22-13-9-6-10-14-22)20-24(2,3)26-17-15-25(16-18-26)19-21-11-7-5-8-12-21/h5-14H,4,15-20H2,1-3H3
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InChIKey
AORIOLLAPPJVNF-UHFFFAOYSA-N
Physicochemical Property
logP
4.026
Rotatable Bonds
7
Heavy Atom Count
28
Polar Areas
26.79
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 126539563
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 299 nM
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