General Information of the Compound
Compound ID
CP0574198
Compound Name
N-[[1-(4-benzylpiperazin-1-yl)cyclohexyl]methyl]-N-phenylpropanamide
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Structure
Formula
C27H37N3O
Molecular Weight
419.613
Canonical SMILES
CCC(=O)N(CC1(CCCCC1)N1CCN(Cc2ccccc2)CC1)c1ccccc1
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InChI
InChI=1S/C27H37N3O/c1-2-26(31)30(25-14-8-4-9-15-25)23-27(16-10-5-11-17-27)29-20-18-28(19-21-29)22-24-12-6-3-7-13-24/h3-4,6-9,12-15H,2,5,10-11,16-23H2,1H3
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InChIKey
WFAJJUAIPMLRAE-UHFFFAOYSA-N
Physicochemical Property
logP
4.9503
Rotatable Bonds
7
Heavy Atom Count
31
Polar Areas
26.79
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 126539533
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 158 nM
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