General Information of the Compound
Compound ID
CP0496453
Compound Name
N-benzyl-N-[[1-(4-benzylpiperazin-1-yl)cyclopropyl]methyl]propanamide
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Structure
Formula
C25H33N3O
Molecular Weight
391.559
Canonical SMILES
CCC(=O)N(Cc1ccccc1)CC1(CC1)N1CCN(Cc2ccccc2)CC1
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InChI
InChI=1S/C25H33N3O/c1-2-24(29)27(20-23-11-7-4-8-12-23)21-25(13-14-25)28-17-15-26(16-18-28)19-22-9-5-3-6-10-22/h3-12H,2,13-21H2,1H3
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InChIKey
OZXQHIYNACJCJT-UHFFFAOYSA-N
Physicochemical Property
logP
3.7756
Rotatable Bonds
8
Heavy Atom Count
29
Polar Areas
26.79
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 137371461
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 > 10000 nM
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