General Information of the Compound
Compound ID
CP0273298
Compound Name
N-[(4-fluorophenyl)methyl]-N-[1-(2-phenylethyl)piperidin-4-yl]butanamide
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Structure
Formula
C24H31FN2O
Molecular Weight
382.523
Canonical SMILES
CCCC(=O)N(Cc1ccc(F)cc1)C1CCN(CCc2ccccc2)CC1
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InChI
InChI=1S/C24H31FN2O/c1-2-6-24(28)27(19-21-9-11-22(25)12-10-21)23-14-17-26(18-15-23)16-13-20-7-4-3-5-8-20/h3-5,7-12,23H,2,6,13-19H2,1H3
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InChIKey
AXXWJGVWCSPDTD-UHFFFAOYSA-N
Physicochemical Property
logP
4.6615
Rotatable Bonds
8
Heavy Atom Count
28
Polar Areas
23.55
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 164851917
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01515, Mu-type opioid receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 121.8 nM
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