Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-[2-(2-fluorophenyl)ethyl]-12-[2-(trifluoromethyl)pyridin-3-yl]-4-oxa-8,12-diazadispiro[2.1.55.33]tridecan-13-one
    Show/Hide
 PubChem ID
CID: 118567543
Canonical SMILES
Fc1ccccc1CCN1CCC2(CC1)CN(C(=O)C1(CC1)O2)c1cccnc1C(F)(F)F
    Show/Hide
Compound Formula C24H25F4N3O2
Compound Structure
Protein Name
 Protein Info 
Mu-type opioid receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Opioid receptor
Uniprot ID
P35372
Gene Name
OPRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 195 nM
   TI
   LI
   LO
   TS
2
Ki = 175 nM
   TI
   LI
   LO
   TS