| Compound ID |
Compound Name |
Compound Formula |
|
CP0502905
|
(R)-3-cyclopropyl-2-((3S,4S)-3-((4-(3,3-difluoro-3-(4-fluorophenyl)propyl)piperidin-1-yl)methyl)-4-(3-fluorophenyl)pyrrolidin-1-yl)propanoic acid
Show/Hide
|
C31H38F4N2O2
|
1
|
| 1 |
IC50 = 0.06 nM
|
|
|
|
CP0446562
|
Allyl-{1-[(S)-4-(benzenesulfonyl-methyl-amino)-3-methyl-3-phenyl-butyl]-piperidin-4-yl}-carbamic acid 4-nitro-benzyl ester
Show/Hide
|
C34H42N4O6S
|
2
|
| 1 |
IC50 = 0.1 nM
|
|
|
| 2 |
IC50 = 1 nM
|
|
|
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CP0463620
|
Allyl-[1-((3S,4S)-1-benzyl-4-phenyl-pyrrolidin-3-ylmethyl)-piperidin-4-yl]-carbamic acid 4-nitro-benzyl ester
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|
C34H40N4O4
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0221310
|
(R)-3-Cyclobutyl-2-{(3S,4S)-3-phenyl-4-[4-(3-phenyl-propyl)-piperidin-1-ylmethyl]-pyrrolidin-1-yl}-propionic acid
Show/Hide
|
C32H44N2O2
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0508636
|
(R)-3-Cyclobutyl-2-((S)-3-(3-fluoro-phenyl)-4-{4-[2-(4-fluoro-phenylsulfanyl)-ethyl]-piperidin-1-ylmethyl}-pyrrolidin-1-yl)-propionic acid
Show/Hide
|
C31H40F2N2O2S
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0150112
|
(R)-3-cyclopropyl-2-((3S,4S)-3-phenyl-4-((4-(3-phenylpropyl)piperidin-1-yl)methyl)pyrrolidin-1-yl)propanoic acid
Show/Hide
|
C31H42N2O2
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0320384
|
(R)-2-cyclobutyl-2-((3S,4S)-3-phenyl-4-((4-(3-phenylpropyl)piperidin-1-yl)methyl)pyrrolidin-1-yl)acetic acid
Show/Hide
|
C31H42N2O2
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0399161
|
N-[1-[(3R)-3-(3,5-dichlorophenyl)-3-(1-methylsulfonylpiperidin-4-yl)propyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C31H43Cl2N3O5S2
|
1
|
| 1 |
IC50 < 0.1 nM
|
|
|
|
CP0438185
|
N-[1-[(3R)-3-(3,5-dimethylphenyl)-3-(1-methylsulfonylpiperidin-4-yl)propyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C33H49N3O5S2
|
1
|
| 1 |
IC50 < 0.1 nM
|
|
|
|
CP0459823
|
N-ethyl-2-(4-methylsulfonylphenyl)-N-[1-[(3R)-3-phenyl-3-[1-(trifluoromethylsulfonyl)piperidin-4-yl]propyl]piperidin-4-yl]acetamide
Show/Hide
|
C31H42F3N3O5S2
|
1
|
| 1 |
IC50 < 0.1 nM
|
|
|
|
CP0495736
|
4N-allyl-4N-[4-nitrobenzyloxycarboyl]-1-[4'-phenyl-(3a'S,4'S,5'S)-spiro[cyclohexane-1,2'-perhydropyrrolo[1,2-b]isoxazole]-5-ylmethyl]hexahydro-4-pyridinamine
Show/Hide
|
C34H44N4O5
|
1
|
| 1 |
IC50 = 0.13 nM
|
|
|
|
CP0460696
|
Allyl-[1-((3S,4S)-1-cyclopentanecarbonyl-4-phenyl-pyrrolidin-3-ylmethyl)-piperidin-4-yl]-carbamic acid 4-nitro-benzyl ester
Show/Hide
|
C33H42N4O5
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0468279
|
Allyl-[1-((3S,4S)-1-benzoyl-4-phenyl-pyrrolidin-3-ylmethyl)-piperidin-4-yl]-carbamic acid 4-nitro-benzyl ester
Show/Hide
|
C34H38N4O5
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0287577
|
1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmethyl)-4-{3-[4-(1H-tetrazol-5-yl)-phenyl]-propyl}-piperidin-4-ol
Show/Hide
|
C33H46N6O
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0538378
|
1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmethyl)-4-{3-[4-(1-methyl-1H-tetrazol-5-yl)-phenyl]-propyl}-piperidin-4-ol
Show/Hide
|
C34H48N6O
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0375003
|
(R)-3-cyclobutyl-2-((3S,4S)-3-((4-(3,3-difluoro-3-(4-fluorophenyl)propyl)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)propanoic acid
Show/Hide
|
C32H41F3N2O2
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0383720
|
(R)-3-Cyclobutyl-2-((S)-3-(3-fluoro-phenyl)-4-{4-[3-(4-trifluoromethyl-phenyl)-propyl]-piperidin-1-ylmethyl}-pyrrolidin-1-yl)-propionic acid
Show/Hide
|
C33H42F4N2O2
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0042381
|
(R)-2-cyclopentyl-2-((3S,4S)-3-phenyl-4-((4-(3-phenylpropyl)piperidin-1-yl)methyl)pyrrolidin-1-yl)acetic acid
Show/Hide
|
C32H44N2O2
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0476055
|
(R)-2-[(2S,3S)-3-[4-(2-Ethyl-5-naphthalen-1-ylmethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C38H47FN4O2
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0488131
|
(R)-2-[(2S,3S)-3-[4-(2-Ethyl-5-naphthalen-2-ylmethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C38H47FN4O2
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0495887
|
(R)-Cyclohexyl-[(2S,3S)-3-{4-[5-(4-cyclopropoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-acetic acid
Show/Hide
|
C39H51FN4O3
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0543841
|
(2R,4R)-2-[(2S,3S)-3-[4-(2-Ethyl-5-naphthalen-2-ylmethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C38H47FN4O2
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0543846
|
(2R,4R)-2-[(2S,3S)-3-[4-(2-Ethyl-5-naphthalen-1-ylmethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C38H47FN4O2
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0453265
|
(R)-N-ethyl-N-(1-(3-(3-fluorophenyl)-3-(4-(methylsulfonyl)phenyl)propyl)piperidin-4-yl)-2-(4-(methylsulfonyl)phenyl)acetamide
Show/Hide
|
C32H39FN2O5S2
|
1
|
| 1 |
IC50 = 0.22 nM
|
|
|
|
CP0126599
|
N-[1-[(3R)-3-(3,5-difluorophenyl)-3-(1-methylsulfonylpiperidin-4-yl)propyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C31H43F2N3O5S2
|
1
|
| 1 |
IC50 = 0.26 nM
|
|
|
|
CP0437586
|
1-((3S,4S)-1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmethyl)-4-(3-phenyl-propyl)-piperidin-4-ol
Show/Hide
|
C32H46N2O
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0454400
|
(R)-3-cyclobutyl-2-((3S,4S)-3-((4-(3,3-difluoro-3-(4-fluorophenyl)propyl)piperidin-1-yl)methyl)-4-(3-fluorophenyl)pyrrolidin-1-yl)propanoic acid
Show/Hide
|
C32H40F4N2O2
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0508634
|
(R)-Cyclohexyl-((3S,4S)-3-{4-[3,3-difluoro-3-(4-fluoro-phenyl)-propyl]-piperidin-1-ylmethyl}-4-phenyl-pyrrolidin-1-yl)-acetic acid
Show/Hide
|
C33H43F3N2O2
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0536757
|
(R)-2-[(S)-3-{4-[3-(4-Cyano-phenyl)-propyl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-cyclobutyl-propionic acid
Show/Hide
|
C33H42FN3O2
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0409845
|
(R)-3-Cyclobutyl-2-[(3S,4S)-3-[4-(6-fluoro-imidazo[1,2-a]pyridin-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-propionic acid
Show/Hide
|
C30H36F2N4O2
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0046234
|
(2R,4S)-2-[(2S,3S)-3-[4-(5-Biphenyl-4-ylmethyl-2-ethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C40H49FN4O2
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0245753
|
(2R,4S)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-isopropyl-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C37H51FN4O2
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0268798
|
(R)-[(2S,3S)-3-[4-(5-Biphenyl-4-ylmethyl-2-ethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-cyclohexyl-acetic acid
Show/Hide
|
C42H51FN4O2
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0409952
|
(2R,4S)-2-[(2S,3S)-3-{4-[5-(4-tert-Butyl-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C38H53FN4O2
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0463742
|
(2R,4S)-2-[(2S,3S)-3-{4-[5-(4-Cyclopropoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C37H49FN4O3
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0487576
|
(2R,4S)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-methyl-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C35H47FN4O2
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0490201
|
(2R,4R)-2-[(2S,3S)-3-{4-[5-(4-Cyclopropoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C37H49FN4O3
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0502381
|
(2R,4S)-2-[(2S,3S)-3-{4-[5-(4-Difluoromethoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C35H45F3N4O3
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
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CP0502900
|
(2R,4S)-2-[(2S,3S)-3-[4-(2-Ethyl-5-naphthalen-2-ylmethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C38H47FN4O2
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0506452
|
(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-trifluoromethyl-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C35H44F4N4O2
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0512127
|
(R)-2-[(2S,3S)-3-[4-(5-Biphenyl-4-ylmethyl-2-ethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
|
C39H47FN4O2
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
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CP0467621
|
(4R)-3-[1-[1-(6-chloro-2,4-dimethylpyridine-3-carbonyl)-4-methylpiperidin-4-yl]piperidin-4-yl]-1-cyclohexyl-4-phenylimidazolidin-2-one
Show/Hide
|
C34H46ClN5O2
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0081972
|
(R)-N-(1-(3-(3,5-difluorophenyl)-3-(4-(methylsulfonyl)phenyl)propyl)piperidin-4-yl)-N-ethyl-2-(4-(methylsulfonyl)phenyl)acetamide
Show/Hide
|
C32H38F2N2O5S2
|
1
|
| 1 |
IC50 = 0.32 nM
|
|
|
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CP0523760
|
(R)-3-Cyclobutyl-2-[(3S,4S)-3-[4-(7-ethyl-imidazo[1,2-a]pyridin-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-propionic acid
Show/Hide
|
C32H41FN4O2
|
1
|
| 1 |
IC50 = 0.35 nM
|
|
|
|
CP0946162
|
5-(4-{3-[1-((3S,4S)-1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmethyl)-4-hydroxy-piperidin-4-yl]-propyl}-phenyl)-2-methyl-1H-tetrazol-2-ium
Show/Hide
|
C34H49N6O+
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0512053
|
(R)-3-Cyclobutyl-2-((3S,4S)-3-(3-fluoro-phenyl)-4-{4-[(5-fluoro-pyrimidin-2-yl)-propyl-amino]-piperidin-1-ylmethyl}-pyrrolidin-1-yl)-propionic acid
Show/Hide
|
C30H41F2N5O2
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0460286
|
(2R)-3-cyclopropyl-2-((3S,4S)-3-(3-fluorophenyl)-4-((4-(3-(4-fluorophenyl)-3-hydroxypropyl)piperidin-1-yl)methyl)pyrrolidin-1-yl)propanoic acid
Show/Hide
|
C31H40F2N2O3
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
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CP0091845
|
(2R,4R)-2-[(2S,3S)-3-{4-[5-(4-Cyclobutoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C38H51FN4O3
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0276980
|
(R)-2-[(2S,3S)-3-{4-[5-(4-tert-Butyl-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C38H53FN4O2
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
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CP0492765
|
(R)-2-[(2S,3S)-3-{4-[5-(4-Ethoxy-3-fluoro-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
|
C35H46F2N4O3
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
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CP0493513
|
(2R,4R)-2-[(2S,3S)-3-{4-[5-(4-Ethoxy-3-fluoro-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C36H48F2N4O3
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
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CP0497595
|
(2R,4S)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-phenoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C40H49FN4O3
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
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CP0535143
|
(R)-2-[(2S,3S)-3-{4-[5-(3-Ethoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C36H49FN4O3
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
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CP0535421
|
(2R,4S)-2-[(2S,3S)-3-[4-(2-Ethyl-5-naphthalen-1-ylmethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C38H47FN4O2
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
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CP0541947
|
2-[3-{4-[2-Ethyl-5-(4-phenoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C40H49FN4O3
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
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CP0543834
|
(R)-2-[(2S,3S)-3-{4-[5-(4-Cyclopropoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C37H49FN4O3
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
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CP0517314
|
4-[6-methyl-5-[[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]pyridin-2-yl]sulfanylbenzoic acid
Show/Hide
|
C33H38N4O4S
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
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CP0136617
|
(2R)-3-cyclobutyl-2-[(3S,4S)-3-(3-fluorophenyl)-4-[(4-imidazo[1,2-a]pyridin-3-ylpiperidin-1-yl)methyl]pyrrolidin-1-yl]propanoic acid
Show/Hide
|
C30H37FN4O2
|
1
|
| 1 |
IC50 = 0.42 nM
|
|
|
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CP0438156
|
N-ethyl-N-[1-[(3R)-3-(3-methylphenyl)-3-(1-methylsulfonylpiperidin-4-yl)propyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C32H47N3O5S2
|
1
|
| 1 |
IC50 = 0.44 nM
|
|
|
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CP0427326
|
(R)-3-Cyclobutyl-2-((3S,4S)-3-(3-fluoro-phenyl)-4-{4-[propyl-(5-trifluoromethyl-pyrimidin-2-yl)-amino]-piperidin-1-ylmethyl}-pyrrolidin-1-yl)-propionic acid
Show/Hide
|
C31H41F4N5O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
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CP0431694
|
(R)-3-Cyclobutyl-2-{(S)-3-(3-fluoro-phenyl)-4-[4-(3-phenyl-propyl)-piperidin-1-ylmethyl]-pyrrolidin-1-yl}-propionic acid
Show/Hide
|
C32H43FN2O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
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CP0539871
|
2-[(S)-3-{4-[3,3-Difluoro-3-(4-fluoro-phenyl)-propyl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-(R)-methyl-butyric acid
Show/Hide
|
C30H38F4N2O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0530332
|
(R)-2-((3S,4S)-3-((4-(3,3-difluoro-3-(4-fluorophenyl)propyl)piperidin-1-yl)methyl)-4-(3-fluorophenyl)pyrrolidin-1-yl)-4-methylpentanoic acid
Show/Hide
|
C31H40F4N2O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0525662
|
(2,6-dimethylphenyl)(4-methyl-4-(4-(phenyl(pyridin-3-yl)amino)piperidin-1-yl)piperidin-1-yl)methanone
Show/Hide
|
C31H38N4O
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0393264
|
(R)-3-Cyclobutyl-2-[(3S,4S)-3-[4-(6,8-dichloro-imidazo[1,2-a]pyridin-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-propionic acid
Show/Hide
|
C30H35Cl2FN4O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0380771
|
(2R,4R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-phenoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C40H49FN4O3
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0405996
|
(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(2-fluoro-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C34H44F2N4O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0406308
|
(2R,4S)-2-[(2S,3S)-3-{4-[5-(3-Cyano-4-methoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C36H46FN5O3
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0415122
|
(2R,4S)-2-[(2S,3S)-3-[4-(5-Benzo[1,3]dioxol-5-ylmethyl-2-ethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C35H45FN4O4
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0437648
|
(R)-2-[(2S,3S)-3-{4-[5-(4-Butoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
|
C37H51FN4O3
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0447717
|
(2R,4S)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-trifluoromethyl-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C35H44F4N4O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0448181
|
(2R,4R)-2-[(2S,3S)-3-{4-[5-(4-Benzyloxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C41H51FN4O3
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0448276
|
(R)-2-[(2S,3S)-3-{4-[5-(4-Difluoromethoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C35H45F3N4O3
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0492764
|
(R)-2-[(2S,3S)-3-{4-[5-(4-Difluoromethoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
|
C34H43F3N4O3
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0495926
|
(R)-Cyclohexyl-[(2S,3S)-3-{4-[2-ethyl-5-(4-hydroxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-acetic acid
Show/Hide
|
C36H47FN4O3
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0496243
|
(2R,4S)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(3-methylamino-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C35H48FN5O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0501581
|
(2R,4R)-2-[(2S,3S)-3-(4-{2-Ethyl-5-[4-(2,2,2-trifluoro-ethoxy)-benzyl]-2H-pyrazol-3-yl}-piperidin-1-ylmethyl)-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C36H46F4N4O3
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0501931
|
(2R,4R)-2-[(2S,3S)-3-[4-(5-Biphenyl-4-ylmethyl-2-ethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C40H49FN4O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0508120
|
(R)-[(2S,3S)-3-{4-[5-(4-tert-Butoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-cyclohexyl-acetic acid
Show/Hide
|
C40H55FN4O3
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0539901
|
(2R)-2-cyclohexyl-2-[(3S,4S)-3-[[4-[2-ethyl-5-[(4-phenoxyphenyl)methyl]pyrazol-3-yl]piperidin-1-yl]methyl]-4-(3-fluorophenyl)pyrrolidin-1-yl]acetic acid
Show/Hide
|
C42H51FN4O3
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0548989
|
(2R,4R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-trifluoromethyl-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C35H44F4N4O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0375373
|
6-chloro-N-[(3S)-3-[4-[(5R)-3-cyclohexyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
Show/Hide
|
C32H44ClN5O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0463000
|
N-[1-[(3R)-3-(3-chlorophenyl)-3-(1-methylsulfonylpiperidin-4-yl)propyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C31H44ClN3O5S2
|
1
|
| 1 |
IC50 = 0.55 nM
|
|
|
|
CP0440545
|
3-({[1'-(2,4-Dimethyl-1-oxy-pyridine-3-carbonyl)-4'-methyl-[1,4']bipiperidinyl-4-yl]-phenyl-amino}-methyl)-benzonitrile
Show/Hide
|
C33H39N5O2
|
2
|
| 1 |
IC50 = 0.6 nM
|
|
|
| 2 |
IC50 = 10.8 nM
|
|
|
|
CP0514270
|
(R)-3-Cyclobutyl-2-{(3S,4S)-3-(3-fluoro-phenyl)-4-[4-(6-nitro-imidazo[1,2-a]pyridin-3-yl)-piperidin-1-ylmethyl]-pyrrolidin-1-yl}-propionic acid
Show/Hide
|
C30H36FN5O4
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0046425
|
(R)-2-[(2S,3S)-3-[4-(5-Biphenyl-4-ylmethyl-2-ethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C40H49FN4O2
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0183022
|
2-[3-{4-[2-Ethyl-5-(4-trifluoromethoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C35H44F4N4O3
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0258489
|
(2R,4S)-2-[(2S,3S)-3-{4-[5-(4-Ethoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C36H49FN4O3
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0289486
|
(2R,4S)-2-[(2S,3S)-3-(4-{2-Ethyl-5-[4-(2,2,2-trifluoro-ethoxy)-benzyl]-2H-pyrazol-3-yl}-piperidin-1-ylmethyl)-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C36H46F4N4O3
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0373375
|
(2R,4S)-2-[(2S,3S)-3-{4-[5-(4-Benzenesulfonyl-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C40H49FN4O4S
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0399645
|
2-[3-{4-[2-Ethyl-5-(4-trifluoromethoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C35H44F4N4O3
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0404795
|
(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-hydroxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
|
C33H43FN4O3
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0405932
|
(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-isopropyl-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C37H51FN4O2
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0405949
|
(2R,4R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-hydroxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C34H45FN4O3
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0492844
|
(R)-2-[(2S,3S)-3-(4-{2-Ethyl-5-[4-(2,2,2-trifluoro-ethoxy)-benzyl]-2H-pyrazol-3-yl}-piperidin-1-ylmethyl)-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C36H46F4N4O3
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0493031
|
(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-phenoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
|
C39H47FN4O3
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0498847
|
(2R,4R)-2-[(2S,3S)-3-{4-[5-(4-Difluoromethoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C35H45F3N4O3
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0504893
|
(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-methyl-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C35H47FN4O2
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0541939
|
(R)-2-[(2S,3S)-3-{4-[5-(4-Cyclobutoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
|
C37H49FN4O3
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0190427
|
4-[5-[[4-[(5R)-5-(3-chlorophenyl)-3-(oxan-4-yl)-2-oxoimidazolidin-1-yl]piperidin-1-yl]methyl]-6-methylpyridin-2-yl]oxybenzoic acid
Show/Hide
|
C33H37ClN4O5
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0431308
|
N-ethyl-N-[1-[(3R)-3-(3-fluorophenyl)-3-(1-methylsulfonylpiperidin-4-yl)propyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C31H44FN3O5S2
|
1
|
| 1 |
IC50 = 0.68 nM
|
|
|
|
CP0497421
|
N-[1-[(3R)-3-(3-chloro-5-fluorophenyl)-3-(1-methylsulfonylpiperidin-4-yl)propyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C31H43ClFN3O5S2
|
1
|
| 1 |
IC50 = 0.69 nM
|
|
|
|
CP0217347
|
(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-isopropoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C37H51FN4O3
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0360002
|
(R)-2-[(2S,3S)-3-{4-[5-(4-Cyclobutoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C38H51FN4O3
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0408391
|
(R)-Cyclohexyl-[(2S,3S)-3-{4-[2-ethyl-5-(4-propoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-acetic acid
Show/Hide
|
C39H53FN4O3
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0469384
|
(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(3-methoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C35H47FN4O3
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0488130
|
(2R,4S)-2-[(2S,3S)-3-{4-[5-(4-Benzyloxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C41H51FN4O3
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0491833
|
(R)-2-[(2S,3S)-3-[4-(5-Benzo[1,3]dioxol-5-ylmethyl-2-ethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C35H45FN4O4
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0494588
|
(R)-2-[(2S,3S)-3-{4-[5-(4-Ethoxy-3-fluoro-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C36H48F2N4O3
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0509136
|
(2R,4S)-2-[(2S,3S)-3-{4-[5-(4-Ethoxy-3-fluoro-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C36H48F2N4O3
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0075166
|
4-[6-ethyl-5-[[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]pyridin-2-yl]oxybenzoic acid
Show/Hide
|
C34H40N4O5
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0438483
|
1-[1-[(3R)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-3-[(4-nitrophenyl)methyl]-1-prop-2-enylurea
Show/Hide
|
C33H41N5O5S
|
1
|
| 1 |
IC50 = 0.75 nM
|
|
|
|
CP0464348
|
(S)-N-ethyl-2-(4-(methylsulfonyl)phenyl)-N-(1-(3-(4-(methylsulfonyl)phenyl)-3-phenylpropyl)piperidin-4-yl)acetamide
Show/Hide
|
C32H40N2O5S2
|
1
|
| 1 |
IC50 = 0.76 nM
|
|
|
|
CP0403552
|
Allyl-{1-[(3S,4S)-1-(2-chloro-benzoyl)-4-phenyl-pyrrolidin-3-ylmethyl]-piperidin-4-yl}-carbamic acid 4-nitro-benzyl ester
Show/Hide
|
C34H37ClN4O5
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0530581
|
Allyl-{1-[(3S,4S)-1-(naphthalene-1-carbonyl)-4-phenyl-pyrrolidin-3-ylmethyl]-piperidin-4-yl}-carbamic acid 4-nitro-benzyl ester
Show/Hide
|
C38H40N4O5
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0539009
|
Allyl-[1-((3S,4S)-1-cyclohexanecarbonyl-4-phenyl-pyrrolidin-3-ylmethyl)-piperidin-4-yl]-carbamic acid 4-nitro-benzyl ester
Show/Hide
|
C34H44N4O5
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0528919
|
(3-carbamoylphenyl)methyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-(3-chlorophenyl)butyl]piperidin-4-yl]-N-propylcarbamate
Show/Hide
|
C34H43ClN4O5S
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0453222
|
(R)-3-Cyclobutyl-2-((3S,4S)-3-(3-fluoro-phenyl)-4-{4-[(4-methoxy-pyrimidin-2-yl)-propyl-amino]-piperidin-1-ylmethyl}-pyrrolidin-1-yl)-propionic acid
Show/Hide
|
C31H44FN5O3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0447716
|
(R)-2-((S)-3-(3-Fluoro-phenyl)-4-{4-[2-(4-fluoro-phenylsulfanyl)-ethyl]-piperidin-1-ylmethyl}-pyrrolidin-1-yl)-3-methyl-butyric acid
Show/Hide
|
C29H38F2N2O2S
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0490454
|
(R)-3-Cyclobutyl-2-((S)-3-(3-fluoro-phenyl)-4-{4-[3-(4-fluoro-phenyl)-propyl]-piperidin-1-ylmethyl}-pyrrolidin-1-yl)-propionic acid
Show/Hide
|
C32H42F2N2O2
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0454308
|
(3,5-dichloropyridin-4-yl)(4-methyl-4-(4-(phenyl(pyridin-3-yl)amino)piperidin-1-yl)piperidin-1-yl)methanone
Show/Hide
|
C28H31Cl2N5O
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0493276
|
(R)-3-Cyclobutyl-2-{(3S,4S)-3-(3-fluoro-phenyl)-4-[4-(6-phenyl-imidazo[1,2-a]pyridin-3-yl)-piperidin-1-ylmethyl]-pyrrolidin-1-yl}-propionic acid
Show/Hide
|
C36H41FN4O2
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0250959
|
(R)-2-((3S,4S)-3-((4-(3-benzyl-1-ethyl-1H-pyrazol-5-yl)piperidin-1-yl)methyl)-4-(3-fluorophenyl)pyrrolidin-1-yl)-3,3-dimethylbutanoic acid
Show/Hide
|
C34H45FN4O2
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0449246
|
(2R,3R)-2-[(2S,3S)-3-[4-(5-Benzyl-2-ethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C34H45FN4O2
|
2
|
| 1 |
IC50 = 0.8 nM
|
|
|
| 2 |
IC50 = 0.9 nM
|
|
|
|
CP0373376
|
(R)-2-[(2S,3S)-3-{4-[5-(3-Cyano-4-methoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
|
C35H44FN5O3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0375148
|
(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-propoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
|
C36H49FN4O3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0448273
|
(2R,4R)-2-[(2S,3S)-3-{4-[5-(3-Ethoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C36H49FN4O3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0487574
|
(2R,4R)-2-[(2S,3S)-3-{4-[5-(4-Butoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C38H53FN4O3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0492766
|
(2R,4R)-2-[(2S,3S)-3-{4-[5-(4-tert-Butyl-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C38H53FN4O2
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0501580
|
(R)-2-[(2S,3S)-3-{4-[5-(4-Butoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C38H53FN4O3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0504866
|
(R)-2-[(2S,3S)-3-{4-[5-(4-tert-Butoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
|
C37H51FN4O3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0511593
|
(R)-[(2S,3S)-3-{4-[5-(4-Butoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-cyclohexyl-acetic acid
Show/Hide
|
C40H55FN4O3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0524317
|
2-[3-{4-[2-Ethyl-5-(4-trifluoromethoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
|
C34H42F4N4O3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0535406
|
(R)-[(2S,3S)-3-{4-[5-(4-Benzenesulfonyl-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-cyclohexyl-acetic acid
Show/Hide
|
C42H51FN4O4S
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0541328
|
(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-propoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C37H51FN4O3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0542054
|
2-[3-{4-[2-Ethyl-5-(4-isopropoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C37H51FN4O3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0082990
|
(R)-3-Cyclobutyl-2-{(3S,4S)-3-(3-fluoro-phenyl)-4-[4-(6-trifluoromethyl-imidazo[1,2-a]pyridin-3-yl)-piperidin-1-ylmethyl]-pyrrolidin-1-yl}-propionic acid
Show/Hide
|
C31H36F4N4O2
|
1
|
| 1 |
IC50 = 0.82 nM
|
|
|
|
CP0395136
|
(R)-{(3S,4S)-3-[4-(3-Benzoimidazol-1-yl-propyl)-piperidin-1-ylmethyl]-4-phenyl-pyrrolidin-1-yl}-cyclohexyl-acetic acid
Show/Hide
|
C34H46N4O2
|
1
|
| 1 |
IC50 = 0.84 nM
|
|
|
|
CP0435532
|
(R)-2-[(3S,4S)-3-[4-(6-Chloro-imidazo[1,2-a]pyridin-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-cyclobutyl-propionic acid
Show/Hide
|
C30H36ClFN4O2
|
1
|
| 1 |
IC50 = 0.89 nM
|
|
|
|
CP0437396
|
(R)-2-[(S)-3-{4-[2-(4-Fluoro-benzenesulfonyl)-ethyl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
|
C29H38F2N2O4S
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0405004
|
(2,4-dimethylpyridin-3-yl)(4-methyl-4-(4-(phenyl(pyridin-3-yl)amino)piperidin-1-yl)piperidin-1-yl)methanone
Show/Hide
|
C30H37N5O
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0182721
|
(2R,3S)-2-[(2S,3S)-3-[4-(5-Benzyl-2-ethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C34H45FN4O2
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0417393
|
(R)-2-((3S,4S)-3-((4-(3-benzyl-1-ethyl-1H-pyrazol-5-yl)piperidin-1-yl)methyl)-4-(3-fluorophenyl)pyrrolidin-1-yl)-3-ethylpentanoic acid
Show/Hide
|
C35H47FN4O2
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0399726
|
(R)-[(2S,3S)-3-{4-[5-(4-Chloro-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-cyclohexyl-acetic acid
Show/Hide
|
C36H46ClFN4O2
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0399737
|
(2R,4S)-2-[(2S,3S)-3-{4-[5-(3-Ethoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C36H49FN4O3
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0432448
|
(R)-2-[(2S,3S)-3-{4-[5-(4-Ethoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C36H49FN4O3
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0487575
|
(R)-2-[(2S,3S)-3-{4-[5-(3-Cyano-4-methoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C36H46FN5O3
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0501594
|
(2R,4S)-2-[(2S,3S)-3-{4-[5-(3-Cyano-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C35H44FN5O2
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0539854
|
(R)-Cyclohexyl-[(2S,3S)-3-{4-[5-(3,5-difluoro-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-acetic acid
Show/Hide
|
C36H45F3N4O2
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0386293
|
methyl 2-(4-fluorophenyl)-2-[4-[2-[(1R,5S)-3-(2-methylbenzimidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl]ethyl]-4-phenylpiperidin-1-yl]acetate
Show/Hide
|
C37H43FN4O2
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0085221
|
4-[5-[[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]pyridin-2-yl]sulfanylbenzoic acid
Show/Hide
|
C32H36N4O4S
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0379587
|
6-chloro-N-[3-[4-[(5R)-3-(cyclohexylmethyl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
Show/Hide
|
C33H46ClN5O2
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0379630
|
6-chloro-N-[3-[4-(3-cyclohexyl-2-oxo-5-thiophen-3-ylimidazolidin-1-yl)piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
Show/Hide
|
C30H42ClN5O2S
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0379631
|
6-chloro-N-[3-[4-[(5R)-3-cyclopentyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
Show/Hide
|
C31H42ClN5O2
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0390787
|
4-[[5-[[4-[(5R)-5-(3-chlorophenyl)-3-(oxan-4-yl)-2-oxoimidazolidin-1-yl]piperidin-1-yl]methyl]-4-methylpyrimidin-2-yl]amino]benzoic acid
Show/Hide
|
C32H37ClN6O4
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0391972
|
4-[5-[[4-[(5R)-5-(3-chlorophenyl)-3-(oxan-4-yl)-2-oxoimidazolidin-1-yl]piperidin-1-yl]methyl]pyrimidin-2-yl]sulfanylbenzoic acid
Show/Hide
|
C31H34ClN5O4S
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0539714
|
1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmethyl)-4-{3-[4-(1H-tetrazol-5-ylmethyl)-phenyl]-propyl}-piperidin-4-ol
Show/Hide
|
C34H48N6O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0206396
|
(R)-Cyclohexyl-{(3S,4S)-3-[4-hydroxy-4-(3-phenyl-propyl)-piperidin-1-ylmethyl]-4-phenyl-pyrrolidin-1-yl}-acetic acid methyl ester
Show/Hide
|
C34H48N2O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0387903
|
(R)-2-((3S,4S)-3-((4-(2-benzyl-4-ethylthiazol-5-yl)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)-4-methylpentanoic acid
Show/Hide
|
C34H45N3O2S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0532405
|
(R)-N-(1-(3-(3-chlorophenyl)-3-(4-(methylsulfonyl)phenyl)propyl)piperidin-4-yl)-N-ethyl-2-(4-(methylsulfonyl)phenyl)acetamide
Show/Hide
|
C32H39ClN2O5S2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0867012
|
endo-1-(8-{2-[4-(3-Chlorophenyl)-1-(2,2-dimethylpropanoyl)piperidin-4-yl]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-2-methyl-1H-benzimidazole
Show/Hide
|
C33H43ClN4O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0433169
|
(4,6-Dimethyl-pyrimidin-5-yl)-(4-diphenylamino-4'-methyl-[1,4']bipiperidinyl-1'-yl)-methanone
Show/Hide
|
C30H37N5O
|
2
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
IC50 = 7.9 nM
|
|
|
|
CP0525661
|
(3,5-dichloro-1-oxy-pyridin-4-yl)-[4'-methyl-4-(phenyl-pyridin-3-yl-amino)-[1,4']bipiperidinyl-1'-yl]-methanone
Show/Hide
|
C28H31Cl2N5O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0466972
|
(2R)-3-cyclobutyl-2-[(3S,4S)-3-(3-fluorophenyl)-4-[(4-imidazo[1,2-a]pyrazin-3-ylpiperidin-1-yl)methyl]pyrrolidin-1-yl]propanoic acid
Show/Hide
|
C29H36FN5O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0873287
|
N-[1-[3-(4-cyanophenyl)-3-phenylpropyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C32H37N3O3S
|
1
|
| 1 |
IC50 < 1 nM
|
|
|
|
CP0430857
|
(R)-Cyclohexyl-[(2S,3S)-3-{4-[5-(4-ethoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-acetic acid
Show/Hide
|
C38H51FN4O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0448603
|
(R)-2-[(2S,3S)-3-{4-[5-(4-Ethoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
|
C35H47FN4O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0492247
|
(R)-2-[(2S,3S)-3-{4-[5-(4-Cyclopropoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
|
C36H47FN4O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0541341
|
(R)-2-[(2S,3S)-3-{4-[5-(3-Cyano-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C35H44FN5O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0543836
|
(R)-Cyclohexyl-[(2S,3S)-3-{4-[2-ethyl-5-(3-fluoro-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-acetic acid
Show/Hide
|
C36H46F2N4O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0543845
|
(2R,4S)-2-[(2S,3S)-3-{4-[5-(4-Butoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C38H53FN4O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0385612
|
6-chloro-2,4-dimethyl-N-[3-[4-[(5R)-2-oxo-5-phenyl-3-(pyridin-4-ylmethyl)imidazolidin-1-yl]piperidin-1-yl]butyl]pyridine-3-carboxamide
Show/Hide
|
C32H39ClN6O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0408996
|
4-[[(4R)-3-[1-[4-[(6-chloro-2,4-dimethylpyridine-3-carbonyl)amino]butan-2-yl]piperidin-4-yl]-2-oxo-4-phenylimidazolidin-1-yl]methyl]benzoic acid
Show/Hide
|
C34H40ClN5O4
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0093890
|
4-chlorobenzyl allyl(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-yl)carbamate
Show/Hide
|
C33H42ClN3O4
|
1
|
| 1 |
IC50 = 1.09 nM
|
|
|
|
CP0236508
|
1-allyl-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-yl)-3-(4-(trifluoromethyl)benzyl)urea
Show/Hide
|
C34H43F3N4O3
|
1
|
| 1 |
IC50 = 1.09 nM
|
|
|
|
CP0391414
|
(R)-3-Cyclobutyl-2-[(3S,4S)-3-[4-(cyclopropylmethyl-pyrimidin-2-yl-amino)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-propionic acid
Show/Hide
|
C31H42FN5O2
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0490164
|
(R)-Cyclohexyl-[(3S,4S)-3-{4-[2-(4-fluoro-benzenesulfonyl)-ethyl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-acetic acid
Show/Hide
|
C32H42F2N2O4S
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0542969
|
(R)-N-(1-(3-(3-chloro-5-fluorophenyl)-3-(4-(methylsulfonyl)phenyl)propyl)piperidin-4-yl)-N-ethyl-2-(4-(methylsulfonyl)phenyl)acetamide
Show/Hide
|
C32H38ClFN2O5S2
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0780614
|
(R)-1-butyl-3-((R)-cyclohexyl(hydroxy)methyl)-9-(4-phenoxybenzyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
|
C32H44ClN3O4
|
2
|
| 1 |
IC50 = 1.1 nM
|
|
|
| 2 |
IC50 = 53 nM
|
|
|
|
CP0112350
|
2-[3-{4-[2-Ethyl-5-(4-trifluoromethoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C35H44F4N4O3
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0373394
|
(R)-2-[(2S,3S)-3-[4-(5-Cyclohexylmethyl-2-ethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
|
C34H51FN4O2
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0391289
|
(2R,4R)-2-[(2S,3S)-3-{4-[5-(4-Benzenesulfonyl-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C40H49FN4O4S
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0393153
|
(2R,4S)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-propoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
|
C37H51FN4O3
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0399834
|
(R)-2-[(2S,3S)-3-{4-[5-(4-Benzenesulfonyl-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
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C40H49FN4O4S
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1
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| 1 |
IC50 = 1.1 nM
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CP0448599
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(R)-2-[(2S,3S)-3-{4-[5-(3,4-Difluoro-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
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C33H41F3N4O2
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1
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| 1 |
IC50 = 1.1 nM
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CP0492335
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(R)-Cyclohexyl-[(2S,3S)-3-{4-[2-ethyl-5-(4-fluoro-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-acetic acid
Show/Hide
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C36H46F2N4O2
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1
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| 1 |
IC50 = 1.1 nM
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CP0496239
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(R)-2-[(2S,3S)-3-{4-[5-(4-Benzyloxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
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C41H51FN4O3
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1
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| 1 |
IC50 = 1.1 nM
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CP0518129
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(R)-Cyclohexyl-[(2S,3S)-3-{4-[2-ethyl-5-(4-methoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-acetic acid
Show/Hide
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C37H49FN4O3
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1
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| 1 |
IC50 = 1.1 nM
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CP0537315
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(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-fluoro-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
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C33H42F2N4O2
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1
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| 1 |
IC50 = 1.1 nM
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CP0543835
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(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-hydroxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
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C34H45FN4O3
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1
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| 1 |
IC50 = 1.1 nM
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CP0495474
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N-ethyl-2-(4-methylsulfonylphenyl)-N-[1-[(3R)-3-(1-methylsulfonylpiperidin-4-yl)-3-phenylpropyl]piperidin-4-yl]acetamide
Show/Hide
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C31H45N3O5S2
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1
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| 1 |
IC50 = 1.1 nM
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CP0043064
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4-[6-methyl-5-[[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]pyridin-2-yl]oxybenzamide
Show/Hide
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C33H39N5O4
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1
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| 1 |
IC50 = 1.1 nM
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CP0391736
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6-chloro-2,4-dimethyl-N-[3-[4-[(5R)-3-(oxan-4-ylmethyl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]butyl]pyridine-3-carboxamide
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C32H44ClN5O3
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1
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| 1 |
IC50 = 1.1 nM
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CP0407517
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4-[6-methyl-5-[[4-[(5R)-5-(3-methylphenyl)-3-(oxan-4-yl)-2-oxoimidazolidin-1-yl]piperidin-1-yl]methyl]pyridin-2-yl]oxybenzoic acid
Show/Hide
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C34H40N4O5
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1
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| 1 |
IC50 = 1.1 nM
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CP0414860
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(R)-3-Cyclobutyl-2-{(3S,4S)-3-(3-fluoro-phenyl)-4-[4-(propyl-pyrimidin-4-yl-amino)-piperidin-1-ylmethyl]-pyrrolidin-1-yl}-propionic acid
Show/Hide
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C30H42FN5O2
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1
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| 1 |
IC50 = 1.2 nM
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CP0462908
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(R)-3-Cyclobutyl-2-((3S,4S)-3-(3-fluoro-phenyl)-4-{4-[propyl-(4-trifluoromethyl-pyrimidin-2-yl)-amino]-piperidin-1-ylmethyl}-pyrrolidin-1-yl)-propionic acid
Show/Hide
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C31H41F4N5O2
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1
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| 1 |
IC50 = 1.2 nM
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CP0219010
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(R)-2-((3S,4S)-3-((4-(3-benzyl-1-ethyl-1H-pyrazol-5-yl)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)-2-cyclohexylacetic acid
Show/Hide
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C36H48N4O2
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1
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| 1 |
IC50 = 1.2 nM
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CP0387905
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(R)-2-((3S,4S)-3-((4-(3-benzyl-1-ethyl-1H-pyrazol-5-yl)piperidin-1-yl)methyl)-4-(3-fluorophenyl)pyrrolidin-1-yl)-3-cyclopropylpropanoic acid
Show/Hide
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C34H43FN4O2
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1
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| 1 |
IC50 = 1.2 nM
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CP0401650
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(R)-2-((3S,4S)-3-((4-(3-benzyl-1-ethyl-1H-pyrazol-5-yl)piperidin-1-yl)methyl)-4-(3-fluorophenyl)pyrrolidin-1-yl)-3-cyclobutylpropanoic acid
Show/Hide
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C35H45FN4O2
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1
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| 1 |
IC50 = 1.2 nM
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CP0092301
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(R)-2-[(2S,3S)-3-{4-[5-(3,4-Dimethoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
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C36H49FN4O4
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1
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| 1 |
IC50 = 1.2 nM
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CP0409764
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(2R,4S)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(3-methoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
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C35H47FN4O3
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1
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| 1 |
IC50 = 1.2 nM
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CP0448169
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(2R,3S)-2-[(2S,3S)-3-[4-(5-Cyclohexylmethyl-2-ethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
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C34H51FN4O2
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1
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| 1 |
IC50 = 1.2 nM
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CP0497594
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(2R,4R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-propoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
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C37H51FN4O3
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1
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| 1 |
IC50 = 1.2 nM
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CP0441886
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1-acetyl-N-(3,4-dichlorophenyl)-N-[3-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]propyl]piperidine-4-carboxamide
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C29H36Cl2FN3O2
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1
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| 1 |
IC50 = 1.2 nM
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CP0413861
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N-[3-[4-[(5R)-3-benzyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]butyl]-6-chloro-2,4-dimethylpyridine-3-carboxamide
Show/Hide
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C33H40ClN5O2
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1
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| 1 |
IC50 = 1.2 nM
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CP0540420
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6-chloro-N-[(3R)-3-[4-[(5R)-3-cyclohexyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
Show/Hide
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C32H44ClN5O2
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1
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| 1 |
IC50 = 1.2 nM
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CP0236858
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(R)-2-((3S,4S)-3-((4-(2-benzylthiazol-4-yl)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)-2-cyclohexylacetic acid
Show/Hide
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C34H43N3O2S
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1
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| 1 |
IC50 = 1.3 nM
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CP0440554
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(4-methyl-4-(4-(phenyl(pyridin-3-yl)amino)piperidin-1-yl)piperidin-1-yl)(naphthalen-1-yl)methanone
Show/Hide
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C33H36N4O
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1
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| 1 |
IC50 = 1.3 nM
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CP0105713
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(R)-2-[(2S,3S)-3-{4-[5-(4-Cyano-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
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C35H44FN5O2
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1
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| 1 |
IC50 = 1.3 nM
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CP0268797
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(2R,4S)-2-[(2S,3S)-3-{4-[5-(4-Cyclobutoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
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C38H51FN4O3
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1
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| 1 |
IC50 = 1.3 nM
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CP0293817
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(2R,4S)-2-[(2S,3S)-3-{4-[5-(4-Cyano-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
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C35H44FN5O2
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1
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| 1 |
IC50 = 1.3 nM
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CP0383927
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(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-methoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
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C34H45FN4O3
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1
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| 1 |
IC50 = 1.3 nM
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CP0437119
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(R)-2-[(2S,3S)-3-{4-[5-(4-Benzenesulfonyl-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
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C39H47FN4O4S
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1
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| 1 |
IC50 = 1.3 nM
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CP0476054
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(2R,4S)-2-[(2S,3S)-3-{4-[5-(4-tert-Butoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
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C38H53FN4O3
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1
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| 1 |
IC50 = 1.3 nM
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CP0506451
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(R)-2-[(2S,3S)-3-{4-[5-(4-Chloro-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
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C33H42ClFN4O2
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1
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| 1 |
IC50 = 1.3 nM
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CP0535434
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(2R,4S)-2-[(2S,3S)-3-{4-[5-(4-Cyano-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
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C35H44FN5O2
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1
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| 1 |
IC50 = 1.3 nM
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CP0541322
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(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(3-fluoro-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
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C33H42F2N4O2
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1
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| 1 |
IC50 = 1.3 nM
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CP0375380
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N-methyl-4-[6-methyl-5-[[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]pyridin-2-yl]oxybenzamide
Show/Hide
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C34H41N5O4
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1
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| 1 |
IC50 = 1.3 nM
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CP0391973
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4-[5-[[4-[(5R)-5-(3-chlorophenyl)-3-(oxan-4-yl)-2-oxoimidazolidin-1-yl]piperidin-1-yl]methyl]pyridin-2-yl]oxybenzoic acid
Show/Hide
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C32H35ClN4O5
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1
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| 1 |
IC50 = 1.3 nM
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CP0514467
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1-allyl-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-(3-fluorophenyl)-4-hydroxypyrrolidin-3-yl)methyl)piperidin-4-yl)-3-(4-(trifluoromethyl)benzyl)urea
Show/Hide
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C34H42F4N4O3
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1
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| 1 |
IC50 = 1.38 nM
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CP0666580
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Dimethyl-(tetrahydro-pyran-4-yl)-{4-[(3-p-tolyl-8,9-dihydro-7H-benzocycloheptene-6-carbonyl)-amino]-benzyl}-ammonium chloride(TAK-779)
Show/Hide
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C33H39ClN2O2
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1
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| 1 |
IC50 = 1.4 nM
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CP0405009
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(4-(4-(benzyl(phenyl)amino)piperidin-1-yl)-4-methylpiperidin-1-yl)(2,6-dimethylphenyl)methanone
Show/Hide
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C33H41N3O
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2
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| 1 |
IC50 = 1.4 nM
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| 2 |
IC50 = 12.2 nM
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CP0399767
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(2R,4S)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-hydroxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
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C34H45FN4O3
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1
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| 1 |
IC50 = 1.4 nM
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CP0002124
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4,4-Difluoro-cyclohexanecarboxylic acid {(S)-3-[(1S,5S)-3-(3-isopropyl-5-methyl-[1,2,4]triazol-4-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-1-phenyl-propyl}-amide
Show/Hide
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C29H41F2N5O
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3
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| 1 |
IC50 = 1.4 nM
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| 2 |
IC50 = 13.1 nM
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| 3 |
IC50 = 25.43 nM
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CP0053415
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4-[6-methyl-5-[[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]pyridin-2-yl]oxybenzoic acid
Show/Hide
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C33H38N4O5
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1
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| 1 |
IC50 = 1.4 nM
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CP0249043
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(4-nitrophenyl)methyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-propylcarbamate
Show/Hide
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C33H42N4O6S
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1
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| 1 |
IC50 = 1.5 nM
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CP0263078
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Allyl-{1-[(S)-4-(benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-carbamic acid benzyl ester
Show/Hide
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C33H41N3O4S
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1
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| 1 |
IC50 = 1.5 nM
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CP0922051
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{1-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-propyl-carbamic acid 4-nitro-benzyl ester
Show/Hide
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C33H42N4O6S
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1
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| 1 |
IC50 = 1.5 nM
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CP0406280
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(R)-3-Cyclobutyl-2-[(3S,4S)-3-[4-(ethyl-pyrimidin-2-yl-amino)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-propionic acid
Show/Hide
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C29H40FN5O2
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1
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| 1 |
IC50 = 1.5 nM
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CP0492654
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(2R)-3-cyclopropyl-2-((3S,4S)-3-(3-fluorophenyl)-4-((4-(3-(4-fluorophenyl)-4-methoxy-4-oxobutyl)piperidin-1-yl)methyl)pyrrolidin-1-yl)propanoic acid
Show/Hide
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C33H42F2N2O4
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1
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| 1 |
IC50 = 1.5 nM
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CP0042563
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(R)-2-((3S,4S)-3-((4-(3-benzyl-1-ethyl-1H-pyrazol-5-yl)piperidin-1-yl)methyl)-4-(3-fluorophenyl)pyrrolidin-1-yl)-3-methylbutanoic acid
Show/Hide
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C33H43FN4O2
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1
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| 1 |
IC50 = 1.5 nM
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CP0345860
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(R)-2-((3S,4S)-3-((4-(5-benzyloxazol-2-yl)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)-2-cyclohexylacetic acid
Show/Hide
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C34H43N3O3
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1
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| 1 |
IC50 = 1.5 nM
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CP0129911
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(2R,4S)-2-[(2S,3S)-3-{4-[5-(3,4-Dimethoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
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C36H49FN4O4
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1
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| 1 |
IC50 = 1.5 nM
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CP0376763
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(R)-Cyclohexyl-[(2S,3S)-3-{4-[2-ethyl-5-(4-trifluoromethyl-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-acetic acid
Show/Hide
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C37H46F4N4O2
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1
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| 1 |
IC50 = 1.5 nM
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CP0447714
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(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-methoxy-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
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C35H47FN4O3
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1
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| 1 |
IC50 = 1.5 nM
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CP0535429
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(R)-Cyclohexyl-[(2S,3S)-3-{4-[5-(2,4-difluoro-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-acetic acid
Show/Hide
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C36H45F3N4O2
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1
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| 1 |
IC50 = 1.5 nM
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CP0462246
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4-[5-[[4-[(5R)-5-(3-fluorophenyl)-3-(oxan-4-yl)-2-oxoimidazolidin-1-yl]piperidin-1-yl]methyl]-6-methylpyridin-2-yl]oxybenzoic acid
Show/Hide
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C33H37FN4O5
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1
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| 1 |
IC50 = 1.5 nM
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CP0191326
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N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-2-[4-(methylsulfamoyl)phenyl]-N-prop-2-enylacetamide
Show/Hide
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C34H46N4O5S
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1
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| 1 |
IC50 = 1.53 nM
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CP0502495
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(R)-Cyclohexyl-{(3S,4S)-3-(3-fluoro-phenyl)-4-[4-(propyl-pyrimidin-2-yl-amino)-piperidin-1-ylmethyl]-pyrrolidin-1-yl}-acetic acid
Show/Hide
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C31H44FN5O2
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1
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| 1 |
IC50 = 1.6 nM
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CP0460168
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(R)-Cyclohexyl-((3S,4S)-3-{4-[3-(4-fluoro-phenyl)-3-oxo-propyl]-piperidin-1-ylmethyl}-4-phenyl-pyrrolidin-1-yl)-acetic acid
Show/Hide
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C33H43FN2O3
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1
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| 1 |
IC50 = 1.6 nM
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CP0475108
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(2R)-3-cyclopropyl-2-((3S,4S)-3-(3-fluorophenyl)-4-((4-(3-(4-fluorophenyl)-3-hydroxybutyl)piperidin-1-yl)methyl)pyrrolidin-1-yl)propanoic acid
Show/Hide
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C32H42F2N2O3
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1
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| 1 |
IC50 = 1.6 nM
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CP0303470
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(R)-2-((3S,4S)-3-((4-(2-benzyloxazol-5-yl)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)-3-cyclopropylpropanoic acid
Show/Hide
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C32H39N3O3
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1
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| 1 |
IC50 = 1.6 nM
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CP0496319
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(R)-2-((3S,4S)-3-((4-(3-benzyl-1-ethyl-1H-pyrazol-5-yl)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)-2-cyclobutylacetic acid
Show/Hide
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C34H44N4O2
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1
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| 1 |
IC50 = 1.6 nM
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CP0395197
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(R)-[(2S,3S)-3-[4-(5-Benzyl-2-ethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-cyclohexyl-acetic acid
Show/Hide
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C36H47FN4O2
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1
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| 1 |
IC50 = 1.6 nM
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CP0544842
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2-[3-[4-(5-Benzyl-2-ethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-2,3-dimethyl-butyric acid
Show/Hide
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C34H45FN4O2
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1
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| 1 |
IC50 = 1.6 nM
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CP0046286
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(2R,4R)-2-[(2S,3S)-3-{4-[5-(4-tert-Butoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
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C38H53FN4O3
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1
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| 1 |
IC50 = 1.6 nM
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CP0166453
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(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-methanesulfonyl-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
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C35H47FN4O4S
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1
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| 1 |
IC50 = 1.6 nM
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CP0514595
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(2R,4R)-2-[(2S,3S)-3-{4-[5-(3,5-Bis-trifluoromethyl-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
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C36H43F7N4O2
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1
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| 1 |
IC50 = 1.6 nM
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CP0417040
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N-ethyl-2-(4-methylsulfonylphenyl)-N-[1-[(3S)-3-phenyl-3-[4-(trifluoromethylsulfonyl)piperazin-1-yl]propyl]piperidin-4-yl]acetamide
Show/Hide
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C30H41F3N4O5S2
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1
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| 1 |
IC50 = 1.6 nM
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CP0399207
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1-allyl-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-yl)-3-(2,4-difluorobenzyl)urea
Show/Hide
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C33H42F2N4O3
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1
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| 1 |
IC50 = 1.62 nM
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CP0520984
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1-allyl-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-yl)-3-(3,4-difluorobenzyl)urea
Show/Hide
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C33H42F2N4O3
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1
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| 1 |
IC50 = 1.69 nM
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CP0495681
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(R)-3-Cyclobutyl-2-{(3S,4S)-3-(3-fluoro-phenyl)-4-[4-(propyl-pyrimidin-5-yl-amino)-piperidin-1-ylmethyl]-pyrrolidin-1-yl}-propionic acid
Show/Hide
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C30H42FN5O2
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1
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| 1 |
IC50 = 1.7 nM
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CP0394011
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N-ethyl-2-(4-methylsulfonylphenyl)-N-[1-[3-(4-methylsulfonylphenyl)-3-phenylpropyl]piperidin-4-yl]acetamide
Show/Hide
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C32H40N2O5S2
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1
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| 1 |
IC50 = 1.7 nM
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CP0869198
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(S)-(-)-8-{4-[2-(butoxy)ethoxy]phenyl}-1-propyl-N-(4-{[(1-propyl-1H-imidazol-5-yl)methyl]sulfinyl}phenyl)-1,2,3,4-tetrahydro-1-benzazocine-5-carboxamide
Show/Hide
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C40H50N4O4S
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1
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| 1 |
IC50 = 1.7 nM
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CP0871030
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(S)-(-)-8-{4-[2-(butoxy)ethoxy]phenyl}-1-[(1-methyl-1H-pyrazol-4-yl)methyl]-N-(4-{[(1-propyl-1H-imidazol-5-yl)methyl]-sulfinyl}phenyl)-1,2,3,4-tetrahydro-1-benzazocine-5-carboxamide
Show/Hide
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C42H50N6O4S
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1
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| 1 |
IC50 = 1.7 nM
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CP0405008
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2,4-dimethyl-1-oxy-pyridin-3-yl)-{4'-methyl-4-[(2-methyl-thiazol-4-ylmethyl)-phenyl-amino]-[1,4']bipiperidinyl-1'-yl}-methanone
Show/Hide
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C30H39N5O2S
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1
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| 1 |
IC50 = 1.7 nM
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CP0497633
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(R)-[(2S,3S)-3-{4-[5-(4-Cyano-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-cyclohexyl-acetic acid
Show/Hide
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C37H46FN5O2
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1
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| 1 |
IC50 = 1.7 nM
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CP0506568
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(R)-2-[(2S,3S)-3-{4-[5-(3-Cyano-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
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C34H42FN5O2
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1
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| 1 |
IC50 = 1.7 nM
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CP0435461
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N-[3-[4-[(4-cyanophenyl)methyl]piperidin-1-yl]propyl]-N-(3,4-dichlorophenyl)-1-methylsulfonylpiperidine-4-carboxamide
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C29H36Cl2N4O3S
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1
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| 1 |
IC50 = 1.7 nM
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CP0523077
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1-acetyl-N-(3,4-dichlorophenyl)-N-(3-{4-[(4-fluorophenyl)sulfanyl]piperidin-1-yl}propyl)piperidine-4-carboxamide
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C28H34Cl2FN3O2S
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1
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| 1 |
IC50 = 1.7 nM
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CP0407515
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6-chloro-2,4-dimethyl-N-[3-[4-[(5R)-3-[(4-methylpyridin-3-yl)methyl]-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]butyl]pyridine-3-carboxamide
Show/Hide
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C33H41ClN6O2
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1
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| 1 |
IC50 = 1.7 nM
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CP0409022
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(4R)-1-cyclohexyl-3-[1-[1-(4,6-dimethylpyrimidine-5-carbonyl)-4-methylpiperidin-4-yl]piperidin-4-yl]-4-phenylimidazolidin-2-one
Show/Hide
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C33H46N6O2
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1
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| 1 |
IC50 = 1.7 nM
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CP0413840
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6-chloro-N-[3-[4-[(5R)-3-cyclobutyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
Show/Hide
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C30H40ClN5O2
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1
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| 1 |
IC50 = 1.7 nM
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CP0066237
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1-allyl-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-yl)-3-(4-fluorobenzyl)urea
Show/Hide
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C33H43FN4O3
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1
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| 1 |
IC50 = 1.71 nM
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CP0430184
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(R)-3-Cyclobutyl-2-{(3S,4S)-3-(3-fluoro-phenyl)-4-[4-(propyl-pyrimidin-2-yl-amino)-piperidin-1-ylmethyl]-pyrrolidin-1-yl}-propionic acid
Show/Hide
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C30H42FN5O2
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1
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| 1 |
IC50 = 1.8 nM
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CP0509933
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(2,4-dimethyl-1-oxy-pyridin-3-yl)-[4'-methyl-4-(phenyl-pyridin-2-yl-amino)-[1,4']bipiperidinyl-1'-yl]-methanone
Show/Hide
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C30H37N5O2
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1
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| 1 |
IC50 = 1.8 nM
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CP0424888
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7-(4-(2-butoxyethoxy)phenyl)-1-isobutyl-N-(4-((1-propyl-1H-imidazol-5-yl)methylsulfinyl)phenyl)-2,3-dihydro-1H-benzo[b]azepine-4-carboxamide
Show/Hide
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C40H50N4O4S
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1
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| 1 |
IC50 = 1.9 nM
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CP0460073
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benzyl N-[1-[[(3S,4S)-1-(cyclopentanecarbonyl)-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-ethylcarbamate
Show/Hide
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C32H43N3O3
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1
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| 1 |
IC50 = 2 nM
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CP0530018
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benzyl N-[1-[[(3S,4S)-1-(2-chlorobenzoyl)-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-ethylcarbamate
Show/Hide
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C33H38ClN3O3
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1
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| 1 |
IC50 = 2 nM
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CP0647821
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(1-{3-(3-Chloro-phenyl)-4-[(R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-imidazolidin-1-yl]-butyl}-piperidin-4-yl)-ethyl-carbamic acid benzyl ester
Show/Hide
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C37H42ClN5O4
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1
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| 1 |
IC50 = 2 nM
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CP0075157
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Allyl-{1-[(S)-4-(benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-carbamic acid 4-nitro-benzyl ester
Show/Hide
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C33H40N4O6S
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1
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| 1 |
IC50 = 2 nM
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CP0076425
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(4-carbamoylphenyl)methyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-propylcarbamate
Show/Hide
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C34H44N4O5S
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1
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| 1 |
IC50 = 2 nM
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CP0315852
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benzyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-ethylcarbamate
Show/Hide
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C32H41N3O4S
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2
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| 1 |
IC50 = 2 nM
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| 2 |
IC50 = 7 nM
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CP0372702
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N-[1-[(3R)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-2-(4-nitrophenyl)-N-prop-2-enylacetamide
Show/Hide
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C33H40N4O5S
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1
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| 1 |
IC50 = 2 nM
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CP0376456
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benzyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-(3-chlorophenyl)butyl]piperidin-4-yl]-N-ethylcarbamate
Show/Hide
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C32H40ClN3O4S
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1
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| 1 |
IC50 = 2 nM
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CP0460941
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benzyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-propylcarbamate
Show/Hide
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C33H43N3O4S
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1
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| 1 |
IC50 = 2 nM
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CP0507592
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Allyl-{1-[(S)-4-(benzenesulfonyl-methyl-amino)-3-(3-chloro-phenyl)-butyl]-piperidin-4-yl}-carbamic acid 4-nitro-benzyl ester
Show/Hide
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C33H39ClN4O6S
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1
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| 1 |
IC50 = 2 nM
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CP0947402
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Allyl-{1-[(S)-4-(benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-piperidin-4-yl}-carbamic acid benzyl ester
Show/Hide
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C33H41N3O4S
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1
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| 1 |
IC50 = 2 nM
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CP0445216
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3-(4-{3-[1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmethyl)-4-hydroxy-piperidin-4-yl]-propyl}-phenyl)-propionic acid
Show/Hide
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C35H50N2O3
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1
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| 1 |
IC50 = 2 nM
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CP0206593
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(R)-2-((3S,4S)-3-((4-hydroxy-4-(3-phenylpropyl)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)-3-methylbutanoic acid
Show/Hide
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C30H42N2O3
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1
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| 1 |
IC50 = 2 nM
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CP0328166
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(R)-2-((3S,4S)-3-((4-(5-benzylthiazol-2-yl)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)-2-cyclohexylacetic acid
Show/Hide
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C34H43N3O2S
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1
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| 1 |
IC50 = 2 nM
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CP0377973
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[4-[4-(N-benzylanilino)piperidin-1-yl]-4-methylpiperidin-1-yl]-(2,4-dimethyl-1-oxidopyridin-1-ium-3-yl)methanone
Show/Hide
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C32H40N4O2
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2
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| 1 |
IC50 = 2 nM
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| 2 |
IC50 = 14.9 nM
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CP0484065
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(2,6-dimethylphenyl)(4-methyl-4-(4-(phenyl(pyridin-4-yl)amino)piperidin-1-yl)piperidin-1-yl)methanone
Show/Hide
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C31H38N4O
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1
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| 1 |
IC50 = 2 nM
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CP0391288
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(R)-2-[(2S,3S)-3-{4-[5-(4-tert-Butoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
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C38H53FN4O3
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1
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| 1 |
IC50 = 2 nM
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CP0511260
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(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-trifluoromethyl-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
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C34H42F4N4O2
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1
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| 1 |
IC50 = 2 nM
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CP0398592
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(E)-methyl N-cyano-4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)-4-phenylpiperidine-1-carbimidate
Show/Hide
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C31H38N6O
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1
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| 1 |
IC50 = 2 nM
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CP0492246
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(2R,4S)-2-[(2S,3S)-3-{4-[5-(3,5-Bis-trifluoromethyl-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
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C36H43F7N4O2
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1
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| 1 |
IC50 = 2.1 nM
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CP0090929
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N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-prop-2-enyl-2-(4-sulfamoylphenyl)acetamide
Show/Hide
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C33H44N4O5S
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1
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| 1 |
IC50 = 2.1 nM
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CP0883433
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(S)-(-)-8-{4-[2-(butoxy)ethoxy]phenyl}-1-propyl-N-(4-{[(4-propyl-4H-1,2,4-tri azol-3-yl)methyl]sulfinyl}phenyl)-1,2,3,4-tetrahydro-1-benzazocine-5-carboxamide
Show/Hide
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C39H49N5O4S
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1
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| 1 |
IC50 = 2.2 nM
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CP0514594
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(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(2-fluoro-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
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C33H42F2N4O2
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1
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| 1 |
IC50 = 2.2 nM
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CP0439500
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N-(3,4-dichlorophenyl)-1-methylsulfonyl-N-[3-[4-[(4-methylsulfonylphenyl)methyl]piperidin-1-yl]propyl]piperidine-4-carboxamide
Show/Hide
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C29H39Cl2N3O5S2
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1
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| 1 |
IC50 = 2.2 nM
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CP0405005
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(2,4-Dimethyl-pyridin-3-yl)-(4-diphenylamino-4'-methyl-[1,4']bipiperidinyl-1'-yl)-methanone
Show/Hide
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C31H38N4O
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2
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| 1 |
IC50 = 2.3 nM
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| 2 |
IC50 = 11 nM
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CP0502591
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N-ethyl-2-(4-methylsulfonylphenyl)-N-[1-[3-phenyl-3-[4-(trifluoromethyl)phenyl]propyl]piperidin-4-yl]acetamide
Show/Hide
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C32H37F3N2O3S
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1
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| 1 |
IC50 = 2.3 nM
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CP0373621
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(R)-2-[(2S,3S)-3-{4-[5-(3,5-Bis-trifluoromethyl-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3,3-dimethyl-butyric acid
Show/Hide
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C36H43F7N4O2
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1
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| 1 |
IC50 = 2.3 nM
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CP0493796
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(R)-2-[(2S,3S)-3-[4-(5-Cyclohexylmethyl-2-ethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
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C33H49FN4O2
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1
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| 1 |
IC50 = 2.3 nM
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CP0514596
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(R)-Cyclohexyl-[(2S,3S)-3-{4-[2-ethyl-5-(4-methanesulfonyl-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-acetic acid
Show/Hide
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C37H49FN4O4S
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1
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| 1 |
IC50 = 2.3 nM
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CP0849521
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(S)-(-)-8-{4-[2-(butoxy)ethoxy]phenyl}-1-isobutyl-N-(4-{[(4-propyl-4H-1,2,4-triazol-3-yl)methyl]sulfinyl}phenyl)-1,2,3,4-tetrahydro-1-benzazocine-5-carboxamide
Show/Hide
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C40H51N5O4S
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1
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| 1 |
IC50 = 2.4 nM
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CP0438155
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N-ethyl-N-[1-[3-(1-ethylsulfonylpiperidin-4-yl)-3-phenylpropyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C32H47N3O5S2
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1
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| 1 |
IC50 = 2.4 nM
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CP0528662
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1-[1-[4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-3-benzyl-1-propylurea
Show/Hide
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C33H44N4O3S
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1
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| 1 |
IC50 = 2.5 nM
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CP0501156
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Allyl-[1-((2S,3aS,4S,5S)-2,4-diphenyl-hexahydro-pyrrolo[1,2-b]isoxazol-5-ylmethyl)-piperidin-4-yl]-carbamic acid 4-nitro-benzyl ester
Show/Hide
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C35H40N4O5
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1
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| 1 |
IC50 = 2.5 nM
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CP0418975
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(R)-2-((3S,4S)-3-((4-(1H-benzo[d]imidazol-1-yl)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)-2-cyclohexylacetic acid
Show/Hide
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C31H40N4O2
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1
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| 1 |
IC50 = 2.5 nM
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CP0467620
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N-[3-[4-[5-(3-chlorophenyl)-3-cyclohexyl-2-oxoimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
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C31H43ClN6O2
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1
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| 1 |
IC50 = 2.5 nM
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CP0405010
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(2,6-Dimethyl-phenyl)-(4-diphenylamino-4'-methyl-[1,4']bipiperidinyl-1'-yl)-methanone
Show/Hide
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C32H39N3O
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2
|
| 1 |
IC50 = 2.6 nM
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| 2 |
IC50 = 15.3 nM
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CP0485449
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(R)-{(3S,4S)-3-[4-(2-Benzoimidazol-1-yl-ethyl)-piperidin-1-ylmethyl]-4-phenyl-pyrrolidin-1-yl}-cyclohexyl-acetic acid
Show/Hide
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C33H44N4O2
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1
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| 1 |
IC50 = 2.6 nM
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CP0264310
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(2R,4R)-2-[(2S,3S)-3-{4-[5-(3,4-Dimethoxy-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
Show/Hide
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C36H49FN4O4
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1
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| 1 |
IC50 = 2.6 nM
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CP0448180
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(R)-2-[(2S,3S)-3-{4-[5-(3,5-Difluoro-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
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C33H41F3N4O2
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1
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| 1 |
IC50 = 2.6 nM
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CP0093892
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1-allyl-3-(4-chlorobenzyl)-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
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C33H43ClN4O3
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1
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| 1 |
IC50 = 2.66 nM
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CP0496238
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(2R,3R)-2-[(3S,4S)-3-[[4-[5-[[3-(aminomethyl)phenyl]methyl]-2-ethylpyrazol-3-yl]piperidin-1-yl]methyl]-4-(3-fluorophenyl)pyrrolidin-1-yl]-3-methylpentanoic acid
Show/Hide
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C35H48FN5O2
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1
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| 1 |
IC50 = 2.7 nM
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CP0395137
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(R)-2-((3S,4S)-3-((4-(3H-imidazo[4,5-b]pyridin-3-yl)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)-2-cyclohexylacetic acid
Show/Hide
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C30H39N5O2
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1
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| 1 |
IC50 = 2.8 nM
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CP0449506
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N-[3-[4-[(3-carbamoylphenyl)methyl]piperidin-1-yl]propyl]-N-(3,4-dichlorophenyl)-1-methylsulfonylpiperidine-4-carboxamide
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C29H38Cl2N4O4S
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1
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| 1 |
IC50 = 2.8 nM
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CP0398191
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(4,6-dimethyl-1-oxy-pyrimidin-5-yl)-(4-diphenylamino-4'-methyl-[1,4']bipiperidinyl-1'-yl)-methanone
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C30H37N5O2
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2
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| 1 |
IC50 = 2.9 nM
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| 2 |
IC50 = 24 nM
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CP0436922
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1-acetyl-N-(3,4-dichlorophenyl)-N-(3-{4-[(4-fluorophenyl)sulfonyl]piperidin-1-yl}propyl)piperidine-4-carboxamide
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C28H34Cl2FN3O4S
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1
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| 1 |
IC50 = 2.9 nM
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CP0297705
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(4-nitrophenyl)methyl N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-prop-2-enylcarbamate
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C33H42N4O6
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2
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| 1 |
IC50 = 2.9 nM
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| 2 |
IC50 = 3.5 nM
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CP0278565
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4-((3-allyl-3-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-yl)ureido)methyl)-N-methylbenzenesulfonamide
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C34H47N5O5S
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1
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| 1 |
IC50 = 2.93 nM
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CP0514469
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N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-(3-fluorophenyl)-4-hydroxypyrrolidin-3-yl]methyl]piperidin-4-yl]-2-[4-(methylsulfamoyl)phenyl]-N-prop-2-enylacetamide
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C34H45FN4O5S
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1
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| 1 |
IC50 = 2.98 nM
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CP0654194
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Allyl-(1-{3-(3-chloro-phenyl)-4-[(R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-imidazolidin-1-yl]-butyl}-piperidin-4-yl)-carbamic acid benzyl ester
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C38H42ClN5O4
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1
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| 1 |
IC50 = 3 nM
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CP0151705
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(4-methylphenyl)methyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-propylcarbamate
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C34H45N3O4S
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1
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| 1 |
IC50 = 3 nM
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CP0263076
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(3-methylphenyl)methyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-propylcarbamate
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C34H45N3O4S
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1
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| 1 |
IC50 = 3 nM
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CP0501160
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(4-carbamoylphenyl)methyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-(3-chlorophenyl)butyl]piperidin-4-yl]-N-propylcarbamate
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C34H43ClN4O5S
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1
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| 1 |
IC50 = 3 nM
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CP0511110
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N-[1-[(3R)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-2-phenyl-N-propylacetamide
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C33H43N3O3S
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1
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| 1 |
IC50 = 3 nM
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CP0432391
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3-(3-(1-(((3S,4S)-1-(cyclohexylmethyl)-4-phenylpyrrolidin-3-yl)methyl)-4-hydroxypiperidin-4-yl)propyl)benzoic acid
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C33H46N2O3
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1
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| 1 |
IC50 = 3 nM
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CP0503820
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(R)-3-cyclobutyl-2-((3S,4S)-3-(3-fluorophenyl)-4-((4-(imidazo[1,2-b]pyridazin-3-yl)piperidin-1-yl)methyl)pyrrolidin-1-yl)propanoic acid
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C29H36FN5O2
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1
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| 1 |
IC50 = 3 nM
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CP0398590
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1-(8-(2-(1-(furan-2-ylmethyl)-4-phenylpiperidin-4-yl)ethyl)-8-azabicyclo[3.2.1]octan-3-yl)-2-methyl-1H-benzo[d]imidazole
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C33H40N4O
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1
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| 1 |
IC50 = 3 nM
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CP0474273
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2-(2,3-dimethylphenyl)-2-(4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)-4-phenylpiperidin-1-yl)acetic acid
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C38H46N4O2
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1
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| 1 |
IC50 = 3 nM
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CP0522782
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(E)-isopropyl N-cyano-4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)-4-phenylpiperidine-1-carbimidate
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C33H42N6O
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1
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| 1 |
IC50 = 3 nM
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CP0498558
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1-acetyl-N-(3-chloro-4-methylphenyl)-N-[3-[(2S)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]propyl]piperidine-4-carboxamide
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C30H40ClFN4O2
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1
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| 1 |
IC50 = 3 nM
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CP0871032
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CENICRIVIROC MESYLATE
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C42H56N4O7S2
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1
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| 1 |
IC50 = 3.1 nM
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CP0514599
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(R)-2-[(2S,3S)-3-{4-[5-(4-Cyano-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
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C34H42FN5O2
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1
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| 1 |
IC50 = 3.1 nM
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CP0492371
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N-ethyl-N-[1-[3-[4-(3-fluorophenyl)piperazin-1-yl]-3-phenylpropyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
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C35H45FN4O3S
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1
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| 1 |
IC50 = 3.1 nM
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CP0399833
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(R)-2-[(2S,3S)-3-{4-[5-(3,5-Bis-trifluoromethyl-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
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C35H41F7N4O2
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1
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| 1 |
IC50 = 3.2 nM
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CP0449507
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1-acetyl-N-(3,4-dichlorophenyl)-N-(3-{4-[(4-fluorophenyl)-sulfinyl]piperidin-1-yl}propyl)piperidine-4-carboxamide
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C28H34Cl2FN3O3S
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1
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| 1 |
IC50 = 3.2 nM
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CP0090926
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1-allyl-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-yl)-3-(4-nitrobenzyl)urea
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C33H43N5O5
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1
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| 1 |
IC50 = 3.2 nM
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CP0403557
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(2,4-Dimethyl-1-oxy-pyridin-3-yl)-(4-diphenylamino-4'-methyl-[1,4']bipiperidinyl-1'-yl)-methanone
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C31H38N4O2
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2
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| 1 |
IC50 = 3.3 nM
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| 2 |
IC50 = 16 nM
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CP0449508
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N-(3,4-dichlorophenyl)-N-[3-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]propyl]-1-methylsulfonylpiperidine-4-carboxamide
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C28H36Cl2FN3O3S
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1
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| 1 |
IC50 = 3.3 nM
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CP0093895
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N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-2-[4-(dimethylsulfamoyl)phenyl]-N-prop-2-enylacetamide
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C35H48N4O5S
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1
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| 1 |
IC50 = 3.32 nM
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CP0423593
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(R)-3-cyclobutyl-2-((3S,4S)-3-(3-fluorophenyl)-4-((4-(imidazo[1,2-a]pyrimidin-3-yl)piperidin-1-yl)methyl)pyrrolidin-1-yl)propanoic acid
Show/Hide
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C29H36FN5O2
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1
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| 1 |
IC50 = 3.5 nM
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CP0780617
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(R)-1-butyl-3-((R)-1-hydroxy-2-methylpropyl)-9-(4-phenoxybenzyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
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C29H40ClN3O4
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3
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| 1 |
IC50 = 3.5 nM
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| 2 |
IC50 = 33 nM
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| 3 |
IC50 = 84 nM
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CP0543837
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(R)-2-[(2S,3S)-3-{4-[2-Ethyl-5-(4-methanesulfonyl-benzyl)-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
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C34H45FN4O4S
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1
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| 1 |
IC50 = 3.5 nM
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CP0390640
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1-acetyl-N-{3-[4-(4-carbamoylbenzyl)piperidin-1-yl]propyl}-N-(3-chloro-4-methylphenyl)piperidine-4-carboxamide
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C31H41ClN4O3
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1
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| 1 |
IC50 = 3.5 nM
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CP0242684
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N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-2-phenyl-N-prop-2-enylacetamide
Show/Hide
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C33H43N3O3
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1
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| 1 |
IC50 = 3.5 nM
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CP0524922
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N-ethyl-2-(4-methylsulfonylphenyl)-N-[1-[(3R)-3-(1-methylsulfonylpiperidin-4-yl)-3-[3-(trifluoromethyl)phenyl]propyl]piperidin-4-yl]acetamide
Show/Hide
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C32H44F3N3O5S2
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1
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| 1 |
IC50 = 3.5 nM
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CP0431527
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5-[(R)-4-(Benzenesulfonyl-methyl-amino)-3-methyl-3-phenyl-butyl]-octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid 4-nitro-benzyl ester
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C33H40N4O6S
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1
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| 1 |
IC50 = 3.6 nM
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CP0265489
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2-(4-chlorophenyl)-N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-prop-2-enylacetamide
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C33H42ClN3O3
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1
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| 1 |
IC50 = 3.6 nM
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CP0373702
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3-Cyclopropyl-2-[(3S,4S)-3-((R)-3-fluoro-phenyl)-4-(4-{2-[2-(4-fluoro-phenyl)-[1,3]dioxolan-2-yl]-ethyl}-piperidin-1-ylmethyl)-pyrrolidin-1-yl]-propionic acid
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C33H42F2N2O4
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1
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| 1 |
IC50 = 3.7 nM
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CP0532106
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1-acetyl-N-{3-[4-(4-carbamoylbenzyl)piperidin-1-yl]propyl}-N-(3,4-dichlorophenyl)piperidine-4-carboxamide
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C30H38Cl2N4O3
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1
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| 1 |
IC50 = 3.8 nM
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CP0391724
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N-[3-[4-[(5R)-3-tert-butyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]butyl]-6-chloro-2,4-dimethylpyridine-3-carboxamide
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C30H42ClN5O2
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1
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| 1 |
IC50 = 3.8 nM
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CP0497900
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(R)-Cyclohexyl-{(3S,4S)-3-phenyl-4-[4-(propyl-pyridin-2-yl-amino)-piperidin-1-ylmethyl]-pyrrolidin-1-yl}-acetic acid
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C32H46N4O2
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1
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| 1 |
IC50 = 3.9 nM
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CP0415990
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(2R)-2-cyclohexyl-2-[(3S,4S)-3-[[4-[2-ethyl-5-(pyridin-3-ylmethyl)pyrazol-3-yl]piperidin-1-yl]methyl]-4-(3-fluorophenyl)pyrrolidin-1-yl]acetic acid
Show/Hide
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C35H46FN5O2
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1
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| 1 |
IC50 = 3.9 nM
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CP0514470
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4-((3-allyl-3-((1R,3S,5S)-8-(((3S,4R)-1-(cyclopentanecarbonyl)-4-(3-fluorophenyl)-4-hydroxypyrrolidin-3-yl)methyl)-8-azabicyclo[3.2.1]octan-3-yl)ureido)methyl)-N-methylbenzenesulfonamide
Show/Hide
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C36H48FN5O5S
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1
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| 1 |
IC50 = 3.98 nM
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CP0401669
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Benzyl (S)-2-(3,4-dichloro-phenyl)-4-(spiro[1-benzothiophene-3,4'-piperidinyl])butyl ester
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C29H31Cl2NO2S
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1
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| 1 |
IC50 = 4 nM
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CP0511250
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Benzoic acid (S)-2-(3,4-dichloro-phenyl)-4-(spiro[1-benzothiophene-3,4'-piperidinyl])butyl ester
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C29H29Cl2NO3S
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1
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| 1 |
IC50 = 4 nM
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CP0383532
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benzyl N-[1-[[(3S,4S)-1-(cyclohexanecarbonyl)-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-ethylcarbamate
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C33H45N3O3
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1
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| 1 |
IC50 = 4 nM
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CP0438099
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benzyl N-ethyl-N-[1-[[(3S,4S)-1-(naphthalene-1-carbonyl)-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]carbamate
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C37H41N3O3
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1
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| 1 |
IC50 = 4 nM
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CP0654010
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Ethyl-(1-{4-[(R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-imidazolidin-1-yl]-3-methyl-3-phenyl-butyl}-piperidin-4-yl)-carbamic acid benzyl ester
Show/Hide
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C38H45N5O4
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1
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| 1 |
IC50 = 4 nM
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CP0182315
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Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-piperidin-4-yl]-carbamic acid 4-nitro-benzyl ester
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C33H37N5O4
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1
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| 1 |
IC50 = 4 nM
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CP0263077
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(2-methylphenyl)methyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-propylcarbamate
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C34H45N3O4S
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1
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| 1 |
IC50 = 4 nM
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CP0347318
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1-[1-[4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-3-phenyl-1-propylurea
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C32H42N4O3S
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1
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| 1 |
IC50 = 4 nM
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CP0377832
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benzyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-(3-chlorophenyl)butyl]piperidin-4-yl]-N-propylcarbamate
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C33H42ClN3O4S
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1
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| 1 |
IC50 = 4 nM
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CP0458822
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N-[1-[(3R)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-2-phenoxy-N-propylacetamide
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C33H43N3O4S
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1
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| 1 |
IC50 = 4 nM
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CP0398591
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CHEMBL524050
Show/Hide
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C32H43N5O
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1
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| 1 |
IC50 = 4 nM
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CP0526793
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2-(4-fluorophenyl)-2-(4-(3-fluorophenyl)-4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)piperidin-1-yl)acetic acid
Show/Hide
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C36H40F2N4O2
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1
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| 1 |
IC50 = 4 nM
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CP0204173
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(S)-5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4-methylpiperidin-4-yl)-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
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C31H49N5O4
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2
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| 1 |
IC50 = 4 nM
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| 2 |
IC50 = 25 nM
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CP0242683
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N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)-N-prop-2-enylacetamide
Show/Hide
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C34H45N3O5S
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1
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| 1 |
IC50 = 4 nM
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CP0424819
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N-(3,4-dichlorophenyl)-N-[3-[4-[(4-fluorophenyl)sulfonylamino]piperidin-1-yl]propyl]-1-methylsulfonylpiperidine-4-carboxamide
Show/Hide
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C27H35Cl2FN4O5S2
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1
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| 1 |
IC50 = 4.6 nM
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CP0435459
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methyl 4-[[1-[3-(3,4-dichloro-N-(1-methylsulfonylpiperidine-4-carbonyl)anilino)propyl]piperidin-4-yl]methyl]benzoate
Show/Hide
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C30H39Cl2N3O5S
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1
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| 1 |
IC50 = 4.6 nM
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CP0871026
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(S)-(-)-9-{4-[2-(butoxy)ethoxy]phenyl}-1-propyl-N-(4-{[(1-propyl-1H-imidazol-5-yl)methyl]sulfinyl}phenyl)-2,3,4,5-tetrahydro-1H-1-benzazonine-6-carboxamide
Show/Hide
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C41H52N4O4S
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1
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| 1 |
IC50 = 4.7 nM
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CP0460270
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(2R)-3-cyclopropyl-2-((3S,4S)-3-(3-fluorophenyl)-4-((4-(3-(4-fluorophenyl)-4-hydroxybutyl)piperidin-1-yl)methyl)pyrrolidin-1-yl)propanoic acid
Show/Hide
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C32H42F2N2O3
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1
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| 1 |
IC50 = 4.8 nM
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CP0391500
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benzyl N-[1-[[(3S,4S)-1-benzoyl-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-ethylcarbamate
Show/Hide
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C33H39N3O3
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1
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| 1 |
IC50 = 5 nM
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CP0653196
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Allyl-(1-{4-[(R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-imidazolidin-1-yl]-3-methyl-3-phenyl-butyl}-piperidin-4-yl)-carbamic acid benzyl ester
Show/Hide
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C39H45N5O4
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1
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| 1 |
IC50 = 5 nM
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CP0122557
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1'-[3-(3-chlorophenyl)-4-methyl(phenyl)sulfonamido-(3S)-butyl]-3-oxospiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]
Show/Hide
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C30H33ClN2O3S
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1
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| 1 |
IC50 = 5 nM
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CP0316019
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N-[(2S)-2-(3-chlorophenyl)-4-[4-(3-phenylpropyl)piperidin-1-yl]butyl]-N-methylbenzenesulfonamide
Show/Hide
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C31H39ClN2O2S
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1
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| 1 |
IC50 = 5 nM
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CP0465981
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benzyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-methylcarbamate
Show/Hide
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C31H39N3O4S
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1
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| 1 |
IC50 = 5 nM
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CP0476648
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benzyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-butylcarbamate
Show/Hide
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C34H45N3O4S
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1
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| 1 |
IC50 = 5 nM
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CP0465357
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(4-{3-[1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmethyl)-4-hydroxy-piperidin-4-yl]-propyl}-phenyl)-acetic acid
Show/Hide
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C34H48N2O3
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1
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| 1 |
IC50 = 5 nM
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CP0503253
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(2S,3aS,4S,5S)-2,4-Diphenyl-5-[4-(3-phenyl-propyl)-piperidin-1-ylmethyl]-hexahydro-pyrrolo[1,2-b]isoxazole
Show/Hide
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C33H40N2O
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1
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| 1 |
IC50 = 5 nM
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CP0543258
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1-benzyloxycarbonyl(ethyl)1-[4'-phenyl-(3a'S,4'S,5'S)-spiro[cyclohexane-1,2'-perhydropyrrolo[1,2-b]isoxazole]-5-ylmethyl]hexahydro-4-pyridinylamine
Show/Hide
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C33H45N3O3
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1
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| 1 |
IC50 = 5 nM
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CP0408886
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(R)-2-cyclohexyl-2-((3S,4S)-3-phenyl-4-((4-(propyl(pyridin-3-yl)amino)piperidin-1-yl)methyl)pyrrolidin-1-yl)acetic acid
Show/Hide
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C32H46N4O2
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1
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| 1 |
IC50 = 5 nM
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CP0042193
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(S)-2-cyclohexyl-2-((3S,4S)-3-((4-hydroxy-4-(3-phenylpropyl)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)acetic acid
Show/Hide
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C33H46N2O3
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1
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| 1 |
IC50 = 5 nM
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CP0527663
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(R)-2-[(2S,3S)-3-{4-[5-(2,4-Difluoro-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
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C33H41F3N4O2
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1
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| 1 |
IC50 = 5 nM
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CP0386290
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(E)-N-((4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)-4-phenylpiperidin-1-yl)(morpholino)methylene)cyanamide
Show/Hide
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C34H43N7O
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1
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| 1 |
IC50 = 5 nM
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CP0398593
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2-(2,6-dimethylphenyl)-2-(4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)-4-phenylpiperidin-1-yl)acetic acid
Show/Hide
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C38H46N4O2
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1
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| 1 |
IC50 = 5 nM
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CP0528318
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methyl 2-[4-[2-[(1R,5S)-3-(2-methylbenzimidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl]ethyl]-4-phenylpiperidin-1-yl]-2-phenylacetate
Show/Hide
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C37H44N4O2
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1
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| 1 |
IC50 = 5 nM
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CP0382894
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N-[(1S)-3-[(1S,5R)-3-(3,5-dimethyl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-(3-fluorophenyl)propyl]-4,4-difluorocyclohexane-1-carboxamide
Show/Hide
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C27H36F3N5O
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1
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| 1 |
IC50 = 5 nM
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CP0447372
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N-[(1S)-3-[(1S,5R)-3-(3,5-dimethyl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-(3-fluorophenyl)propyl]-3,3-difluorocyclobutane-1-carboxamide
Show/Hide
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C25H32F3N5O
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1
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| 1 |
IC50 = 5 nM
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CP0035124
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4-((3-allyl-3-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-yl)ureido)methyl)-N,N-dimethylbenzenesulfonamide
Show/Hide
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C35H49N5O5S
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1
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| 1 |
IC50 = 5 nM
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CP0399231
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N-ethyl-N-[1-[(3R)-3-(3-methoxyphenyl)-3-(1-methylsulfonylpiperidin-4-yl)propyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C32H47N3O6S2
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1
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| 1 |
IC50 = 5 nM
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CP0400751
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N-ethyl-2-(4-methylsulfonylphenyl)-N-[1-[3-phenyl-3-(4-phenylpiperazin-1-yl)propyl]piperidin-4-yl]acetamide
Show/Hide
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C35H46N4O3S
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1
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| 1 |
IC50 = 5 nM
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CP0939145
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endo-tert-Butyl endo-4-(3-chlorophenyl)-4-{2-[3-(2-methyl-1H-benzimidazol-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]ethyl}piperidine-1-carboxylate
Show/Hide
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C33H43ClN4O2
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1
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| 1 |
IC50 = 5.012 nM
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CP0036979
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(2,4-dimethyl-1-oxy-pyridin-3-yl)-[4'-methyl-4-(phenyl-pyridin-3-yl-amino)-[1,4']bipiperidinyl-1'-yl]-methanone
Show/Hide
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C30H37N5O2
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2
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| 1 |
IC50 = 5.1 nM
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| 2 |
IC50 = 43.6 nM
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CP0503096
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N-(3,4-dichlorophenyl)-N-[3-[4-[[4-(methylcarbamoyl)phenyl]methyl]piperidin-1-yl]propyl]-1-methylsulfonylpiperidine-4-carboxamide
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C30H40Cl2N4O4S
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1
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| 1 |
IC50 = 5.1 nM
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CP0922298
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endo-(4-(3-Chloro-phenyl)-4-{2-[3-(2-methyl-benzoimidazol-1-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}-piperidin-1-yl)-phenyl-methanone
Show/Hide
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C35H39ClN4O
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1
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| 1 |
IC50 = 5.248 nM
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CP0394989
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N-methyl-N-[(2S)-2-methyl-4-[1-[(4-nitrophenyl)methyl]-2-oxo-4,4a,5,7,8,8a-hexahydro-3H-1,6-naphthyridin-6-yl]-2-phenylbutyl]benzenesulfonamide
Show/Hide
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C33H40N4O5S
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1
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| 1 |
IC50 = 5.3 nM
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CP0242685
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N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-2-(4-nitrophenyl)-N-prop-2-enylacetamide
Show/Hide
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C33H42N4O5
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1
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| 1 |
IC50 = 5.3 nM
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CP0496146
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N-ethyl-2-(4-methylsulfonylphenyl)-N-[1-[3-phenyl-3-[1-(2,2,2-trifluoroethylsulfonyl)piperidin-4-yl]propyl]piperidin-4-yl]acetamide
Show/Hide
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C32H44F3N3O5S2
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1
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| 1 |
IC50 = 5.4 nM
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CP0460302
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2-[3-[4-(5-Benzyl-2-ethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-2,3-dimethyl-butyric acid
Show/Hide
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C34H45FN4O2
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1
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| 1 |
IC50 = 5.5 nM
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CP0780616
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4-(4-(((R)-1-butyl-3-((R)-cyclohexyl(hydroxy)methyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl)methyl)phenoxy)benzoic acid hydrochloride
Show/Hide
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C33H44ClN3O6
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2
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| 1 |
IC50 = 5.8 nM
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| 2 |
IC50 = 34 nM
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CP0436202
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N-[4-[3-[4-[ethyl-[2-(4-methylsulfonylphenyl)acetyl]amino]piperidin-1-yl]-1-phenylpropyl]phenyl]-2-phenylacetamide
Show/Hide
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C39H45N3O4S
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1
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| 1 |
IC50 = 5.9 nM
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CP0531452
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6-chloro-2,4-dimethyl-N-[3-[4-[(5R)-2-oxo-5-phenyl-3-(pyridin-2-ylmethyl)imidazolidin-1-yl]piperidin-1-yl]butyl]pyridine-3-carboxamide
Show/Hide
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C32H39ClN6O2
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1
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| 1 |
IC50 = 5.9 nM
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CP0186835
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methyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-(cyclohexylmethyl)carbamate
Show/Hide
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C31H45N3O4S
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1
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| 1 |
IC50 = 6 nM
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CP0511109
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[4-(trifluoromethyl)phenyl]methyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-propylcarbamate
Show/Hide
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C34H42F3N3O4S
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1
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| 1 |
IC50 = 6 nM
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CP0555214
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1-[1-[4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-3-[(1R)-1-phenylethyl]-1-propylurea
Show/Hide
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C34H46N4O3S
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1
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| 1 |
IC50 = 6 nM
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CP0486731
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(3-{3-[1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmethyl)-4-hydroxy-piperidin-4-yl]-propyl}-phenyl)-acetic acid
Show/Hide
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C34H48N2O3
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1
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| 1 |
IC50 = 6 nM
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CP0449908
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1-(((3S,4S)-1-(cyclohexylmethyl)-4-phenylpyrrolidin-3-yl)methyl)-4-(3-(pyridin-3-yl)propyl)piperidin-4-ol
Show/Hide
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C31H45N3O
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1
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| 1 |
IC50 = 6 nM
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CP0509874
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Allyl-[1-((2S,3aS,4S,5S)-2,5-diphenyl-hexahydro-pyrrolo[1,2-b]isoxazol-4-ylmethyl)-piperidin-4-yl]-carbamic acid 4-nitro-benzyl ester
Show/Hide
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C35H40N4O5
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1
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| 1 |
IC50 = 6 nM
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CP0391341
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cyclohexyl-[(3S,4S)-3-phenyl-4-[[4-[prop-2-enyl(pyridin-2-yl)amino]piperidin-1-yl]methyl]pyrrolidin-1-yl]methanone
Show/Hide
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C31H42N4O
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1
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| 1 |
IC50 = 6 nM
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CP0431348
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N-cyclohexyl-4-[2-[(1R,5S)-3-(2-methylbenzimidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl]ethyl]-4-phenylpiperidine-1-carboxamide
Show/Hide
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C35H47N5O
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1
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| 1 |
IC50 = 6 nM
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CP0496152
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N-[(1S)-3-[(3aS,6aR)-5-(3,5-dimethyl-1,2,4-triazol-4-yl)-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-1-(3-fluorophenyl)propyl]-3,3-difluorocyclobutane-1-carboxamide
Show/Hide
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C25H32F3N5O
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1
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| 1 |
IC50 = 6 nM
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CP0522014
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N-[(1S)-3-[(3aS,6aR)-5-(3,5-dimethyl-1,2,4-triazol-4-yl)-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-1-(3-fluorophenyl)propyl]-3,3-difluorocyclobutane-1-carboxamide
Show/Hide
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C25H32F3N5O
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1
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| 1 |
IC50 = 6 nM
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CP0657856
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(+/-)-1-butyl-3-(cyclohexylmethyl)-9-(4-phenoxybenzyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C32H44ClN3O3
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3
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| 1 |
IC50 = 6.1 nM
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| 2 |
IC50 = 28 nM
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| 3 |
IC50 = 170 nM
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CP0066240
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4-(trifluoromethoxy)benzyl allyl(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-yl)carbamate
Show/Hide
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C34H42F3N3O5
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1
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| 1 |
IC50 = 6.15 nM
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CP0297707
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1-allyl-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-yl)-3-(4-(trifluoromethoxy)benzyl)urea
Show/Hide
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C34H43F3N4O4
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1
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| 1 |
IC50 = 6.15 nM
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CP0400740
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4-methoxybenzyl allyl(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-yl)carbamate
Show/Hide
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C34H45N3O5
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1
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| 1 |
IC50 = 6.22 nM
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CP0485448
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(R)-[(3S,4S)-3-(4-Benzoimidazol-1-ylmethyl-piperidin-1-ylmethyl)-4-phenyl-pyrrolidin-1-yl]-cyclohexyl-acetic acid
Show/Hide
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C32H42N4O2
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1
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| 1 |
IC50 = 6.3 nM
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CP0503888
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N-ethyl-N-[1-[3-(4-methoxyphenyl)-3-phenylpropyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C32H40N2O4S
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1
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| 1 |
IC50 = 6.3 nM
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CP0492018
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N-methyl-N-[(2S)-2-methyl-2-phenyl-4-[1-(2-phenylacetyl)-3,3a,4,6,7,7a-hexahydro-2H-pyrrolo[3,2-c]pyridin-5-yl]butyl]benzenesulfonamide
Show/Hide
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C33H41N3O3S
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1
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| 1 |
IC50 = 6.4 nM
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CP0403867
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6-chloro-2,4-dimethyl-N-[3-[4-[(5R)-2-oxo-5-phenyl-3-propylimidazolidin-1-yl]piperidin-1-yl]butyl]pyridine-3-carboxamide
Show/Hide
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C29H40ClN5O2
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1
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| 1 |
IC50 = 6.4 nM
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CP0433168
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(4-methyl-4-(4-(phenyl(pyridin-3-yl)amino)piperidin-1-yl)piperidin-1-yl)(3-methylpyridin-2-yl)methanone
Show/Hide
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C29H35N5O
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1
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| 1 |
IC50 = 6.5 nM
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CP0403892
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(R)-2-cyclohexyl-2-((3S,4S)-3-phenyl-4-((4-(propyl(pyrimidin-2-yl)amino)piperidin-1-yl)methyl)pyrrolidin-1-yl)acetic acid
Show/Hide
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C31H45N5O2
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1
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| 1 |
IC50 = 6.6 nM
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CP0413858
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4-[5-[[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]pyridin-2-yl]oxybenzoic acid
Show/Hide
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C32H36N4O5
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1
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| 1 |
IC50 = 6.6 nM
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CP0463239
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1-acetyl-N-(3-chloro-4-methylphenyl)-N-[3-[4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]propyl]piperidine-4-carboxamide
Show/Hide
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C30H40ClFN4O2
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1
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| 1 |
IC50 = 6.6 nM
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CP0040937
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1-allyl-1-((1R,3S,5S)-8-(((3S,4R)-1-(cyclopentanecarbonyl)-4-(3-fluorophenyl)-4-hydroxypyrrolidin-3-yl)methyl)-8-azabicyclo[3.2.1]octan-3-yl)-3-(4-(trifluoromethyl)benzyl)urea
Show/Hide
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C36H44F4N4O3
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1
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| 1 |
IC50 = 6.77 nM
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CP0849520
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(S)-(-)-9-{4-[2-(butoxy)ethoxy]phenyl}-1-isobutyl-N-(4-{[(1-propyl-1H-imidazol-5-yl)methyl]sulfinyl}phenyl)-2,3,4,5-tetrahydro-1H-1-benzazonine-6-carboxamide
Show/Hide
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C42H54N4O4S
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1
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| 1 |
IC50 = 6.8 nM
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CP0670713
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Allyl-(1-{4-[(R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-imidazolidin-1-yl]-3-phenyl-butyl}-piperidin-4-yl)-carbamic acid benzyl ester
Show/Hide
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C38H43N5O4
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1
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| 1 |
IC50 = 7 nM
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CP0387906
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1-(((3S,4S)-1-(cyclohexylmethyl)-4-phenylpyrrolidin-3-yl)methyl)-4-(3-(pyridin-2-yl)propyl)piperidin-4-ol
Show/Hide
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C31H45N3O
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1
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| 1 |
IC50 = 7 nM
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CP0502497
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(2R)-3-cyclobutyl-2-[(3S,4S)-3-[[4-(5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)piperidin-1-yl]methyl]-4-(3-fluorophenyl)pyrrolidin-1-yl]propanoic acid
Show/Hide
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C31H40FN5O2
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1
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| 1 |
IC50 = 7 nM
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CP0474270
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2-(4-methoxyphenyl)-2-(4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)-4-phenylpiperidin-1-yl)acetic acid
Show/Hide
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C37H44N4O3
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1
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| 1 |
IC50 = 7 nM
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CP0474272
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2-(benzo[d][1,3]dioxol-5-yl)-2-(4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)-4-phenylpiperidin-1-yl)acetic acid
Show/Hide
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C37H42N4O4
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1
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| 1 |
IC50 = 7 nM
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CP0500743
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(E)-cyclopentyl N-cyano-4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)-4-phenylpiperidine-1-carbimidate
Show/Hide
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C35H44N6O
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1
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| 1 |
IC50 = 7 nM
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CP0514670
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N-tert-butyl-4-[2-[(1R,5S)-3-(2-methylbenzimidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl]ethyl]-4-phenylpiperidine-1-carboxamide
Show/Hide
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C33H45N5O
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1
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| 1 |
IC50 = 7 nM
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CP0537784
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4-butyl-3-(cyclohexylmethyl)-8-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4-methylpiperidin-4-yl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Show/Hide
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C31H49N5O3
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1
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| 1 |
IC50 = 7 nM
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CP0502567
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N-[(1S)-3-[(1S,5R)-3-(3,5-dimethyl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-(3-fluorophenyl)propyl]oxolane-3-carboxamide
Show/Hide
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C25H34FN5O2
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1
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| 1 |
IC50 = 7 nM
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CP0484605
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1-acetyl-N-(3-chlorophenyl)-N-[3-[4-[ethyl-(2-phenylacetyl)amino]piperidin-1-yl]propyl]piperidine-4-carboxamide
Show/Hide
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C32H43ClN4O3
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2
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| 1 |
IC50 = 7 nM
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| 2 |
IC50 = 251.67 nM
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CP0436180
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4-[3-(4-{Ethyl-[2-(4-methanesulfonyl-phenyl)-acetyl]-amino}-piperidin-1-yl)-1-phenyl-propyl]-benzoic acid methyl ester
Show/Hide
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C33H40N2O5S
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1
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| 1 |
IC50 = 7.1 nM
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CP0896075
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endo-1-(8-{2-[4-(3,4-Dichlorophenyl)-1-(2,2-dimethylpropanoyl)-4-piperidinyl]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-2-methyl-1H-benzimidazole
Show/Hide
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C33H42Cl2N4O
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1
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| 1 |
IC50 = 7.244 nM
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CP0502566
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N-[1-[3-(4-acetamidophenyl)-3-(3-fluorophenyl)propyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C33H40FN3O4S
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1
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| 1 |
IC50 = 7.9 nM
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CP0448035
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(2,6-Dichloro-phenyl)-(4-diphenylamino-4'-methyl-[1,4']bipiperidinyl-1'-yl)-methanone
Show/Hide
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C30H33Cl2N3O
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1
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| 1 |
IC50 = 7.9 nM
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CP0508889
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1-phenyl-3-{1-[4'-phenyl-(3a'S,4'S,5'S)-spiro[cyclohexane-1,2'-perhydropyrrolo[1,2-b]isoxazole]-5-ylmethyl]hexahydro-4-pyridinyl}propane
Show/Hide
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C32H44N2O
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1
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| 1 |
IC50 = 8 nM
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CP0500744
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2-(4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)-4-phenylpiperidin-1-yl)-2-phenylacetic acid
Show/Hide
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C36H42N4O2
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1
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| 1 |
IC50 = 8 nM
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CP0463747
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N-[(1S)-3-[(3aS,6aR)-5-(3,5-dimethyl-1,2,4-triazol-4-yl)-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-1-(3-fluorophenyl)propyl]-4,4-difluorocyclohexane-1-carboxamide
Show/Hide
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C27H36F3N5O
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1
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| 1 |
IC50 = 8 nM
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CP0439882
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(R)-[(3S,4S)-3-(4-Benzotriazol-1-yl-piperidin-1-ylmethyl)-4-phenyl-pyrrolidin-1-yl]-cyclohexyl-acetic acid
Show/Hide
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C30H39N5O2
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1
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| 1 |
IC50 = 8.2 nM
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CP0720738
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(+/-)-1-butyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C29H40ClN3O3
|
3
|
| 1 |
IC50 = 8.3 nM
|
|
|
| 2 |
IC50 = 94 nM
|
|
|
| 3 |
IC50 = 120 nM
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CP0510359
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1-acetyl-N-(3-chloro-4-methylphenyl)-N-[3-[4-[(4-cyanophenyl)methyl]-2-methylpiperazin-1-yl]propyl]piperidine-4-carboxamide
Show/Hide
|
C31H40ClN5O2
|
1
|
| 1 |
IC50 = 8.3 nM
|
|
|
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CP0404847
|
N-[1-[3-(4-chlorophenyl)-3-phenylpropyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C31H37ClN2O3S
|
1
|
| 1 |
IC50 = 8.5 nM
|
|
|
|
CP0413843
|
6-chloro-2,4-dimethyl-N-[3-[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]butyl]pyridine-3-carboxamide
Show/Hide
|
C31H42ClN5O3
|
1
|
| 1 |
IC50 = 8.6 nM
|
|
|
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CP0520983
|
benzyl N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-prop-2-enylcarbamate
Show/Hide
|
C33H43N3O4
|
1
|
| 1 |
IC50 = 8.75 nM
|
|
|
|
CP0378681
|
1-acetyl-N-(3-chloro-4-methylphenyl)-N-[3-[(1S,4S)-5-[(4-fluorophenyl)methyl]-2,5-diazabicyclo[2.2.1]heptan-2-yl]propyl]piperidine-4-carboxamide
Show/Hide
|
C30H38ClFN4O2
|
1
|
| 1 |
IC50 = 8.8 nM
|
|
|
|
CP0516448
|
4-nitrobenzyl allyl(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-(3-fluorophenyl)-4-hydroxypyrrolidin-3-yl)methyl)piperidin-4-yl)carbamate
Show/Hide
|
C33H41FN4O6
|
1
|
| 1 |
IC50 = 8.85 nM
|
|
|
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CP0435458
|
N-[3-[4-[(4-carbamoylphenyl)methyl]piperidin-1-yl]propyl]-N-(3,4-dichlorophenyl)-1-methylsulfonylpiperidine-4-carboxamide
Show/Hide
|
C29H38Cl2N4O4S
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
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CP0431305
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N-ethyl-2-(4-methylsulfonylphenyl)-N-[1-[(3S)-3-phenyl-3-[4-(2,2,2-trifluoroethylsulfonyl)piperazin-1-yl]propyl]piperidin-4-yl]acetamide
Show/Hide
|
C31H43F3N4O5S2
|
1
|
| 1 |
IC50 = 8.9 nM
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|
|
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CP0504071
|
N-[1-[3-(1-benzylpiperidin-4-yl)-3-phenylpropyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C37H49N3O3S
|
1
|
| 1 |
IC50 = 8.9 nM
|
|
|
|
CP0467801
|
benzyl N-[1-[[(3S,4S)-1-benzyl-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-ethylcarbamate
Show/Hide
|
C33H41N3O2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0453521
|
cyclohexyl-[(3S,4S)-3-[[4-[cyclopropylmethyl(pyridin-2-yl)amino]piperidin-1-yl]methyl]-4-phenylpyrrolidin-1-yl]methanone
Show/Hide
|
C32H44N4O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0493787
|
((3S,4S)-3-phenyl-4-((4-(propyl(pyridin-2-yl)amino)piperidin-1-yl)methyl)pyrrolidin-1-yl)(pyrrolidin-1-yl)methanone
Show/Hide
|
C29H41N5O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0541749
|
5-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-methyl-3-phenyl-butyl]-octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid benzyl ester
Show/Hide
|
C33H41N3O4S
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0428056
|
N-ethyl-N-[1-[3-(3-fluorophenyl)-3-[4-(methanesulfonamido)phenyl]propyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C32H40FN3O5S2
|
1
|
| 1 |
IC50 = 9.1 nM
|
|
|
|
CP0409023
|
6-chloro-2,4-dimethyl-N-[3-[4-[(5R)-2-oxo-5-phenyl-3-(pyridin-3-ylmethyl)imidazolidin-1-yl]piperidin-1-yl]butyl]pyridine-3-carboxamide
Show/Hide
|
C32H39ClN6O2
|
1
|
| 1 |
IC50 = 9.3 nM
|
|
|
|
CP0037285
|
(2S)-2-(3-chlorophenyl)-1-[(N-methyl-N-phenylsulfonyl)amino]-4-[spiro(2,3-dihydrobenzthiophene-3,40-piperidin-10-yl)]butane S-oxide
Show/Hide
|
C29H33ClN2O3S2
|
2
|
| 1 |
IC50 = 10 nM
|
|
|
| 2 |
IC50 = 35 nM
|
|
|
|
CP0167225
|
Allyl-[1-(4-benzoimidazol-1-yl-3-methyl-3-phenyl-butyl)-piperidin-4-yl]-carbamic acid 4-nitro-benzyl ester
Show/Hide
|
C34H39N5O4
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0186836
|
methyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-hexylcarbamate
Show/Hide
|
C30H45N3O4S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0449078
|
phenyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-ethylcarbamate
Show/Hide
|
C31H39N3O4S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0464431
|
4-(3-(1-(((3S,4S)-1-(cyclohexylmethyl)-4-phenylpyrrolidin-3-yl)methyl)-4-hydroxypiperidin-4-yl)propyl)benzoic acid
Show/Hide
|
C33H46N2O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0399795
|
cyclobutyl-[(3S,4S)-3-phenyl-4-[[4-[propyl(pyridin-2-yl)amino]piperidin-1-yl]methyl]pyrrolidin-1-yl]methanone
Show/Hide
|
C29H40N4O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0377357
|
N-[(2S)-4-(1-benzyl-2-oxo-4,4a,5,7,8,8a-hexahydro-3H-1,6-naphthyridin-6-yl)-2-methyl-2-phenylbutyl]-N-methylbenzenesulfonamide
Show/Hide
|
C33H41N3O3S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0502818
|
(R)-Cyclohexyl-{(3S,4S)-3-[4-(1H-indol-3-yl)-piperidin-1-ylmethyl]-4-phenyl-pyrrolidin-1-yl}-acetic acid
Show/Hide
|
C32H41N3O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0216128
|
2-(4-Dimethylsulfamoyl-phenyl)-N-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-N-ethyl-acetamide
Show/Hide
|
C32H41N3O3S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0507123
|
4-butyl-3-(cyclohexylmethyl)-8-(1-(2,6-dimethylbenzoyl)-4-methylpiperidin-4-yl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Show/Hide
|
C33H51N3O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0538553
|
(5S)-5-butyl-9-(1-(2,4-dimethylnicotinoyl)-4-methylpiperidin-4-yl)-3-((tetrahydro-2H-pyran-2-yl)methyl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
|
C32H50N4O4
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0390755
|
N-[3-[4-[5-(3-bromophenyl)-3-cyclohexyl-2-oxoimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
|
C31H43BrN6O2
|
1
|
| 1 |
IC50 = 10.4 nM
|
|
|
|
CP0504454
|
1-acetyl-N-(3-chloro-4-methylphenyl)-N-[3-[4-(4-fluorophenyl)sulfonyl-2-methylpiperazin-1-yl]propyl]piperidine-4-carboxamide
Show/Hide
|
C29H38ClFN4O4S
|
1
|
| 1 |
IC50 = 10.9 nM
|
|
|
|
CP0373713
|
(2S,3aS,4S,5S)-2,5-Diphenyl-4-[4-(3-phenyl-propyl)-piperidin-1-ylmethyl]-hexahydro-pyrrolo[1,2-b]isoxazole
Show/Hide
|
C33H40N2O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0502548
|
5-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-methyl-3-phenyl-butyl]-octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester
Show/Hide
|
C30H43N3O4S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0372686
|
N-[1-[3-[4-(benzylsulfonylamino)phenyl]-3-phenylpropyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C38H45N3O5S2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0886306
|
(S)-1-butyl-3-isobutyl-9-(4-phenoxy-benzyl)-1,4,9-triaza-spiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
|
C29H40ClN3O3
|
2
|
| 1 |
IC50 = 11 nM
|
|
|
| 2 |
IC50 = 84 nM
|
|
|
|
CP0435456
|
N-[3-[4-[[4-(tert-butylcarbamoyl)phenyl]methyl]piperidin-1-yl]propyl]-N-(3,4-dichlorophenyl)-1-methylsulfonylpiperidine-4-carboxamide
Show/Hide
|
C33H46Cl2N4O4S
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0467610
|
(Z)-N'-cyano-N-methyl-4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)-4-phenylpiperidine-1-carboximidamide
Show/Hide
|
C31H39N7
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0066241
|
N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-2-(4-fluorophenyl)-N-prop-2-enylacetamide
Show/Hide
|
C33H42FN3O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0514468
|
N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-(4-fluorophenyl)-4-hydroxypyrrolidin-3-yl]methyl]piperidin-4-yl]-2-[4-(methylsulfamoyl)phenyl]-N-prop-2-enylacetamide
Show/Hide
|
C34H45FN4O5S
|
1
|
| 1 |
IC50 = 11.17 nM
|
|
|
|
CP0395775
|
6-chloro-2,4-dimethyl-N-[3-[4-[(5R)-2-oxo-5-phenyl-3-propan-2-ylimidazolidin-1-yl]piperidin-1-yl]butyl]pyridine-3-carboxamide
Show/Hide
|
C29H40ClN5O2
|
1
|
| 1 |
IC50 = 11.2 nM
|
|
|
|
CP0125375
|
4-((3-allyl-3-((1R,3S,5S)-8-(((3S,4R)-1-(cyclopentanecarbonyl)-4-(3-fluorophenyl)-4-hydroxypyrrolidin-3-yl)methyl)-8-azabicyclo[3.2.1]octan-3-yl)ureido)methyl)-N,N-dimethylbenzenesulfonamide
Show/Hide
|
C37H50FN5O5S
|
1
|
| 1 |
IC50 = 11.4 nM
|
|
|
|
CP0390753
|
N-[3-[4-[3-cyclohexyl-5-(3-methylphenyl)-2-oxoimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
|
C32H46N6O2
|
1
|
| 1 |
IC50 = 11.7 nM
|
|
|
|
CP0504455
|
1-acetyl-N-(3-chloro-4-methylphenyl)-N-[3-[4-[(3-fluorophenyl)methyl]-2-methylpiperazin-1-yl]propyl]piperidine-4-carboxamide
Show/Hide
|
C30H40ClFN4O2
|
1
|
| 1 |
IC50 = 11.7 nM
|
|
|
|
CP0531458
|
methyl N-[1-[[(3S,4S)-1-(2-chlorobenzoyl)-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-(cyclopentylmethyl)carbamate
Show/Hide
|
C31H40ClN3O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0495018
|
1-(1-Cyclohexylmethyl-4-phenyl-pyrrolidin-3-ylmethyl)-4-(3-pyridin-4-yl-propyl)-piperidin-4-ol
Show/Hide
|
C31H45N3O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0406273
|
cyclohexyl-[(3S,4S)-3-phenyl-4-[[4-[propyl(pyridin-2-yl)amino]piperidin-1-yl]methyl]pyrrolidin-1-yl]methanone
Show/Hide
|
C31H44N4O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0408961
|
((3S,4S)-3-((4-(allyl(pyrimidin-2-yl)amino)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)(cyclohexyl)methanone
Show/Hide
|
C30H41N5O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0486013
|
(R)-3-Cyclobutyl-2-[(3S,4S)-3-phenyl-4-(4-[1,2,4]triazolo[4,3-a]pyridin-3-yl-piperidin-1-ylmethyl)-pyrrolidin-1-yl]-propionic acid
Show/Hide
|
C29H37N5O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0502819
|
(R)-Cyclohexyl-{(3S,4S)-3-[4-(4-oxo-4H-quinazolin-3-yl)-piperidin-1-ylmethyl]-4-phenyl-pyrrolidin-1-yl}-acetic acid
Show/Hide
|
C32H40N4O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0502563
|
N-ethyl-N-[1-[3-(4-methylsulfanylphenyl)-3-phenylpropyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C32H40N2O3S2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0435457
|
N-[3-[4-[(2-carbamoylphenyl)methyl]piperidin-1-yl]propyl]-N-(3,4-dichlorophenyl)-1-methylsulfonylpiperidine-4-carboxamide
Show/Hide
|
C29H38Cl2N4O4S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0538552
|
(S)-5-butyl-9-(1-(4,6-dimethyl-2-oxo-2H-pyran-5-carbonyl)-4-methylpiperidin-4-yl)-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
|
C32H49N3O6
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0671912
|
Ethyl-(1-{4-[(R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-imidazolidin-1-yl]-3-phenyl-butyl}-piperidin-4-yl)-carbamic acid benzyl ester
Show/Hide
|
C37H43N5O4
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0439883
|
(R)-3-cyclobutyl-2-((3S,4S)-3-(3-fluorophenyl)-4-((4-(imidazo[1,5-a]pyridin-3-yl)piperidin-1-yl)methyl)pyrrolidin-1-yl)propanoic acid
Show/Hide
|
C30H37FN4O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0500796
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-2-(4-methylsulfonylphenyl)-N-prop-2-enylacetamide
Show/Hide
|
C32H38N2O3S
|
2
|
| 1 |
IC50 = 13 nM
|
|
|
| 2 |
IC50 = 37 nM
|
|
|
|
CP0921643
|
(S)-4-(3-(2-(1-butyl-3-(cyclohexylmethyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl)ethyl)phenoxy)benzoic acid hydrochloride
Show/Hide
|
C34H46ClN3O5
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0468399
|
(E)-isopropyl N-cyano-4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)-4-phenylpiperidine-1-carbimidothioate
Show/Hide
|
C33H42N6S
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0474268
|
2-((4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)-4-phenylpiperidin-1-yl)methyl)oxazole
Show/Hide
|
C32H39N5O
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0522783
|
methyl 2-(2,3-dimethylphenyl)-2-[4-[2-[(1R,5S)-3-(2-methylbenzimidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl]ethyl]-4-phenylpiperidin-1-yl]acetate
Show/Hide
|
C39H48N4O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0373701
|
N-[(1S)-3-[(1R,5S)-3-(3,5-dimethyl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-(3-fluorophenyl)propyl]oxane-4-carboxamide
Show/Hide
|
C26H36FN5O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0756560
|
(S)-4-(4-((1-butyl-3-(cyclohexylmethyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl)methyl)phenoxy)benzoic acid hydrochloride
Show/Hide
|
C33H44ClN3O5
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0390757
|
4-[4-[[4-[(5R)-3-cyclohexyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]phenoxy]benzoic acid
Show/Hide
|
C34H39N3O4
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0453435
|
(R)-2-[(2S,3S)-3-[4-(2-Ethyl-5-pyridin-3-ylmethyl-2H-pyrazol-3-yl)-piperidin-1-ylmethyl]-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-butyric acid
Show/Hide
|
C32H42FN5O2
|
1
|
| 1 |
IC50 = 13.1 nM
|
|
|
|
CP0441404
|
4-nitrobenzyl allyl(1-(((3a'S,4'S,5'S)-5'-phenyltetrahydro-3'H-spiro[cyclohexane-1,2'-pyrrolo[1,2-b]isoxazole]-4'-yl)methyl)piperidin-4-yl)carbamate
Show/Hide
|
C34H44N4O5
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0384014
|
(2-Chloro-phenyl)-{(3S,4S)-3-phenyl-4-[4-(propyl-pyridin-2-yl-amino)-piperidin-1-ylmethyl]-pyrrolidin-1-yl}-methanone
Show/Hide
|
C31H37ClN4O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0373909
|
(5S)-5-butyl-9-((3aR,6aS)-2-(4,6-dimethylpyrimidine-5-carbonyl)octahydrocyclopenta[c]pyrrol-5-yl)-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
|
C32H49N5O4
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0379629
|
N-[(3S)-3-[4-[(5R)-3-cyclohexyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
|
C31H44N6O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0308241
|
1-allyl-1-((1R,3R,5S)-8-(((3S,4R)-1-(cyclopentanecarbonyl)-4-(3-fluorophenyl)-4-hydroxypyrrolidin-3-yl)methyl)-8-azabicyclo[3.2.1]octan-3-yl)-3-(4-(trifluoromethyl)benzyl)urea
Show/Hide
|
C36H44F4N4O3
|
1
|
| 1 |
IC50 = 14.3 nM
|
|
|
|
CP0066239
|
N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-2-(4-methoxyphenyl)-N-prop-2-enylacetamide
Show/Hide
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C34H45N3O4
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1
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| 1 |
IC50 = 14.6 nM
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CP0438085
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methyl N-[1-[[(3S,4S)-1-(cyclopentanecarbonyl)-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-(cyclopentylmethyl)carbamate
Show/Hide
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C30H45N3O3
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1
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| 1 |
IC50 = 15 nM
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CP0395194
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Allyl-{1-[4-(4-cyanomethyl-imidazol-1-yl)-3-phenyl-butyl]-piperidin-4-yl}-carbamic acid 4-nitro-benzyl ester
Show/Hide
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C31H36N6O4
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1
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| 1 |
IC50 = 15 nM
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CP0449174
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Allyl-[1-(4-indazol-1-yl-3-phenyl-butyl)-piperidin-4-yl]-carbamic acid 4-nitro-benzyl ester
Show/Hide
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C33H37N5O4
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1
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| 1 |
IC50 = 15 nM
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CP0451303
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Allyl-{1-[4-(4-nitro-imidazol-1-yl)-3-phenyl-butyl]-piperidin-4-yl}-carbamic acid 4-nitro-benzyl ester
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C29H34N6O6
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1
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| 1 |
IC50 = 15 nM
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CP0225194
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1'-[3-(3-chlorophenyl)-4-methyl(phenyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1,1-dioxide-3,4'-(hexahydropyridine)]
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C29H33ClN2O4S2
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1
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| 1 |
IC50 = 15 nM
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CP0076426
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cyclohexylmethyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-ethylcarbamate
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C32H47N3O4S
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1
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| 1 |
IC50 = 15 nM
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CP0214537
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methyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-butylcarbamate
Show/Hide
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C28H41N3O4S
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1
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| 1 |
IC50 = 15 nM
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CP0504593
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5-((3aR,6aS)-5-((S)-5-butyl-2-oxo-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,9-diazaspiro[5.5]undecan-9-yl)octahydrocyclopenta[c]pyrrole-2-carbonyl)-4,6-dimethylpicolinonitrile
Show/Hide
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C34H49N5O4
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1
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| 1 |
IC50 = 15 nM
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CP0399224
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N-ethyl-N-[1-[3-(4-ethylsulfonylpiperazin-1-yl)-3-phenylpropyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C31H46N4O5S2
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1
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| 1 |
IC50 = 15 nM
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CP0378679
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1-acetyl-N-[3-(4-benzyl-2-methylpiperazin-1-yl)propyl]-N-(3-chloro-4-methylphenyl)piperidine-4-carboxamide
Show/Hide
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C30H41ClN4O2
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1
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| 1 |
IC50 = 15.1 nM
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CP0524201
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(2,4-Dimethyl-pyridin-3-yl)-(4-diphenylamino-[1,4']bipiperidinyl-1'-yl)-methanone
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C30H36N4O
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1
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| 1 |
IC50 = 15.5 nM
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CP0442610
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[4-[4-(N-benzyl-4-bromoanilino)piperidin-1-yl]-4-methylpiperidin-1-yl]-(2,6-dimethylphenyl)methanone
Show/Hide
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C33H40BrN3O
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1
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| 1 |
IC50 = 15.6 nM
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CP0403864
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4-[4-[[4-[(5R)-3-(oxan-4-yl)-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]phenoxy]benzoic acid
Show/Hide
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C33H37N3O5
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1
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| 1 |
IC50 = 15.7 nM
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CP0867013
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endo-1-(8-{2-[4-(3,4-Dichlorophenyl)-1-(phenylcarbonyl)-4-piperidinyl]ethyl}-8-azabicyclo[3.2.1]oct-3-yl)-2-methyl-1H-benzimidazole
Show/Hide
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C35H38Cl2N4O
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1
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| 1 |
IC50 = 15.85 nM
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CP0395219
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Allyl-{1-[4-(4,5-dichloro-imidazol-1-yl)-3-phenyl-butyl]-piperidin-4-yl}-carbamic acid 4-nitro-benzyl ester
Show/Hide
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C29H33Cl2N5O4
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1
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| 1 |
IC50 = 16 nM
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CP0324242
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(3-{4-[5-(4-Cyano-phenyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-phenyl-pyrrolidin-1-yl)-cyclohexyl-acetic acid
Show/Hide
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C36H45N5O2
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1
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| 1 |
IC50 = 16 nM
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CP0502547
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5-[(S)-4-(Benzenesulfonyl-methyl-amino)-3-phenyl-butyl]-octahydro-pyrrolo[3,2-c]pyridine-1-carboxylic acid tert-butyl ester
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C29H41N3O4S
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1
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| 1 |
IC50 = 16 nM
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CP0442044
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1-acetyl-N-(3-(4-benzylpiperidin-1-yl)propyl)-N-phenylpiperidine-4-carboxamide
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C29H39N3O2
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1
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| 1 |
IC50 = 16 nM
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CP0508681
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methyl N-[1-[[(3S,4S)-1-(cyclohexanecarbonyl)-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-(cyclopentylmethyl)carbamate
Show/Hide
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C31H47N3O3
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1
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| 1 |
IC50 = 17 nM
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CP0445033
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N-(3-chloro-4-methylphenyl)-N-[3-[4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]propyl]-1-methylsulfonylpiperidine-4-carboxamide
Show/Hide
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C29H40ClFN4O3S
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1
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| 1 |
IC50 = 17.1 nM
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CP0505844
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2-(4-bromophenyl)-N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-prop-2-enylacetamide
Show/Hide
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C33H42BrN3O3
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1
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| 1 |
IC50 = 17.8 nM
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CP0428054
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N-ethyl-N-[1-[3-[4-(methanesulfonamido)phenyl]-3-phenylpropyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C32H41N3O5S2
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2
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| 1 |
IC50 = 18 nM
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| 2 |
IC50 = 24 nM
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CP0430905
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N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C31H38N2O3S
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2
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| 1 |
IC50 = 18 nM
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| 2 |
IC50 = 76 nM
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CP0522781
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CHEMBL506788
Show/Hide
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C35H49N5O
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1
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| 1 |
IC50 = 18 nM
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CP0480176
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4-butyl-3-(cyclopentylmethyl)-8-(1-(2,6-dimethylbenzoyl)piperidin-4-yl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Show/Hide
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C31H47N3O3
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1
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| 1 |
IC50 = 18 nM
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CP0490975
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N-[(1S)-3-[(3aS,6aR)-5-(3,5-dimethyl-1,2,4-triazol-4-yl)-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-1-(3-fluorophenyl)propyl]oxolane-3-carboxamide
Show/Hide
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C25H34FN5O2
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1
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| 1 |
IC50 = 18 nM
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CP0379626
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N-[3-[4-[3-cyclohexyl-5-(3-fluoro-5-methylphenyl)-2-oxoimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
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C32H45FN6O2
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1
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| 1 |
IC50 = 18.5 nM
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CP0470393
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cyclopentyl-[(3S,4S)-3-phenyl-4-[(4-phenylpiperidin-1-yl)methyl]pyrrolidin-1-yl]methanone
Show/Hide
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C28H36N2O
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1
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| 1 |
IC50 = 19 nM
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CP0530542
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naphthalen-1-yl-[(3S,4S)-3-phenyl-4-[(4-phenylpiperidin-1-yl)methyl]pyrrolidin-1-yl]methanone
Show/Hide
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C33H34N2O
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1
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| 1 |
IC50 = 19 nM
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CP0405955
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3-Cyclopropyl-2-((S)-3-(3-fluoro-phenyl)-4-{4-[2-((R)-methoxy-phenyl-phosphinoyl)-ethyl]-piperidin-1-ylmethyl}-pyrrolidin-1-yl)-propionic acid
Show/Hide
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C31H42FN2O4P
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1
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| 1 |
IC50 = 19 nM
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CP0466974
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N-[1-[3-(4-chlorophenyl)-3-(3-fluorophenyl)propyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C31H36ClFN2O3S
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1
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| 1 |
IC50 = 19 nM
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CP0525141
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N-(3,4-dichlorophenyl)-N-[3-[4-[[4-(dimethylcarbamoyl)phenyl]methyl]piperidin-1-yl]propyl]-1-methylsulfonylpiperidine-4-carboxamide
Show/Hide
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C31H42Cl2N4O4S
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1
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| 1 |
IC50 = 19 nM
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CP0922299
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Cyclopentyl-(4-{2-[(1R,5R)-3-(2-methyl-benzoimidazol-1-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}-4-phenyl-piperidin-1-yl)-methanone
Show/Hide
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C34H44N4O
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1
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| 1 |
IC50 = 19.95 nM
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CP0076428
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methyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-propylcarbamate
Show/Hide
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C27H39N3O4S
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1
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| 1 |
IC50 = 20 nM
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CP0249042
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1-[1-[4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-3-benzyl-3-methyl-1-propylurea
Show/Hide
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C34H46N4O3S
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1
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| 1 |
IC50 = 20 nM
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CP0377786
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N-[1-[(3R)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-3-phenyl-N-propylpropanamide
Show/Hide
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C34H45N3O3S
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1
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| 1 |
IC50 = 20 nM
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CP0374999
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(R)-2-((3S,4S)-3-((4-(4-benzyl-1-ethyl-1H-pyrazol-3-yl)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)-2-cyclohexylacetic acid
Show/Hide
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C36H48N4O2
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1
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| 1 |
IC50 = 20 nM
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CP0522276
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(R)-N-(1-(3-(2,3-difluorophenyl)-3-(4-(methylsulfonyl)phenyl)propyl)piperidin-4-yl)-N-ethyl-2-(4-(methylsulfonyl)phenyl)acetamide
Show/Hide
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C32H38F2N2O5S2
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1
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| 1 |
IC50 = 20 nM
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CP0522277
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(R)-N-ethyl-2-(4-(methylsulfonyl)phenyl)-N-(1-(3-(4-(methylsulfonyl)phenyl)-3-(3-(trifluoromethyl)phenyl)propyl)piperidin-4-yl)acetamide
Show/Hide
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C33H39F3N2O5S2
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1
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| 1 |
IC50 = 20 nM
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CP0662064
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9-(1,4-benzodioxane-6-yl)-1-butyl-3-cyclohexyl-1,4,9-triazaspiro-[5.5]undeca-2,5-dione hydrochloride
Show/Hide
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C28H42ClN3O4
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2
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| 1 |
IC50 = 20 nM
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| 2 |
IC50 = 50 nM
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CP0424818
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1-acetyl-N-(3,4-dichlorophenyl)-N-{3-[4-(4-fluoroanilino)piperidin-1-yl]propyl}piperidine-4-carboxamide
Show/Hide
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C28H35Cl2FN4O2
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1
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| 1 |
IC50 = 20 nM
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CP0385549
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4-bromobenzyl allyl(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-yl)carbamate
Show/Hide
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C33H42BrN3O4
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1
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| 1 |
IC50 = 20.2 nM
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CP0444097
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((3S,4S)-3-{4-[Allyl-(5-trifluoromethyl-pyridin-2-yl)-amino]-piperidin-1-ylmethyl}-4-phenyl-pyrrolidin-1-yl)-cyclohexyl-methanone
Show/Hide
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C32H41F3N4O
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1
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| 1 |
IC50 = 21 nM
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CP0496765
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(R)-N-(1-(3-(3,4-difluorophenyl)-3-(4-(methylsulfonyl)phenyl)propyl)piperidin-4-yl)-N-ethyl-2-(4-(methylsulfonyl)phenyl)acetamide
Show/Hide
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C32H38F2N2O5S2
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1
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| 1 |
IC50 = 21 nM
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CP0462258
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N,N-dimethyl-4-[2-[(1R,5S)-3-(2-methylbenzimidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl]ethyl]-4-phenylpiperidine-1-carboxamide
Show/Hide
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C31H41N5O
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1
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| 1 |
IC50 = 21 nM
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CP0922771
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rac-1-Butyl-3-(cyclohexylmethyl)-9-[(6-phenoxypyridin-3-yl)methyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione dihydrochloride
Show/Hide
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C31H44Cl2N4O3
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1
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| 1 |
IC50 = 21 nM
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CP0478266
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methyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-(cyclopentylmethyl)carbamate
Show/Hide
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C30H43N3O4S
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1
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| 1 |
IC50 = 22 nM
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CP0494907
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methyl N-(cyclopentylmethyl)-N-[1-[[(3S,4S)-1-(naphthalene-1-carbonyl)-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]carbamate
Show/Hide
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C35H43N3O3
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1
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| 1 |
IC50 = 22 nM
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CP0436181
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N-[4-[3-[4-[ethyl-[2-(4-methylsulfonylphenyl)acetyl]amino]piperidin-1-yl]-1-phenylpropyl]phenyl]-2,2-dimethylpropanamide
Show/Hide
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C36H47N3O4S
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1
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| 1 |
IC50 = 22 nM
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CP0533092
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(S)-5-(4-(5-butyl-3-methyl-2-oxo-1-oxa-3,9-diazaspiro[5.5]undecan-9-yl)-4-methylpiperidine-1-carbonyl)-4,6-dimethylpicolinonitrile
Show/Hide
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C28H41N5O3
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1
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| 1 |
IC50 = 22 nM
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CP0470562
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Allyl-{1-[3-phenyl-4-(4-phenyl-imidazol-1-yl)-butyl]-piperidin-4-yl}-carbamic acid 4-nitro-benzyl ester
Show/Hide
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C35H39N5O4
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1
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| 1 |
IC50 = 23 nM
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CP0384857
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((3S,4S)-3-((4-(allyl(pyridin-3-yl)amino)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)(cyclohexyl)methanone
Show/Hide
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C31H42N4O
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1
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| 1 |
IC50 = 23 nM
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CP0391858
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(R)-2-((3S,4S)-3-((4-(1H-imidazo[4,5-b]pyridin-1-yl)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)-2-cyclohexylacetic acid
Show/Hide
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C30H39N5O2
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1
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| 1 |
IC50 = 23 nM
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CP0473756
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(E)-methyl N-cyano-4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)-4-phenylpiperidine-1-carbimidothioate
Show/Hide
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C31H38N6S
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1
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| 1 |
IC50 = 23 nM
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CP0491940
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2-(5-chlorothiophen-2-yl)-2-(4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)-4-phenylpiperidin-1-yl)acetic acid
Show/Hide
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C34H39ClN4O2S
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1
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| 1 |
IC50 = 23 nM
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CP0429870
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(5S)-9-[(3aR,6aS)-2-(4,6-dimethylpyrimidine-5-carbonyl)-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-yl]-5-butyl-3-[(4-propan-2-yloxycyclohexyl)methyl]-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
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C36H57N5O4
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1
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| 1 |
IC50 = 23 nM
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CP0880570
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(R)-1-butyl-3-((S)-1-hydroxy-2-methyl-propyl)-9-(4-phenoxy-benzyl)-1,4,9-triaza-spiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C29H40ClN3O4
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2
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| 1 |
IC50 = 24 nM
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| 2 |
IC50 = 210 nM
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CP0528401
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N,N-diethyl-4-[2-[(1R,5S)-3-(2-methylbenzimidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl]ethyl]-4-phenylpiperidine-1-carboxamide
Show/Hide
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C33H45N5O
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1
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| 1 |
IC50 = 24 nM
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CP0452100
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4-butyl-8-(1-(2,6-dimethylbenzoyl)piperidin-4-yl)-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Show/Hide
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C31H47N3O4
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1
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| 1 |
IC50 = 24 nM
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CP0533359
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(+/-)-5-(4-(5-butyl-2-oxo-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,9-diazaspiro[5.5]undecan-9-yl)-4-methylpiperidine-1-carbonyl)-4,6-dimethylpicolinonitrile
Show/Hide
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C33H49N5O4
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1
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| 1 |
IC50 = 24 nM
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CP0100407
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Allyl-[1-(4-benzoimidazol-1-yl-3-phenyl-butyl)-piperidin-4-yl]-carbamic acid benzyl ester
Show/Hide
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C33H38N4O2
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1
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| 1 |
IC50 = 25 nM
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CP0157022
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N-[(2S)-2-(3-chlorophenyl)-4-[4-(4-fluorophenyl)piperidin-1-yl]butyl]-N-methylbenzenesulfonamide
Show/Hide
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C28H32ClFN2O2S
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1
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| 1 |
IC50 = 25 nM
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CP0446493
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(R)-N-ethyl-2-(4-(methylsulfonyl)phenyl)-N-(1-(3-(4-(methylsulfonyl)phenyl)-3-(3,4,5-trifluorophenyl)propyl)piperidin-4-yl)acetamide
Show/Hide
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C32H37F3N2O5S2
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1
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| 1 |
IC50 = 25 nM
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CP0449531
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(R)-N-ethyl-N-(1-(3-(3-methoxyphenyl)-3-(4-(methylsulfonyl)phenyl)propyl)piperidin-4-yl)-2-(4-(methylsulfonyl)phenyl)acetamide
Show/Hide
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C33H42N2O6S2
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1
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| 1 |
IC50 = 25 nM
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CP0956775
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(S)-(-)-10-{4-[2-(butoxy)ethoxy]phenyl}-1-propyl-N-(4-{[(1-propyl-1H-imidazol-5-yl)methyl]sulfinyl}phenyl)-1,2,3,4,5,6-hexahydro-1-benzazecine-7-carboxamide
Show/Hide
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C42H54N4O4S
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1
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| 1 |
IC50 = 25 nM
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CP0452103
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5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4-methylpiperidin-4-yl)-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
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C31H49N5O4
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1
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| 1 |
IC50 = 25 nM
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CP0463746
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(5S)-5-butyl-9-((3aR,6aS)-2-(4,6-dimethylpyrimidine-5-carbonyl)-5-methyloctahydrocyclopenta[c]pyrrol-5-yl)-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
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C33H51N5O4
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1
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| 1 |
IC50 = 25 nM
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CP0411275
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1-acetyl-N-(3-chlorophenyl)-N-[3-[4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]propyl]piperidine-4-carboxamide
Show/Hide
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C29H38ClFN4O2
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1
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| 1 |
IC50 = 25.1 nM
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CP0445031
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1-acetyl-N-(3-chloro-4-methylphenyl)-N-[3-[2-methyl-4-[(4-methylphenyl)methyl]piperazin-1-yl]propyl]piperidine-4-carboxamide
Show/Hide
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C31H43ClN4O2
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1
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| 1 |
IC50 = 25.1 nM
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CP0519316
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1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-[(4-chlorophenyl)methyl]piperidine-4-carboxamide
Show/Hide
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C30H38Cl2N4O3
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1
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| 1 |
IC50 = 25.53 nM
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CP0448462
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[4-[4-(4-chloroanilino)piperidin-1-yl]-4-methylpiperidin-1-yl]-(2,6-dimethylphenyl)methanone
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C26H34ClN3O
|
1
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| 1 |
IC50 = 25.7 nM
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CP0439873
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1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-benzylpiperidine-4-carboxamide
Show/Hide
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C30H39ClN4O3
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1
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| 1 |
IC50 = 25.73 nM
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CP0430770
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1'-[4-phenyl-1-phenylsulfonyl-(3S,4S)-tetrahydro-1H-3-pyrrolylmethyl]spiro[2,3-dihydrobenzo[b]thiophene-3,4'-(hexahydropyridine)1-oxide]
Show/Hide
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C29H32N2O3S2
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1
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| 1 |
IC50 = 26 nM
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CP0495944
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N-[1-[3-(4-acetamidophenyl)-3-phenylpropyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C33H41N3O4S
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1
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| 1 |
IC50 = 26 nM
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CP0421098
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1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-ethyl-N-(2-phenylethyl)piperidine-4-carboxamide
Show/Hide
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C33H45ClN4O3
|
1
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| 1 |
IC50 = 26.37 nM
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CP0432869
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Allyl-[1-(4-indazol-2-yl-3-phenyl-butyl)-piperidin-4-yl]-carbamic acid 4-nitro-benzyl ester
Show/Hide
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C33H37N5O4
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1
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| 1 |
IC50 = 27 nM
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CP0479279
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(2S,3aS,4S,5S)-2,4-Diphenyl-5-(4-phenyl-piperidin-1-ylmethyl)-hexahydro-pyrrolo[1,2-b]isoxazole
Show/Hide
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C30H34N2O
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1
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| 1 |
IC50 = 27 nM
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CP0452104
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(5S)-5-butyl-3-((4,4-difluorocyclohexyl)methyl)-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4-methylpiperidin-4-yl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
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C32H49F2N5O3
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1
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| 1 |
IC50 = 27 nM
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CP0383111
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(5S)-9-[(3aS,6aR)-2-(4,6-dimethylpyrimidine-5-carbonyl)-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-yl]-5-butyl-3-[(4-cyclopropyloxycyclohexyl)methyl]-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
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C36H55N5O4
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1
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| 1 |
IC50 = 27 nM
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CP0377212
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4-((3-allyl-3-((1R,3R,5S)-8-(((3S,4R)-1-(cyclopentanecarbonyl)-4-(3-fluorophenyl)-4-hydroxypyrrolidin-3-yl)methyl)-8-azabicyclo[3.2.1]octan-3-yl)ureido)methyl)-N-methylbenzenesulfonamide
Show/Hide
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C36H48FN5O5S
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1
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| 1 |
IC50 = 27.1 nM
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CP0448046
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(2,6-Dimethyl-phenyl)-[4'-methyl-4-(4-trifluoromethyl-phenylamino)-[1,4']bipiperidinyl-1'-yl]-methanone
Show/Hide
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C27H34F3N3O
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1
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| 1 |
IC50 = 27.3 nM
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CP0390754
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N-[(3R)-3-[4-[(5R)-3-cyclohexyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
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C31H44N6O2
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1
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| 1 |
IC50 = 27.6 nM
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CP0511134
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Allyl-[1-(3-phenyl-4-[1,2,4]triazol-1-yl-butyl)-piperidin-4-yl]-carbamic acid 4-nitro-benzyl ester
Show/Hide
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C28H34N6O4
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1
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| 1 |
IC50 = 28 nM
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CP0377356
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N-methyl-N-[(2S)-2-methyl-4-(1-methyl-2-oxo-4,4a,5,7,8,8a-hexahydro-3H-1,6-naphthyridin-6-yl)-2-phenylbutyl]benzenesulfonamide
Show/Hide
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C27H37N3O3S
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1
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| 1 |
IC50 = 28 nM
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CP0448616
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N-ethyl-N-[1-[3-(4-methylphenyl)-3-phenylpropyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C32H40N2O3S
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1
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| 1 |
IC50 = 28 nM
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CP0878447
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1-butyl-3-(2-hydroxy-2-methyl-propyl)-9-(4-phenoxy-benzyl)-1,4,9-triaza-spiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C29H40ClN3O4
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2
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| 1 |
IC50 = 28 nM
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| 2 |
IC50 = 79 nM
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CP0918699
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4-(4-{[(3S)-1-Butyl-3-(cyclohexylmethyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl]methyl}phenoxy)benzenesulfonamide hydrochloride
Show/Hide
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C32H45ClN4O5S
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1
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| 1 |
IC50 = 28 nM
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CP0329264
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[4-[4-(4-bromoanilino)piperidin-1-yl]-4-methylpiperidin-1-yl]-(2,6-dimethylphenyl)methanone
Show/Hide
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C26H34BrN3O
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1
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| 1 |
IC50 = 28.3 nM
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CP0413857
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4-[4-[[4-[(5R)-3-cyclohexyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]phenoxy]benzamide
Show/Hide
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C34H40N4O3
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1
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| 1 |
IC50 = 28.8 nM
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CP0387904
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(R)-3-cyclobutyl-2-((3S,4S)-3-(3-fluorophenyl)-4-((4-(imidazo[1,2-a]pyrazin-2-yl)piperidin-1-yl)methyl)pyrrolidin-1-yl)propanoic acid
Show/Hide
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C29H36FN5O2
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1
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| 1 |
IC50 = 29 nM
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CP0874446
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(R)-1-butyl-3-isobutyl-9-(4-phenoxy-benzyl)-1,4,9-triaza-spiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C29H40ClN3O3
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2
|
| 1 |
IC50 = 29 nM
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| 2 |
IC50 = 130 nM
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CP0851295
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endo-4-(3,4-Dichloro-phenyl)-4-{2-[3-(2-methyl-benzoimidazol-1-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}-piperidine-1-carboxylic acid tert-butyl ester
Show/Hide
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C33H42Cl2N4O2
|
1
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| 1 |
IC50 = 29.51 nM
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CP0306548
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N-[(2S)-2-(3-chlorophenyl)-4-(4-phenylpiperidin-1-yl)butyl]-N-methylbenzenesulfonamide
Show/Hide
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C28H33ClN2O2S
|
1
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| 1 |
IC50 = 30 nM
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CP0441403
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(2S,3aS,4S,5S)-2,5-Diphenyl-4-(4-phenyl-piperidin-1-ylmethyl)-hexahydro-pyrrolo[1,2-b]isoxazole
Show/Hide
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C30H34N2O
|
1
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| 1 |
IC50 = 30 nM
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CP0448229
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(4,6-Dimethyl-2-pyridin-4-yl-pyrimidin-5-yl)-(4-diphenylamino-4'-methyl-[1,4']bipiperidinyl-1'-yl)-methanone
Show/Hide
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C35H40N6O
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1
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| 1 |
IC50 = 30 nM
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CP0452101
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5-butyl-3-(cyclohexylmethyl)-9-(1-(2,6-dimethylbenzoyl)piperidin-4-yl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
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C33H51N3O3
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1
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| 1 |
IC50 = 30 nM
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CP0373700
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N-[(1S)-3-[(3aR,6aS)-5-(3,5-dimethyl-1,2,4-triazol-4-yl)-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-1-(3-fluorophenyl)propyl]oxane-4-carboxamide
Show/Hide
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C26H36FN5O2
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1
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| 1 |
IC50 = 30 nM
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CP0516449
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1-allyl-1-((1R,3S,5S)-8-(((3S,4R)-1-(cyclopentanecarbonyl)-4-(3-fluorophenyl)-4-hydroxypyrrolidin-3-yl)methyl)-8-azabicyclo[3.2.1]octan-3-yl)-3-(4-fluorobenzyl)urea
Show/Hide
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C35H44F2N4O3
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1
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| 1 |
IC50 = 30 nM
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CP0534718
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4-nitrobenzyl allyl(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-(4-fluorophenyl)-4-hydroxypyrrolidin-3-yl)methyl)piperidin-4-yl)carbamate
Show/Hide
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C33H41FN4O6
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1
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| 1 |
IC50 = 30 nM
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CP0445032
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1-acetyl-N-(3-chloro-4-methylphenyl)-N-[3-[4-(4-fluorobenzoyl)-2-methylpiperazin-1-yl]propyl]piperidine-4-carboxamide
Show/Hide
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C30H38ClFN4O3
|
1
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| 1 |
IC50 = 30 nM
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CP0429487
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1-acetyl-N-(3-chloro-4-methylphenyl)-N-[3-[4-[(2-fluorophenyl)methyl]-2-methylpiperazin-1-yl]propyl]piperidine-4-carboxamide
Show/Hide
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C30H40ClFN4O2
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1
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| 1 |
IC50 = 30.1 nM
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CP0532407
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methyl N-[1-[[(3S,4S)-1-benzoyl-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-(cyclopentylmethyl)carbamate
Show/Hide
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C31H41N3O3
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1
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| 1 |
IC50 = 31 nM
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CP0377974
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(4,6-Dimethyl-2-phenyl-pyrimidin-5-yl)-(4-diphenylamino-4'-methyl-[1,4']bipiperidinyl-1'-yl)-methanone
Show/Hide
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C36H41N5O
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1
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| 1 |
IC50 = 31 nM
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CP0446557
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N-methyl-N-[(2S)-4-[4-[(5R)-2-oxo-5-phenyl-1,3-oxazolidin-3-yl]piperidin-1-yl]-2-phenylbutyl]benzenesulfonamide
Show/Hide
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C31H37N3O4S
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1
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| 1 |
IC50 = 31.9 nM
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CP0491613
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2-[(3S,4S)-3-Phenyl-4-(4-phenyl-piperidin-1-ylmethyl)-pyrrolidine-1-carbonyl]-benzoic acid methyl ester
Show/Hide
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C31H34N2O3
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1
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| 1 |
IC50 = 32 nM
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CP0686698
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Allyl-(1-{3-(3-chloro-phenyl)-4-[(R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-imidazolidin-1-yl]-3-methyl-butyl}-piperidin-4-yl)-carbamic acid benzyl ester
Show/Hide
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C39H44ClN5O4
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1
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| 1 |
IC50 = 32 nM
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CP0436259
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(R)-N-(1-(3-(2,5-difluorophenyl)-3-(4-(methylsulfonyl)phenyl)propyl)piperidin-4-yl)-N-ethyl-2-(4-(methylsulfonyl)phenyl)acetamide
Show/Hide
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C32H38F2N2O5S2
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1
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| 1 |
IC50 = 32 nM
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CP0431264
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N-cyclopropyl-N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C32H38N2O3S
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2
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| 1 |
IC50 = 32 nM
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| 2 |
IC50 = 51 nM
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CP0524633
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furan-3-yl-[(3S,4S)-3-phenyl-4-[(4-phenylpiperidin-1-yl)methyl]pyrrolidin-1-yl]methanone
Show/Hide
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C27H30N2O2
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1
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| 1 |
IC50 = 33 nM
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CP0418988
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(3a'S,4'S,5'S)-5'-phenyl-4'-((4-phenylpiperidin-1-yl)methyl)tetrahydro-3'H-spiro[cyclohexane-1,2'-pyrrolo[1,2-b]isoxazole]
Show/Hide
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C29H38N2O
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1
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| 1 |
IC50 = 33 nM
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CP0509811
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N-cyclopropyl-N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-2-(4-sulfamoylphenyl)acetamide
Show/Hide
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C31H37N3O3S
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1
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| 1 |
IC50 = 33 nM
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CP0919572
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4-(4-{[(3S)-1-Butyl-3-(cyclohexylmethyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl]methyl}phenoxy)-N-methylbenzamidehydrochloride
Show/Hide
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C34H47ClN4O4
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1
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| 1 |
IC50 = 33 nM
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CP0504453
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1-benzoyl-N-(3-chloro-4-methylphenyl)-N-[3-[4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]propyl]piperidine-4-carboxamide
Show/Hide
|
C35H42ClFN4O2
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1
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| 1 |
IC50 = 33.2 nM
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CP0478315
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cyclohexyl-[(3S,4S)-3-phenyl-4-[(4-phenylpiperidin-1-yl)methyl]pyrrolidin-1-yl]methanone
Show/Hide
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C29H38N2O
|
1
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| 1 |
IC50 = 34 nM
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CP0429869
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(5S)-9-[(3aS,6aR)-2-(2,4-dimethylpyridine-3-carbonyl)-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-yl]-5-butyl-3-[(4-ethoxycyclohexyl)methyl]-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
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C36H56N4O4
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1
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| 1 |
IC50 = 34 nM
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CP0291728
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(2S)-2-(3,4-dichlorophenyl)-1-[(N-methyl-N-phenylsulfonyl)amino]-4-[spiro(2,3-dihydrobenzthiophene-3,40-piperidin-10-yl)]butane S-oxide
Show/Hide
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C29H32Cl2N2O3S2
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1
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| 1 |
IC50 = 35 nM
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CP0502501
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1'-[3-(3-chlorophenyl)-4-methyl(phenyl)sulfonamidobutyl]-1-oxospiro[1,2,3,4-tetrahydroisoquinoline-4,4'-(hexahydropyridine)]
Show/Hide
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C30H34ClN3O3S
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1
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| 1 |
IC50 = 35 nM
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CP0549579
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1-[3-(3-chlorophenyl)-4-methyl(phenyl)sulfonamidobutyl]-2'-oxospiro[hexahydropyridine-4,4'-(1',2',3',4'-tetrahydroquinoline)]
Show/Hide
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C30H34ClN3O3S
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1
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| 1 |
IC50 = 35 nM
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CP0380572
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ethyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-(cyclohexylmethyl)carbamate
Show/Hide
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C32H47N3O4S
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1
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| 1 |
IC50 = 35 nM
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CP0463448
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2-(phenyl)-1-[(N-methyl-N-phenylsulfonyl)amino]-4-[spiro(2,3-dihydrobenzthiophene-3,40-piperidin-10-yl)]butane S-oxide
Show/Hide
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C29H34N2O3S2
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1
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| 1 |
IC50 = 35 nM
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CP0522554
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1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-1-ethyl-3-(3-methyl-benzyl)-urea
Show/Hide
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C31H39N3O
|
1
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| 1 |
IC50 = 35 nM
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CP0496151
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N-[(1S)-3-[(3aS,6aR)-5-(3,5-dimethyl-1,2,4-triazol-4-yl)-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-1-(3-fluorophenyl)propyl]oxolane-3-carboxamide
Show/Hide
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C25H34FN5O2
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1
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| 1 |
IC50 = 35 nM
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CP0902375
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rac-1-Butyl-3-(cyclohexylmethyl)-9-[(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)methyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione dihydrochloride
Show/Hide
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C31H47Cl2N5O2
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1
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| 1 |
IC50 = 35 nM
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CP0523661
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1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-[(4-fluorophenyl)methyl]piperidine-4-carboxamide
Show/Hide
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C30H38ClFN4O3
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1
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| 1 |
IC50 = 35.47 nM
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CP0446558
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N-methyl-N-[(2S)-4-[4-[(4S,5R)-4-methyl-2-oxo-5-phenyl-1,3-oxazolidin-3-yl]piperidin-1-yl]-2-phenylbutyl]benzenesulfonamide
Show/Hide
|
C32H39N3O4S
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1
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| 1 |
IC50 = 36.7 nM
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CP0492418
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N-[1-[3-(1-acetylpiperidin-4-yl)-3-phenylpropyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C32H45N3O4S
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1
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| 1 |
IC50 = 37 nM
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CP0297706
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4-(methylsulfonyl)benzyl allyl(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-yl)carbamate
Show/Hide
|
C34H45N3O6S
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1
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| 1 |
IC50 = 37.3 nM
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CP0236507
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1-allyl-3-benzyl-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-yl)urea
Show/Hide
|
C33H44N4O3
|
1
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| 1 |
IC50 = 37.7 nM
|
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CP0464628
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N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-ethyl-2-(4-sulfamoylphenyl)acetamide
Show/Hide
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C30H37N3O3S
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1
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| 1 |
IC50 = 38 nM
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CP0463748
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(S)-N-(3-(4-(3,5-dimethyl-4H-1,2,4-triazol-4-yl)piperidin-1-yl)-1-(3-fluorophenyl)propyl)-4,4-difluorocyclohexanecarboxamide
Show/Hide
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C25H34F3N5O
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1
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| 1 |
IC50 = 38 nM
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CP0477604
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1-allyl-1-(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-(4-fluorophenyl)-4-hydroxypyrrolidin-3-yl)methyl)piperidin-4-yl)-3-(4-(trifluoromethyl)benzyl)urea
Show/Hide
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C34H42F4N4O3
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1
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| 1 |
IC50 = 38.3 nM
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CP0524709
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N-ethyl-2-(4-methylsulfonylphenyl)-N-[1-[3-(4-methylsulfonylpiperazin-1-yl)-3-phenylpropyl]piperidin-4-yl]acetamide
Show/Hide
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C30H44N4O5S2
|
1
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| 1 |
IC50 = 39 nM
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CP0409018
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N-[3-[4-(3-cyclohexyl-2-oxo-5-thiophen-3-ylimidazolidin-1-yl)piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
|
C29H42N6O2S
|
1
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| 1 |
IC50 = 39 nM
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CP0037293
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1'-[3-(3,4-dichlorophenyl)-4-methyl(4-phenylphenyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
Show/Hide
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C35H36Cl2N2O3S2
|
1
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| 1 |
IC50 = 40 nM
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CP0509223
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1'-[3-(3,4-dichlorophenyl)-4-[4-methoxyphenyl(methyl)sulfonamido]-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
Show/Hide
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C30H34Cl2N2O4S2
|
1
|
| 1 |
IC50 = 40 nM
|
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CP0511233
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1'-[4-[4-chlorophenyl(methyl)sulfonamido]-3-(3,4-dichlorophenyl)-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
Show/Hide
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C29H31Cl3N2O3S2
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1
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| 1 |
IC50 = 40 nM
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CP0066349
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ethyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-ethylcarbamate
Show/Hide
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C27H39N3O4S
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1
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| 1 |
IC50 = 40 nM
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CP0528929
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methyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-ethylcarbamate
Show/Hide
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C26H37N3O4S
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1
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| 1 |
IC50 = 40 nM
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CP0464510
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(S)-N-(1-(3-(3,5-difluorophenyl)-3-(4-(methylsulfonyl)phenyl)propyl)piperidin-4-yl)-N-ethyl-2-(4-(methylsulfonyl)phenyl)acetamide
Show/Hide
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C32H38F2N2O5S2
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1
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| 1 |
IC50 = 40 nM
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CP0468400
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(E)-cyclopentyl N-cyano-4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)-4-phenylpiperidine-1-carbimidothioate
Show/Hide
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C35H44N6S
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1
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| 1 |
IC50 = 40 nM
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CP0927950
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N-[4-(4-{[(3S)-1-Butyl-3-(cyclohexylmethyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl]methyl}phenoxy)phenyl]methanesulfonamide hydrochloride
Show/Hide
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C33H47ClN4O5S
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1
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| 1 |
IC50 = 40 nM
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CP0453442
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cyclohexyl-[(3S,4S)-3-phenyl-4-[[4-(N-prop-2-enylanilino)piperidin-1-yl]methyl]pyrrolidin-1-yl]methanone
Show/Hide
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C32H43N3O
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1
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| 1 |
IC50 = 42 nM
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CP0442247
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1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-1-ethyl-3-(4-methoxy-benzyl)-urea
Show/Hide
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C31H39N3O2
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1
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| 1 |
IC50 = 42 nM
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CP0902263
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(S)-1-butyl-3-(cyclohexylmethyl)-9-(3-(4-hydroxyphenoxy)phenethyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C33H46ClN3O4
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1
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| 1 |
IC50 = 42 nM
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CP0919571
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(3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(4-hydroxyphenoxy)benzyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C32H44ClN3O4
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1
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| 1 |
IC50 = 42 nM
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CP0516401
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4'-phenyl-(3a'S,4'S,5'S)-spiro[cyclohexane-1,2'-perhydropyrrolo[1,2-b]isoxazole]-5-yl(4-phenylhexahydro-1-pyridinyl)methane
Show/Hide
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C29H38N2O
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1
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| 1 |
IC50 = 43 nM
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CP0498588
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N-[(1S)-3-[(3aR,6aS)-5-(3,5-dimethyl-1,2,4-triazol-4-yl)-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-yl]-1-(3-fluorophenyl)propyl]oxane-4-carboxamide
Show/Hide
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C26H36FN5O2
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1
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| 1 |
IC50 = 43 nM
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CP0373985
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(5S)-9-[(3aS,6aR)-2-(4,6-dimethylpyrimidine-5-carbonyl)-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-yl]-5-butyl-3-[(4-ethoxycyclohexyl)methyl]-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
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C35H55N5O4
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1
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| 1 |
IC50 = 44 nM
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CP0780618
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4-(4-(((R)-1-butyl-3-((S)-cyclohexyl(hydroxy)methyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl)methyl)phenoxy)benzoic acid hydrochloride
Show/Hide
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C33H44ClN3O6
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2
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| 1 |
IC50 = 44 nM
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| 2 |
IC50 = 44000 nM
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CP0407513
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4-[4-[[4-[(5R)-3-cyclohexyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]phenoxy]-N-methylbenzamide
Show/Hide
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C35H42N4O3
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1
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| 1 |
IC50 = 44.7 nM
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CP0316021
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1'-[3-(3-chlorophenyl)-4-methyl(phenyl)sulfonamidobutyl]-3-oxospiro[2,3-dihydro-1H-isoindole-1,4'-(hexahydropyridine)]
Show/Hide
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C29H32ClN3O3S
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1
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| 1 |
IC50 = 45 nM
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CP0504592
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5-((3aR,6aS)-5-((S)-4-((1S,2S)-2-ethoxy-5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl)-3-methylpiperazin-1-yl)octahydrocyclopenta[c]pyrrole-2-carbonyl)-4,6-dimethylpicolinonitrile
Show/Hide
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C33H40F3N5O2
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1
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| 1 |
IC50 = 45 nM
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CP0478260
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[(3S,4S)-3-phenyl-4-[(4-phenylpiperidin-1-yl)methyl]pyrrolidin-1-yl]-thiophen-2-ylmethanone
Show/Hide
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C27H30N2OS
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1
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| 1 |
IC50 = 46 nM
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CP0481428
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methyl N-[1-[[(3S,4S)-1-benzyl-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-(cyclopentylmethyl)carbamate
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C31H43N3O2
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1
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| 1 |
IC50 = 46 nM
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CP0423587
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benzyl N-[1-[[(2S,3aS,4S,5S)-2,5-diphenyl-2,3,3a,4,5,6-hexahydropyrrolo[1,2-b][1,2]oxazol-4-yl]methyl]piperidin-4-yl]-N-ethylcarbamate
Show/Hide
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C34H41N3O3
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1
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| 1 |
IC50 = 46 nM
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CP0464347
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(S)-N-ethyl-N-(1-(3-(4-fluorophenyl)-3-(4-(methylsulfonyl)phenyl)propyl)piperidin-4-yl)-2-(4-(methylsulfonyl)phenyl)acetamide
Show/Hide
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C32H39FN2O5S2
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1
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| 1 |
IC50 = 46 nM
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CP0403585
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2-(4-Dimethylsulfamoyl-phenyl)-N-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-N-methyl-acetamide
Show/Hide
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C31H39N3O3S
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1
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| 1 |
IC50 = 46 nM
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CP0420435
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(2-Bromo-phenyl)-[(3S,4S)-3-phenyl-4-(4-phenyl-piperidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone
Show/Hide
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C29H31BrN2O
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1
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| 1 |
IC50 = 48 nM
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CP0421380
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cyclobutyl-[(3S,4S)-3-phenyl-4-[(4-phenylpiperidin-1-yl)methyl]pyrrolidin-1-yl]methanone
Show/Hide
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C27H34N2O
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1
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| 1 |
IC50 = 48 nM
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CP0175199
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Allyl-{1-[4-(2-ethyl-benzoimidazol-1-yl)-3-phenyl-butyl]-piperidin-4-yl}-carbamic acid 4-nitro-benzyl ester
Show/Hide
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C35H41N5O4
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1
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| 1 |
IC50 = 48 nM
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CP0530092
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(4,6-Dimethyl-pyrimidin-5-yl)-(4-diphenylamino-[1,4']bipiperidinyl-1'-yl)-methanone
Show/Hide
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C29H35N5O
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1
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| 1 |
IC50 = 48 nM
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CP0379219
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1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-1-ethyl-3-(4-methanesulfonyl-benzyl)-urea
Show/Hide
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C31H39N3O3S
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1
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| 1 |
IC50 = 49 nM
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CP0388646
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1-acetyl-N-(3-chloro-4-methylphenyl)-N-[3-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]propyl]piperidine-4-carboxamide
Show/Hide
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C30H40ClFN4O2
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1
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| 1 |
IC50 = 49.9 nM
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CP0370161
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1'-[3-(3-chlorophenyl)-4-methyl(phenyl)sulfonamidobutyl]spiro[2,3-dihydro-1H-indole-3,4'-(hexahydropyridine)]
Show/Hide
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C29H34ClN3O2S
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1
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| 1 |
IC50 = 50 nM
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CP0837909
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9-(4-allyloxyphenylmethyl)-1-butyl-3-cyclohexyl-1,4,9-triazaspiro[5.5]undeca-2,5-dione hydrochloride
Show/Hide
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C29H44ClN3O3
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1
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| 1 |
IC50 = 50 nM
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CP0920758
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rac-1-Butyl-9-(4-phenoxybenzyl)-3-propyl-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C28H38ClN3O3
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1
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| 1 |
IC50 = 50 nM
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CP0390756
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(4R)-1-cyclohexyl-4-phenyl-3-[1-[(4-pyrimidin-5-ylphenyl)methyl]piperidin-4-yl]imidazolidin-2-one
Show/Hide
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C31H37N5O
|
1
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| 1 |
IC50 = 50.6 nM
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CP0465224
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4-{1-[(S)-1-(1-Carboxy-2-cyclopropyl-ethyl)-4-((R)-3-fluoro-phenyl)-pyrrolidin-3-ylmethyl]-piperidin-4-yl}-2-(4-fluoro-phenyl)-butyric acid
Show/Hide
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C32H40F2N2O4
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1
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| 1 |
IC50 = 51 nM
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CP0513961
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4-butyl-3-(cyclohexylmethyl)-8-(1-(2,6-dimethylbenzoyl)piperidin-4-yl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Show/Hide
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C32H49N3O3
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1
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| 1 |
IC50 = 51 nM
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CP0781851
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4-(4-(((S)-1-butyl-3-((S)-cyclohexyl(hydroxy)methyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl)methyl)phenoxy)benzoic acid hydrochloride
Show/Hide
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C33H44ClN3O6
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2
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| 1 |
IC50 = 51 nM
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| 2 |
IC50 = 51000 nM
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CP0531457
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(2-Chloro-phenyl)-[(3S,4S)-3-phenyl-4-(4-phenyl-piperidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone
Show/Hide
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C29H31ClN2O
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1
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| 1 |
IC50 = 52 nM
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CP0913150
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rac-1-Butyl-3-(cyclopentylmethyl)-9-(4-phenoxybenzyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C31H42ClN3O3
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1
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| 1 |
IC50 = 52 nM
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CP0918569
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(S)-1-butyl-3-((S)-1-hydroxy-2-methyl-propyl)-9-(4-phenoxy-benzyl)-1,4,9-triaza-spiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C29H40ClN3O4
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2
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| 1 |
IC50 = 53 nM
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| 2 |
IC50 = 150 nM
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CP0919399
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rac-1-(2-Butynyl)-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C29H36ClN3O3
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1
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| 1 |
IC50 = 54 nM
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CP0448515
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furan-2-yl-[(3S,4S)-3-phenyl-4-[(4-phenylpiperidin-1-yl)methyl]pyrrolidin-1-yl]methanone
Show/Hide
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C27H30N2O2
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1
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| 1 |
IC50 = 55 nM
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CP0394006
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(R)-N-(1-(3-(3-cyanophenyl)-3-(4-(methylsulfonyl)phenyl)propyl)piperidin-4-yl)-N-ethyl-2-(4-(methylsulfonyl)phenyl)acetamide
Show/Hide
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C33H39N3O5S2
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1
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| 1 |
IC50 = 56 nM
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CP0531886
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4-[(4R)-3-[1-[4-[(6-chloro-2,4-dimethylpyridine-3-carbonyl)amino]butan-2-yl]piperidin-4-yl]-2-oxo-4-phenylimidazolidin-1-yl]cyclohexane-1-carboxylic acid
Show/Hide
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C33H44ClN5O4
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1
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| 1 |
IC50 = 56 nM
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CP0403866
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6-chloro-N-[3-[4-[(5R)-3-ethyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]butyl]-2,4-dimethylpyridine-3-carboxamide
Show/Hide
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C28H38ClN5O2
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1
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| 1 |
IC50 = 56.6 nM
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CP0390752
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N-[3-[4-[5-(3-cyanophenyl)-3-cyclohexyl-2-oxoimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
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C32H43N7O2
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1
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| 1 |
IC50 = 56.9 nM
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CP0461344
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2-Ethyl-1-[(3S,4S)-3-phenyl-4-(4-phenyl-piperidin-1-ylmethyl)-pyrrolidin-1-yl]-butan-1-one
Show/Hide
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C28H38N2O
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1
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| 1 |
IC50 = 57 nM
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CP0919404
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4-{[(3S)-1-Butyl-3-(cyclohexylmethyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl]methyl}-N-phenylbenzamide hydrochloride
Show/Hide
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C33H45ClN4O3
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1
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| 1 |
IC50 = 57 nM
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CP0379585
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4-[4-[[4-[(5R)-3-cyclohexyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]phenoxy]-N,N-dimethylbenzamide
Show/Hide
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C36H44N4O3
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1
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| 1 |
IC50 = 57 nM
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CP0431265
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N-[1-[3-(3-chlorophenyl)-3-phenylpropyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C31H37ClN2O3S
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1
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| 1 |
IC50 = 58 nM
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CP0537785
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4-butyl-8-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4-methylpiperidin-4-yl)-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Show/Hide
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C30H47N5O4
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1
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| 1 |
IC50 = 58 nM
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CP0319093
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1'-[3-(3,4-dichlorophenyl)-4-methyl(4-nitrophenyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1,1-dioxide-3,4'-(hexahydropyridine)]
Show/Hide
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C29H31Cl2N3O6S2
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1
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| 1 |
IC50 = 60 nM
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CP0370162
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1'-[3-(3,4-dichlorophenyl)-4-methyl(2-naphthyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
Show/Hide
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C33H34Cl2N2O3S2
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1
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| 1 |
IC50 = 60 nM
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CP0497651
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1'-[3-(3,4-dichlorophenyl)-4-methyl(2-thienyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
Show/Hide
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C27H30Cl2N2O3S3
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1
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| 1 |
IC50 = 60 nM
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CP0392626
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2-(4-Cyano-phenyl)-N-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-N-methyl-acetamide
Show/Hide
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C30H33N3O
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1
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| 1 |
IC50 = 60 nM
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CP0395256
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(2,6-Dimethyl-phenyl)-(4-diphenylamino-[1,4']bipiperidinyl-1'-yl)-methanone
Show/Hide
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C31H37N3O
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1
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| 1 |
IC50 = 61 nM
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CP0537786
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(S)-5-butyl-9-(1-(2,4-dimethylnicotinoyl)-4-methylpiperidin-4-yl)-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
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C32H50N4O4
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1
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| 1 |
IC50 = 61 nM
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CP0504595
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5-((3aR,6aS)-5-((S)-5-butyl-2-oxo-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,9-diazaspiro[5.5]undecan-9-yl)-5-methyloctahydrocyclopenta[c]pyrrole-2-carbonyl)-4,6-dimethylpicolinonitrile
Show/Hide
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C35H51N5O4
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1
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| 1 |
IC50 = 61 nM
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CP0430906
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3-Benzyl-1-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-1-ethyl-urea
Show/Hide
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C30H37N3O
|
1
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| 1 |
IC50 = 62 nM
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CP0379625
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N-[3-[4-[3-cyclohexyl-5-(3-fluorophenyl)-2-oxoimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
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C31H43FN6O2
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1
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| 1 |
IC50 = 62.5 nM
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CP0403869
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4-[[4-[(5R)-3-cyclohexyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]-N-methylbenzamide
Show/Hide
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C29H38N4O2
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1
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| 1 |
IC50 = 62.7 nM
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CP0458590
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(R)-2-cyclohexyl-2-((3S,4S)-3-((4-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)acetic acid
Show/Hide
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C31H40N4O3
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1
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| 1 |
IC50 = 63 nM
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CP0941406
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exo-4-{2-[3-(2-Methyl-benzoimidazol-1-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}-4-phenyl-piperidine-1-carboxylic acid tert-butyl ester
Show/Hide
|
C33H44N4O2
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1
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| 1 |
IC50 = 63.1 nM
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CP0941408
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exo-4-{2-[3-(2-Methyl-benzoimidazol-1-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-ethyl}-4-phenyl-piperidine-1-carboxylic acid benzyl ester
Show/Hide
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C36H42N4O2
|
1
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| 1 |
IC50 = 63.1 nM
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CP0443488
|
1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-benzyl-N-methylpiperidine-4-carboxamide
Show/Hide
|
C31H41ClN4O3
|
1
|
| 1 |
IC50 = 64.07 nM
|
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CP0157020
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N-[(2S)-2-(3-chlorophenyl)-4-[4-(2-phenylethyl)piperidin-1-yl]butyl]-N-methylbenzenesulfonamide
Show/Hide
|
C30H37ClN2O2S
|
1
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| 1 |
IC50 = 65 nM
|
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CP0486942
|
(R)-3-cyclobutyl-2-((3S,4S)-3-(3-fluorophenyl)-4-((4-(imidazo[1,2-a]pyridin-2-yl)piperidin-1-yl)methyl)pyrrolidin-1-yl)propanoic acid
Show/Hide
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C30H37FN4O2
|
1
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| 1 |
IC50 = 65 nM
|
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CP0860204
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rac-N-(3-(4-(3-cyclohexyl-2-oxo-5-phenylimidazolidin-1-yl)piperidin-1-yl)butyl)-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
|
C31H44N6O2
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1
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| 1 |
IC50 = 65.7 nM
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CP0409464
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((3S,4S)-3-((4-(allyl(pyridin-4-yl)amino)piperidin-1-yl)methyl)-4-phenylpyrrolidin-1-yl)(cyclohexyl)methanone
Show/Hide
|
C31H42N4O
|
1
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| 1 |
IC50 = 66 nM
|
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CP0378348
|
2-(4-Cyano-phenyl)-N-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-N-ethyl-acetamide
Show/Hide
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C31H35N3O
|
1
|
| 1 |
IC50 = 66 nM
|
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CP0432712
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4-({1-[3-((3,4-dichlorophenyl){[1-(methylsulfonyl)piperidin-4-yl]carbonyl}amino)propyl]piperidin-4-yl}methyl)benzoic acid
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C29H37Cl2N3O5S
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1
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| 1 |
IC50 = 66 nM
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CP0468278
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phenyl-[(3S,4S)-3-phenyl-4-[(4-phenylpiperidin-1-yl)methyl]pyrrolidin-1-yl]methanone
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C29H32N2O
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1
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| 1 |
IC50 = 67 nM
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CP0950566
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(S)-(-)-10-{4-[2-(butoxy)ethoxy]phenyl}-1-isobutyl-N-(4-{[(1-propyl-1H-imidazol-5-yl)methyl]sulfinyl}phenyl)-1,2,3,4,5,6-hexahydro-1-benzazecine-7-carboxamide
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C43H56N4O4S
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1
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| 1 |
IC50 = 67 nM
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CP0448299
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(4-Diphenylamino-4'-methyl-[1,4']bipiperidinyl-1'-yl)-o-tolyl-methanone
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C31H37N3O
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1
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| 1 |
IC50 = 67 nM
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CP0212023
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1'-[4-methyl(phenyl)sulfonamido-3-phenylbutyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
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C29H34N2O3S2
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1
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| 1 |
IC50 = 68 nM
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CP0877557
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(S)-1-butyl-3-((R)-1-hydroxy-2-methyl-propyl)-9-(4-phenoxy-benzyl)-1,4,9-triaza-spiro[5.5]undecane-2,5-dione hydrochloride
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C29H40ClN3O4
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2
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| 1 |
IC50 = 68 nM
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| 2 |
IC50 = 400 nM
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CP0494670
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5-butyl-3-(cyclohexylmethyl)-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)piperidin-4-yl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
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C31H49N5O3
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1
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| 1 |
IC50 = 68 nM
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CP0440498
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1-phenyl-3-{1-[5'-phenyl-(3a'S,4'S,5'S)-spiro[cyclohexane-1,2'-perhydropyrrolo[1,2-b]isoxazole]-4-ylmethyl]hexahydro-4-pyridinyl}propane
Show/Hide
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C32H44N2O
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1
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| 1 |
IC50 = 69 nM
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CP0919568
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rac-1-[(2E)-2-Butenyl]-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
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C29H38ClN3O3
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1
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| 1 |
IC50 = 69 nM
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CP0244682
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1'-[4-[3-chlorophenyl(methyl)sulfonamido]-3-(3,4-dichlorophenyl)-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
Show/Hide
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C29H31Cl3N2O3S2
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1
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| 1 |
IC50 = 70 nM
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CP0439346
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1'-[3-(3,4-dichlorophenyl)-4-[1H-5-indolyl(methyl)sulfonamido]-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
Show/Hide
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C31H33Cl2N3O3S2
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1
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| 1 |
IC50 = 70 nM
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CP0074795
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N-[(2S)-2-(3-chlorophenyl)-4-[4-(2-methoxyphenyl)piperidin-1-yl]butyl]-N-methylbenzenesulfonamide
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C29H35ClN2O3S
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1
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| 1 |
IC50 = 70 nM
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CP0901062
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(3S)-1-Butyl-3-(cyclohexylmethyl)-9-[(6-phenylpyridin-3-yl)methyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione dihydrochloride
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C31H44Cl2N4O2
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1
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| 1 |
IC50 = 71 nM
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CP0439559
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1-(8-(2-(1-((1H-imidazol-2-yl)methyl)-4-phenylpiperidin-4-yl)ethyl)-8-azabicyclo[3.2.1]octan-3-yl)-2-methyl-1H-benzo[d]imidazole
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C32H40N6
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1
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| 1 |
IC50 = 74 nM
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CP0466475
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1-[1-[4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-3-[(1S)-1-phenylethyl]-1-propylurea
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C34H46N4O3S
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1
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| 1 |
IC50 = 75 nM
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CP0481238
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1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-[(4-cyanophenyl)methyl]piperidine-4-carboxamide
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C31H38ClN5O3
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1
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| 1 |
IC50 = 75.3 nM
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CP0452102
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5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)piperidin-4-yl)-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
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C30H47N5O4
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1
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| 1 |
IC50 = 76 nM
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CP0481237
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1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-(2-phenylethyl)piperidine-4-carboxamide
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C31H41ClN4O3
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1
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| 1 |
IC50 = 76.03 nM
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CP0892602
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(1-{3-(3-Chloro-phenyl)-4-[(R)-4-(1H-indol-3-ylmethyl)-2,5-dioxo-imidazolidin-1-yl]-3-methyl-butyl}-piperidin-4-yl)-ethyl-carbamic acid benzyl ester
Show/Hide
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C38H44ClN5O4
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1
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| 1 |
IC50 = 77 nM
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CP0431266
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N-[1-[3-(3,4-dichlorophenyl)-3-phenylpropyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
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C31H36Cl2N2O3S
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1
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| 1 |
IC50 = 78 nM
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CP0921642
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(S)-1-butyl-3-(cyclohexylmethyl)-9-(3-(p-tolyloxy)phenethyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
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C34H48ClN3O3
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1
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| 1 |
IC50 = 79 nM
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CP0847334
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(3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(4-methylphenoxy)benzyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C33H46ClN3O3
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1
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| 1 |
IC50 = 79 nM
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CP0927948
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(3S)-1-Butyl-3-neopentyl-9-(4-phenoxybenzyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
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C30H42ClN3O3
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1
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| 1 |
IC50 = 79 nM
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CP0379624
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N-[3-[4-[3-cyclohexyl-5-(3,5-dimethylphenyl)-2-oxoimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
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C33H48N6O2
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1
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| 1 |
IC50 = 79.6 nM
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CP0399398
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1'-[4-[2-chlorophenyl(methyl)sulfonamido]-3-(3,4-dichlorophenyl)-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
Show/Hide
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C29H31Cl3N2O3S2
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1
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| 1 |
IC50 = 80 nM
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CP0491266
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(S)-3-(4-(5-butyl-2-oxo-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,9-diazaspiro[5.5]undecan-9-yl)-4-methylpiperidine-1-carbonyl)-2,4-dimethylpyridine 1-oxide
Show/Hide
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C32H50N4O5
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1
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| 1 |
IC50 = 80 nM
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CP0904689
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(3S)-9-(4-Benzoylbenzyl)-1-butyl-3-(cyclohexylmethyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C33H44ClN3O3
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1
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| 1 |
IC50 = 81 nM
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CP0399229
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N-[1-[3-(4-acetylpiperidin-1-yl)-3-phenylpropyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
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C32H45N3O4S
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1
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| 1 |
IC50 = 83 nM
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CP0428020
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N-ethyl-2-(4-methylsulfonylphenyl)-N-[1-[3-phenyl-3-(4-phenylphenyl)propyl]piperidin-4-yl]acetamide
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C37H42N2O3S
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1
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| 1 |
IC50 = 85 nM
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CP0500768
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4N-ethyl-4N-[benzyloxycarbonyl]-1-[5'-phenyl-(3a'S,4'S,5'S)-spiro[cyclohexane-1,2'-perhydropyrrolo[1,2-b]isoxazole]-4-ylmethyl]hexahydro-4-pyridinamine
Show/Hide
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C33H45N3O3
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1
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| 1 |
IC50 = 86 nM
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CP0907139
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(S)-1-butyl-3-(cyclohexylmethyl)-9-(3-(phenylsulfonyl)phenethyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C33H46ClN3O4S
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1
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| 1 |
IC50 = 86 nM
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CP0919403
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(3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(phenylsulfonyl)-benzyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C32H44ClN3O4S
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1
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| 1 |
IC50 = 86 nM
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CP0529563
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1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-[2-(4-chlorophenyl)ethyl]piperidine-4-carboxamide
Show/Hide
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C31H40Cl2N4O3
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1
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| 1 |
IC50 = 86.7 nM
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CP0529893
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Biphenyl-2-yl-[(3S,4S)-3-phenyl-4-(4-phenyl-piperidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone
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C35H36N2O
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1
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| 1 |
IC50 = 89 nM
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CP0502565
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tert-butyl N-[4-[3-[4-[ethyl-[2-(4-methylsulfonylphenyl)acetyl]amino]piperidin-1-yl]-1-(3-fluorophenyl)propyl]phenyl]carbamate
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C36H46FN3O5S
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1
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| 1 |
IC50 = 89 nM
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CP0533357
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5-butyl-9-(1-(2,6-dimethylbenzoyl)piperidin-4-yl)-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
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C32H49N3O4
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1
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| 1 |
IC50 = 89 nM
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CP0074799
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1'-[3-(3,4-dichlorophenyl)-4-methyl(8-quinolyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
Show/Hide
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C32H33Cl2N3O3S2
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1
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| 1 |
IC50 = 90 nM
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CP0445875
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N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-methyl-2-(4-sulfamoylphenyl)acetamide
Show/Hide
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C29H35N3O3S
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1
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| 1 |
IC50 = 91 nM
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CP0902264
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(S)-1-butyl-3-(cyclohexylmethyl)-9-(3-(4-fluorophenoxy)phenethyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C33H45ClFN3O3
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1
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| 1 |
IC50 = 92 nM
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CP0373984
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(4,6-dimethylpyrimidin-5-yl)((3aR,6aS)-5-((S)-4-((1S,2S)-2-ethoxy-5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl)-3-methylpiperazin-1-yl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)methanone
Show/Hide
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C31H40F3N5O2
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1
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| 1 |
IC50 = 92 nM
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CP0912202
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(3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(4-fluorophenoxy)benzyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C32H43ClFN3O3
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1
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| 1 |
IC50 = 92 nM
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CP0413838
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3-[4-[[4-[(5R)-3-cyclohexyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]phenoxy]benzoic acid
Show/Hide
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C34H39N3O4
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1
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| 1 |
IC50 = 92.8 nM
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CP0555821
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1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-[(4-chlorophenyl)methyl]-N-ethylpiperidine-4-carboxamide
Show/Hide
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C32H42Cl2N4O3
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1
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| 1 |
IC50 = 93.53 nM
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CP0497938
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(3-Chloro-phenyl)-[(3S,4S)-3-phenyl-4-(4-phenyl-piperidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone
Show/Hide
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C29H31ClN2O
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1
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| 1 |
IC50 = 94 nM
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CP0528948
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(2-Fluoro-phenyl)-[(3S,4S)-3-phenyl-4-(4-phenyl-piperidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone
Show/Hide
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C29H31FN2O
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1
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| 1 |
IC50 = 96 nM
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CP0438128
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[(3S,4S)-3-phenyl-4-[(4-phenylpiperidin-1-yl)methyl]pyrrolidin-1-yl]-[2-(trifluoromethyl)phenyl]methanone
Show/Hide
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C30H31F3N2O
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1
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| 1 |
IC50 = 97 nM
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CP0507124
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(S)-5-butyl-9-(1-(4,6-dimethyl-2-(trifluoromethyl)pyrimidine-5-carbonyl)-4-methylpiperidin-4-yl)-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
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C32H48F3N5O4
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1
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| 1 |
IC50 = 97 nM
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CP0383110
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(2,4-dimethylpyridin-3-yl)((3aR,6aS)-5-((S)-4-((1S,2S)-2-ethoxy-5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl)-3-methylpiperazin-1-yl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)methanone
Show/Hide
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C32H41F3N4O2
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1
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| 1 |
IC50 = 98 nM
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CP0044847
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1'-[3-(3,4-dichlorophenyl)-4-methyl(phenyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1,1-dioxide-3,4'-(hexahydropyridine)]
Show/Hide
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C29H32Cl2N2O4S2
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1
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| 1 |
IC50 = 100 nM
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CP0244681
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1'-[3-(3,4-dichlorophenyl)-4-methyl(3-pyridyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
Show/Hide
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C28H31Cl2N3O3S2
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1
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| 1 |
IC50 = 100 nM
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CP0316025
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1'-[4-cyclohexyl(methyl)sulfonamido-3-(3,4-dichlorophenyl)-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
Show/Hide
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C29H38Cl2N2O3S2
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1
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| 1 |
IC50 = 100 nM
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CP0316026
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1N-[2-(3,4-dichlorophenyl)-4-spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]-1-yl-(2S)-butyl]-1N-methyl-1-octanesulfonamide
Show/Hide
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C28H36Cl2N2O3S2
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1
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| 1 |
IC50 = 100 nM
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CP0926193
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(R)-3-[2-(3-Chloro-phenyl)-2-methyl-4-(4-phenyl-piperidin-1-yl)-butyl]-5-(1H-indol-3-ylmethyl)-imidazolidine-2,4-dione
Show/Hide
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C34H37ClN4O2
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1
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| 1 |
IC50 = 100 nM
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CP0244680
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1'-[3-(3-chlorophenyl)-4-methyl(phenyl)sulfonamidobutyl]-2-methyl-3-oxospiro[2,3-dihydro-1H-isoindole-1,4'-(hexahydropyridine)]
Show/Hide
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C30H34ClN3O3S
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1
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| 1 |
IC50 = 100 nM
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CP0316020
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1'-[3-(3-chlorophenyl)-4-methyl(phenyl)sulfonamidobutyl]-3-hydroxyspiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]
Show/Hide
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C30H35ClN2O3S
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1
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| 1 |
IC50 = 100 nM
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CP0076427
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methyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-benzylcarbamate
Show/Hide
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C31H39N3O4S
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1
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| 1 |
IC50 = 100 nM
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CP0389838
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N-[1-[(3R)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-propylbenzamide
Show/Hide
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C32H41N3O3S
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1
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| 1 |
IC50 = 100 nM
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CP0528862
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1-[1-[4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-3-benzylurea
Show/Hide
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C30H38N4O3S
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1
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| 1 |
IC50 = 100 nM
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CP0392729
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2-(3-(1-(((3S,4S)-1-(cyclohexylmethyl)-4-phenylpyrrolidin-3-yl)methyl)-4-hydroxypiperidin-4-yl)propyl)benzoic acid
Show/Hide
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C33H46N2O3
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1
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| 1 |
IC50 = 100 nM
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CP0524389
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(R)-Cyclohexyl-{(3S,4S)-3-[4-(4-oxo-4H-quinazolin-1-yl)-piperidin-1-ylmethyl]-4-phenyl-pyrrolidin-1-yl}-acetic acid
Show/Hide
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C32H40N4O3
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1
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| 1 |
IC50 = 100 nM
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CP0464632
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3-Benzyl-1-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-1-methyl-urea
Show/Hide
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C29H35N3O
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1
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| 1 |
IC50 = 100 nM
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CP0533091
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4-butyl-3-(cyclohexylmethyl)-8-(1-(2-methylbenzoyl)piperidin-4-yl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Show/Hide
|
C31H47N3O3
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1
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| 1 |
IC50 = 100 nM
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CP0533358
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(R)-5-butyl-9-(1-(4,6-dimethylpyrimidine-5-carbonyl)-4-methylpiperidin-4-yl)-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
Show/Hide
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C31H49N5O4
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1
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| 1 |
IC50 = 100 nM
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CP0429164
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(4-Diphenylamino-4'-methyl-[1,4']bipiperidinyl-1'-yl)-(1H-indol-4-yl)-methanone
Show/Hide
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C32H36N4O
|
1
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| 1 |
IC50 = 102 nM
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CP0515570
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N-[1-[3-(4-aminophenyl)-3-(3-fluorophenyl)propyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C31H38FN3O3S
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1
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| 1 |
IC50 = 105 nM
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CP0522275
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(R)-N-ethyl-N-(1-(3-(3-isopropylphenyl)-3-(4-(methylsulfonyl)phenyl)propyl)piperidin-4-yl)-2-(4-(methylsulfonyl)phenyl)acetamide
Show/Hide
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C35H46N2O5S2
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1
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| 1 |
IC50 = 110 nM
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CP0499014
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1-Allyl-1-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-3-(4-methoxy-benzyl)-urea
Show/Hide
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C32H39N3O2
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1
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| 1 |
IC50 = 110 nM
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CP0508596
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N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-ethyl-2-(4-nitrophenyl)acetamide
Show/Hide
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C30H35N3O3
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1
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| 1 |
IC50 = 110 nM
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CP0535783
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Allyl-{1-[3-phenyl-4-(5-phenyl-tetrazol-2-yl)-butyl]-piperidin-4-yl}-carbamic acid 4-nitro-benzyl ester
Show/Hide
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C33H37N7O4
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1
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| 1 |
IC50 = 111 nM
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CP0062872
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Allyl-[1-(4-benzoimidazol-1-yl-3-methyl-3-phenyl-butyl)-piperidin-4-yl]-carbamic acid benzyl ester
Show/Hide
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C34H40N4O2
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1
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| 1 |
IC50 = 112 nM
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CP0090925
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2,1,3-benzoxadiazol-5-ylmethyl N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-prop-2-enylcarbamate
Show/Hide
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C33H41N5O5
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1
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| 1 |
IC50 = 113.6 nM
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CP0413837
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N-[3-[4-[3-cyclohexyl-5-(6-methylpyridin-2-yl)-2-oxoimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
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C31H45N7O2
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1
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| 1 |
IC50 = 117.1 nM
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CP0037297
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1'-[3-(3,4-dichlorophenyl)-4-methyl(2-thienyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1,1-dioxide-3,4'-(hexahydropyridine)]
Show/Hide
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C27H30Cl2N2O4S3
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1
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| 1 |
IC50 = 120 nM
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CP0431458
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1'-[3-(3,4-dichlorophenyl)-4-methyl(3-quinolyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
Show/Hide
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C32H33Cl2N3O3S2
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1
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| 1 |
IC50 = 120 nM
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CP0370159
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N-[(2S)-2-(3-chlorophenyl)-4-[4-[3-(trifluoromethyl)phenyl]piperidin-1-yl]butyl]-N-methylbenzenesulfonamide
Show/Hide
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C29H32ClF3N2O2S
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1
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| 1 |
IC50 = 120 nM
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CP0461018
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N-[1-[(3R)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-ethylacetamide
Show/Hide
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C26H37N3O3S
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1
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| 1 |
IC50 = 120 nM
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CP0503044
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1-[1-[4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-1-ethyl-3-methylurea
Show/Hide
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C26H38N4O3S
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1
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| 1 |
IC50 = 120 nM
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CP0651202
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1-butyl-3-cyclohexylmethyl-9-(4-methoxyphenylmethyl)-1,4,9-triazaspiro[5.5]undeca-2,5-dione hydrochloride
Show/Hide
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C27H42ClN3O3
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1
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| 1 |
IC50 = 120 nM
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CP0514003
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1,3-benzodioxol-5-ylmethyl N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-prop-2-enylcarbamate
Show/Hide
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C34H43N3O6
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1
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| 1 |
IC50 = 122 nM
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CP0421097
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1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-[2-(4-chlorophenyl)ethyl]-N-ethylpiperidine-4-carboxamide
Show/Hide
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C33H44Cl2N4O3
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1
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| 1 |
IC50 = 125.81 nM
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CP0496162
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N-ethyl-N-[1-[3-(1-methylpiperidin-4-yl)-3-phenylpropyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C31H45N3O3S
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1
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| 1 |
IC50 = 126 nM
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CP0378315
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(2,4-Dimethyl-1-oxy-pyridin-3-yl)-(4-diphenylamino-[1,4']bipiperidinyl-1'-yl)-methanone
Show/Hide
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C30H36N4O2
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1
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| 1 |
IC50 = 127 nM
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CP0522780
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2-methyl-1-(8-(2-(4-phenyl-1-(1H-tetrazol-5-yl)piperidin-4-yl)ethyl)-8-azabicyclo[3.2.1]octan-3-yl)-1H-benzo[d]imidazole
Show/Hide
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C29H36N8
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1
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| 1 |
IC50 = 129 nM
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CP0376321
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1'-[3-(3,4-dichlorophenyl)-4-ethyl(phenyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
Show/Hide
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C30H34Cl2N2O3S2
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1
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| 1 |
IC50 = 130 nM
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CP0502564
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N-[4-[3-[4-[ethyl-[2-(4-methylsulfonylphenyl)acetyl]amino]piperidin-1-yl]-1-phenylpropyl]phenyl]benzamide
Show/Hide
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C38H43N3O4S
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1
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| 1 |
IC50 = 130 nM
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CP0869817
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(S)-1-butyl-3-(cyclohexylmethyl)-9-(3-(4-methoxyphenoxy)phenethyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C34H48ClN3O4
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1
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| 1 |
IC50 = 130 nM
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CP0919408
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(3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(4-methoxyphenoxy)benzyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C33H46ClN3O4
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1
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| 1 |
IC50 = 130 nM
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CP0522278
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(S)-N-ethyl-N-(1-(3-(4-methoxyphenyl)-3-(4-(methylsulfonyl)phenyl)propyl)piperidin-4-yl)-2-(4-(methylsulfonyl)phenyl)acetamide
Show/Hide
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C33H42N2O6S2
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1
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| 1 |
IC50 = 132 nM
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CP0379622
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(4R)-1-cyclohexyl-3-[1-[(4-phenoxyphenyl)methyl]piperidin-4-yl]-4-phenylimidazolidin-2-one
Show/Hide
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C33H39N3O2
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1
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| 1 |
IC50 = 135.9 nM
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CP0460802
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(3-Methoxy-phenyl)-[(3S,4S)-3-phenyl-4-(4-phenyl-piperidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone
Show/Hide
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C30H34N2O2
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1
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| 1 |
IC50 = 140 nM
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CP0565865
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(2-Methoxy-phenyl)-[(3S,4S)-3-phenyl-4-(4-phenyl-piperidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone
Show/Hide
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C30H34N2O2
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1
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| 1 |
IC50 = 140 nM
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CP0540331
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4-({[1'-(2,4-Dimethyl-1-oxy-pyridine-3-carbonyl)-4'-methyl-[1,4']bipiperidinyl-4-yl]-phenyl-amino}-methyl)-benzonitrile
Show/Hide
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C33H39N5O2
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1
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| 1 |
IC50 = 140 nM
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CP0511694
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8-[3-[3-(3,4-dichlorophenyl)-1-(furan-2-carbonyl)pyrrolidin-3-yl]propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
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C31H34Cl2N4O3
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1
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| 1 |
IC50 = 141.25 nM
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CP0507122
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3-benzyl-4-butyl-8-(1-(2,6-dimethylbenzoyl)piperidin-4-yl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Show/Hide
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C32H43N3O3
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1
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| 1 |
IC50 = 144 nM
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CP0520985
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N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl]methyl]piperidin-4-yl]-N-prop-2-enyl-2-[4-(trifluoromethyl)phenyl]acetamide
Show/Hide
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C34H42F3N3O3
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1
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| 1 |
IC50 = 149.2 nM
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CP0316023
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1'-[3-(3,4-dichlorophenyl)-4-methyl(3-nitrophenyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1,1-dioxide-3,4'-(hexahydropyridine)]
Show/Hide
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C29H31Cl2N3O6S2
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1
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| 1 |
IC50 = 150 nM
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CP0502397
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1-[(3S,4S)-1-Benzyl-4-(3-fluoro-phenyl)-pyrrolidin-3-ylmethyl]-4-phenyl-piperidine
Show/Hide
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C29H33FN2
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1
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| 1 |
IC50 = 150 nM
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CP0075158
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methyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-methylcarbamate
Show/Hide
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C25H35N3O4S
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1
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| 1 |
IC50 = 150 nM
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CP0509804
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N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-methyl-2-(4-nitrophenyl)acetamide
Show/Hide
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C29H33N3O3
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1
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| 1 |
IC50 = 150 nM
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CP0484604
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1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-ethyl-N-[2-(4-fluorophenyl)ethyl]piperidine-4-carboxamide
Show/Hide
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C33H44ClFN4O3
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1
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| 1 |
IC50 = 151.8 nM
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CP0461345
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1-((3S,4S)-1-Benzenesulfonyl-4-phenyl-pyrrolidin-3-ylmethyl)-4-phenyl-piperidine
Show/Hide
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C28H32N2O2S
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1
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| 1 |
IC50 = 152 nM
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CP0468134
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2-Phenyl-1-[(3S,4S)-3-phenyl-4-(4-phenyl-piperidin-1-ylmethyl)-pyrrolidin-1-yl]-ethanone
Show/Hide
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C30H34N2O
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1
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| 1 |
IC50 = 155 nM
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CP0392152
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1'-[3-(3,4-dichlorophenyl)-4-ethyl(phenyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1,1-dioxide-3,4'-(hexahydropyridine)]
Show/Hide
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C30H34Cl2N2O4S2
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1
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| 1 |
IC50 = 160 nM
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CP0919570
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rac-1-Butyl-3-(cyclohexylmethyl)-9-[(2-phenyl-1H-imidazol-4-yl)methyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione dihydrochloride
Show/Hide
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C29H43Cl2N5O2
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1
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| 1 |
IC50 = 160 nM
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CP0509425
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N-[1-[3-(4-benzylpiperidin-1-yl)-3-phenylpropyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C37H49N3O3S
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1
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| 1 |
IC50 = 162 nM
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CP0523188
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1-acetyl-N-(3-chloro-4-methylphenyl)-N-[3-[4-(4-cyanophenyl)-2-methylpiperazin-1-yl]propyl]piperidine-4-carboxamide
Show/Hide
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C30H38ClN5O2
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1
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| 1 |
IC50 = 163.8 nM
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CP0651200
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9-(1,4-benzodioxane-6-yl)-1-butyl-3-(2-methylpropyl)-1,4,9-triazaspiro[5.5]undeca-2,5-dione hydrochloride
Show/Hide
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C25H38ClN3O4
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2
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| 1 |
IC50 = 170 nM
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| 2 |
IC50 = 180 nM
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CP0917660
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(S)-3-benzyl-1-butyl-9-(3-(phenylthio)phenethyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C33H46ClN3O2S
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1
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| 1 |
IC50 = 170 nM
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CP0925515
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(3S)-1-Butyl-3-(cyclohexylmethyl)-9-[4-(phenylsulfanyl)benzyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C32H44ClN3O2S
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1
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| 1 |
IC50 = 170 nM
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CP0316022
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1'-[3-(3-chlorophenyl)-4-methyl(phenyl)sulfonamidobutyl]spiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]
Show/Hide
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C30H35ClN2O2S
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1
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| 1 |
IC50 = 180 nM
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CP0392399
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N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-2-(4-nitrophenyl)-N-prop-2-enylacetamide
Show/Hide
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C31H35N3O3
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1
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| 1 |
IC50 = 180 nM
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CP0440268
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1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-3-(4-fluoro-phenyl)-1-methyl-urea
Show/Hide
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C28H32FN3O
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1
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| 1 |
IC50 = 190 nM
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CP0387344
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1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-[2-(4-fluorophenyl)ethyl]piperidine-4-carboxamide
Show/Hide
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C31H40ClFN4O3
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1
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| 1 |
IC50 = 196.9 nM
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CP0379623
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(4R)-3-[1-(3H-benzimidazol-5-ylmethyl)piperidin-4-yl]-1-cyclohexyl-4-phenylimidazolidin-2-one
Show/Hide
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C28H35N5O
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1
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| 1 |
IC50 = 199.7 nM
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CP0535268
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1-((3S,4S)-1-Phenethyl-4-phenyl-pyrrolidin-3-ylmethyl)-4-phenyl-piperidine
Show/Hide
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C30H36N2
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1
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| 1 |
IC50 = 200 nM
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CP0932686
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5-benzyl-3-{2-(3-chlorophenyl)-4-[3-oxospiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]-1-yl]butyl}-(5R)-tetrahydro-1H-2,4-imidazoledione
Show/Hide
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C33H34ClN3O3
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1
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| 1 |
IC50 = 200 nM
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CP0444099
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N-[(2S)-2-(3-chlorophenyl)-4-[4-(4-chlorophenyl)piperidin-1-yl]butyl]-N-methylbenzenesulfonamide
Show/Hide
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C28H32Cl2N2O2S
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1
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| 1 |
IC50 = 200 nM
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CP0509700
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(R)-3-Cyclobutyl-2-[(3S,4S)-3-(4-imidazo[1,2-a]pyrimidin-2-yl-piperidin-1-ylmethyl)-4-phenyl-pyrrolidin-1-yl]-propionic acid
Show/Hide
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C29H37N5O2
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1
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| 1 |
IC50 = 200 nM
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CP0480361
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N-[1-[3-(4-aminophenyl)-3-phenylpropyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C31H39N3O3S
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1
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| 1 |
IC50 = 200 nM
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CP0514285
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N-ethyl-N-[1-[3-[4-[(2-methylpropan-2-yl)oxyamino]phenyl]-3-phenylpropyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C35H47N3O4S
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1
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| 1 |
IC50 = 200 nM
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CP0443489
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1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-ethyl-N-[(4-methylphenyl)methyl]piperidine-4-carboxamide
Show/Hide
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C33H45ClN4O3
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1
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| 1 |
IC50 = 202.43 nM
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CP0387047
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N-(3-chloro-4-methylphenyl)-4-fluoro-N-[3-[4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]propyl]benzamide
Show/Hide
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C29H32ClF2N3O
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1
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| 1 |
IC50 = 204.1 nM
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CP0375304
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(4R)-1-cyclohexyl-4-phenyl-3-[1-[(4-pyridin-3-ylphenyl)methyl]piperidin-4-yl]imidazolidin-2-one
Show/Hide
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C32H38N4O
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1
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| 1 |
IC50 = 214 nM
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CP0530519
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1-[(3S,4S)-1-Benzyl-4-(3-thiophen-3-yl-phenyl)-pyrrolidin-3-ylmethyl]-4-phenyl-piperidine
Show/Hide
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C33H36N2S
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1
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| 1 |
IC50 = 220 nM
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CP0236506
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4-fluorobenzyl allyl(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-yl)carbamate
Show/Hide
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C33H42FN3O4
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1
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| 1 |
IC50 = 220.6 nM
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CP0431306
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N-[1-[3-(4-acetylpiperazin-1-yl)-3-phenylpropyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
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C31H44N4O4S
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1
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| 1 |
IC50 = 229 nM
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CP0535682
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1'-[3-(3,4-dichlorophenyl)-4-phenylsulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
Show/Hide
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C28H30Cl2N2O3S2
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1
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| 1 |
IC50 = 230 nM
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CP0445029
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1-acetyl-N-(3-chloro-4-methylphenyl)-N-[3-[4-(4-cyanophenyl)piperazin-1-yl]propyl]piperidine-4-carboxamide
Show/Hide
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C29H36ClN5O2
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1
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| 1 |
IC50 = 239.5 nM
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CP0420023
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1-Allyl-1-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-3-(3-methyl-benzyl)-urea
Show/Hide
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C32H39N3O
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1
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| 1 |
IC50 = 240 nM
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CP0155164
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Allyl-{1-[4-(2-ethyl-benzoimidazol-1-yl)-3-phenyl-butyl]-piperidin-4-yl}-carbamic acid benzyl ester
Show/Hide
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C35H42N4O2
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1
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| 1 |
IC50 = 246 nM
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CP0959404
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(R)-5-Benzyl-3-[2-(3-chloro-phenyl)-4-(4-phenyl-piperidin-1-yl)-butyl]-imidazolidine-2,4-dione
Show/Hide
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C31H34ClN3O2
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1
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| 1 |
IC50 = 250 nM
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CP0375238
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N-[(2S)-4-(4-benzylpiperidin-1-yl)-2-(3-chlorophenyl)butyl]-N-methylbenzenesulfonamide
Show/Hide
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C29H35ClN2O2S
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1
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| 1 |
IC50 = 250 nM
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CP0927946
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endo-N-((S)-1-(4-(Trifluoromethyl)phenyl)-3-(3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-aza-bicyclo[3.2.1]octan-8-yl)propyl)-2-phenoxyacetamide
Show/Hide
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C31H38F3N5O2
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1
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| 1 |
IC50 = 253 nM
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CP0453370
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1-((3S,4S)-1-Benzyl-4-phenyl-pyrrolidin-3-ylmethyl)-4-phenyl-piperidine
Show/Hide
|
C29H34N2
|
1
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| 1 |
IC50 = 255 nM
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CP0504456
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1-acetyl-N-(3-chloro-4-methylphenyl)-N-[3-[4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]propyl]piperidine-3-carboxamide
Show/Hide
|
C30H40ClFN4O2
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1
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| 1 |
IC50 = 259.7 nM
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CP0457305
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[(3S,4S)-3-phenyl-4-[(4-phenylpiperidin-1-yl)methyl]pyrrolidin-1-yl]-pyridin-3-ylmethanone
Show/Hide
|
C28H31N3O
|
1
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| 1 |
IC50 = 260 nM
|
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CP0244679
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1'-[3-(3-chlorophenyl)-4-methyl(phenyl)sulfonamidobutyl]spiro[2,3-dihydrobenzo[b]furan-2,4'-(hexahydropyridine)]
Show/Hide
|
C29H33ClN2O3S
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1
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| 1 |
IC50 = 260 nM
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CP0436201
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4-[3-(4-{Ethyl-[2-(4-methanesulfonyl-phenyl)-acetyl]-amino}-piperidin-1-yl)-1-phenyl-propyl]-benzamide
Show/Hide
|
C32H39N3O4S
|
1
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| 1 |
IC50 = 260 nM
|
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CP0519738
|
4-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-azabicyclo[3.2.1]octan-8-yl)ethyl)-4-phenyl-N-(4-(trifluoromethyl)phenyl)piperidine-1-carboxamide
Show/Hide
|
C36H40F3N5O
|
1
|
| 1 |
IC50 = 265 nM
|
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CP0037286
|
1'-[3-(3-chlorophenyl)-4-methyl(phenyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-3,4'-(hexahydropyridine)]
Show/Hide
|
C29H33ClN2O2S2
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0649585
|
1-butyl-3-(2-methylpropyl)-9-(6-phenylhexyl)-1,4,9-triazaspiro-[5.5]undeca-2,5-dione hydrochloride
Show/Hide
|
C28H46ClN3O2
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0662025
|
(3R)-3-cyclohexylmethyl-9-(6-phenylhexyl)-1-propyl-1,4,9-triazaspiro[5.5]undeca-2,5-dione hydrochloride
Show/Hide
|
C30H48ClN3O2
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0467624
|
(4R)-1-cyclohexyl-3-[1-[[4-(2-methyltetrazol-5-yl)phenyl]methyl]piperidin-4-yl]-4-phenylimidazolidin-2-one
Show/Hide
|
C29H37N7O
|
1
|
| 1 |
IC50 = 279.5 nM
|
|
|
|
CP0377952
|
(4-Diphenylamino-4'-methyl-[1,4']bipiperidinyl-1'-yl)-(1H-indol-3-yl)-methanone
Show/Hide
|
C32H36N4O
|
1
|
| 1 |
IC50 = 283 nM
|
|
|
|
CP0518196
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-methyl-2-[4-(trifluoromethoxy)phenyl]acetamide
Show/Hide
|
C30H33F3N2O2
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0662079
|
(3S)-3-cyclohexylmethyl-9-(6-phenylhexyl)-1-propyl-1,4,9-triazaspiro[5.5]undeca-2,5-dione hydrochloride
Show/Hide
|
C30H48ClN3O2
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0513964
|
3-(cyclohexylmethyl)-8-(1-(2,6-dimethylbenzoyl)piperidin-4-yl)-4-propyl-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Show/Hide
|
C31H47N3O3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0918696
|
rac-1-Benzyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
|
C32H38ClN3O3
|
1
|
| 1 |
IC50 = 300 nM
|
|
|
|
CP0404846
|
N-ethyl-N-[1-[3-(4-fluorophenyl)-3-phenylpropyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C31H37FN2O3S
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0440266
|
N-cyclopropyl-N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-2-(4-nitrophenyl)acetamide
Show/Hide
|
C31H35N3O3
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0499252
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-ethyl-2-[4-(trifluoromethoxy)phenyl]acetamide
Show/Hide
|
C31H35F3N2O2
|
1
|
| 1 |
IC50 = 310 nM
|
|
|
|
CP0493055
|
4-nitrobenzyl allyl(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-(3-methoxyphenyl)pyrrolidin-3-yl)methyl)piperidin-4-yl)carbamate
Show/Hide
|
C34H44N4O7
|
1
|
| 1 |
IC50 = 318 nM
|
|
|
|
CP0397976
|
1-acetyl-N-[3-[4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]propyl]-N-phenylpiperidine-4-carboxamide
Show/Hide
|
C29H39FN4O2
|
1
|
| 1 |
IC50 = 319.9 nM
|
|
|
|
CP0515813
|
1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-1-ethyl-3-p-tolyl-urea
Show/Hide
|
C30H37N3O
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0462257
|
2-methyl-1-(8-(2-(4-phenyl-1-(pyrimidin-2-yl)piperidin-4-yl)ethyl)-8-azabicyclo[3.2.1]octan-3-yl)-1H-benzo[d]imidazole
Show/Hide
|
C32H38N6
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0919569
|
rac-1-Butyl-3-(methoxymethyl)-9-(4-phenoxybenzyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
|
C24H30ClN3O4
|
1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0481239
|
1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-ethyl-N-[(4-fluorophenyl)methyl]piperidine-4-carboxamide
Show/Hide
|
C32H42ClFN4O3
|
1
|
| 1 |
IC50 = 320.33 nM
|
|
|
|
CP0920372
|
rac-1,3-Diisobutyl-9-(4-phenoxybenzyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
|
C29H40ClN3O3
|
1
|
| 1 |
IC50 = 330 nM
|
|
|
|
CP0521219
|
Allyl-{1-[3-phenyl-4-(5-phenyl-tetrazol-1-yl)-butyl]-piperidin-4-yl}-carbamic acid 4-nitro-benzyl ester
Show/Hide
|
C33H37N7O4
|
1
|
| 1 |
IC50 = 335 nM
|
|
|
|
CP0413841
|
(4R)-1-cyclohexyl-3-[1-[(4-morpholin-4-ylphenyl)methyl]piperidin-4-yl]-4-phenylimidazolidin-2-one
Show/Hide
|
C31H42N4O2
|
1
|
| 1 |
IC50 = 336.2 nM
|
|
|
|
CP0431307
|
N-ethyl-N-[1-[3-(4-methylpiperidin-1-yl)-3-phenylpropyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C31H45N3O3S
|
1
|
| 1 |
IC50 = 339 nM
|
|
|
|
CP0037295
|
1'-[3-(3,4-dichlorophenyl)-4-methyl(dimethylamino)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
Show/Hide
|
C25H33Cl2N3O3S2
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0437694
|
1'-[3-(3,4-dichlorophenyl)-4-methyl(1-methyl-imidazol-4-yl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
Show/Hide
|
C27H32Cl2N4O3S2
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0411656
|
N-[3-[4-[3-cyclohexyl-5-(2-fluorophenyl)-2-oxoimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
|
C31H43FN6O2
|
1
|
| 1 |
IC50 = 342 nM
|
|
|
|
CP0379620
|
methyl 3-[1-cyclohexyl-3-[1-[4-[(4,6-dimethylpyrimidine-5-carbonyl)amino]butan-2-yl]piperidin-4-yl]-2-oxoimidazolidin-4-yl]benzoate
Show/Hide
|
C33H46N6O4
|
1
|
| 1 |
IC50 = 346.5 nM
|
|
|
|
CP0430219
|
N-methyl-N-[(2S)-4-[4-[(4R,5R)-4-methyl-2-oxo-5-phenyl-1,3-oxazolidin-3-yl]piperidin-1-yl]-2-phenylbutyl]benzenesulfonamide
Show/Hide
|
C32H39N3O4S
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0509812
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-prop-2-enyl-2-[4-(trifluoromethoxy)phenyl]acetamide
Show/Hide
|
C32H35F3N2O2
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0319095
|
1'-[3-(3,4-dichlorophenyl)-4-methyl(1-naphthyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
Show/Hide
|
C33H34Cl2N2O3S2
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0400750
|
N-ethyl-N-[1-[3-(4-methylpiperazin-1-yl)-3-phenylpropyl]piperidin-4-yl]-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C30H44N4O3S
|
1
|
| 1 |
IC50 = 363 nM
|
|
|
|
CP0499165
|
3-(3,4-Dichloro-phenyl)-1-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-1-methyl-urea
Show/Hide
|
C28H31Cl2N3O
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0501150
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-methyl-2-[4-(trifluoromethyl)phenyl]acetamide
Show/Hide
|
C30H33F3N2O
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0501169
|
1-((3S,4S)-1-Benzyl-4-m-tolyl-pyrrolidin-3-ylmethyl)-4-phenyl-piperidine
Show/Hide
|
C30H36N2
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0157024
|
N-[(2S)-2-(3-chlorophenyl)-4-[4-(2-methylphenyl)piperidin-1-yl]butyl]-N-methylbenzenesulfonamide
Show/Hide
|
C29H35ClN2O2S
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0413842
|
(4R)-1-cyclohexyl-4-phenyl-3-[1-[(4-phenylphenyl)methyl]piperidin-4-yl]imidazolidin-2-one
Show/Hide
|
C33H39N3O
|
1
|
| 1 |
IC50 = 435.9 nM
|
|
|
|
CP0486841
|
8-[3-[1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
|
C34H38Cl2N4O2
|
1
|
| 1 |
IC50 = 446.68 nM
|
|
|
|
CP0925514
|
(3S)-1-Butyl-3-(cyclohexylmethyl)-9-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
|
C30H43ClN4O3
|
1
|
| 1 |
IC50 = 450 nM
|
|
|
|
CP0376583
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-2-(4-hydroxyphenyl)-N-methylacetamide
Show/Hide
|
C29H34N2O2
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0754045
|
4-(4-(((S)-1-butyl-3-((R)-cyclohexyl(hydroxy)methyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl)methyl)phenoxy)benzoic acid hydrochloride
Show/Hide
|
C33H44ClN3O6
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0421099
|
1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-[(4-cyanophenyl)methyl]-N-ethylpiperidine-4-carboxamide
Show/Hide
|
C33H42ClN5O3
|
1
|
| 1 |
IC50 = 473.33 nM
|
|
|
|
CP0402182
|
4-Phenyl-1-[(3S,4S)-4-phenyl-1-(1-phenyl-ethyl)-pyrrolidin-3-ylmethyl]-piperidine
Show/Hide
|
C30H36N2
|
1
|
| 1 |
IC50 = 480 nM
|
|
|
|
CP0436258
|
(R)-N-(1-(3-(3-tert-butylphenyl)-3-(4-(methylsulfonyl)phenyl)propyl)piperidin-4-yl)-N-ethyl-2-(4-(methylsulfonyl)phenyl)acetamide
Show/Hide
|
C36H48N2O5S2
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0699196
|
3-(2-methylpropyl)-9-(4-phenoxyphenylmethyl)-1-propyl-1,4,9-triazaspiro[5.5]undeca-2,5-dione hydrochloride
Show/Hide
|
C28H38ClN3O3
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0423059
|
(4-Diphenylamino-4'-methyl-[1,4']bipiperidinyl-1'-yl)-phenyl-methanone
Show/Hide
|
C30H35N3O
|
1
|
| 1 |
IC50 = 511 nM
|
|
|
|
CP0421100
|
1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-benzyl-N-ethylpiperidine-4-carboxamide
Show/Hide
|
C32H43ClN4O3
|
1
|
| 1 |
IC50 = 525 nM
|
|
|
|
CP0379586
|
(4R)-1-cyclohexyl-4-phenyl-3-[1-[(4-pyridin-4-ylphenyl)methyl]piperidin-4-yl]imidazolidin-2-one
Show/Hide
|
C32H38N4O
|
1
|
| 1 |
IC50 = 548 nM
|
|
|
|
CP0526294
|
(R)-N-(1-(3-(2,6-difluorophenyl)-3-(4-(methylsulfonyl)phenyl)propyl)piperidin-4-yl)-N-ethyl-2-(4-(methylsulfonyl)phenyl)acetamide
Show/Hide
|
C32H38F2N2O5S2
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
|
CP0486416
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-methyl-2-(4-methylsulfanylphenyl)acetamide
Show/Hide
|
C30H36N2OS
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
|
CP0920374
|
rac-1-Butyl-3-(cyclohexylmethyl)-9-[(2-phenyl-1,3-thiazol-4-yl)methyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
|
C29H41ClN4O2S
|
1
|
| 1 |
IC50 = 570 nM
|
|
|
|
CP0499171
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-2-(4-methoxyphenyl)-N-methylacetamide
Show/Hide
|
C30H36N2O2
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0505435
|
2-(4-Bromo-phenyl)-N-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-N-methyl-acetamide
Show/Hide
|
C29H33BrN2O
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0448300
|
cyclohexyl-[4-methyl-4-[4-(N-phenylanilino)piperidin-1-yl]piperidin-1-yl]methanone
Show/Hide
|
C30H41N3O
|
1
|
| 1 |
IC50 = 580 nM
|
|
|
|
CP0437046
|
N-[(2S)-2-(3,4-dichlorophenyl)-4-(1-oxospiro[2H-1-benzothiophene-3,4'-piperidine]-1'-yl)butyl]-N-methyl-1-phenylmethanesulfonamide
Show/Hide
|
C30H34Cl2N2O3S2
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
|
CP0913190
|
rac-Benzyl [1-butyl-2,5-dioxo-9-(4-phenoxybenzyl)-1,4,9-triazaspiro[5.5]undec-3-yl]acetate hydrochloride
Show/Hide
|
C34H40ClN3O5
|
1
|
| 1 |
IC50 = 590 nM
|
|
|
|
CP0910212
|
3-{2-(3-chlorophenyl)-4-[3-oxospiro[2,3-dihydro-1H-indene-1,4'-(hexahydropyridine)]-1-yl]butyl}-5-phenyl-(5R)-tetrahydro-1H-2,4-imidazoledione
Show/Hide
|
C32H32ClN3O3
|
1
|
| 1 |
IC50 = 606 nM
|
|
|
|
CP0555292
|
(3S,4S)-3-Phenyl-4-(4-phenyl-piperidin-1-ylmethyl)-pyrrolidine-1-carboxylic acid phenylamide
Show/Hide
|
C29H33N3O
|
1
|
| 1 |
IC50 = 610 nM
|
|
|
|
CP0497351
|
4-({[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-methyl-carbamoyl}-methyl)-benzoic acid methyl ester
Show/Hide
|
C31H36N2O3
|
1
|
| 1 |
IC50 = 630 nM
|
|
|
|
CP0383297
|
1-oxo-1N-[2-(3,4-dichlorophenyl)-4-spiro[2,3-dihydrobenzo[b]thiophene-3,4'-(hexahydropyridine)]-1-yl-(2S)-butyl]-1N-methyl-2-phenylacetamide
Show/Hide
|
C31H34Cl2N2O2S
|
1
|
| 1 |
IC50 = 640 nM
|
|
|
|
CP0464507
|
2-(3,4-Dimethoxy-phenyl)-N-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-N-methyl-acetamide
Show/Hide
|
C31H38N2O3
|
1
|
| 1 |
IC50 = 650 nM
|
|
|
|
CP0497015
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-2-(4-fluorophenyl)-N-methylacetamide
Show/Hide
|
C29H33FN2O
|
1
|
| 1 |
IC50 = 660 nM
|
|
|
|
CP0431351
|
2-(4-Acetylamino-phenyl)-N-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-N-methyl-acetamide
Show/Hide
|
C31H37N3O2
|
1
|
| 1 |
IC50 = 680 nM
|
|
|
|
CP0433541
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-2-(3-methoxyphenyl)-N-methylacetamide
Show/Hide
|
C30H36N2O2
|
1
|
| 1 |
IC50 = 680 nM
|
|
|
|
CP0497272
|
2-(3,4-Difluoro-phenyl)-N-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-N-methyl-acetamide
Show/Hide
|
C29H32F2N2O
|
1
|
| 1 |
IC50 = 690 nM
|
|
|
|
CP0346872
|
N-[(2S)-2-(3-chlorophenyl)-4-(4-phenylpiperazin-1-yl)butyl]-N-methylbenzenesulfonamide
Show/Hide
|
C27H32ClN3O2S
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0523076
|
N-(3,4-dichlorophenyl)-N-[3-[4-[(4-fluorobenzoyl)amino]piperidin-1-yl]propyl]-1-methylsulfonylpiperidine-4-carboxamide
Show/Hide
|
C28H35Cl2FN4O4S
|
1
|
| 1 |
IC50 = 730 nM
|
|
|
|
CP0518117
|
N-[1-[3-[4-(benzenesulfonamido)phenyl]-3-phenylpropyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C37H43N3O5S2
|
1
|
| 1 |
IC50 = 740 nM
|
|
|
|
CP0391470
|
(4-Chloro-phenyl)-[(3S,4S)-3-phenyl-4-(4-phenyl-piperidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone
Show/Hide
|
C29H31ClN2O
|
1
|
| 1 |
IC50 = 750 nM
|
|
|
|
CP0541569
|
N-[1-[3,3-bis(4-chlorophenyl)propyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C31H36Cl2N2O3S
|
1
|
| 1 |
IC50 = 760 nM
|
|
|
|
CP0928800
|
endo-tert-butyl 3-(3,4-dichlorophenyl)-3-(2-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-aza-bicyclo[3.2.1]octan-8-yl)ethyl)pyrrolidine-1-carboxylate
Show/Hide
|
C32H40Cl2N4O2
|
1
|
| 1 |
IC50 = 776.25 nM
|
|
|
|
CP0394289
|
1N-[2-(3,4-dichlorophenyl)-4-spiro[2,3-dihydrobenzo[b]thiophene-3,4'-(hexahydropyridine)]-1-yl-(2S)-butyl]-1-oxide-1N-methyl-phenylcarbamate
Show/Hide
|
C30H32Cl2N2O3S
|
1
|
| 1 |
IC50 = 780 nM
|
|
|
|
CP0483753
|
N-[1-[3,3-bis(4-fluorophenyl)propyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C31H36F2N2O3S
|
1
|
| 1 |
IC50 = 780 nM
|
|
|
|
CP0439028
|
2-(3,4-Dichloro-phenyl)-N-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-N-methyl-acetamide
Show/Hide
|
C29H32Cl2N2O
|
1
|
| 1 |
IC50 = 780 nM
|
|
|
|
CP0492413
|
N-ethyl-2-(4-methylsulfonylphenyl)-N-[1-[(3R)-3-(3-methylsulfonylphenyl)-3-(1-methylsulfonylpiperidin-4-yl)propyl]piperidin-4-yl]acetamide
Show/Hide
|
C32H47N3O7S3
|
1
|
| 1 |
IC50 = 794 nM
|
|
|
|
CP0463708
|
benzyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-N-(cyclohexylmethyl)carbamate
Show/Hide
|
C37H49N3O4S
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0497013
|
2-(4-Chloro-phenyl)-N-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-N-methyl-acetamide
Show/Hide
|
C29H33ClN2O
|
1
|
| 1 |
IC50 = 800 nM
|
|
|
|
CP0467541
|
1-[(3S,4S)-1-Benzyl-4-(3-chloro-phenyl)-pyrrolidin-3-ylmethyl]-4-phenyl-piperidine
Show/Hide
|
C29H33ClN2
|
1
|
| 1 |
IC50 = 810 nM
|
|
|
|
CP0502069
|
N-[(2S)-2-(3,4-dichlorophenyl)-4-(1-oxospiro[2H-1-benzothiophene-3,4'-piperidine]-1'-yl)butyl]-N-methylmethanesulfonamide
Show/Hide
|
C24H30Cl2N2O3S2
|
1
|
| 1 |
IC50 = 850 nM
|
|
|
|
CP0651215
|
9-benzyl-1-butyl-3-(2-methylpropyl)-1,4,9-triazaspiro[5.5]-undeca-2,5-dione hydrochloride
Show/Hide
|
C23H36ClN3O2
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0397975
|
1-acetyl-N-(3-chloro-4-methylphenyl)-N-[3-[4-[(4-fluorophenyl)methyl]-1,4-diazepan-1-yl]propyl]piperidine-4-carboxamide
Show/Hide
|
C30H40ClFN4O2
|
1
|
| 1 |
IC50 = 906 nM
|
|
|
|
CP0411652
|
N-[3-[4-(3-cyclohexyl-2-oxo-5-pyridin-2-ylimidazolidin-1-yl)piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
|
C30H43N7O2
|
1
|
| 1 |
IC50 = 908.8 nM
|
|
|
|
CP0503171
|
4-Phenyl-1-((3R,4S)-4-phenyl-pyrrolidin-3-ylmethyl)-piperidine
Show/Hide
|
C22H28N2
|
1
|
| 1 |
IC50 = 980 nM
|
|
|
|
CP0250706
|
1'-[3-(3,4-dichlorophenyl)-4-methyl(phenyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-3,4'-(hexahydropyridine)]
Show/Hide
|
C29H32Cl2N2O2S2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0523280
|
1N-benzyl-1N-methyl-2-(3,4-dichlorophenyl)-4-spiro[2,3-dihydrobenzo[b]thiophene-1,1-dioxide-3,4'-(hexahydropyridine)]-1-yl-(2S)-butan-1-amine
Show/Hide
|
C30H34Cl2N2O2S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0076424
|
1-[1-[4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]-3-methylurea
Show/Hide
|
C24H34N4O3S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0249044
|
tert-butyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]carbamate
Show/Hide
|
C27H39N3O4S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0555213
|
N-methyl-N-[(2S)-4-[4-(2-oxo-1,3-oxazolidin-3-yl)piperidin-1-yl]-2-phenylbutyl]benzenesulfonamide
Show/Hide
|
C25H33N3O4S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0426816
|
3-Cyclopropyl-2-((S)-3-(3-fluoro-phenyl)-4-{4-[2-((R)-hydroxy-phenyl-phosphinoyl)-ethyl]-piperidin-1-ylmethyl}-pyrrolidin-1-yl)-propionic acid
Show/Hide
|
C30H40FN2O4P
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0511277
|
8-[3-[1-benzyl-3-(3,4-dichlorophenyl)-6-oxopiperidin-3-yl]propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
|
C34H38Cl2N4O2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0494685
|
8-[3-[1-benzyl-3-(3,4-dichlorophenyl)-5-oxopyrrolidin-3-yl]propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
|
C33H36Cl2N4O2
|
1
|
| 1 |
IC50 = 1023.29 nM
|
|
|
|
CP0448876
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-methyl-2-(2,4,5-trimethoxyphenyl)acetamide
Show/Hide
|
C32H40N2O4
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0940313
|
exo-(4-{3-[3-(2-Methyl-benzoimidazol-1-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-propyl}-4-phenyl-piperidin-1-yl)-phenyl-methanone
Show/Hide
|
C36H42N4O
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0157026
|
1N-[2-(3,4-dichlorophenyl)-4-spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]-1-yl-(2S)-butyl]-1N-methyl-1-octanesulfonamide
Show/Hide
|
C31H44Cl2N2O3S2
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0497014
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-2-(3-fluorophenyl)-N-methylacetamide
Show/Hide
|
C29H33FN2O
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0375098
|
8-[2-[3-(3,4-dichlorophenyl)-1-(furan-2-carbonyl)pyrrolidin-3-yl]ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
|
C30H32Cl2N4O3
|
1
|
| 1 |
IC50 = 1479.11 nM
|
|
|
|
CP0186273
|
1-(1-{3-[1-Benzoyl-3-(3,4-dichloro-phenyl)-piperidin-3-yl]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one
Show/Hide
|
C33H36Cl2N4O2
|
1
|
| 1 |
IC50 = 1584.89 nM
|
|
|
|
CP0502218
|
1'-[3-(3,4-dichlorophenyl)-4-phenylsulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-3,4'-(hexahydropyridine)]
Show/Hide
|
C28H30Cl2N2O2S2
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0461086
|
(2,6-Dimethyl-phenyl)-[4'-methyl-4-(1-methyl-1H-indol-6-ylamino)-[1,4']bipiperidinyl-1'-yl]-methanone
Show/Hide
|
C29H38N4O
|
1
|
| 1 |
IC50 = 1680 nM
|
|
|
|
CP0449632
|
N-[3-[4-[3-cyclohexyl-5-(2-methylphenyl)-2-oxoimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
|
C32H46N6O2
|
1
|
| 1 |
IC50 = 1702 nM
|
|
|
|
CP0464631
|
3-Cyclohexyl-1-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-1-methyl-urea
Show/Hide
|
C28H39N3O
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0411626
|
N-[(3S)-3-[4-[(5S)-3-cyclohexyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
|
C31H44N6O2
|
1
|
| 1 |
IC50 = 1839 nM
|
|
|
|
CP0440244
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-2-(2-fluorophenyl)-N-methylacetamide
Show/Hide
|
C29H33FN2O
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0878092
|
(3S)-3-(2-methylpropyl)-9-(6-phenylhexyl)-1-propyl-1,4,9-triazaspiro[5.5]undeca-2,5-dione hydrochloride
Show/Hide
|
C27H44ClN3O2
|
1
|
| 1 |
IC50 = 2000 nM
|
|
|
|
CP0379621
|
(4R)-1-cyclohexyl-4-phenyl-3-[1-[(4-pyrimidin-2-ylphenyl)methyl]piperidin-4-yl]imidazolidin-2-one
Show/Hide
|
C31H37N5O
|
1
|
| 1 |
IC50 = 2040 nM
|
|
|
|
CP0522559
|
1-Allyl-1-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-3-phenyl-urea
Show/Hide
|
C30H35N3O
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0445030
|
N-(3-chloro-4-methylphenyl)-N-[3-[4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]propyl]acetamide
Show/Hide
|
C24H31ClFN3O
|
1
|
| 1 |
IC50 = 2158 nM
|
|
|
|
CP0448609
|
(2,6-Dimethyl-phenyl)-[4'-methyl-4-(1-methyl-1H-indol-7-ylamino)-[1,4']bipiperidinyl-1'-yl]-methanone
Show/Hide
|
C29H38N4O
|
1
|
| 1 |
IC50 = 2165 nM
|
|
|
|
CP0420121
|
2-(3-Chloro-phenyl)-N-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-N-methyl-acetamide
Show/Hide
|
C29H33ClN2O
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
|
CP0392539
|
2-Biphenyl-4-yl-N-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-N-methyl-acetamide
Show/Hide
|
C35H38N2O
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0526084
|
8-[2-[1-(benzenesulfonyl)-4-(3,4-dichlorophenyl)piperidin-4-yl]oxyethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
|
C32H36Cl2N4O4S
|
1
|
| 1 |
IC50 = 2398.83 nM
|
|
|
|
CP0346871
|
N-[(2S)-2-(3-chlorophenyl)-4-[4-(2-methylphenyl)piperazin-1-yl]butyl]-N-methylbenzenesulfonamide
Show/Hide
|
C28H34ClN3O2S
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0496869
|
2-(2,4-Dichloro-phenyl)-N-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-N-methyl-acetamide
Show/Hide
|
C29H32Cl2N2O
|
1
|
| 1 |
IC50 = 2600 nM
|
|
|
|
CP0495083
|
2-(3,5-Dimethoxy-phenyl)-N-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-N-methyl-acetamide
Show/Hide
|
C31H38N2O3
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0409008
|
N-[3-[4-(3-cyclohexyl-2-oxo-5-pyridin-3-ylimidazolidin-1-yl)piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
|
C30H43N7O2
|
1
|
| 1 |
IC50 = 2938 nM
|
|
|
|
CP0878091
|
(3R)-3-(2-methylpropyl)-9-(6-phenylhexyl)-1-propyl-1,4,9-triazaspiro[5.5]undeca-2,5-dione hydrochloride
Show/Hide
|
C27H44ClN3O2
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0918698
|
rac-Benzyl 1-butyl-3-(cyclohexylmethyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undecane-9-carboxylate hydrochloride
Show/Hide
|
C27H40ClN3O4
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0426747
|
N-[3-[4-[5-(4-bromophenyl)-3-cyclohexyl-2-oxoimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
|
C31H43BrN6O2
|
1
|
| 1 |
IC50 = 3020 nM
|
|
|
|
CP0395765
|
N-[3-[4-[5-(2-chlorophenyl)-3-cyclohexyl-2-oxoimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
|
C31H43ClN6O2
|
1
|
| 1 |
IC50 = 3148 nM
|
|
|
|
CP0856132
|
(3S)-1,9-dibenzyl-3-(2-methylpropyl)-1,4,9-triazaspiro[5.5]-undeca-2,5-dione hydrochloride
Show/Hide
|
C26H34ClN3O2
|
1
|
| 1 |
IC50 = 3200 nM
|
|
|
|
CP0497012
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N,3-dimethylbutanamide
Show/Hide
|
C26H36N2O
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0467687
|
8-[2-[4-(3,4-dichlorophenyl)-1-(furan-2-carbonyl)piperidin-4-yl]oxyethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
|
C31H34Cl2N4O4
|
1
|
| 1 |
IC50 = 3467.37 nM
|
|
|
|
CP0409030
|
1'-[4-phenyl-1-phenylsulfonyl-(3R,4S)-tetrahydro-1H-3-pyrrolylmethyl]spiro[2,3-dihydrobenzo[b]thiophene-3,4'-(hexahydropyridine)1-oxide]
Show/Hide
|
C29H32N2O3S2
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0525851
|
2-(4-Benzyloxy-phenyl)-N-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-N-methyl-acetamide
Show/Hide
|
C36H40N2O2
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0439027
|
2-(2-Chloro-phenyl)-N-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-N-methyl-acetamide
Show/Hide
|
C29H33ClN2O
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0431304
|
N-[1-[(3S)-3-(3,5-difluorophenyl)-3-(4-methylsulfonylpiperazin-1-yl)propyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide
Show/Hide
|
C30H42F2N4O5S2
|
1
|
| 1 |
IC50 = 3700 nM
|
|
|
|
CP0489985
|
tert-butyl 4-[3-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]-4-phenylpiperidine-1-carboxylate
Show/Hide
|
C31H42N4O3
|
1
|
| 1 |
IC50 = 3981.07 nM
|
|
|
|
CP0511279
|
8-[2-[3-(3,4-dichlorophenyl)-1-(furan-2-carbonyl)pyrrolidin-3-yl]oxyethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
|
C30H32Cl2N4O4
|
1
|
| 1 |
IC50 = 3981.07 nM
|
|
|
|
CP0379331
|
1-Oxo-1,3-dihydro-isoindole-2-carboxylic acid [1-(3,3-diphenyl-propyl)-piperidin-4-yl]-methyl-amide
Show/Hide
|
C30H33N3O2
|
1
|
| 1 |
IC50 = 4100 nM
|
|
|
|
CP0467688
|
tert-butyl 4-[2-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)ethyl]-4-phenylpiperidine-1-carboxylate
Show/Hide
|
C31H42N4O3
|
1
|
| 1 |
IC50 = 4570.88 nM
|
|
|
|
CP0486847
|
8-[2-[1-(cyclopentanecarbonyl)-3-(3,4-dichlorophenyl)pyrrolidin-3-yl]oxyethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
|
C31H38Cl2N4O3
|
1
|
| 1 |
IC50 = 4786.3 nM
|
|
|
|
CP0497051
|
3-(3-Cyano-phenyl)-1-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-1-methyl-urea
Show/Hide
|
C29H32N4O
|
1
|
| 1 |
IC50 = 4900 nM
|
|
|
|
CP0918940
|
exo-Furan-2-yl-(4-{3-[3-(2-methyl-benzoimidazol-1-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-propyl}-4-phenyl-piperidin-1-yl)-methanone
Show/Hide
|
C34H40N4O2
|
1
|
| 1 |
IC50 = 5011.87 nM
|
|
|
|
CP0392342
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-methyl-3-nitrobenzamide
Show/Hide
|
C28H31N3O3
|
1
|
| 1 |
IC50 = 5100 nM
|
|
|
|
CP0526082
|
8-[3-[3-(3,4-dichlorophenyl)-1-(furan-2-ylmethyl)pyrrolidin-3-yl]propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
|
C31H36Cl2N4O2
|
1
|
| 1 |
IC50 = 5248.07 nM
|
|
|
|
CP0408642
|
1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-1-ethyl-3-(1-phenyl-ethyl)-urea
Show/Hide
|
C31H39N3O
|
1
|
| 1 |
IC50 = 5400 nM
|
|
|
|
CP0404700
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N,3,3-trimethylbutanamide
Show/Hide
|
C27H38N2O
|
1
|
| 1 |
IC50 = 5500 nM
|
|
|
|
CP0408641
|
1-[1-(3,3-Diphenyl-propyl)-piperidin-4-yl]-1-methyl-3-m-tolyl-urea
Show/Hide
|
C29H35N3O
|
1
|
| 1 |
IC50 = 5900 nM
|
|
|
|
CP0509858
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-methyl-2-oxo-2-phenylacetamide
Show/Hide
|
C29H32N2O2
|
1
|
| 1 |
IC50 = 5900 nM
|
|
|
|
CP0491853
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-methylpyridine-4-carboxamide
Show/Hide
|
C27H31N3O
|
1
|
| 1 |
IC50 = 6100 nM
|
|
|
|
CP0565322
|
N-[3-[4-(4-cyanophenyl)piperazin-1-yl]-1-phenylpropyl]cyclohexanecarboxamide
Show/Hide
|
C27H34N4O
|
1
|
| 1 |
IC50 = 6290 nM
|
|
|
|
CP0420120
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-methyl-2-phenylpropanamide
Show/Hide
|
C30H36N2O
|
1
|
| 1 |
IC50 = 6800 nM
|
|
|
|
CP0511695
|
8-[3-[3-(3,4-dichlorophenyl)-1-(furan-2-carbonyl)pyrrolidin-3-yl]propyl]-3-methyl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
|
C32H36Cl2N4O3
|
1
|
| 1 |
IC50 = 7079.46 nM
|
|
|
|
CP0420119
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-4-fluoro-N-methylbenzamide
Show/Hide
|
C28H31FN2O
|
1
|
| 1 |
IC50 = 7200 nM
|
|
|
|
CP0499028
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-methylcyclobutanecarboxamide
Show/Hide
|
C26H34N2O
|
1
|
| 1 |
IC50 = 7400 nM
|
|
|
|
CP0850182
|
(3R)-1,9-dibenzyl-3-(2-methylpropyl)-1,4,9-triazaspiro[5.5]-undeca-2,5-dione hydrochloride
Show/Hide
|
C26H34ClN3O2
|
1
|
| 1 |
IC50 = 7600 nM
|
|
|
|
CP0404699
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-methylfuran-2-carboxamide
Show/Hide
|
C26H30N2O2
|
1
|
| 1 |
IC50 = 7900 nM
|
|
|
|
CP0500938
|
tert-butyl 4-(3,4-dichlorophenyl)-4-[3-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]propyl]piperidine-1-carboxylate
Show/Hide
|
C31H40Cl2N4O3
|
1
|
| 1 |
IC50 = 7943.28 nM
|
|
|
|
CP0462378
|
tert-butyl 4-[3-(4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-8-yl)propyl]-4-phenylpiperidine-1-carboxylate
Show/Hide
|
C32H44N4O3
|
1
|
| 1 |
IC50 = 8511.38 nM
|
|
|
|
CP0509857
|
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-N-methylthiophene-2-carboxamide
Show/Hide
|
C26H30N2OS
|
1
|
| 1 |
IC50 = 8700 nM
|
|
|
|
CP0411627
|
N-[(3R)-3-[4-[(5S)-3-cyclohexyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]butyl]-4,6-dimethylpyrimidine-5-carboxamide
Show/Hide
|
C31H44N6O2
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1
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| 1 |
IC50 = 9039 nM
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CP0517420
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8-[3-[1-(benzenesulfonyl)-3-(3,4-dichlorophenyl)azetidin-3-yl]propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
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C31H34Cl2N4O3S
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1
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| 1 |
IC50 = 9120.11 nM
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CP0424022
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8-[2-[1-(furan-2-carbonyl)-3-phenylpyrrolidin-3-yl]ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
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C30H34N4O3
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1
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| 1 |
IC50 = 9332.54 nM
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CP0494686
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8-[2-[1-benzyl-3-(3,4-dichlorophenyl)-5-oxopyrrolidin-3-yl]ethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
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C32H34Cl2N4O2
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1
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| 1 |
IC50 = 9332.54 nM
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CP0401668
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1'-[3-(3,4-dichlorophenyl)-4-ethyl(phenyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-3,4'-(hexahydropyridine)]
Show/Hide
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C30H34Cl2N2O2S2
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1
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| 1 |
IC50 = 10000 nM
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CP0408953
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N-[(2S)-2-(3-chlorophenyl)-4-[methyl(2-phenylethyl)amino]butyl]-N-methylbenzenesulfonamide
Show/Hide
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C26H31ClN2O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0444108
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N-[(2S)-2-(3,4-dichlorophenyl)-4-(5-phenylpyridin-2-yl)butyl]-N-methylbenzenesulfonamide
Show/Hide
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C28H26Cl2N2O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0502456
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N-[(2S)-2-(3,4-dichlorophenyl)-4-(4-phenylphenyl)butyl]-N-methylbenzenesulfonamide
Show/Hide
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C29H27Cl2NO2S
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1
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| 1 |
IC50 > 10000 nM
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CP0504958
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N-[(2S)-2-(3-chlorophenyl)-4-(2-phenylethylamino)butyl]-N-methylbenzenesulfonamide
Show/Hide
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C25H29ClN2O2S
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1
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| 1 |
IC50 > 10000 nM
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CP0409397
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1'-[4-phenyl-1-phenylsulfonyl-(3S,4S)-tetrahydro-1H-3-pyrrolylmethyl]spiro[2,3-dihydrobenzo[b]thiophene-3,4'-(hexahydropyridine)]
Show/Hide
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C29H32N2O2S2
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1
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| 1 |
IC50 > 10000 nM
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CP0515886
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1'-(4-phenyl-1-phenylsulfonyltetrahydro-1H-3-pyrrolylmethyl)spiro[2,3-dihydrobenzo[b]thiophene-3,4'-(hexahydropyridine)]
Show/Hide
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C29H32N2O2S2
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1
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| 1 |
IC50 > 10000 nM
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CP0536974
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1'-[4-phenyl-1-phenylsulfonyl-(3R,4S)-tetrahydro-1H-3-pyrrolylmethyl]spiro[2,3-dihydrobenzo[b]thiophene-3,4'-(hexahydropyridine)1,1-dioxide]
Show/Hide
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C29H32N2O4S2
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1
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| 1 |
IC50 > 10000 nM
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CP0537462
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1'-[4-phenyl-1-phenylsulfonyl-(3R,4R)-tetrahydro-1H-3-pyrrolylmethyl]spiro[2,3-dihydrobenzo[b]thiophene-3,4'-(hexahydropyridine)1,1-dioxide]
Show/Hide
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C29H32N2O4S2
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1
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| 1 |
IC50 > 10000 nM
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CP0869816
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(S)-1-butyl-3-(cyclohexylmethyl)-9-(3-phenoxyphenethyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C33H46ClN3O3
|
1
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| 1 |
IC50 = 10000 nM
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CP0388284
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methyl 4-benzyl-1-[(3S)-3-(cyclobutanecarbonylamino)-3-naphthalen-1-ylpropyl]piperidine-4-carboxylate
Show/Hide
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C32H38N2O3
|
1
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| 1 |
IC50 > 10000 nM
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|
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CP0388285
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methyl 4-benzyl-1-[(3S)-3-(cyclobutanecarbonylamino)-3-[4-(trifluoromethyl)phenyl]propyl]piperidine-4-carboxylate
Show/Hide
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C29H35F3N2O3
|
1
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| 1 |
IC50 = 10000 nM
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CP0439063
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N-[(1S)-3-[4-[4-[acetyl(propan-2-yl)amino]phenyl]piperazin-1-yl]-1-[4-(trifluoromethyl)phenyl]propyl]cyclohexanecarboxamide
Show/Hide
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C32H43F3N4O2
|
1
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| 1 |
IC50 > 10000 nM
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CP0489498
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N-[(1S)-3-[4-[4-[benzyl(propan-2-yl)amino]phenyl]piperazin-1-yl]-1-[4-(trifluoromethyl)phenyl]propyl]cyclohexanecarboxamide
Show/Hide
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C37H47F3N4O
|
1
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| 1 |
IC50 > 10000 nM
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CP0508028
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N-[(1S)-3-[4-benzyl-4-(hydroxymethyl)piperidin-1-yl]-1-[4-(trifluoromethyl)phenyl]propyl]cyclobutanecarboxamide
Show/Hide
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C28H35F3N2O2
|
1
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| 1 |
IC50 > 10000 nM
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CP0912149
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endo-4-Fluoro-N-((S)-3-(3-(2-methyl-3H-imidazo[4,5-b]pyridin-3-yl)-8-aza-bicyclo[3.2.1]octan-8-yl)-1-(naphthalen-1-yl)propyl)benzamide
Show/Hide
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C34H34FN5O
|
1
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| 1 |
IC50 = 10000 nM
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|
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CP0288884
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1-(1-{3-[1-Benzyl-3-(3,4-dichloro-phenyl)-6-oxo-piperidin-3-yl]-propyl}-piperidin-4-yl)-1,3-dihydro-benzoimidazol-2-one
Show/Hide
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C33H36Cl2N4O2
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1
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| 1 |
IC50 = 19952.62 nM
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CP0940316
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exo-4-(3,4-Dichloro-phenyl)-4-{3-[3-(2-methyl-benzoimidazol-1-yl)-8-aza-bicyclo[3.2.1]oct-8-yl]-propyl}-piperidine-1-carboxylic acid tert-butyl ester
Show/Hide
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C34H44Cl2N4O2
|
1
|
| 1 |
IC50 = 19952.62 nM
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CP0890907
|
4-[4-({(3R)-3-[(R)-Cyclohexyl(hydroxy)methyl]-1-ethyl-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]-N-methylbenzamidehydrochloride
Show/Hide
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C32H43ClN4O5
|
1
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| 1 |
IC50 = 20000 nM
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CP0486845
|
8-[2-[1-(benzenesulfonyl)-3-(3,4-dichlorophenyl)pyrrolidin-3-yl]oxyethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
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C31H34Cl2N4O4S
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1
|
| 1 |
IC50 = 20417.38 nM
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CP0905747
|
trans-4-[4-({(3R)-1-Butyl-3-[(s)-hydroxy(4-hydroxycyclohexyl)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzoic acid hydrochloride
Show/Hide
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C33H44ClN3O7
|
1
|
| 1 |
IC50 = 23000 nM
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CP0920915
|
4-(4-(((R)-3-((R)-cyclohexyl(hydroxy)methyl)-1-ethyl-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl)methyl)phenoxy)benzoic acid hydrochloride
Show/Hide
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C31H40ClN3O6
|
1
|
| 1 |
IC50 = 23000 nM
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|
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|
CP0888360
|
4-[4-({(3R)-1-Butyl-3-[(R)-cyclobutyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzoic acid hydrochloride
Show/Hide
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C31H40ClN3O6
|
1
|
| 1 |
IC50 = 25000 nM
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|
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|
CP0888361
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N-{4-[4-({(3R)-1-Butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]phenyl}methanesulfonamide hydrochloride
Show/Hide
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C33H47ClN4O6S
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1
|
| 1 |
IC50 = 26000 nM
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CP0894367
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4-[4-({(3R)-3-[(R)-Cyclohexyl(hydroxy)methyl]-2,5-dioxo-1-propyl-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]-N-methylbenzamide hydrochloride
Show/Hide
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C33H45ClN4O5
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1
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| 1 |
IC50 = 28000 nM
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|
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CP0888357
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4-[4-({(3R)-3-[(R)-Cyclohexyl(hydroxy)methyl]-2,5-dioxo-1-propyl-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzoic acid hydrochloride
Show/Hide
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C32H42ClN3O6
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1
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| 1 |
IC50 = 30000 nM
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CP0441129
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1-cyclohexyl-8-[3-[3-(3,4-dichlorophenyl)-1-(furan-2-carbonyl)pyrrolidin-3-yl]propyl]-1,3,8-triazaspiro[4.5]decan-4-one
Show/Hide
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C31H40Cl2N4O3
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1
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| 1 |
IC50 > 31622.78 nM
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CP0486842
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4-anilino-1-[3-[1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]piperidine-4-carboxamide
Show/Hide
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C33H38Cl2N4O2
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1
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| 1 |
IC50 > 31622.78 nM
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CP0511278
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8-[3-[3-(3,4-dichlorophenyl)-1-(furan-2-carbonyl)pyrrolidin-3-yl]propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decane-2,4-dione
Show/Hide
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C31H32Cl2N4O4
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1
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| 1 |
IC50 > 31622.78 nM
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CP0921833
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exo-tert-butyl 4-(3-(3-(2-methyl-1H-benzo[d]imidazol-1-yl)-8-aza-bicyclo[3.2.1]octan-8-yl)propyl)-4-phenylpiperidine-1-carboxylate
Show/Hide
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C34H46N4O2
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1
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| 1 |
IC50 > 31622.78 nM
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CP0888359
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4-[4-({(3R)-1-Butyl-3-[(R)-cycloheptyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzoic acid hydrochloride
Show/Hide
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C34H46ClN3O6
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1
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| 1 |
IC50 = 32000 nM
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CP0920538
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4-[4-({(3R)-1-Butyl-3-[(R)-cyclopentyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzoic acid hydrochloride
Show/Hide
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C32H42ClN3O6
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1
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| 1 |
IC50 = 33000 nM
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CP0920540
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4-(4-{[(3R)-3-[(R)-Cyclohexyl(hydroxy)methyl]-1-(2-methoxyethyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl]methyl}phenoxy)-N-methylbenzamidehydrochloride
Show/Hide
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C33H45ClN4O6
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1
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| 1 |
IC50 = 33000 nM
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CP0910786
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(3R)-1-Butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-9-{4-[4-(methylsulfonyl)phenoxy]benzyl}-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C33H46ClN3O6S
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1
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| 1 |
IC50 = 34000 nM
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CP0893188
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4-[4-({(3R)-1-Butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]-N-methylbenzamidehydrochloride
Show/Hide
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C34H47ClN4O5
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1
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| 1 |
IC50 = 38000 nM
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CP0922379
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4-[4-({(3R)-1-Butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzamide hydrochloride
Show/Hide
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C33H45ClN4O5
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1
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| 1 |
IC50 = 39000 nM
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CP0851854
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4-(4-{[(3R)-3-[(R)-Cyclohexyl(hydroxy)methyl]-2,5-dioxo-1-(2,2,2-trifluoroethyl)-1,4,9-triazaspiro[5.5]undec-9-yl]methyl}phenoxy)-N-methylbenzamide hydrochloride
Show/Hide
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C32H40ClF3N4O5
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1
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| 1 |
IC50 = 46000 nM
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|
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CP0902872
|
4-[4-({(3R)-1-Butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzenesulfonamide hydrochloride
Show/Hide
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C32H45ClN4O6S
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1
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| 1 |
IC50 = 48000 nM
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CP0920539
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4-[4-({(3R)-1-Butyl-3-[(1R)-1-hydroxy-2-methylpropyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzoic acid hydrochloride
Show/Hide
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C30H40ClN3O6
|
1
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| 1 |
IC50 = 48000 nM
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|
CP0919865
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4-(4-(((R)-3-((R)-cyclohexyl(hydroxy)methyl)-1-methyl-2,5-dioxo-1,4,9-triazaspiro[5.5]undecan-9-yl)methyl)phenoxy)benzoic acid hydrochloride
Show/Hide
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C30H38ClN3O6
|
1
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| 1 |
IC50 = 50000 nM
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CP0910788
|
4-[4-({(3R)-3-[(R)-Cyclohexyl(hydroxy)methyl]-1-methyl-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]-N-methylbenzamide hydrochloride
Show/Hide
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C31H41ClN4O5
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1
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| 1 |
IC50 = 59000 nM
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CP0888356
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4-[4-({(3R)-3-[(R)-Cyclohexyl(hydroxy)methyl]-2,5-dioxo-1-pentyl-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]-N-methylbenzamide hydrochloride
Show/Hide
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C35H49ClN4O5
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1
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| 1 |
IC50 = 68000 nM
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CP0920535
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(3R)-1-Butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-9-[4-(4-hydroxyphenoxy)benzyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
|
C32H44ClN3O5
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1
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| 1 |
IC50 = 68000 nM
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CP0905748
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4-[4-({(3R)-1-Butyl-3-[(R)-cyclopropyl(hydroxy)methyl]-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl}methyl)phenoxy]benzoic acid hydrochloride
Show/Hide
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C30H38ClN3O6
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1
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| 1 |
IC50 = 81000 nM
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CP0910787
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(3R)-1-Butyl-3-[(R)-cyclohexyl(hydroxy)methyl]-9-[4-(4-methoxyphenoxy)benzyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
Show/Hide
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C33H46ClN3O5
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1
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| 1 |
IC50 = 91000 nM
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CP0854292
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[1-((2S,3aS,4S,5S)-2,4-Diphenyl-hexahydro-pyrrolo[1,2-b]isoxazol-5-ylmethyl)-piperidin-4-yl]-ethyl-carbamic acid benzyl ester
Show/Hide
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C34H41N3O3
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1
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| 1 |
IC50 ~ 27 nM
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CP0090931
|
4-(trifluoromethyl)benzyl allyl(1-(((3S,4R)-1-(cyclopentanecarbonyl)-4-hydroxy-4-phenylpyrrolidin-3-yl)methyl)piperidin-4-yl)carbamate
Show/Hide
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C34H42F3N3O4
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1
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| 1 |
IC50 > 30 nM
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CP0500745
|
N-methyl-N-[(2S)-4-[4-[(5S)-2-oxo-5-phenyl-1,3-oxazolidin-3-yl]piperidin-1-yl]-2-phenylbutyl]benzenesulfonamide
Show/Hide
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C31H37N3O4S
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1
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| 1 |
IC50 > 100 nM
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CP0373908
|
5-((3aR,6aS)-5-((S)-4-((R)-2-methoxy-1-(4-(trifluoromethyl)phenyl)ethyl)-3-methylpiperazin-1-yl)octahydrocyclopenta[c]pyrrole-2-carbonyl)-4,6-dimethylpicolinonitrile
Show/Hide
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C31H38F3N5O2
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1
|
| 1 |
IC50 > 500 nM
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CP0373983
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(4,6-dimethylpyrimidin-5-yl)((3aR,6aS)-5-((S)-4-((R)-2-methoxy-1-(4-(trifluoromethyl)phenyl)ethyl)-3-methylpiperazin-1-yl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)methanone
Show/Hide
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C29H38F3N5O2
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1
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| 1 |
IC50 > 500 nM
|
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CP0463745
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(2,4-dimethylpyridin-3-yl)((3aR,6aS)-5-((S)-4-((R)-2-methoxy-1-(4-(trifluoromethyl)phenyl)ethyl)-3-methylpiperazin-1-yl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)methanone
Show/Hide
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C30H39F3N4O2
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1
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| 1 |
IC50 > 500 nM
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CP0439623
|
4-Phenyl-1-[(3S,4S)-4-phenyl-1-(3-phenyl-propyl)-pyrrolidin-3-ylmethyl]-piperidine
Show/Hide
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C31H38N2
|
1
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| 1 |
IC50 > 1000 nM
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|
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CP0454828
|
(4-Methoxy-phenyl)-[(3S,4S)-3-phenyl-4-(4-phenyl-piperidin-1-ylmethyl)-pyrrolidin-1-yl]-methanone
Show/Hide
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C30H34N2O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
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CP0456938
|
1-[(3S,4S)-1-Benzyl-4-(4-chloro-phenyl)-pyrrolidin-3-ylmethyl]-4-phenyl-piperidine
Show/Hide
|
C29H33ClN2
|
1
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| 1 |
IC50 > 1000 nM
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CP0460037
|
1-[(3S,4S)-1-Benzyl-4-(3-bromo-phenyl)-pyrrolidin-3-ylmethyl]-4-phenyl-piperidine
Show/Hide
|
C29H33BrN2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
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CP0461311
|
1-((3S,4S)-1-Benzyl-4-biphenyl-3-yl-pyrrolidin-3-ylmethyl)-4-phenyl-piperidine
Show/Hide
|
C35H38N2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
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CP0509630
|
3-[(3S,4S)-1-Benzyl-4-(4-phenyl-piperidin-1-ylmethyl)-pyrrolidin-3-yl]-benzoic acid methyl ester
Show/Hide
|
C31H36N2O2
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
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CP0528962
|
1-[(3S,4S)-1-Benzyl-4-(2-chloro-phenyl)-pyrrolidin-3-ylmethyl]-4-phenyl-piperidine
Show/Hide
|
C29H33ClN2
|
1
|
| 1 |
IC50 > 1000 nM
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|
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CP0555047
|
1-((3S,4S)-1,4-Diphenyl-pyrrolidin-3-ylmethyl)-4-phenyl-piperidine
Show/Hide
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C28H32N2
|
1
|
| 1 |
IC50 > 1000 nM
|
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CP0377893
|
methyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]carbamate
Show/Hide
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C24H33N3O4S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
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CP0409742
|
(4-Benzylamino-4'-methyl-[1,4']bipiperidinyl-1'-yl)-(2,6-dimethyl-phenyl)-methanone
Show/Hide
|
C27H37N3O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
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CP0395771
|
(4R)-1-cyclohexyl-3-[1-[[1-(2-methylphenyl)piperidin-4-yl]methyl]piperidin-4-yl]-4-phenylimidazolidin-2-one
Show/Hide
|
C33H46N4O
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
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CP0387345
|
1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-ethyl-N-phenylpiperidine-4-carboxamide
Show/Hide
|
C31H41ClN4O3
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
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CP0437798
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1-[3-(N-(1-acetylpiperidine-4-carbonyl)-3-chloroanilino)propyl]-N-phenylpiperidine-4-carboxamide
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C29H37ClN4O3
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1
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| 1 |
IC50 > 1000 nM
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CP0502549
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N-[(2S)-4-(1,2,3,3a,4,6,7,7a-octahydropyrrolo[3,2-c]pyridin-5-yl)-2-methyl-2-phenylbutyl]-N-methylbenzenesulfonamide
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C25H35N3O2S
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1
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| 1 |
IC50 > 2000 nM
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CP0445416
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2-({[1'-(2,4-Dimethyl-1-oxy-pyridine-3-carbonyl)-4'-methyl-[1,4']bipiperidinyl-4-yl]-phenyl-amino}-methyl)-benzonitrile
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C33H39N5O2
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1
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| 1 |
IC50 > 3000 nM
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CP0883021
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1-(3-hydroxy-butyl)-3-isobutyl-9-(4-phenoxy-benzyl)-1,4,9-triaza-spiro[5.5]undecane-2,5-dione hydrochloride
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C29H40ClN3O4
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1
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| 1 |
IC50 > 3000 nM
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CP0903579
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rac-Ethyl 4-[1-butyl-3-(cyclohexylmethyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undec-9-yl]benzoate hydrochloride
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C28H42ClN3O4
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1
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| 1 |
IC50 > 3000 nM
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CP0918697
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(3S)-1-Butyl-3-(cyclohexylmethyl)-9-[2-(4-phenoxyphenyl)ethyl]-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
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C33H46ClN3O3
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1
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| 1 |
IC50 > 3000 nM
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CP0920373
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rac-1-Butyl-3-(3-cyclohexylpropyl)-9-(4-phenoxybenzyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
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C34H48ClN3O3
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1
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| 1 |
IC50 > 3000 nM
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CP0927949
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rac-[1-Butyl-2,5-dioxo-9-(4-phenoxybenzyl)-1,4,9-triazaspiro[5.5]undec-3-yl]acetic acid hydrochloride
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C27H34ClN3O5
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1
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| 1 |
IC50 > 3000 nM
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CP0494684
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[4-[2-[7-(2-methylbenzimidazol-1-yl)-3-oxa-9-azabicyclo[3.3.1]nonan-9-yl]ethyl]-4-phenylpiperidin-1-yl]-phenylmethanone
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C35H40N4O2
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1
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| 1 |
IC50 > 3162.28 nM
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CP0372862
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1'-[3-(3,4-dichlorophenyl)-4-methyl(3-thienyl)sulfonamido-(3S)-butyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]
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C27H30Cl2N2O3S3
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1
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| 1 |
IC50 > 4000 nM
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CP0309398
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(3,5-Dichloro-pyridin-4-yl)-(4-methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromethyl-phenyl)-ethyl]-piperazin-1-yl}-piperidin-1-yl)-methanone
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C26H31Cl2F3N4O
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1
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| 1 |
Ki = 0.7 nM
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CP0097212
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(2,4-Dimethyl-pyridin-3-yl)-(4-methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromethyl-phenyl)-ethyl]-piperazin-1-yl}-piperidin-1-yl)-methanone
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C28H37F3N4O
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1
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| 1 |
Ki = 2 nM
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CP0298393
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(3,5-Dichloro-1-oxy-pyridin-4-yl)-(4-methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromethyl-phenyl)-ethyl]-piperazin-1-yl}-piperidin-1-yl)-methanone
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C26H31Cl2F3N4O2
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1
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| 1 |
Ki = 2.7 nM
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CP0097311
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(4,6-Dimethyl-pyrimidin-5-yl)-(4-methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromethyl-phenyl)-ethyl]-piperazin-1-yl}-piperidin-1-yl)-methanone
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C27H36F3N5O
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1
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| 1 |
Ki = 3 nM
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CP0184495
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(3,5-Dimethyl-pyridin-4-yl)-(4-methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromethyl-phenyl)-ethyl]-piperazin-1-yl}-piperidin-1-yl)-methanone
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C28H37F3N4O
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1
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| 1 |
Ki = 5.23 nM
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CP0180533
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(2,4-Dimethyl-1-oxy-pyridin-3-yl)-(4-methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromethyl-phenyl)-ethyl]-piperazin-1-yl}-piperidin-1-yl)-methanone
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C28H37F3N4O2
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1
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| 1 |
Ki = 7 nM
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CP0259418
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(4,6-Dimethyl-2-trifluoromethyl-pyrimidin-5-yl)-(4-methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromethyl-phenyl)-ethyl]-piperazin-1-yl}-piperidin-1-yl)-methanone
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C28H35F6N5O
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1
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| 1 |
Ki = 10 nM
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CP0329792
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(4-Methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromethyl-phenyl)-ethyl]-piperazin-1-yl}-piperidin-1-yl)-(2,4,6-trimethyl-pyrimidin-5-yl)-methanone
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C28H38F3N5O
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1
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| 1 |
Ki = 10 nM
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CP0041540
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(4,6-Dimethyl-pyrimidin-5-yl)-(4-{(S)-4-[(S)-1-(4-iodo-phenyl)-ethyl]-3-methyl-piperazin-1-yl}-4-methyl-piperidin-1-yl)-methanone
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C26H36IN5O
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1
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| 1 |
Ki = 11 nM
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CP0189524
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(4,6-Dimethyl-pyrimidin-5-yl)-(4-methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromethoxy-phenyl)-ethyl]-piperazin-1-yl}-piperidin-1-yl)-methanone
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C27H36F3N5O2
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1
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| 1 |
Ki = 11 nM
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CP0197925
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(2-Methoxy-4,6-dimethyl-pyrimidin-5-yl)-(4-methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromethyl-phenyl)-ethyl]-piperazin-1-yl}-piperidin-1-yl)-methanone
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C28H38F3N5O2
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1
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| 1 |
Ki = 11 nM
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CP0044922
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(4,6-Dimethyl-2-phenyl-pyrimidin-5-yl)-(4-methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromethyl-phenyl)-ethyl]-piperazin-1-yl}-piperidin-1-yl)-methanone
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C33H40F3N5O
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1
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| 1 |
Ki = 12 nM
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CP0101733
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(3,5-Dimethyl-1-oxy-pyridin-4-yl)-(4-methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromethyl-phenyl)-ethyl]-piperazin-1-yl}-piperidin-1-yl)-methanone
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C28H37F3N4O2
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1
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| 1 |
Ki = 18 nM
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CP0112911
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4-((S)-1-{(S)-4-[1-(4,6-Dimethyl-pyrimidine-5-carbonyl)-4-methyl-piperidin-4-yl]-2-methyl-piperazin-1-yl}-ethyl)-benzonitrile
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C27H36N6O
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1
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| 1 |
Ki = 20 nM
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CP0358248
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(2-Amino-4,6-dimethyl-pyrimidin-5-yl)-(4-methyl-4-{(S)-3-methyl-4-[(S)-1-(4-trifluoromethyl-phenyl)-ethyl]-piperazin-1-yl}-piperidin-1-yl)-methanone
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C27H37F3N6O
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1
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| 1 |
Ki = 38 nM
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