Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(5S)-5-butyl-9-((3aR,6aS)-2-(4,6-dimethylpyrimidine-5-carbonyl)-5-methyloctahydrocyclopenta[c]pyrrol-5-yl)-3-((tetrahydro-2H-pyran-4-yl)methyl)-1-oxa-3,9-diazaspiro[5.5]undecan-2-one
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 PubChem ID
CID: 46882078
Canonical SMILES
CCCC[C@H]1CN(CC2CCOCC2)C(=O)OC11CCN(CC1)C1(C)C[C@@H]2CN(C[C@@H]2C1)C(=O)c1c(C)ncnc1C
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Compound Formula C33H51N5O4
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P51681
Gene Name
CCR5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 25 nM
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   LI
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   TS