Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(+/-)-1-butyl-3-isobutyl-9-(4-phenoxybenzyl)-1,4,9-triazaspiro[5.5]undecane-2,5-dione hydrochloride
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 PubChem ID
CID: 10301330
SID: 15308030
Canonical SMILES
CCCCN1C(=O)C(CC(C)C)NC(=O)C12CCN(Cc1ccc(Oc3ccccc3)cc1)CC2.Cl
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Compound Formula C29H40ClN3O3
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P51681
Gene Name
CCR5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  3
1
IC50 = 8.3 nM
   TI
   LI
   LO
   TS
2
IC50 = 94 nM
   TI
   LI
   LO
   TS
3
IC50 = 120 nM
   TI
   LI
   LO
   TS
CL000149 HOS
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 851.14 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 83 nM