Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4,6-Dimethyl-2-pyridin-4-yl-pyrimidin-5-yl)-(4-diphenylamino-4'-methyl-[1,4']bipiperidinyl-1'-yl)-methanone
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 PubChem ID
CID: 3008932
SID: 15135505
Canonical SMILES
Cc1nc(nc(C)c1C(=O)N1CCC(C)(CC1)N1CCC(CC1)N(c1ccccc1)c1ccccc1)-c1ccncc1
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Compound Formula C35H40N6O
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P51681
Gene Name
CCR5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 30 nM
   TI
   LI
   LO
   TS
CL000233 L1.2
 Cell Line Info 
Mus musculus (Mouse)  1
1
IC50 = 24.6 nM
   TI
   LI
   LO
   TS