Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-Cyclopropyl-2-[(3S,4S)-3-((R)-3-fluoro-phenyl)-4-(4-{2-[2-(4-fluoro-phenyl)-[1,3]dioxolan-2-yl]-ethyl}-piperidin-1-ylmethyl)-pyrrolidin-1-yl]-propionic acid
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 PubChem ID
CID: 44274022
Canonical SMILES
OC(=O)[C@@H](CC1CC1)N1C[C@H](CN2CCC(CCC3(OCCO3)c3ccc(F)cc3)CC2)[C@H](C1)c1cccc(F)c1
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Compound Formula C33H42F2N2O4
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P51681
Gene Name
CCR5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 3.7 nM
   TI
   LI
   LO
   TS