General Information of the Compound
Compound ID
CP0453370
Compound Name
1-((3S,4S)-1-Benzyl-4-phenyl-pyrrolidin-3-ylmethyl)-4-phenyl-piperidine
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Structure
Formula
C29H34N2
Molecular Weight
410.605
Canonical SMILES
C([C@H]1CN(Cc2ccccc2)C[C@@H]1c1ccccc1)N1CCC(CC1)c1ccccc1
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InChI
InChI=1S/C29H34N2/c1-4-10-24(11-5-1)20-31-22-28(29(23-31)27-14-8-3-9-15-27)21-30-18-16-26(17-19-30)25-12-6-2-7-13-25/h1-15,26,28-29H,16-23H2/t28-,29+/m0/s1
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InChIKey
UBLXYTLHCHAYRI-URLMMPGGSA-N
Physicochemical Property
logP
5.7818
Rotatable Bonds
6
Heavy Atom Count
31
Polar Areas
6.48
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
2
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 456374
ChEMBL ID
CHEMBL90015
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00903, C-C chemokine receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 255 nM
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