General Information of the Compound
Compound ID
CP0420023
Compound Name
1-Allyl-1-[1-(3,3-diphenyl-propyl)-piperidin-4-yl]-3-(3-methyl-benzyl)-urea
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Structure
Formula
C32H39N3O
Molecular Weight
481.684
Canonical SMILES
Cc1cccc(CNC(=O)N(CC=C)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)c1
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InChI
InChI=1S/C32H39N3O/c1-3-20-35(32(36)33-25-27-12-10-11-26(2)24-27)30-17-21-34(22-18-30)23-19-31(28-13-6-4-7-14-28)29-15-8-5-9-16-29/h3-16,24,30-31H,1,17-23,25H2,2H3,(H,33,36)
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InChIKey
ACQOHKAMPJYKEH-UHFFFAOYSA-N
Physicochemical Property
logP
6.37922
Rotatable Bonds
10
Heavy Atom Count
36
Polar Areas
35.58
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
2
Complexity
36

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44392196
ChEMBL ID
CHEMBL183261
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00903, C-C chemokine receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 240 nM
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