Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[1-[[(3S,4R)-1-(cyclopentanecarbonyl)-4-(4-fluorophenyl)-4-hydroxypyrrolidin-3-yl]methyl]piperidin-4-yl]-2-[4-(methylsulfamoyl)phenyl]-N-prop-2-enylacetamide
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 PubChem ID
CID: 49864972
Canonical SMILES
CNS(=O)(=O)c1ccc(CC(=O)N(CC=C)C2CCN(C[C@H]3CN(C[C@]3(O)c3ccc(F)cc3)C(=O)C3CCCC3)CC2)cc1
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Compound Formula C34H45FN4O5S
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P51681
Gene Name
CCR5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 11.17 nM
   TI
   LI
   LO
   TS