Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[[4-[(5R)-3-cyclohexyl-2-oxo-5-phenylimidazolidin-1-yl]piperidin-1-yl]methyl]-N-methylbenzamide
    Show/Hide
 PubChem ID
CID: 72712597
Canonical SMILES
CNC(=O)c1ccc(CN2CCC(CC2)N2[C@@H](CN(C3CCCCC3)C2=O)c2ccccc2)cc1
    Show/Hide
Compound Formula C29H38N4O2
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P51681
Gene Name
CCR5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 62.7 nM
   TI
   LI
   LO
   TS
CL000131 HEK293-F
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 15.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 85.1 nM
   TI
   LI
   LO
   TS