General Information of the Compound
Compound ID
CP0918698
Compound Name
rac-Benzyl 1-butyl-3-(cyclohexylmethyl)-2,5-dioxo-1,4,9-triazaspiro[5.5]undecane-9-carboxylate hydrochloride
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Structure
Formula
C27H40ClN3O4
Molecular Weight
506.087
Canonical SMILES
CCCCN1C(=O)C(CC2CCCCC2)NC(=O)C12CCN(C(=O)OCc1ccccc1)CC2.Cl
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InChI
InChI=1S/C27H39N3O4.ClH/c1-2-3-16-30-24(31)23(19-21-10-6-4-7-11-21)28-25(32)27(30)14-17-29(18-15-27)26(33)34-20-22-12-8-5-9-13-22;/h5,8-9,12-13,21,23H,2-4,6-7,10-11,14-20H2,1H3,(H,28,32);1H
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InChIKey
ZWOHXLJDFDDWMU-UHFFFAOYSA-N
Physicochemical Property
logP
4.6771
Rotatable Bonds
7
Heavy Atom Count
35
Polar Areas
78.95
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 49799662
ChEMBL ID
CHEMBL1173708
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00903, C-C chemokine receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 3000 nM
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