General Information of the Compound
Compound ID
CP0883021
Compound Name
1-(3-hydroxy-butyl)-3-isobutyl-9-(4-phenoxy-benzyl)-1,4,9-triaza-spiro[5.5]undecane-2,5-dione hydrochloride
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Structure
Formula
C29H40ClN3O4
Molecular Weight
530.109
Canonical SMILES
CC(C)CC1NC(=O)C2(CCN(Cc3ccc(Oc4ccccc4)cc3)CC2)N(CCC(C)O)C1=O.Cl
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InChI
InChI=1S/C29H39N3O4.ClH/c1-21(2)19-26-27(34)32(16-13-22(3)33)29(28(35)30-26)14-17-31(18-15-29)20-23-9-11-25(12-10-23)36-24-7-5-4-6-8-24;/h4-12,21-22,26,33H,13-20H2,1-3H3,(H,30,35);1H
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InChIKey
BGVVHPOHFQGXHV-UHFFFAOYSA-N
Physicochemical Property
logP
4.3793
Rotatable Bonds
9
Heavy Atom Count
37
Polar Areas
82.11
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
5
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 21925880
ChEMBL ID
CHEMBL538336
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00903, C-C chemokine receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 > 3000 nM
   TI
   LI
   LO
   TS