General Information of the Compound
Compound ID
CP0249044
Compound Name
tert-butyl N-[1-[(3S)-4-[benzenesulfonyl(methyl)amino]-3-phenylbutyl]piperidin-4-yl]carbamate
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Structure
Formula
C27H39N3O4S
Molecular Weight
501.693
Canonical SMILES
CN(C[C@@H](CCN1CCC(CC1)NC(=O)OC(C)(C)C)c1ccccc1)S(=O)(=O)c1ccccc1
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InChI
InChI=1S/C27H39N3O4S/c1-27(2,3)34-26(31)28-24-16-19-30(20-17-24)18-15-23(22-11-7-5-8-12-22)21-29(4)35(32,33)25-13-9-6-10-14-25/h5-14,23-24H,15-21H2,1-4H3,(H,28,31)/t23-/m1/s1
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InChIKey
SBGKQWHYEYPEJC-HSZRJFAPSA-N
Physicochemical Property
logP
4.4701
Rotatable Bonds
9
Heavy Atom Count
35
Polar Areas
78.95
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
35

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44461790
ChEMBL ID
CHEMBL421527
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00903, C-C chemokine receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1000 nM