Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2R,4S)-2-[(2S,3S)-3-{4-[5-(3,5-Bis-trifluoromethyl-benzyl)-2-ethyl-2H-pyrazol-3-yl]-piperidin-1-ylmethyl}-4-(3-fluoro-phenyl)-pyrrolidin-1-yl]-3-methyl-pentanoic acid
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 PubChem ID
CID: 516206
Canonical SMILES
CC[C@H](C)[C@@H](N1C[C@H](CN2CCC(CC2)c2cc(Cc3cc(cc(c3)C(F)(F)F)C(F)(F)F)nn2CC)[C@H](C1)c1cccc(F)c1)C(O)=O
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Compound Formula C36H43F7N4O2
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P51681
Gene Name
CCR5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 2.1 nM
   TI
   LI
   LO
   TS