Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3a'S,4'S,5'S)-5'-phenyl-4'-((4-phenylpiperidin-1-yl)methyl)tetrahydro-3'H-spiro[cyclohexane-1,2'-pyrrolo[1,2-b]isoxazole]
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 PubChem ID
CID: 44373768
Canonical SMILES
C([C@H]1[C@@H]2CC3(CCCCC3)ON2C[C@@H]1c1ccccc1)N1CCC(CC1)c1ccccc1
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Compound Formula C29H38N2O
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P51681
Gene Name
CCR5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS