Brief Information of the Compound and Protein
Compound Name
 Compound Info 
endo-4-Fluoro-N-((S)-3-(3-(2-methyl-3H-imidazo[4,5-b]pyridin-3-yl)-8-aza-bicyclo[3.2.1]octan-8-yl)-1-(naphthalen-1-yl)propyl)benzamide
    Show/Hide
Canonical SMILES
Cc1nc2cccnc2n1[C@H]1C[C@H]2CC[C@@H](C1)N2CC[C@H](NC(=O)c1ccc(F)cc1)c1cccc2ccccc12
    Show/Hide
Compound Formula C34H34FN5O
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 5
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P51681
Gene Name
CCR5
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS