General Information of the Compound
Compound ID
CP0423587
Compound Name
benzyl N-[1-[[(2S,3aS,4S,5S)-2,5-diphenyl-2,3,3a,4,5,6-hexahydropyrrolo[1,2-b][1,2]oxazol-4-yl]methyl]piperidin-4-yl]-N-ethylcarbamate
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Structure
Formula
C34H41N3O3
Molecular Weight
539.72
Canonical SMILES
CCN(C1CCN(C[C@H]2[C@@H]3C[C@H](ON3C[C@@H]2c2ccccc2)c2ccccc2)CC1)C(=O)OCc1ccccc1
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InChI
InChI=1S/C34H41N3O3/c1-2-36(34(38)39-25-26-12-6-3-7-13-26)29-18-20-35(21-19-29)23-31-30(27-14-8-4-9-15-27)24-37-32(31)22-33(40-37)28-16-10-5-11-17-28/h3-17,29-33H,2,18-25H2,1H3/t30-,31-,32+,33+/m1/s1
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InChIKey
WIIDGEGJDZSGHC-FYZVQMPESA-N
Physicochemical Property
logP
6.2703
Rotatable Bonds
8
Heavy Atom Count
40
Polar Areas
45.25
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44374136
ChEMBL ID
CHEMBL158438
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00903, C-C chemokine receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 46 nM
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