General Information of the Compound
Compound ID
CP0392399
Compound Name
N-[1-(3,3-diphenylpropyl)piperidin-4-yl]-2-(4-nitrophenyl)-N-prop-2-enylacetamide
    Show/Hide
Structure
Formula
C31H35N3O3
Molecular Weight
497.639
Canonical SMILES
[O-][N+](=O)c1ccc(CC(=O)N(CC=C)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1
    Show/Hide
InChI
InChI=1S/C31H35N3O3/c1-2-20-33(31(35)24-25-13-15-29(16-14-25)34(36)37)28-17-21-32(22-18-28)23-19-30(26-9-5-3-6-10-26)27-11-7-4-8-12-27/h2-16,28,30H,1,17-24H2
    Show/Hide
InChIKey
AKEHDJQAUFRJKQ-UHFFFAOYSA-N
Physicochemical Property
logP
5.8385
Rotatable Bonds
11
Heavy Atom Count
37
Polar Areas
66.69
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 44392094
ChEMBL ID
CHEMBL426960
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00903, C-C chemokine receptor type 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 180 nM
   TI
   LI
   LO
   TS